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  • November 21, 2016
  • 11:10 AM
  • 395 views

Benefits of Physical Activity in Parkison's Disease

by William Yates, M.D. in Brain Posts

Parkinson's disease (PD) is a progressive neurodegerative disorder estimated to affect 7 to 10 million individual worldwide.The primary mechanism for Parkinson's disease is a reduction in the neurotransmitter dopamine in the midbrain region of the substantia nigra highlighted in red in the figure.PD impairs motor and cognitive functions and leads to significant decline in psychosocial functioning.Drugs for PD can be effective in reversing and slowing the progression of the illness. However, resp........ Read more »

Lauzé M, Daneault JF, & Duval C. (2016) The Effects of Physical Activity in Parkinson's Disease: A Review. Journal of Parkinson's disease, 6(4), 685-698. PMID: 27567884  

  • November 2, 2016
  • 11:09 AM
  • 379 views

Weight Training Boosts Brain Size and Performance

by William Yates, M.D. in Brain Posts

Aerobic exercise increases brain blood flow and has demonstrated beneficial effects on cognition.The effects of weight training exercise on the brain is less frequently studied. Hence, we know little about the effect and mechanism of weight training on brain function and performance.A recent study provides some needed insight on this topic.A study by C Suo and colleagues from Australia examined the effects of resistance training and cognitive skills training on brain structure and function.The k........ Read more »

Suo C, Singh MF, Gates N, Wen W, Sachdev P, Brodaty H, Saigal N, Wilson GC, Meiklejohn J, Singh N.... (2016) Therapeutically relevant structural and functional mechanisms triggered by physical and cognitive exercise. Molecular psychiatry, 21(11), 1645. PMID: 27090304  

  • September 19, 2016
  • 11:11 AM
  • 426 views

Preventing Depression Following Brain Injury

by William Yates, M.D. in Brain Posts

Depression is a common feature following traumatic brain injury (TBI). Post-TBI depression may be difficult to treat and evolve into a chronic depression syndrome.A recent published study demonstrates that prophylactic SSRI antidepressant treatment may reduce the incidence of depression following TBI.This study was conducted by investigators affiliated with Baylor College of Medicine and the Department of Psychiatry at the University of Iowa.Ninety four subjects were recruited to this randomized........ Read more »

  • August 30, 2016
  • 11:59 AM
  • 485 views

Dyslexia Improvement in Medication Trial

by William Yates, M.D. in Brain Posts

Dyslexia or developmental reading disorder is a common learning disorder affecting about 5% of the school age population.Treatment of dyslexia is difficult and typically is focused on special education classes and reading exercises.Medication treatment for dyslexia is nearly unheard of as no FDA-approved drug is available for the condition.However, a recent randomized clinical drug trial found evidence to support the potential use of atomoxetine for dyslexia.Atomoxetine is a drug approved for at........ Read more »

  • August 25, 2016
  • 09:40 AM
  • 597 views

How to rebuild a brain

by gdw in FictionalFieldwork

After the stroke The human brain is complicated. Very complicated. And like any piece of complex machinery that relies on the smooth functioning of many components, it’s not immune to malfunction. When a part of the brain doesn’t get proper nutrition through a nice and smooth blood flow, things go awry and a stroke occurs. […]... Read more »

  • May 21, 2016
  • 10:21 AM
  • 587 views

Quick Aspirin Use Reduces Stroke Risk in TIA

by William Yates, M.D. in Brain Posts

A free full-text commentary in the Lancet summarizes recent evidence of the benefit of aspirin in stroke prevention.This commentary focused on what is called secondary prevention. Secondary prevention is defined as prevention following events related to the disease in question.So secondary prevention in stroke would be reduction in stroke risk in those who have had a stroke or pre-stroke syndromes such as transient ischemic attacks (TIA).The key take-home message from the commentary by Graeme Ha........ Read more »

