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  • January 23, 2015
  • 02:53 PM
  • 1,671 views

First Partially Successful Vaccine Developed Against Prion Disease in Deer

by Pranab Chatterjee in Scepticemia

The first partially successful vaccine against a prion disease (Chronic Wasting Disease in white tailed deer) is good news, but the journey has just begun. ... Read more »

  • January 14, 2015
  • 11:51 AM
  • 817 views

Obesity, Inflammation and the Brain

by William Yates, M.D. in Brain Posts

Brain inflammation produces a variety of emotional, behavior and cognitive symptoms.I remember clearly a patient I cared for with central nervous system lupus erythrematosis (SLE). With SLE flairs she developed flagrant psychotic symptoms including hallucinations requiring inpatient psychiatric care.Between flares she had no significant psychiatric symptoms.Nicole Castanon and two colleagues from France have published a review of the role of obesity-associated inflammation and brain dysfunction......... Read more »

  • January 14, 2015
  • 09:00 AM
  • 1,188 views

Everybody In The Gene Pool - Plants That Swim

by Mark Lasbury in As Many Exceptions As Rules

Plants can be moved by wind and water. Their pollen and seeds can be moved by insects, wind, gravity, but plants themselves don't have motile cells. Well – that’s not always true. Some trees have swimming cells; they take the plunge in order to find a mate.... Read more »

  • January 5, 2015
  • 01:05 AM
  • 656 views

Flag on the Play! Youth Football Players Do Not Know Concussion Signs and Symptoms

by Jane McDevitt in Sports Medicine Research (SMR): In the Lab & In the Field

While 75% of youth football athletes reported that they understood the dangers of concussions over 60% reported that they believe it is okay to continue to play after they sustained a hit to the head that elicited a headache as long as they did not lose consciousness. This suggests that this population needs further concussion education.... Read more »

McAllister-Deitrick, J., Covassin, T., & Gould, D. (2014) Sport-Related Concussion Knowledge Among Youth Football Players. Athletic Training , 6(6), 280-284. DOI: 10.3928/01484834-20141112-03  

  • January 2, 2015
  • 09:38 PM
  • 762 views

The Futility of Progesterone for Traumatic Brain Injury (but hope for the future)

by The Neurocritic in The Neurocritic

Traumatic Brain Injury (TBI) is a serious public health problem that affects about 1.5 million people per year in the US, with direct and indirect medical costs of over $50 billion. Rapid intervention to reduce the risk of death and disability is crucial. The diagnosis and treatment of TBI is an area of active preclinical and clinical research funded by NIH and other federal agencies. But during the White House BRAIN Conference, a leading neurosurgeon painted a pessimistic picture of current tre........ Read more »

Skolnick, B., Maas, A., Narayan, R., van der Hoop, R., MacAllister, T., Ward, J., Nelson, N., & Stocchetti, N. (2014) A Clinical Trial of Progesterone for Severe Traumatic Brain Injury. New England Journal of Medicine, 371(26), 2467-2476. DOI: 10.1056/NEJMoa1411090  

Wright, D., Yeatts, S., Silbergleit, R., Palesch, Y., Hertzberg, V., Frankel, M., Goldstein, F., Caveney, A., Howlett-Smith, H., Bengelink, E.... (2014) Very Early Administration of Progesterone for Acute Traumatic Brain Injury. New England Journal of Medicine, 371(26), 2457-2466. DOI: 10.1056/NEJMoa1404304  

  • December 25, 2014
  • 06:00 PM
  • 905 views

Eliciting Mirth and Laughter via Cortical Stimulation

by The Neurocritic in The Neurocritic

Ho ho ho!“Laughter consists of both motor and emotional aspects. The emotional component, known as mirth, is usually associated with the motor component, namely, bilateral facial movements.”-Yamao et al. (2014)The subject of laughter has been under an increasing amount of scientific scrutiny.  A recent review by Dr. Sophie Scott and colleagues (Scott et al., 2014) emphasized that laughter is a social emotion. During conversations, voluntary laughter by the speaker is a communicative a........ Read more »

