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  • August 24, 2016
  • 04:05 AM
  • 689 views

Keeping Your “Ion” The Ball – Salts and Life

by Mark Lasbury in As Many Exceptions As Rules

Lost at sea is no way to go to your everlasting reward. Sit in the sunshine too long and you lose your salts and all your functions go bonkers. Drink seawater and you end up with too much sodium and potassium and go nuts. Either way your dead, and it all has to do with your body’s tipping point and the kidney’s function in maintaining an osmotic potential. What is weirder - licorice can cause just about the same problem. ... Read more »

Räikkönen, K., Seckl, J., Heinonen, K., Pyhälä, R., Feldt, K., Jones, A., Pesonen, A., Phillips, D., Lahti, J., Järvenpää, A.... (2010) Maternal prenatal licorice consumption alters hypothalamic–pituitary–adrenocortical axis function in children. Psychoneuroendocrinology, 35(10), 1587-1593. DOI: 10.1016/j.psyneuen.2010.04.010  

  • August 3, 2016
  • 10:13 AM
  • 1,003 views

Do we need a doping Olympics? The ethics of doping in sports

by gdw in FictionalFieldwork

There is only her and the track. The people standing on her left and right do not matter now. She has only one adversary: time. In her head she plays how the future might…will unfold. Forty seven strides. That’s all she needs. All things on the periphery disappear. Her world, her universe becomes a single […]... Read more »

  • June 12, 2016
  • 11:35 PM
  • 1,029 views

Seeing Through the Skin

by Aurametrix team in Olfactics and Diagnostics

​Human skin emits light (albeit the glow is extremely weak) and a wide variety of small molecules that may be sometimes "sniffed" by dogs or even other humans. These chemicals tell a story about our health and wellness, things we eat and drink, touch and breathe. Mosquitoes use such emissions to assess our "attractiveness" from indicators such as Indoles (unpleasantly smelling but healthy "inner soil" biomarker) or carbon dioxide (amount of which correlates with the size of the person........ Read more »

Gao W, Emaminejad S, Nyein HY, Challa S, Chen K, Peck A, Fahad HM, Ota H, Shiraki H, Kiriya D.... (2016) Fully integrated wearable sensor arrays for multiplexed in situ perspiration analysis. Nature, 529(7587), 509-14. PMID: 26819044  

Yokota T, Zalar P, Kaltenbrunner M, Jinno H, Matsuhisa N, Kitanosako H, Tachibana Y, Yukita W, Koizumi M, & Someya T. (2016) Ultraflexible organic photonic skin. Science advances, 2(4). PMID: 27152354  

  • June 6, 2016
  • 11:34 AM
  • 946 views

Burning seaweed to make glass and avoid a lumpy neck

by Rosin Cerate in Rosin Cerate

Seaweed is one of those tricky biological groups, as membership isn't just about being a close relative. It typically includes plant-like organisms found among several types of algae - green, brown, and red - and depending on who you're talking to also includes masses of cyanobacteria (which are distant relatives of algae). Functionally, all seaweeds enjoy growing in salty water and use the sun to manufacture sugary meals for themselves. Their need for sun means they are found in sunlit coastal ........ Read more »

  • May 3, 2016
  • 01:00 PM
  • 557 views

"The Biggest Loser": Long-term Effects

by William Yates, M.D. in Brain Posts

Yesterday I posted a link to a New York Times article that posted a summary outcome in fourteen participants in TV's "The Biggest Loser" show.The study found a trend towards post-show weight gain for 13/14 of the participants.Four participants actually gained so much weight that after six years they weighed more than before participating in the show.A key finding from the study was this weight gain could be explained by a metabolic response resulting in up to 800 calories less burned daily ........ Read more »

Fothergill, E., Guo, J., Howard, L., Kerns, J., Knuth, N., Brychta, R., Chen, K., Skarulis, M., Walter, M., Walter, P.... (2016) Persistent metabolic adaptation 6 years after “The Biggest Loser” competition. Obesity. DOI: 10.1002/oby.21538  

