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  • August 31, 2015
  • 01:05 AM
  • 797 views

Serum Biomarkers May Be Beneficial Concussion Diagnostic/Prognostic Tools

by Jane McDevitt in Sports Medicine Research (SMR): In the Lab & In the Field

A serum biomarker measured on the day of an injury could help diagnose a traumatic brain injury and differentiate mild injuries from more severe injuries.... Read more »

Korley FK, Diaz-Arrastia R, Wu AH, Yue JK, Manley GT M D Ph D, Sair HI, Van Eyk J, Everett AD, Okonkwo DO, Valadka A.... (2015) Circulating Brain Derived Neurotrophic Factor (BDNF) Has Diagnostic and Prognostic Value in Traumatic Brain Injury. Journal of Neurotrauma. PMID: 26159676  

  • August 19, 2015
  • 07:30 AM
  • 1,513 views

Epigenetics And The Evil Twin

by Mark Lasbury in As Many Exceptions As Rules

Monozygotic twins share 100% of their genes. Does this make them identical? Not by a long shot. Epigenetics is the field of study that looks at how environment can change how something looks or works without changing its genes. Is epigenetics responsible for evil twin syndrome in American television?... Read more »

Spannhoff, A., Kim, Y., Raynal, N., Gharibyan, V., Su, M., Zhou, Y., Li, J., Castellano, S., Sbardella, G., Issa, J.... (2011) Histone deacetylase inhibitor activity in royal jelly might facilitate caste switching in bees. EMBO reports, 12(3), 238-243. DOI: 10.1038/embor.2011.9  

Kahn, H., Graff, M., Stein, A., Zybert, P., McKeague, I., & Lumey, L. (2008) A fingerprint characteristic associated with the early prenatal environment. American Journal of Human Biology, 20(1), 59-65. DOI: 10.1002/ajhb.20672  

Zwijnenburg, P., Meijers-Heijboer, H., & Boomsma, D. (2010) Identical but not the same: The value of discordant monozygotic twins in genetic research. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. DOI: 10.1002/ajmg.b.31091  

Thacker, D., Gruber, P., Weinberg, P., & Cohen, M. (2009) Heterotaxy Syndrome with Mirror Image Anomalies in Identical Twins. Congenital Heart Disease, 4(1), 50-53. DOI: 10.1111/j.1747-0803.2008.00229.x  

  • August 19, 2015
  • 01:05 AM
  • 712 views

Should the Focus Be on Limiting Player Contact Instead of Soccer Heading?

by Jane McDevitt in Sports Medicine Research (SMR): In the Lab & In the Field

Banning heading from youth soccer would likely prevent some concussions; however, reducing player-to-player contact may play a more effective role in preventing concussions as well as other injuries.... Read more »

  • August 12, 2015
  • 02:07 PM
  • 843 views

Sometimes a drug is just a specific bit of animal flesh

by Rosin Cerate in Rosin Cerate

Although now obsolete, the use of crudely processed hunks of flesh cut out of dead animals in the treatment of various diseases was widespread in the past. These fleshy parts, usually glands or organs, contain hormones and vitamins necessary for good health that at the time had either not yet been isolated or were difficult/expensive to isolate and use as drugs. They were prepared and administered in several ways: pulverized and snorted, purified somewhat and injected, or cooked up and eaten. Un........ Read more »

DeArmond SJ, & Prusiner SB. (1995) Etiology and pathogenesis of prion diseases. The American Journal of Pathology, 146(4), 785-811. PMID: 7717447  

  • August 12, 2015
  • 09:15 AM
  • 1,586 views

When A Twin Vanishes

by Mark Lasbury in As Many Exceptions As Rules

The things that can happen to twins in the womb before they can be born are bizarre. Some get absorbed by their sibling and some just vanish. Two conjoined twins might grow differently and one may becomes a parasite – one boy just had a second face coming out of his chest that could smile, blink and cry. Even scarier - many of you are harboring a twin right now.... Read more »

Navaei AA, Habibi Z, Moradi E, & Nejat F. (2015) Parasitic rachipagus twins; report of two cases. Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 31(6), 1001-3. PMID: 25715843  

Daga, B., Chaudhary, V., Ingle, A., Dhamangaokar, V., Jadhav, D., & Kulkarni, P. (2009) Double fetus-in-fetu: CT scan diagnosis in an adult. Indian Journal of Radiology and Imaging, 19(3), 216. DOI: 10.4103/0971-3026.54890  

Zahed, L., Oreibi, G., Darwiche, N., & Mitri, F. (2004) Potential trisomy 21 misdiagnosis by amniocentesis due to a resorbed twin. Prenatal Diagnosis, 24(12), 1013-1013. DOI: 10.1002/pd.918  

Lakhoo, K., Ringo, Y., Sillo, T., & Drake, D. (2012) Parasitic twin within spina bifida. African Journal of Paediatric Surgery, 9(3), 240. DOI: 10.4103/0189-6725.104728  

  • July 29, 2015
  • 01:05 AM
  • 713 views

Should You be Nervous about Neural Changes Following ACL Surgery?