LÜDERS, H., LESSER, R., HAHN, J., DINNER, D., MORRIS, H., WYLLIE, E., & GODOY, J. (1991) BASAL TEMPORAL LANGUAGE AREA. Brain, 114(2), 743-754. DOI: 10.1093/brain/114.2.743  

Scott, S., Lavan, N., Chen, S., & McGettigan, C. (2014) The social life of laughter. Trends in Cognitive Sciences, 18(12), 618-620. DOI: 10.1016/j.tics.2014.09.002  

Wild, B., & et al. (2003) Neural correlates of laughter and humour. Brain, 126(10), 2121-2138. DOI: 10.1093/brain/awg226  

Yamao, Y., Matsumoto, R., Kunieda, T., Shibata, S., Shimotake, A., Kikuchi, T., Satow, T., Mikuni, N., Fukuyama, H., Ikeda, A.... (2014) Neural correlates of mirth and laughter: A direct electrical cortical stimulation study. Cortex. DOI: 10.1016/j.cortex.2014.11.008  

  • December 22, 2014
  • 01:05 AM
  • 770 views

Biomarker SNTF May Be The Next New Concussion Diagnosis Tool

by Jane McDevitt in Sports Medicine Research (SMR): In the Lab & In the Field

Biomarkers in the blood, such as SNTF, are elevated for up to 6 days following a concussion compared with preseason levels. This marker may eventually be developed to determine diagnosis and prognosis after a concussion as well as guiding return-to-play decisions.... Read more »

  • December 16, 2014
  • 09:00 AM
  • 1,080 views

Giving, Getting, and Grey Matter

by Mark E. Lasbury in The 'Scope

It’s time to search out Christmas gifts! Let brain research guide you in your giving. We now know why women are often better at picking out gifts, and we know that you expect people to like your homemade gifts more than you should. We have learned that we give gifts to make ourselves feel good, and that too many gifts can screw your kids up for life. But most importantly, it actually is the thought that counts! Merry Christmas.... Read more »

Moll, J., Krueger, F., Zahn, R., Pardini, M., de Oliveira-Souza, R., & Grafman, J. (2006) Human fronto-mesolimbic networks guide decisions about charitable donation. Proceedings of the National Academy of Sciences, 103(42), 15623-15628. DOI: 10.1073/pnas.0604475103  

  • December 9, 2014
  • 09:00 AM
  • 993 views

Winter Gives Me The Shakes

by Mark E. Lasbury in The 'Scope

Your body has several mechanisms to protect you from the cold – and some are just plain weird. You can trap air next to your body just like when your cat hisses and all his fur stands on end. Adults can shiver, but babies can generate heat without shivering. What’s more, adults can learn to act like babies - it will help them stay warm and lose weight!... Read more »

Torkamani, N., Jones, L., Rufaut, N., & Sinclair, R. (2014) Beyond goosebumps: Does the arrector pili muscle have a role in hair loss?. International Journal of Trichology, 6(3), 88. DOI: 10.4103/0974-7753.139077  

Jiménez-Aranda, A., Fernández-Vázquez, G., Campos, D., Tassi, M., Velasco-Perez, L., Tan, D., Reiter, R., & Agil, A. (2013) Melatonin induces browning of inguinal white adipose tissue in Zucker diabetic fatty rats. Journal of Pineal Research. DOI: 10.1111/jpi.12089  

Lim, S., Honek, J., Xue, Y., Seki, T., Cao, Z., Andersson, P., Yang, X., Hosaka, K., & Cao, Y. (2012) Cold-induced activation of brown adipose tissue and adipose angiogenesis in mice. Nature Protocols, 7(3), 606-615. DOI: 10.1038/nprot.2012.013  

Bi, S., & Li, L. (2013) Browning of white adipose tissue: role of hypothalamic signaling. Annals of the New York Academy of Sciences, 1302(1), 30-34. DOI: 10.1111/nyas.12258  

  • December 9, 2014
  • 09:00 AM
  • 963 views

Winter Gives Me The Shakes

by Mark E. Lasbury in The 'Scope

Your body has several mechanisms to protect you from the cold – and some are just plain weird. You can trap air next to your body just like when your cat hisses and all his fur stands on end. Adults can shiver, but babies can generate heat without shivering. What’s more, adults can learn to act like babies - it will help them stay warm and lose weight!... Read more »