  • April 14, 2016
  • 08:50 AM
  • 1,041 views

Tales from the pharmaceutical minor leagues

by Rosin Cerate in Rosin Cerate

When a drug company first gets its hands on a potential new drug, it will usually assign it a code name. Later on, as the drug works its way through trials designed to make sure it does something useful (e.g. reduce blood pressure) without causing serious harm (e.g. liver failure), it's given a catchier moniker like fluoxetine or atorvastatin. If the trials are a success, and the government is happy with how they were carried out, the drug can be brought to market. Most drugs don't make it. A go........ Read more »

  • January 22, 2016
  • 12:25 PM
  • 474 views

Thyroid Gland’s Importance Recognized During Thyroid Awareness Month

by Marie Benz in MedicalResearch.com

MedicalResearch.com Interview with: Marita Teng, MD Associate Professor of Otolaryngology Head and Neck Institute Icahn School of Medicine at Mount Sinai MedicalResearch.com Editor’s note: January is Thyroid Awareness Month. In recognition, Dr. Teng discusses the thyroid gland’s important role in the … Continue reading →
The post Thyroid Gland’s Importance Recognized During Thyroid Awareness Month appeared first on MedicalResearch.com.
... Read more »

Marita Teng, MD. (2016) Thyroid Gland's Importance Recognized During Thyroid Awareness Month. MedicalResearch.com. info:/

  • January 15, 2016
  • 05:38 PM
  • 569 views

Metformin May Inhibit Progression of Pancreatic Cancer In Obese Patients

by Marie Benz in MedicalResearch.com

More on Pancreatic Cancer on MedicalResearch.com MedicalResearch.com Interview with: Dai Fukumura, M.D., Ph.D. Joao Incio, M.D. and Rakesh K. Jain, Ph.D Edwin L. Steele Laboratory Department of Radiation Oncology Massachusetts General Hospital Harvard Medical School Medical Research: What is the … Continue reading →
The post Metformin May Inhibit Progression of Pancreatic Cancer In Obese Patients appeared first on MedicalResearch.com.
... Read more »

Dai Fukumura, M.D., Ph.D. (2016) Metformin May Inhibit Progression of Pancreatic Cancer In Obese Patients. MedicalResearch.com. info:/

  • December 27, 2015
  • 09:10 AM
  • 493 views

Polycystic Ovary Syndrome Linked To Multiple Skin Findings

by Marie Benz in MedicalResearch.com

MedicalResearch.com Interview with: Kanade Shinkai, MD PhD Associate Professor of Clinical Dermatology Director, Residency Program Endowed Chair in Dermatology Medical Student Education UCSF Department of Dermatology San Francisco, CA 94115  Medical Research: What is the background for this study? What … Continue reading →
The post Polycystic Ovary Syndrome Linked To Multiple Skin Findings appeared first on MedicalResearch.com.
... Read more »

Kanade Shinkai, MD PhD. (2015) Cutaneous Findings and Systemic Associations in Women With Polycystic Ovary Syndrome . MedicalResearch.com. info:/

  • December 23, 2015
  • 02:30 PM
  • 604 views

HbA1c May Be Useful Screening Test For Pregnant Women With Unrecognized Diabetes

by Marie Benz in MedicalResearch.com

MedicalResearch.com Interview with: Dr. Janet Rowan Obstetric Physician National Women’s Health, Auckland Medical Research: What is the background for this study? Dr. Rowan: Clinicians are interested in screening during early pregnancy to identify women with previously unrecognised diabetes, as these … Continue reading →
The post HbA1c May Be Useful Screening Test For Pregnant Women With Unrecognized Diabetes appeared first on MedicalResearch.com.
... Read more »

Dr. Janet Rowan. (2015) HbA1c May Be Useful Screening Test For Pregnant Women With Unrecognized Diabetes. MedicalResearch.com. info:/

  • December 21, 2015
  • 06:43 PM
  • 505 views

Parathyroidectomy Superior To Medications For Hypercalcemia in Transplant Patients

by Marie Benz in MedicalResearch.com

MedicalResearch.com Interview with: Josep M Cruzado, MD Head, Nephrology Department Hospital Universitari de Bellvitge  Medical Research: What is the background for this study? What are the main findings? Dr. Cruzado: Tertiary hyperparathyroidism is frequent after renal transplantation. Inappropriately high parathyroid … Continue reading →
The post Parathyroidectomy Superior To Medications For Hypercalcemia in Transplant Patients appeared first on MedicalResearch.com.
... Read more »