  • May 3, 2016
  • 11:36 AM
  • 347 views

Delirium and Aortic Valve Surgery Outcome

by William Yates, M.D. in Brain Posts

Delirium is an acute confusional state that is common in elderly hospitalized patients.I think of it light a sign of acute brain failure requiring aggressive attentional for detection and treatment of any reversible underlying causes.Delirium in elderly hospitalized patients is a marker for poor outcome in a variety of medical and surgical subjects.A recent study published by a Norwegian team found effects on outcome for delirium following surgical aortic valve replacement. The key findings from........ Read more »

Eide LS, Ranhoff AH, Fridlund B, Haaverstad R, Hufthammer KO, Kuiper KK, Nordrehaug JE, Norekvål TM, & Delirium in Octogenarians Undergoing Cardiac Surgery or Intervention-CARDELIR Investigators. (2016) Delirium as a Predictor of Physical and Cognitive Function in Individuals Aged 80 and Older After Transcatheter Aortic Valve Implantation or Surgical Aortic Valve Replacement. Journal of the American Geriatrics Society. PMID: 27106745  

  • January 24, 2016
  • 02:45 PM
  • 715 views

Treat the pain... or treat the depression? Carpal Tunnel Syndrome management

by Bronwyn Thompson in Healthskills: Skills for Healthy Living

Carpal tunnel syndrome is a very common pain disorder associated with compression of the median nerve at the carpal tunnel. Approximately 139 women and 67 males per 100,000 people will report this problem over the course of one year, although this depends on the definition used. The problem with CTS is not only that it is common, but also that it affects function - it is really difficult to carry out normal daily life with a numb or tingly hand, poor grip strength (particularly in the fingertips........ Read more »

Fernández-Muñoz, J., Palacios-Ceña, M., Cigarán-Méndez, M., Ortega-Santiago, R., de-la-Llave-Rincón, A., Salom-Moreno, J., & Fernández-de-las-Peñas, C. (2016) Pain is Associated to Clinical, Psychological, Physical, and Neurophysiological Variables in Women With Carpal Tunnel Syndrome. The Clinical Journal of Pain, 32(2), 122-129. DOI: 10.1097/AJP.0000000000000241  

  • January 20, 2016
  • 05:44 PM
  • 515 views

Parkinson’s Disease: No Benefit from Physical Therapy in Mild to Moderate Disease

by Marie Benz in MedicalResearch.com

More Interviews on Neurological Disorders on MedicalResearch.com MedicalResearch.com Interview with: Professor Carl E Clarke Professor of Clinical Neurology and Honorary Consultant Neurologist Department of Neurology City Hospital Sandwell and West Birmingham Hospitals NHS Trust Birmingham UK  Medical Research: What is the background … Continue reading →
The post Parkinson’s Disease: No Benefit from Physical Therapy in Mild to Moderate Disease appeared first on MedicalResear........ Read more »

Professor Carl E Clarke. (2016) Parkinson's Disease: No Benefit from Physical Therapy in Mild to Moderate Disease. MedicalResearch.com. info:/

  • November 18, 2015
  • 01:00 PM
  • 879 views

Predictors of Poor Outcome After Traumatic Brain Injury

by William Yates, M.D. in Brain Posts

The outcome following traumatic brain injury (TBI) is often unpredictable and variable.Two individuals with similar types of TBI can have quite different outcomes ranging from total disability to functional employment.Torun Finnanger and colleagues from Norway and Australia recently reported on a study that examined a number of predictor variables on self-reported outcome following TBI.In this study, 67 adolescents and adults with moderate to severe TBI completed baseline assessments and were fo........ Read more »

