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  • May 21, 2017
  • 11:50 AM
  • 340 views

Predictive Processing: the role of confidence and precision

by Sergio Graziosi in Writing my own user manual - Sergio Graziosi's Blog

This is the second post in a series inspired by Andy Clark’s book “Surfing Uncertainty“. In the previous post I’ve mentioned that an important concept in the Predictive Processing (PP) framework is the role of confidence. Confidence (in a prediction)…Read more ›... Read more »

Kanai R, Komura Y, Shipp S, & Friston K. (2015) Cerebral hierarchies: predictive processing, precision and the pulvinar. Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 370(1668). PMID: 25823866  

  • August 18, 2016
  • 09:54 AM
  • 947 views

Wait, let me google it. On the fall (and rise?) of human memory.

by gdw in FictionalFieldwork

Ruins of a memory palace Once upon a time, there were no computers. And yet, even in the ancient days when writing was not widespread, people told gigantic tales or recited poems of epic proportions. Often more than once. Admittedly, they probably changed a bit along the way, but still the plot remained intact. How […]... Read more »

  • June 1, 2016
  • 12:30 AM
  • 934 views

42: the answer to life, the universe and everything (i.e., consciousness)

by Piter Boll in Earthling Nature

by Piter Kehoma Boll In his work  “The Hitchhiker’s Guide to the Galaxy”, Douglas Adams defined that the answer to life, the universe and everything is 42. Now a group of scientists measured glucose metabolism in brains in a resting … Continue reading →... Read more »

Stender, J., Mortensen, K., Thibaut, A., Darkner, S., Laureys, S., Gjedde, A., & Kupers, R. (2016) The Minimal Energetic Requirement of Sustained Awareness after Brain Injury. Current Biology. DOI: 10.1016/j.cub.2016.04.024  

  • January 13, 2016
  • 10:05 AM
  • 1,250 views

Exercise Puts Me To Sleep – You Too

by Mark Lasbury in As Many Exceptions As Rules

A New Year’s resolution to exercise could also help you sleep. But how? It wears you out and reduces stress, but there is much more. Exercise manipulates the temperature of the body by messing with your brain and modulates immune cytokine levels. It’s true… your immune system controls sleep cycles!... Read more »

  • January 3, 2016
  • 03:55 PM
  • 849 views

Exercise, be smarter, save time

by Patrick Mineault in xcorr

The majority of mortals complain bitterly of the spitefulness of Nature, because we are born for a brief span of life […]. It is not that we have a short space of time, but that we waste much of it. Life is long enough, and it has been given in sufficiently generous measure to allow the […]... Read more »

Spalding KL, Bergmann O, Alkass K, Bernard S, Salehpour M, Huttner HB, Boström E, Westerlund I, Vial C, Buchholz BA.... (2013) Dynamics of hippocampal neurogenesis in adult humans. Cell, 153(6), 1219-27. PMID: 23746839  

Shors TJ, Miesegaes G, Beylin A, Zhao M, Rydel T, & Gould E. (2001) Neurogenesis in the adult is involved in the formation of trace memories. Nature, 410(6826), 372-6. PMID: 11268214  

van Praag H, Christie BR, Sejnowski TJ, & Gage FH. (1999) Running enhances neurogenesis, learning, and long-term potentiation in mice. Proceedings of the National Academy of Sciences of the United States of America, 96(23), 13427-31. PMID: 10557337  

Erickson KI, Voss MW, Prakash RS, Basak C, Szabo A, Chaddock L, Kim JS, Heo S, Alves H, White SM.... (2011) Exercise training increases size of hippocampus and improves memory. Proceedings of the National Academy of Sciences of the United States of America, 108(7), 3017-22. PMID: 21282661  

Hillman CH, Erickson KI, & Kramer AF. (2008) Be smart, exercise your heart: exercise effects on brain and cognition. Nature reviews. Neuroscience, 9(1), 58-65. PMID: 18094706  

Arem H, Moore SC, Patel A, Hartge P, Berrington de Gonzalez A, Visvanathan K, Campbell PT, Freedman M, Weiderpass E, Adami HO.... (2015) Leisure time physical activity and mortality: a detailed pooled analysis of the dose-response relationship. JAMA internal medicine, 175(6), 959-67. PMID: 25844730  

  • October 21, 2015
  • 07:05 PM
  • 245 views

The ‘Glass Brain’ shows neuronal firing in real-time!

by Vaibhav Jain in NEUROFANATIC

Stunning 3D ‘glass brain’ shows neurons firing off in real-time. The structure of the brain is mapped using magnetic resonance imaging (MRI). The user then wears cap covered with electrodes that measure differences in electric potential to record brain activity. This activity is revealed on-screen. The different colors represent the different frequencies of electrical energy in the brain, as […]... Read more »

