A corticosteroid injection performed within the first 5 weeks after anterior cruciate ligament injury resulted in significantly less of an increase in cartilage degradation markers in comparison to placebo injections.... Read more »
Lattermann, C., Jacobs, C., Proffitt Bunnell, M., Huston, L., Gammon, L., Johnson, D., Reinke, E., Huebner, J., Kraus, V., & Spindler, K. (2017) A Multicenter Study of Early Anti-inflammatory Treatment in Patients With Acute Anterior Cruciate Ligament Tear. The American Journal of Sports Medicine, 45(2), 325-333. DOI: 10.1177/0363546516666818
MedicalResearch.com Interview with: Prof. dr. D.L.P. Baeten MD Clinical Immunology and Rheumatology Academic Medical Center University of Amsterdam Amsterdam, The Netherlands Medical Research: What is the background for this study? What are the main findings? Prof. Baeten: Ankylosing spondylitis is … Continue reading →
The post Immunotherapy with IL-17 Blocker Secukinumab Improves Ankylosing Spondylitis appeared first on MedicalResearch.com.
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Prof. dr. D.L.P. Baeten. (2015) Immunotherapy with IL-17 Blocker Secukinumab Improves Ankylosing Spondylitis. MedicalResearch.com. info:/
MedicalResearch.com Interview with: Anja Bye, PhD, Senior Researcher Cardiac Exercise Research Group (CERG) K.G. Jebsen Center of Exercise in Medicine National Council of Cardiovascular Disease Department of Circulation and Medical Imaging Medical Faculty Norwegian University of Science and Technology Medical … Continue reading →
The post Pilot Study Tests High Intensity Exercise in Women With Rheumatic Disease appeared first on MedicalResearch.com.
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Anja Bye, PhD,. (2015) Pilot Study Tests High Intensity Exercise in Women With Rheumatic Disease. MedicalResearch.com. info:/
MedicalResearch.com Interview with: Cécile Gaujoux-Viala, MD, PhD Université Montpellier I Chef de Service de Rhumatologie CHU de Nîmes Carémeau France Medical Research: What is the background for this study? Response: Chronic inflammatory rheumatic diseases – such as rheumatoid arthritis (RA), … Continue reading →
The post Biologics in Rheumatic Disease Reduce Missed Workdays appeared first on MedicalResearch.com Medical Research Interviews and News.
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Cécile Gaujoux-Viala, MD, PhD, Université Montpellier I, Chef de Service de Rhumatologie, CHU de Nîmes Carémeau, & France. (2015) Biologics Reduce Missed Workdays in Rheumatic Disease. MedicalResearch.com. info:/
MedicalResearch.com Medical Research Interviews and News
MedicalResearch.com Interview with: Gregory N. Kawchuk Ph.D. Department of Physical Therapy Faculty of Rehabilitation Medicine University of Alberta Edmonton, Alberta, Canada Medical Research: What is the background for this study? What are the main findings? Response: Jerome Fryer, one of … Continue reading →
The post Gas Cavity Produces That Sound When You Crack Your Joints appeared first on MedicalResearch.com Medical Rese........ Read more »
MedicalResearch.com Interview with: Gregory N. Kawchuk Ph.D. (2015) Gas Cavity Produces That Sound When You Crack Your Joints. MedicalResearch.com. info:/
In a mouse model, high-dose injections of alendronate delayed joint damage compared with a low-dose or placebo.... Read more »
Khorasani, M., Diko, S., Hsia, A., Anderson, M., Genetos, D., Haudenschild, D., & Christiansen, B. (2015) Effect of alendronate on post-traumatic osteoarthritis induced by anterior cruciate ligament rupture in mice. Arthritis Research , 17(1). DOI: 10.1186/s13075-015-0546-0
There are osteoarthritic changes in knee as early as one year post anterior cruciate ligament reconstruction in both the tibiofemoral and patellofemoral joints.... Read more »
Culvenor, A., Collins, N., Guermazi, A., Cook, J., Vicenzino, B., Khan, K., Beck, N., van Leeuwen, J., & Crossley, K. (2014) Early knee osteoarthritis is evident one year following anterior cruciate ligament reconstruction: A magnetic resonance imaging evaluation. Arthritis . DOI: 10.1002/art.39005
A new study by researchers from Brigham and Women’s Hospital in Boston, Massachusetts reveals that Asian and Hispanic patients with systemic lupus erythematosus (SLE) have lower mortality rates compared to Black, White, or Native Americans with the disease. Findings published in Arthritis & Rheumatology,a journal of the American College of Rheumatology (ACR), indicate that the risk for death among White patients is much lower than in Black and Native American SLE patients.
