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  • October 15, 2009
  • 10:07 AM

Risk taking and audacity in science…

by Jim Caryl in mental indigestion

In the October edition of Cell1 [sorry, behind an academic wall], Amy Maxmen, a New York based science writer, discusses how tackling long-standing scientific problems (i.e. studies that have been prone to failure), or refuting dogma, are perceived to be a poor strategy for early-career researchers; and contends that perhaps they shouldn’t be.
A common [...]... Read more »

  • September 26, 2009
  • 09:38 PM

Scientists: glorified bureaucrats?

by Psi Wavefunction in Skeptic Wonder

I found this a while ago, but no one, to my knowledge, seems to have blogged about it:Real Lives and White Lies in the Funding of Scientific ResearchThe granting system turns young scientists into bureaucrats and then betrays themLawrence PA (2009) PLoS Biology 7(9): e1000197 (open access)Go read the article. It's scary. And seems accurate enough even to an undergrad with limited experience. (Shit, I've been jaded already before even going to grad school...)Within the article is thi........ Read more »

  • September 12, 2009
  • 07:55 PM

The Cost and Duration of Drug Discovery Must Decrease

by Michael Long in Phased

Ray Dorsey (University of Rochester, New York) and coworkers have shown that biomedical scientists are not making optimal use of the money they receive for research. This news feature was written on September 12, 2009.... Read more »

Dorsey, E. R., Thompson, J. P., Carrasco, M., de Roulet, J., Vitticore, P., Nicholson, S., Johnston, S. C., Holloway, R. G, & Moses III, H. (2009) Financing of U.S. Biomedical Research and New Drug Approvals across Therapeutic Areas. PLoS ONE, 4(9). DOI: 10.1371/journal.pone.0007015  

  • September 10, 2009
  • 10:28 AM

Why don’t scientists share data?

by Duncan Hull in O'Really?

As Vince Smith once put it [1] data are the fuel of Science:
“The fabric of science is changing, driven by a revolution in digital technologies that facilitate the acquisition and communication of massive amounts of data. This is changing the nature of collaboration and expanding opportunities to participate in science. If digital technologies are the [...]... Read more »

Schofield, P., Bubela, T., Weaver, T., Portilla, L., Brown, S., Hancock, J., Einhorn, D., Tocchini-Valentini, G., Hrabe de Angelis, M., & Rosenthal, N. (2009) Post-publication sharing of data and tools. Nature, 461(7261), 171-173. DOI: 10.1038/461171a  

Toronto International Data Release Workshop Authors. (2009) Prepublication data sharing. Nature, 461(7261), 168-170. DOI: 10.1038/461168a  

Bryn Nelson. (2009) Data sharing: Empty archives. Nature, 461(7261), 160-163. DOI: 10.1038/461160a  

  • July 12, 2009
  • 07:16 PM

A Tear In The Consciousness: Irony, Secrecy and Dissimulation

by Mike Innes in The Complex Terrain Laboratory

The latest issue of Harper's includes a tongue-in-cheek proposal for a study of "weaponized irony" (not, not iron-working; the "it's ironical" kind of irony), and development of a sort of semantic mapping technology, the "Ironic Cloud". There's a thick literature on the subject of psychosocial compartmentation, though, and it speaks directly to the ideas in the proposal. ... Read more »

  • June 19, 2009
  • 04:27 AM

Lies, damned lies, and scientific misconduct

by Jacob Aron in Just A Theory

“Science is inevitably biased to some extent,” says Dr Daniele Fanelli, “because it’s made by human beings.” One might easily dismiss this claim as unfounded, but Fanelli has the numbers to back it up. His recent research paper combined over 20 previous studies on scientific misconduct, and found that nearly 2% of scientists admit to [...]... Read more »

  • May 16, 2009
  • 07:02 PM

One Third of the Clinical Cancer Studies Report Conflict of Interest

by Laika in Laika's Medliblog

While many of us just recovered from the news that Elsevier was paid to produce fake Journals to promote pharmaceutical products, another news item has appeared about “conflicts of interests in scientific publications”

This news is based on a new journal article from researchers from the University of Michigan’s Comprehensive Cancer Center in Ann Arbor, published [...]... Read more »

  • April 7, 2009
  • 12:56 PM

Combating Obesity with the Anti-Munchies: Are CB1 Inhibitors Any Good?

by Laura E. Mariani in Neurotypical?

In a nice bit of synchronicity, I just found a study by Dr. John McPartland in PLoS ONE examining conflicts of interest in academic medicine with respect to the cannabinoid (CB1) recentor antagonist, rimonabant (aka Acomplia). We actually discussed this drug in my Cellular and Developmental Neuroscience class this morning, as we've been learning about long-term potentiation, long-term depression, and other forms of synaptic plasticity that can be mediated by endogenous cannabinoids. I've also be........ Read more »

  • October 14, 2008
  • 06:38 AM

Happy Open Access Day !

by CxLxMx in cxlxmxrx

Today, October 14, is the first Open Access Day--a day devoted to broadening awareness and understanding of free and available information. Open Access Day is a joint venture of the Public Library of Science (PLoS), the Scholarly Publishing and Academic Resources Coalition and Students for Free Culture. In response to the call for synchroblogging, I've decided to direct some attention to the issue of open access in nursing.Although nursing research is promoted in BSN programs and as an ingredi........ Read more »

Don E. Detmer, Meryl Bloomrosen, Brian Raymond, & Paul Tang. (2008) Integrated personal health records: Transformative tools for consumer-centric care. BMC Medical Informatics and Decision Making, 8(1), 45. DOI: 10.1186/1472-6947-8-45  

Carole A Estabrooks, Shannon Scott, Janet E Squires, Bonnie Stevens, Linda O'Brien-Pallas, Judy Watt-Watson, Joanne Profetto-McGrath, Kathy McGilton, Karen Golden-Biddle, Janice Lander.... (2008) Patterns of research utilization on patient care units. Implementation Science, 3(1), 31. DOI: 10.1186/1748-5908-3-31  

Casida, J, & Pinto-Zipp, G. (2008) Leadership-Organizational Culture relationship in nursing units of acute care hospitals. Nursing Economic$, 26(1), 7-13.

  • November 30, -1
  • 12:00 AM

...How to Fix Science

by Viputheshwar Sitaraman in Draw Science

(Part 2/2) However, we can fix science. [Infographic]... Read more »

Alberts, B., Kirschner, M., Tilghman, S., & Varmus, H. (2014) Rescuing US biomedical research from its systemic flaws. Proceedings of the National Academy of Sciences, 111(16), 5773-5777. DOI: 10.1073/pnas.1404402111  

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