Mullen T, Kothe C, Chi YM, Ojeda A, Kerth T, Makeig S, Cauwenberghs G, & Jung TP. (2013) Real-time modeling and 3D visualization of source dynamics and connectivity using wearable EEG. 35th Annual International Conference of the IEEE Engineering in Biology and Medicine Society., 2184-7. PMID: 24110155  

  • August 3, 2015
  • 12:00 PM
  • 867 views

Nature Neuroscience paper: “Oscillatory dynamics coordinating human frontal networks in support of goal maintenance”

by Bradley Voytek in Oscillatory Thoughts 2.0

Phew! One of my post-doc papers is finally out in Nature Neuroscience, “Oscillatory dynamics coordinating human frontal networks in support of goal maintenance” (link). (Parenthetical: if this kind of thing interests you, feel free to drop me an email and/or drop by my lab’s posters at SfN (PDF)!) I can’t begin to express, within the constraints of my literary ability, […]... Read more »

Voytek B, Kayser AS, Badre D, Fegen D, Chang EF, Crone NE, Parvizi J, Knight RT, & D'Esposito M. (2015) Oscillatory dynamics coordinating human frontal networks in support of goal maintenance. Nature neuroscience. PMID: 26214371  

  • August 1, 2015
  • 09:42 PM
  • 955 views

The Idiosyncratic Side of Diagnosis by Brain Scan and Machine Learning

by The Neurocritic in The Neurocritic

R2D3R2D3 recently had a fantastic Visual Introduction to Machine Learning, using the classification of homes in San Francisco vs. New York as their example. As they explain quite simply: In machine learning, computers apply statistical learning techniques to automatically identify patterns in data. These techniques can be used to make highly accurate predictions. You should really head over there right now to view it, because it's very impressive.Computational neuroscience types are using machin........ Read more »

  • June 3, 2015
  • 09:15 AM
  • 1,137 views

Left-Handers Have Prettier Brains

by Mark Lasbury in As Many Exceptions As Rules

Take a quick look at the human brain and it seems very symmetrical. Well, it’s not. Which hand you use can help determine just how symmetrical your brain actually is, and for some people that’s really important – they were born with only half a brain!... Read more »

Rogers, L., Zucca, P., & Vallortigara, G. (2004) Advantages of having a lateralized brain. Proceedings of the Royal Society B: Biological Sciences, 271(Suppl_6). DOI: 10.1098/rsbl.2004.0200  

Muckli, L., Naumer, M., & Singer, W. (2009) Bilateral visual field maps in a patient with only one hemisphere. Proceedings of the National Academy of Sciences, 106(31), 13034-13039. DOI: 10.1073/pnas.0809688106  

  • May 28, 2015
  • 12:47 PM
  • 571 views

Neural Communication: Jazz, Not Symphony

by Bradley Voytek in Oscillatory Thoughts 2.0

(This is about my latest paper, “Dynamic Network Communication as a Unifying Neural Basis for Cognition, Development, Aging, and Disease.” This paper was invited as part of a special issue for Biological Psychiatry titled “Cortical Oscillations for Cognitive/Circuit Dysfunction in Psychiatric Disorders,” by the organizing editor, György Buzsáki. Although it was invited, it was still peer-reviewed as normal. This post originally appeared […]... Read more »

  • March 15, 2015
  • 12:54 AM
  • 1,438 views

New approaches to epilepsy treatment: optogenetics and DREADDs

by neurosci in Neuroscientifically Challenged

Epilepsy refers to a group of disorders that are characterized by recurrent seizures. It is a relatively common neurological condition, and is considered the most common serious (implying that there is a risk of mortality) brain disorder, affecting around 2.2 million Americans.The seizures associated with epilepsy are not homogenous; they can have a drastically different presentation depending on the patient, the part of the brain the seizure originates in, and how much of the brain the seizure ........ Read more »

  • February 9, 2015
  • 02:30 PM
  • 1,346 views

Slime mould and researcher set to play piano duet

by GrrlScientist in Maniraptora

SUMMARY: A single-celled organism will perform a piano duet with a computer musician at Plymouth University on 1 March 2015. The public is invited. ... Read more »

Nakagaki Toshiyuki, Yamada Hiroyasu, & Tóth Ágota. (2000) Intelligence: Maze-solving by an amoeboid organism. Nature, 407(470). DOI: 10.1038/35035159  

Saigusa Tetsu, Toshiyuki Nakagaki, & Yoshiki Kuramoto. (2008) Amoebae Anticipate Periodic Events. Physical Review Letters, 100(1). DOI: http://dx.doi.org/10.1103/physrevlett.100.018101  

Miranda Eduardo R. , Adamatzky Andrew, & Jones Jeff . (2011) Sounds Synthesis with Slime Mould of Physarum polycephalum. Journal of Bionic Engineering, 107-113. arXiv: 1212.1203

  • September 14, 2014
  • 02:00 AM
  • 1,299 views

Telepathy is Almost Here

by Viputheshwar Sitaraman in Draw Science

Telepathy is under works; it's just super clunky right now. Non-invasive technology enables brain-to-brain communication by converting words into binary and from binary into pulses of light and back. [Infographic]... Read more »