by Kyle Harris in Sports Medicine Research (SMR): In the Lab & In the Field

Following anterior cruciate ligament (ACL) surgery, patients have changes in the excitability of pathways that go from the brain (primary motor cortex) and down the spinal cord when compared with an uninjured limb as well as healthy control participants.... Read more »

Pietrosimone, B., Lepley, A., Ericksen, H., Clements, A., Sohn, D., & Gribble, P. (2015) Neural Excitability Alterations After Anterior Cruciate Ligament Reconstruction. Journal of Athletic Training, 50(6), 665-674. DOI: 10.4085/1062-6050-50.1.11  

  • July 27, 2015
  • 01:05 AM
  • 659 views

Accuracy, Affordability, and Portability! Use Your Tablet To Detect Postural Instability

by Jane McDevitt in Sports Medicine Research (SMR): In the Lab & In the Field

Tablet hardware provided accurate data to quantify postural stability within 2.9° of data generated from a force platform system.... Read more »

Alberts, J., Hirsch, J., Koop, M., Schindler, D., Kana, D., Linder, S., Campbell, S., & Thota, A. (2015) Using Accelerometer and Gyroscopic Measures to Quantify Postural Stability. Journal of Athletic Training, 50(6), 578-588. DOI: 10.4085/1062-6050-50.2.01  

  • July 21, 2015
  • 01:29 PM
  • 840 views

Mediterranean Diet and Alzheimer's Disease Prevention

by William Yates, M.D. in Brain Posts

There is an urgent need to identify strategies to prevent or delay the onset of Alzheimer's disease and other forms of dementia.The role of diet as a prevention strategy is controversial. Some research evidence supports a role for a Mediterranean diet in cognitive health and dementia prevention.A recent brain imaging study adds to this evidence. Dr. Lisa Mosconi and colleagues at New York University School of Medicine completed a cross-sectional study of brain magnetic resonance imaging and diet........ Read more »

Mosconi L, Murray J, Tsui WH, Li Y, Davies M, Williams S, Pirraglia E, Spector N, Osorio RS, Glodzik L.... (2014) Mediterranean Diet and Magnetic Resonance Imaging-Assessed Brain Atrophy in Cognitively Normal Individuals at Risk for Alzheimer's Disease. The journal of prevention of Alzheimer's disease, 1(1), 23-32. PMID: 25237654  

  • July 21, 2015
  • 01:05 AM
  • 681 views

Increased Risk of Acute Lower Extremity Injury For Up To a Year Following Concussion

by Jane McDevitt in Sports Medicine Research (SMR): In the Lab & In the Field

College athletes are nearly 2 times more likely to sustain an acute lower extremity injury for up to 1-year post concussion compared with a year before the concussion.... Read more »

  • July 15, 2015
  • 01:32 PM
  • 905 views

Fitness Boosts White Matter Integrity in Aging

by William Yates, M.D. in Brain Posts

Cardiovascular fitness has been correlated with a variety of beneficial effects on brain structure and cognition.These correlations have not proven causality but they do support continued imaging and brain function studies.Scott Hayes from the VA Boston Healthcare System and Boston School of Medicine recently published an information study on this topic.Brain white matter integrity is now open for study using diffusion tensor imaging, available from high-resolution magnetic resonance imaging (MR........ Read more »

Hayes SM, Salat DH, Forman DE, Sperling RA, & Verfaellie M. (2015) Cardiorespiratory fitness is associated with white matter integrity in aging. Annals of clinical and translational neurology, 2(6), 688-98. PMID: 26125043  

  • July 15, 2015
  • 09:25 AM
  • 1,232 views

Ovaries March To A Different Drummer

by Mark Lasbury in As Many Exceptions As Rules

A woman’s right ovary kicks her left ovary’s behind. It puts out more hormones and more pregnancies result from right-sided ovulations than from left-sided ovulations. And there’s none of this right-left stuff you’ve been taught, the ovaries don’t have to take turns ovulating every other month. In fact, a study showed that the best chance for pregnancy is if the ovulation pattern is left-left-right over a three-cycle interval. ... Read more »

Zheng, X., O’Connor, J., Huchzermeyer, F., Wang, X., Wang, Y., Wang, M., & Zhou, Z. (2013) Preservation of ovarian follicles reveals early evolution of avian reproductive behaviour. Nature, 495(7442), 507-511. DOI: 10.1038/nature11985  

  • July 13, 2015
  • 01:31 PM
  • 771 views

Alzheimer's Disease: The Promise of Diabetes Drugs

by William Yates, M.D. in Brain Posts

Current pharmacologic interventions in Alzheimer's disease (AD) have limited effectiveness.Most of the current AD drugs available promise to slow the rate of progression but fail to reverse or prevent the disease.Novel strategies for AD drug treatment are desperately needed and one promising class of agents are the newer drugs for treatment of diabetes. How might a diabetes treatment drug potentially treat a brain disease like AD?A recent review article in World Journal of Diabetes summariz........ Read more »

Candeias EM, Sebastião IC, Cardoso SM, Correia SC, Carvalho CI, Plácido AI, Santos MS, Oliveira CR, Moreira PI, & Duarte AI. (2015) Gut-brain connection: The neuroprotective effects of the anti-diabetic drug liraglutide. World journal of diabetes, 6(6), 807-27. PMID: 26131323  