  • October 30, 2015
  • 11:06 AM
  • 984 views

Wii Fit Games for Children with Coordination Problems

by William Yates, M.D. in Brain Posts

Among the types of development problems of childhood is developmental coordination disorder or DCD.In DCD, children show delay and subnormal performance in coordinated motor skills.This may be noted as a general tendency of clumsiness with difficulties in activities such as catching a ball, using scissors, handwriting or riding a bike.Computer games such as the Nintendo Wii platform provide a method to improve a variety of motor and coordination skills in a fun environment.A South African team r........ Read more »

  • October 12, 2015
  • 11:29 AM
  • 751 views

Neuroplasticity and Training the Older Brain

by William Yates, M.D. in Brain Posts

Neuroplasticity is the brain and nervous systems ability to evolve and to repair deficits.At a basic level it represents the ability to learn and develop a structural and functional system to interact with the environment.The brain's neuroplasticity is maximized during childhood and adolescence. This adaptability wanes with age. However, some neuroplasticity ability persists in the older brain.This persistence was highlighted in a study from Hong Kong recently published in the journal Neural Pla........ Read more »

Leung NT, Tam HM, Chu LW, Kwok TC, Chan F, Lam LC, Woo J, & Lee TM. (2015) Neural Plastic Effects of Cognitive Training on Aging Brain. Neural plasticity, 535618. PMID: 26417460  

  • September 29, 2015
  • 11:04 AM
  • 615 views

Cognitive Enhancers in Neuroscience Medicine

by William Yates, M.D. in Brain Posts

Neuropsychiatric disorders cause impairment via multiple pathways. One pathway to impairment is cognitive impairment via attention problems, cognitive slowing and memory disruption.Barbara Sahakian and colleagues recently published an interesting manuscript examining the issue of cognitive enhancement.Their review begins by summarizing some of the research related to cognitive enhancement in four neuropsychiatric syndromes. I will summarize their main points by specific disorder.Alzheimer's Dise........ Read more »

Sahakian BJ, Bruhl AB, Cook J, Killikelly C, Savulich G, Piercy T, Hafizi S, Perez J, Fernandez-Egea E, Suckling J.... (2015) The impact of neuroscience on society: cognitive enhancement in neuropsychiatric disorders and in healthy people. Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 370(1677). PMID: 26240429  

  • June 30, 2015
  • 02:59 PM
  • 446 views

Both Young and Old Lose Muscle Strength After Short Term Inactivity

by Marie Benz in MedicalResearch.com

MedicalResearch.com Interview with: Andreas Vigelsø PhD, research assistant University of Copenhagen Faculty of Health Sciences Center for Healthy Aging Dept. of Biomedical Sciences Copenhagen Denmark Medical Research: What is the background for this study? Response: According to the UN, the … Continue reading →
The post Both Young and Old Lose Muscle Strength After Short Term Inactivity appeared first on MedicalResearch.com Medical Research Interviews and News.
... Read more »

Andreas Vigelsø PhD, research assistant, & University of Copenhagen. (2015) Both Young and Old Lose Muscle Strength After Short Term Inactivity. MedicalResearch.com. info:/

  • March 15, 2015
  • 03:11 PM
  • 573 views

Tai Chi Based Cardiac Rehabilitation Improved Functional Capacity After Heart Attack

by Marie Benz in MedicalResearch.com

MedicalResearch.com Medical Research Interviews and News
MedicalResearch.com Interview with: Ricardo Stein, MD, ScD Exercise Cardiology Research Group, Cardiology Division Federal University of Rio Grande do Sul, Hospital de Clinicas de Porto Alegre, Porto Alegre, RS, Brazil MedicalResearch: What is the background for this study? Dr. Stein: … Continue reading →
The post Tai Chi Based Cardiac Rehabilitation Improved Functional Capacity After Heart Attack appeared first on MedicalResea........ Read more »

MedicalResearch.com Interview with:, & Ricardo Stein, MD, ScD. (2015) Tai Chi Based Cardiac Rehabilitation Improved Functional Capacity After Heart Attack. MedicalResearch.com. info:/