Josep M Cruzado, MD. (2015) Parathyroidectomy Superior To Medications For Hypercalcemia in Transplant Patients. MedicalResearch.com. info:/

  • December 14, 2015
  • 05:28 PM
  • 1,071 views

Enzymes we use at home

by Rosin Cerate in Rosin Cerate

Enzymes are life's little way of taking shortcuts, speeding up chemical reactions to permit the diverse and intricate metabolic pathways by which living organisms do what they do. In addition to being filled with enzymes helping to ensure our bodies work properly, we've figured out ways to produce bucketloads of them on their own to help speed along various tasks.By sticking genes into bacteria, fungi, or cells from a hamster's ovaries, we can give them specialized instructions on how to ma........ Read more »

  • November 27, 2015
  • 09:06 AM
  • 564 views

Personalized Diabetes Management Effective For Women But Not Men

by Marie Benz in MedicalResearch.com

MedicalResearch.com Interview with: Marlene Øhrberg Krag , MD, MIH Department of Public Health University of Copenhagen, Denmark Medical Research: What is the background for this study? Dr. Krag: In this follow-up study we wanted to assess whether there was any difference in longterm … Continue reading →
The post Personalized Diabetes Management Effective For Women But Not Men appeared first on MedicalResearch.com.
... Read more »

Marlene Øhrberg Krag , MD, MIH. (2015) Personalized Diabetes Management Effective For Women But Not Men. MedicalResearch.com. info:/

  • November 24, 2015
  • 04:51 PM
  • 524 views

Walnuts Improve Diet, Cardiometabolic Health in Patients At Risk of Diabetes

by Marie Benz in MedicalResearch.com

MedicalResearch.com Interview with: David L. Katz, MD, MPH, FACPM, FACP, FACLM Director, Yale University Prevention Research Center Griffin Hospital President, American College of Lifestyle Medicine Founder, True Health Initiative Medical Research: What is the background for this study? What are the main findings? … Continue reading →
The post Walnuts Improve Diet, Cardiometabolic Health in Patients At Risk of Diabetes appeared first on MedicalResearch.com.
... Read more »

David L. Katz, MD,. (2015) Walnuts Improve Diet, Cardiometabolic Health in Patients At Risk of Diabetes. MedicalResearch.com. info:/

  • November 18, 2015
  • 01:22 PM
  • 1,230 views

Early wrong ideas about how our glands work

by Rosin Cerate in Rosin Cerate

Let's talk about glands! These highly specialized bits of tissue put together and pump out useful compounds to ensure we stay healthy and can do the things animals do (aim to reproduce, mostly). Exocrine glands release fluids such as sweat, saliva, milk, tears, mucous, and bile into segments of our digestive tract or onto the surface of our skin (and eyes). Endocrine glands toss hormones and other regulatory molecules into our bloodstream, to be carried to distant locales bearing instructions to........ Read more »

López-Muñoz F, Molina J, Rubio G, & Alamo C. (2011) An historical view of the pineal gland and mental disorders. Journal of Clinical Neuroscience, 18(8), 1028-1037. DOI: 10.1016/j.jocn.2010.11.037  

  • October 22, 2015
  • 02:46 PM
  • 474 views

Gene Therapy with Leptin Induces Weight Loss

by Marie Benz in MedicalResearch.com

MedicalResearch.com Interview with: Urszula T. Iwaniec, Ph.D. Associate Professor Skeletal Biology Laboratory School of Biological and Population Health Sciences Oregon State University Corvallis, OR 97331 Medical Research: What is the background for this study? What are the main findings? Dr. … Continue reading →
The post Gene Therapy with Leptin Induces Weight Loss appeared first on MedicalResearch.com.
... Read more »

Urszula T. Iwaniec, Ph.D. (2015) Gene Therapy with Leptin Induces Weight Loss. MedicalResearch.com. info:/

  • October 14, 2015
  • 10:53 AM
  • 1,780 views

Feel Our Pain: Empathy and Moral Behavior

by Jalees Rehman in The Next Regeneration

"It's empathy that makes us help other people. It's empathy that makes us moral." The economist Paul Zak casually makes this comment in his widely watched TED talk about the hormone oxytocin, which he dubs the "moral molecule". Zak quotes a number of behavioral studies to support his claim that oxytocin increases empathy and trust, which in turn increases moral behavior. If all humans regularly inhaled a few puffs of oxytocin through a nasal spray, we could become m........ Read more »