Grau C, Ginhoux R, Riera A, Nguyen TL, Chauvat H, Berg M, Amengual JL, Pascual-Leone A, & Ruffini G. (2014) Conscious Brain-to-Brain Communication in Humans Using Non-Invasive Technologies. PloS one, 9(8). PMID: 25137064  

  • June 25, 2014
  • 08:58 PM
  • 910 views

Time weaves memories into patterns

by Shelly Fan in Neurorexia

When I get a craving for Cote d’Or chocolate, I always hit up London Drugs. It’s not the only grocer around that carries the brand,...... Read more »

Richards BA, Xia F, Santoro A, Husse J, Woodin MA, Josselyn SA, & Frankland PW. (2014) Patterns across multiple memories are identified over time. Nature neuroscience. PMID: 24880213  

  • January 13, 2014
  • 09:49 PM
  • 1,216 views

Using Ultrasound to Boost Brain Performance

by Jason Carr in Wired Cosmos

Virginia Tech Carilion Research Institute scientists have demonstrated that ultrasound directed to a specific region of the brain can boost performance in sensory discrimination. Whales, bats, and even praying mantises use ultrasound as a sensory guidance system — and now a new study has found that ultrasound can modulate brain activity to heighten sensory perception … Read More →... Read more »

Wynn Legon, Tomokazu F Sato, Alexander Opitz, Jerel Mueller, Aaron Barbour, Amanda Williams, & William J Tyler. (2014) Transcranial focused ultrasound modulates the activity of primary somatosensory cortex in humans. Nature Neuroscience. info:/10.1038/nn.3620

  • January 8, 2014
  • 09:15 AM
  • 1,082 views

Exercise Puts Me To Sleep – You Too

by Mark Lasbury in As Many Exceptions As Rules

A New Year’s resolution to exercise could also help you sleep. But how? Sheer exhaustion is one way and reducing stress is another, but there is much more. Research is showing that exercise can induce sleep in the anterior hypothalamus and preoptic nucleus by either manipulation the temperature of the body or by modulating cytokine levels. Studies indicate that decreased temperature after exercise stimulate the brain to inhibit wakefulness signals modulated by orexin/hypocretin. Additional........ Read more »

  • October 11, 2013
  • 01:19 PM
  • 996 views

A new quantitative measure of consciousness: measuring the complexity of neural ripples

by Robert Seymour in NeuroFractal

It has been suggested that behavioural measures of consciousness result in an alarmingly high 43% misdiagnosis rate for Vegetative State (VS) patients – a state in which people completely lack cognitive function but still show sleep-wake cycles and often open their eyes. Could there be a more reliable neural marker? In a recent paper Casali et al., (2013) suggests that there might be. ... Read more »

Casali AG, Gosseries O, Rosanova M, Boly M, Sarasso S, Casali KR, Casarotto S, Bruno MA, Laureys S, Tononi G.... (2013) A theoretically based index of consciousness independent of sensory processing and behavior. Science translational medicine, 5(198). PMID: 23946194  

  • October 4, 2013
  • 09:13 AM
  • 1,916 views

Why PLOS ONE is no longer my default journal

by Juan Nunez-Iglesias in I Love Symposia!

Time-to-publication at the world’s biggest scientific journal has grown dramatically, but the nail in the coffin was its poor production policies. When PLOS ONE was announced in 2006, its charter immediately resonated with me. This would be the first journal where only scientific accuracy mattered. Judgments of “impact” and “interest” would be left to posterity, […]... Read more »

  • October 2, 2013
  • 11:21 AM
  • 1,255 views

We Have the Technology…

by Roli Roberts in PLOS Biologue

“Gentlemen, we can rebuild him. We have the technology. We have the capability to make the world’s first bionic man. Steve Austin will be that man. Better than he was before. Better…stronger…faster.”

Readers of a certain age will tingle with recognition at those words, intoned over the intro to ’70s TV series “The Six Million Dollar Man“, promising the bodily reconstruction of a seriously injured astronaut. Back then it was distant science fiction, but fast-forward 30 years to........ Read more »

Carmena JM, Lebedev MA, Crist RE, O'Doherty JE, Santucci DM, Dimitrov DF, Patil PG, Henriquez CS, & Nicolelis MA. (2003) Learning to control a brain-machine interface for reaching and grasping by primates. PLoS biology, 1(2). PMID: 14624244  

  • September 11, 2013
  • 12:56 PM
  • 1,198 views

How Schizophrenia Affects the Brain

by Jason Carr in Wired Cosmos

It’s hard to fully understand a mental disease like schizophrenia without peering into the human brain. Now, a study by University of Iowa psychiatry professor Nancy Andreasen uses brain scans to document how schizophrenia impacts brain tissue as well as the effects of anti-psychotic drugs on those who have relapses. Andreasen’s study (cited below), published … Read More →... Read more »

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