  • February 2, 2015
  • 11:39 AM
  • 836 views

Exercise in the Prevention of Alzheimer's Disease

by William Yates, M.D. in Brain Posts

Growing evidence links physical activity to improved cognitive outcome in elderly individuals.Few studies have examined effects of exercise on those at highest risk for Alzheimer's disease.J Carson Smith and colleagues recently published a prospective study of a cohort of older adults using structural magnetic resonance imaging.The key elements of the design of their study included the following elements:Participants: 97 adults between the ages of 65 and 89Physical activity level: Frequency and ........ Read more »

Smith JC, Nielson KA, Woodard JL, Seidenberg M, Durgerian S, Hazlett KE, Figueroa CM, Kandah CC, Kay CD, Matthews MA.... (2014) Physical activity reduces hippocampal atrophy in elders at genetic risk for Alzheimer's disease. Frontiers in aging neuroscience, 61. PMID: 24795624  

  • December 22, 2014
  • 12:35 PM
  • 1,031 views

Mind-Controlled Prosthetics

by Viputheshwar Sitaraman in Draw Science

Researchers at JHU have demonstrated a prosthetic arm that is controlled completely by the user's thoughts. [Infographic]... Read more »

Collinger, J., Wodlinger, B., Downey, J., Wang, W., Tyler-Kabara, E., Weber, D., McMorland, A., Velliste, M., Boninger, M., & Schwartz, A. (2013) High-performance neuroprosthetic control by an individual with tetraplegia. The Lancet, 381(9866), 557-564. DOI: 10.1016/S0140-6736(12)61816-9  

  • December 13, 2014
  • 11:56 AM
  • 1,147 views

Animal Research Sheds Light on Harmful Mood Disorders in New Mothers

by Wiley Asia Blog in Wiley Asia Blog - Social Science

In the days shortly after giving birth, most mothers experience a period of increased calmness and decreased stress responses, but around 20% of mothers experience anxiety. Some women may become depressed, and around one in a thousand can develop psychosis. The latest evidence indicates that these distressing responses to motherhood are still poorly understood, but that animal research could provide valuable clues to their causes.

Writing in the British Journal of Pharmacology, Dr David Slatt........ Read more »

Perani, C., & Slattery, D. (2014) Using animal models to study post-partum psychiatric disorders. British Journal of Pharmacology, 171(20), 4539-4555. DOI: 10.1111/bph.12640  

  • October 30, 2014
  • 11:20 AM
  • 973 views

Alcoholism as a Reward System Dysfunction

by William Yates, M.D. in Brain Posts

Alcoholism and other addictive behaviors often occur together within individual patients.For example, individuals with alcoholism commonly also are smokers and meet criteria for a diagnosis of nicotine dependence.This co-occurrence suggests multiple types of addiction may share genetic and environmental risk factors. Additionally, there might be a common neurobiological mechanism in play for many addictions.Kenneth Blum and other leading alcoholism researchers recently published a review that pr........ Read more »

  • October 23, 2014
  • 10:20 AM
  • 908 views

Smartphone App Boosts Alcoholism Treatment Outcome

by William Yates, M.D. in Brain Posts

Smartphone apps and other mobile technology are emerging as promising tools in medical treatment.A recent randomized study published in JAMA Psychiatry found evidence that a smartphone app improves alcoholism treatment outcomes.David Gustafson and colleagues conducted a study funded by the National Institute of Alcohol Abuse and Alcoholism.A series of 349 adults with DSM-IV alcohol dependence were enrolled as they entered a alcoholism residential treatment program.Approximately half of the subje........ Read more »

Gustafson DH, McTavish FM, Chih MY, Atwood AK, Johnson RA, Boyle MG, Levy MS, Driscoll H, Chisholm SM, Dillenburg L.... (2014) A smartphone application to support recovery from alcoholism: a randomized clinical trial. JAMA psychiatry, 71(5), 566-72. PMID: 24671165  

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