De Dreu, C., Greer, L., Van Kleef, G., Shalvi, S., & Handgraaf, M. (2011) Oxytocin promotes human ethnocentrism. Proceedings of the National Academy of Sciences, 108(4), 1262-1266. DOI: 10.1073/pnas.1015316108  

Shalvi S, & De Dreu CK. (2014) Oxytocin promotes group-serving dishonesty. Proceedings of the National Academy of Sciences of the United States of America, 111(15), 5503-7. PMID: 24706799  

Xu X, Zuo X, Wang X, & Han S. (2009) Do you feel my pain? Racial group membership modulates empathic neural responses. The Journal of neuroscience : the official journal of the Society for Neuroscience, 29(26), 8525-9. PMID: 19571143  

  • October 7, 2015
  • 09:00 AM
  • 1,364 views

Twin Sons Of Different Mothers…… Or Fathers

by Mark Lasbury in As Many Exceptions As Rules

Can a pregnant woman get pregnant? Sounds like a riddle, but really it is superfetation. Getting pregnant in two successive cycles and having twins with different fathers really creates a problem in defining what twins actually are. Twins don’t have to be conceived at the same time, born at the same time, have the same father, or even be of the same “race.”... Read more »

Claas, M., Timmermans, A., & Bruinse, H. (2010) Case report: a black and white twin. Journal of Perinatology, 30(6), 434-436. DOI: 10.1038/jp.2009.156  

  • September 30, 2015
  • 08:55 AM
  • 1,135 views

Twins of Different Seasons

by Mark Lasbury in As Many Exceptions As Rules

Twins are born near the same time, that’s one of the things that makes them twins. But do they have to be born close to one another? The record is twins born 104 days apart. The key is to get the twins past 25 weeks so the lungs will be mature enough, but if one twin is delivered, the second might be subjected to delayed interval delivery to give the lungs longer to grow.... Read more »

Reinhard, J., Reichenbach, L., Ernst, T., Reitter, A., Antwerpen, I., Herrmann, E., Schlösser, R., & Louwen, F. (2012) Delayed interval delivery in twin and triplet pregnancies: 6 years of experience in one perinatal center. Journal of Perinatal Medicine, 40(5). DOI: 10.1515/jpm-2011-0267  

Padilla-Iserte, P., Vila-Vives, J., Ferri, B., Gómez-Portero, R., Diago, V., & Perales-Marín, A. (2014) Delayed Interval Delivery of the Second Twin: Obstetric Management, Neonatal Outcomes, and 2-Year Follow-Up. The Journal of Obstetrics and Gynecology of India, 64(5), 344-348. DOI: 10.1007/s13224-014-0544-1  

Lewi, L., Devlieger, R., De Catte, L., & Deprest, J. (2014) Growth discordance. Best Practice , 28(2), 295-303. DOI: 10.1016/j.bpobgyn.2013.12.003  

  • September 16, 2015
  • 09:00 AM
  • 1,185 views

You And Mom Are Never Apart

by Mark Lasbury in As Many Exceptions As Rules

You have more in common with your mom than you might think. Microchimerism means that an individual has cells with two different genetic profiles; some are yours and some are your mom’s. They live in your body for more than 40 years and can affect your health. Some of your cells moved into mom too – and they may help her live longer and avoid breast cancer.... Read more »

Cirello V, Rizzo R, Crippa M, Campi I, Bortolotti D, Bolzani S, Colombo C, Vannucchi G, Maffini MA, de Liso F.... (2015) Fetal cell microchimerism: a protective role in autoimmune thyroid diseases. European journal of endocrinology / European Federation of Endocrine Societies, 173(1), 111-8. PMID: 25916393  

Kamper-Jorgensen, M., Hjalgrim, H., Andersen, A., Gadi, V., & Tjonneland, A. (2013) Male microchimerism and survival among women. International Journal of Epidemiology, 43(1), 168-173. DOI: 10.1093/ije/dyt230  

Eun, J., Guthrie, K., Zirpoli, G., & Gadi, V. (2013) In Situ Breast Cancer and Microchimerism. Scientific Reports. DOI: 10.1038/srep02192  

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