  • July 10, 2015
  • 10:10 PM
  • 504 views

Type 2 Diabetes Linked to Decreased Brain Blood Flow and Cognitive Ability

by Marie Benz in MedicalResearch.com

MedicalResearch.com Interview with: Vera Novak, MD PhD Associate Professor of Neurology Dept. of Neurology, Stroke Division Director Syncope and Falls in the Elderly Laboratory Beth Israel Deaconess Medical Center Boston, MA MedicalResearch: What is the background for this study? Dr. … Continue reading →
The post Type 2 Diabetes Linked to Decreased Brain Blood Flow and Cognitive Ability appeared first on MedicalResearch.com Medical Research Interviews and News.
... Read more »

Vera Novak, MD PhD. (2015) Type 2 Diabetes Linked to Decreased Brain Blood Flow and Cognitive Ability . MedicalResearch.com. info:/

  • July 8, 2015
  • 01:54 PM
  • 895 views

Brain Imaging and Alzheimer's Disease Prediction

by William Yates, M.D. in Brain Posts

Enhanced early detection of risk for Alzheimer's dementia and other forms of dementia is key to prevention and early intervention.Brain imaging holds promise as a pre-clinical disease risk assessment tool in Alzeimer's dementia.Dementia risk has been linked to several brain imaging abnormalities found with magnetic resonance imaging. These abnormalities have included atrophy of the brain hippocampus, medial temporal lobe as well as white matter hyperintensities.A recent study from France examine........ Read more »

  • July 8, 2015
  • 09:30 AM
  • 1,000 views

What the Heck Are Those Doing There?

by Mark Lasbury in As Many Exceptions As Rules

The neuroendocrine system has lots of exceptions, and this includes the male testes. Just why are they housed outside the main body cavities where they are vulnerable to all sorts of dangers, including your siblings’ kicks? You may think you know, but you probably have only part of the answer. Why is one bigger than the other and why do some animals only have one? ... Read more »

Bogaert, A. (1997) Genital asymmetry in men. Human Reproduction, 12(1), 68-72. DOI: 10.1093/humrep/12.1.68  

  • July 7, 2015
  • 12:16 PM
  • 750 views

Brain Deficits in Visual Hallucinations

by William Yates, M.D. in Brain Posts

One the early things I was taught in my neuroscience training was that new-onset visual hallucinations need to be assessed for medical or "organic causes".Auditory hallucinations were felt to be more characteristic of schizophrenia.One medical disorder linked to visual hallucinations is dementia with Lewy bodies (DLB). DLB is second to Alzheimer's disease in producing neurodegenerative dementia. Visual hallucinations is a hallmark of DLB and is found in up to 70% of clinical samples with th........ Read more »

Heitz C, Noblet V, Cretin B, Philippi N, Kremer L, Stackfleth M, Hubele F, Armspach JP, Namer I, & Blanc F. (2015) Neural correlates of visual hallucinations in dementia with Lewy bodies. Alzheimer's research , 7(1), 6. PMID: 25717349  

  • July 6, 2015
  • 01:05 AM
  • 714 views

Structural Brain Changes Associated to Concussion History and Cognition

by Jane McDevitt in Sports Medicine Research (SMR): In the Lab & In the Field

Prior concussion that resulted in loss of consciousness is a risk factor for decreased hippocampal regions and mild cognitive impairment later in life.... Read more »

  • June 29, 2015
  • 08:55 PM
  • 865 views

You may already be beating cancer

by Angela Reisetter in Steeped in Science

A look at living with disease close at hand, using a couple different papers. Living with Risk.... Read more »

  • June 28, 2015
  • 04:05 AM
  • 1,158 views

Who Will Pay for All the New DBS Implants?

by The Neurocritic in The Neurocritic

Recently, Science and Nature had news features on big BRAIN funding for the development of deep brain stimulation technologies. The ultimate aim of this research is to treat and correct malfunctioning neural circuits in psychiatric and neurological disorders. Both pieces raised ethical issues, focused on device manufacturers and potential military applications, respectively.A different ethical concern, not mentioned in either article, is who will have access to these new devices, and who is goin........ Read more »

  • June 25, 2015
  • 06:36 PM
  • 379 views

Consciousness May Arise Unconsciously

by Marie Benz in MedicalResearch.com

MedicalResearch.com Interview with: Ezequiel Morsella, Ph.D. Associate Professor of Neuroscience Department of Psychology San Francisco State University Assistant Adjunct Professor Department of Neurology University of California, San Francisco Boardmember, Scientific Advisory Board Institute of Cognitive Neurology (INECO), Buenos Aires Medical … Continue reading →
The post Consciousness May Arise Unconsciously appeared first on MedicalResearch.com Medical Research Interviews and New........ Read more »

Ezequiel Morsella, Ph.D., Associate Professor of Neuroscience, & Department of Psychology San Francisco State Uni. (2015) Consciousness May Arise Unconsciously . MedicalResearch.com. info:/

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