Patients with........ Read more »
Gómez-Puerta, J., Barbhaiya, M., Guan, H., Feldman, C., Alarcόn, G., & Costenbader, K. (2014) Racial/Ethnic variation in all-cause mortality among U.S. medicaid recipients with systemic lupus erythematosus: An Hispanic and asian paradox. Arthritis . DOI: 10.1002/art.38981
Following an anterior cruciate ligament (ACL) rupture overall cartilage thickness in the tibiofemoral joint increased at an average of 0.4% per year. Patients under 25 years of age showed greater cartilage thickening than older patients.... Read more »
Eckstein, F., Wirth, W., Lohmander, L., Hudelmaier, M., & Frobell, R. (2014) Five-year follow-up of knee joint cartilage thickness changes after acute anterior cruciate ligament rupture. Arthritis . DOI: 10.1002/art.38881
Cartilage adaption is detectable approximately 2 years follow-up. In this time many changes which occur to the cartilage are a progression of the blunt trauma which the joint is subject to following injury.... Read more »
Van Ginckel A, Verdonk P, & Witvrouw E. (2013) Cartilage adaptation after anterior cruciate ligament injury and reconstruction: implications for clinical management and research? A systematic review of longitudinal MRI studies. Osteoarthritis and Cartilage, 21(8), 1009-24. PMID: 23685095
Take Home Message: Osteoarthritis prevention programs could focus on certain risk factors, such as joint injury, obesity, and occupational activities.
Osteoarthritis (OA), a degenerative joint disease, affects millions of adults worldwide. There are many potential risk factors for OA, including several of interest in sports medicine: obesity, repetitive tasks (physical or occupational activity), and joint injury. It is important to understand what modifiable risk factors may exist so that w........ Read more »
Richmond SA, Fukuchi RK, Ezzat A, Schneider K, Schneider G, & Emery CA. (2013) Are Joint Injury, Sport Activity, Physical Activity, Obesity, or Occupational Activities Predictors for Osteoarthritis? A Systematic Review. The Journal of Orthopaedic and Sports Physical Therapy. PMID: 23756344
Acute knee injuries, including anterior cruciate ligament (ACL) tears, are known to increase an athlete’s risk of developing osteoarthritis (OA). Rate of OA incidence seems to be at an increased risk, despite whether an athlete gets ACL surgery or not. There are various biomechanical as well as biochemical theories as to why this may be. One biochemical theory being that the acute inflammatory process that follows a knee injury propagates OA. Therefore the purpose of this study was to i........ Read more »
Swärd P, Frobell R, Englund M, Roos H, & Struglics A. (2012) Cartilage and bone markers and inflammatory cytokines are increased in synovial fluid in the acute phase of knee injury (hemarthrosis) - a cross-sectional analysis. Osteoarthritis and Cartilage, 20(11), 1302-8. PMID: 22874525
One of the most common reasons to visit a doctor is musculoskeletal pain. And one of the first symptoms of a rheumatological disorder is pain – so it’s great to find this succinct overview of pain in rheumatological disorders. I think one of the saddest findings I’ve read recently (I blogged about it [...]... Read more »
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