Torkamani, N., Jones, L., Rufaut, N., & Sinclair, R. (2014) Beyond goosebumps: Does the arrector pili muscle have a role in hair loss?. International Journal of Trichology, 6(3), 88. DOI: 10.4103/0974-7753.139077  

Jiménez-Aranda, A., Fernández-Vázquez, G., Campos, D., Tassi, M., Velasco-Perez, L., Tan, D., Reiter, R., & Agil, A. (2013) Melatonin induces browning of inguinal white adipose tissue in Zucker diabetic fatty rats. Journal of Pineal Research. DOI: 10.1111/jpi.12089  

Lim, S., Honek, J., Xue, Y., Seki, T., Cao, Z., Andersson, P., Yang, X., Hosaka, K., & Cao, Y. (2012) Cold-induced activation of brown adipose tissue and adipose angiogenesis in mice. Nature Protocols, 7(3), 606-615. DOI: 10.1038/nprot.2012.013  

Bi, S., & Li, L. (2013) Browning of white adipose tissue: role of hypothalamic signaling. Annals of the New York Academy of Sciences, 1302(1), 30-34. DOI: 10.1111/nyas.12258  

  • December 2, 2014
  • 07:55 AM
  • 1,236 views

In Winter, Frozen Isn't Just A Disney Movie

by Mark E. Lasbury in The 'Scope

Everyone knows that you can dies from being out in the cold for too long, but do you how the cold can bring about your demise? It has to do with water, electricity, and believe it or not, stripping.... Read more »

Palmers PJ, Hiltrop N, Ameloot K, Timmermans P, Ferdinande B, Sinnaeve P, Nieuwendijk R, & Malbrain ML. (2014) From therapeutic hypothermia towards targeted temperature management: a decade of evolution. Anaesthesiology intensive therapy. PMID: 25421924  

Argacha, J., Adamopoulos, D., Gujic, M., Fontaine, D., Amyai, N., Berkenboom, G., & van de Borne, P. (2008) Acute Effects of Passive Smoking on Peripheral Vascular Function. Hypertension, 51(6), 1506-1511. DOI: 10.1161/HYPERTENSIONAHA.107.104059  

Adams MD, Earnhardt JT, Dewey WL, & Harris LS. (1976) Vasoconstrictor actions of delta8- and delta9-tetrahydrocannabinol in the rat. The Journal of pharmacology and experimental therapeutics, 196(3), 649-56. PMID: 4606  

  • November 26, 2014
  • 03:35 PM
  • 923 views

Tryptophan vs. The NFL Fan

by Mark Lasbury in The 'Scope

What is tryptophan, and is it indeed responsible for the snoring that follows Thanksgiving dinner? ... Read more »

  • November 19, 2014
  • 01:05 AM
  • 579 views

Are They Really up to the Task or is it Just Sandbagging?

by Kyle Harris in Sports Medicine Research (SMR): In the Lab & In the Field

Among athletes with an invalid computerized neurocognitive test at baseline, 87% received valid scores upon reassessment, which suggests reassessment can be used to gain a valid baseline score.... Read more »

Schatz, P., Kelley, T., Ott, S., Solomon, G., Elbin, R., Higgins, K., & Moser, R. (2014) Utility of Repeated Assessment After Invalid Baseline Neurocognitive Test Performance. Journal of Athletic Training, 49(5), 659-664. DOI: 10.4085/1062-6050-49.3.37  

  • November 18, 2014
  • 01:05 AM
  • 1,027 views

Psychological Strategies Effectively Reduce Perceived and Physiological Markers of Stress

by Caitlin Dios & Bryan Pope in Sports Medicine Research (SMR): In the Lab & In the Field

Both cognitive and somatic relaxation strategies reduce perceived stress and physiological markers of stress.... Read more »

  • November 16, 2014
  • 06:25 AM
  • 904 views

Sleep & Life

by Viputheshwar Sitaraman in Draw Science

Science unveils the role of sleep in life, relationships and music. [Infographic]... Read more »

  • November 12, 2014
  • 09:00 AM
  • 984 views

A Goat For Thanksgiving

by Mark Lasbury in As Many Exceptions As Rules

The cornucopia is a symbol for unending bounty, and has become a synonym for Thanksgiving in the US. But what if we investigate this further; the goat should be the real symbol for Thanksgiving. It spawned the horn of plenty in Greek mythology, it represents a dairy and meat source that the pilgrims made use of. And as far as a sustainable source of red meat, its tops. Goat – the other green meat!... Read more »

Liu YT, Sun J, Luo ZY, Rao SQ, Su YJ, Xu RR, & Yang YJ. (2012) Chemical composition of five wild edible mushrooms collected from Southwest China and their antihyperglycemic and antioxidant activity. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 50(5), 1238-44. PMID: 22300772  

  • November 5, 2014
  • 09:00 AM
  • 1,124 views

Doing More With Less

by Mark Lasbury in As Many Exceptions As Rules

Animal-like protists are similar to animal cells, but they do many things in their single cell that we have a hard time competing with. New research shows that they may be useful in medicine, as well as lethal in some cases. N. fowleri is a brain eating amoeba, but calcium tests of foraminifera may be helpful in bone grafts and repairing skull fractures.... Read more »

Sifuentes LY, Choate BL, Gerba CP, & Bright KR. (2014) The occurrence of Naegleria fowleri in recreational waters in Arizona. Journal of environmental science and health. Part A, Toxic/hazardous substances , 49(11), 1322-30. PMID: 24967566  

  • November 3, 2014
  • 01:05 AM
  • 915 views

See All About It! New Set of Tests to Add to the Concussion Assessment Protocol

by Jane McDevitt in Sports Medicine Research (SMR): In the Lab & In the Field

The vestibular/ocular motor screening (VOMS) is valid assessment to identify young patients with concussions.... Read more »

Mucha A, Collins MW, Elbin RJ, Furman JM, Troutman-Enseki C, DeWolf RM, Marchetti G, & Kontos AP. (2014) A Brief Vestibular/Ocular Motor Screening (VOMS) Assessment to Evaluate Concussions: Preliminary Findings. The American Journal of Sports Medicine, 42(10), 2479-86. PMID: 25106780  

  • October 30, 2014
  • 08:59 AM
  • 902 views

Fright Week: The Stranger in the Mirror

by The Neurocritic in The Neurocritic

In the mirror we see our physical selves as we truly are, even though the image might not live up to what we want, or what we once were. But we recognize the image as “self”. In rare instances, however, this reality breaks down.In Black Swan, Natalie Portman plays Nina Sayers, a ballerina who auditions for the lead in Swan Lake. The role requires her to dance the part of the innocent White Swan (for which she is well-suited), as well as her evil twin the Black Swan — which is initially out........ Read more »

Barnier AJ, Cox RE, Connors M, Langdon R, & Coltheart M. (2011) A stranger in the looking glass: developing and challenging a hypnotic mirrored-self misidentification delusion. The International journal of clinical and experimental hypnosis, 59(1), 1-26. PMID: 21104482  

Chandra SR, & Issac TG. (2014) Mirror image agnosia. Indian journal of psychological medicine, 36(4), 400-3. PMID: 25336773  

Mendez MF, Martin RJ, Smyth KA, & Whitehouse PJ. (1992) Disturbances of person identification in Alzheimer's disease. A retrospective study. The Journal of nervous and mental disease, 180(2), 94-6. PMID: 1737981  

  • October 27, 2014
  • 12:10 PM
  • 887 views

Brain Imaging In Alcoholic Brain Thiamine Deficiency

by William Yates, M.D. in Brain Posts

Chronic consumption of large quantities of alcohol can produce severe deficiency of thiamine (vitamin B1).This can precipitate an acute brain failure known as Wernicke's encephalopathy. Wernicke's encephalopathy is characterized by sudden onset of mental status changes, eye muscle impairment and disturbed gait or ataxia.Other illnesses can also produce this level of severe thiamine deficiency. A partial list of these non-alcoholism causes for thiamine deficiency with encephalopathy includes........ Read more »

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