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  • December 17, 2016
  • 05:51 AM
  • 347 views

Pregnancy influenza infection not linked to offspring autism

by Paul Whiteley in Questioning Answers

"There was no association between maternal influenza [flu] infection anytime during pregnancy and increased ASD [autism spectrum disorder] risk."So said the findings reported by Ousseny Zerbo and colleagues [1] continuing a research theme from this author (see here for example) looking at how various infections 'encountered' during critical periods of pregnancy may / may not impact on offspring autism risk. This time around the focus was on viral infections and in partic........ Read more »

  • December 16, 2016
  • 05:25 AM
  • 328 views

Patient participation in clinical trials

by Joana Guedes in BHD Research Blog

Clinical trials are crucial to help doctors and scientists understand how to safely treat a particular condition, to evaluate new treatments and to test drug safety and efficacy. They have an important role in every step of managing a condition with different clinical trials helping with prevention, diagnosis, treatments and follow-up support.... Read more »

  • December 16, 2016
  • 04:30 AM
  • 293 views

Frequency and Location of Head Impacts in Division 1 Men’s Lacrosse Players

by Patricia Kelshaw, MS, LAT, ATC in Sports Medicine Research (SMR): In the Lab & In the Field

Player position and session type such as practice or game are the main factors that influence head impact frequencies and magnitudes for lacrosse athletes.... Read more »

  • December 16, 2016
  • 03:16 AM
  • 341 views

Non-febrile seizures in children with autism vs unaffected siblings

by Paul Whiteley in Questioning Answers

"Children with idiopathic ASD [autism spectrum disorder] are significantly more likely to have non-febrile seizures than their unaffected siblings, suggesting that non-febrile seizures may be ASD-specific."So said the findings from Lena McCue and colleagues [1] (open-access) continuing a research theme looking at one of the important 'comorbidities' that seems to be over-represented when it comes to a diagnosis of autism (see here). Idiopathic autism or ASD refers to autism as the........ Read more »

  • December 15, 2016
  • 04:30 AM
  • 317 views

Cortisol and Testosterone Levels Following Exhaustive Endurance Exercise: How Much Recovery Do Athletes Really Need?

by Jennifer Fields in Sports Medicine Research (SMR): In the Lab & In the Field

Following high-intensity endurance exercise, recovery may require 48-72 hours for cortisol and testosterone to return back to resting levels. ... Read more »

Anderson, T., Lane, A., & Hackney, A. (2016) Cortisol and testosterone dynamics following exhaustive endurance exercise. European Journal of Applied Physiology, 116(8), 1503-1509. DOI: 10.1007/s00421-016-3406-y  

  • December 15, 2016
  • 02:59 AM
  • 402 views

ADHD, not autism, might count when it comes to 'comorbid psychiatric symptomatology'

by Paul Whiteley in Questioning Answers

A quote to begin this fairly brief post: "Our study concluded that higher levels of ADHD [attention-deficit hyperactivity disorder] severity-not ASD [autism spectrum disorder] severity-were associated with a higher prevalence of comorbid psychiatric symptomatology in school-age children with ASD. These findings may encourage clinicians to thoroughly assess ADHD symptomatology in ASD children to better inform treatment planning."That was the research bottom line reported by Ro........ Read more »

  • December 14, 2016
  • 04:30 AM
  • 308 views

Identifying Athletes at Risk for Chronic Ankle Instability

by Matt Prebble in Sports Medicine Research (SMR): In the Lab & In the Field

The jump-landing protocol was able to distinguish between healthy, ‘coper’, and unstable ankles. This protocol may be useful for identifying athletes at increased risk for injury, and as a return to play indicator following rehabilitation.... Read more »

  • December 14, 2016
  • 03:07 AM
  • 368 views

Urinary metabolomics in autism turns up tryptophan (again)

by Paul Whiteley in Questioning Answers

"The tryptophan metabolic pathway collectively displays the largest perturbations in ASD [autism spectrum disorder]."So said the findings reported by Federica Gevi and colleagues [1] (open-access) who provide yet more 'metabolomic' data when it comes to autism to add to the already quite voluminous peer-reviewed matter on this topic (see here for example).Just in case you aren't analytical chemistry-saavy, metabolomics is basically the study of the various chemical fingerprints that th........ Read more »

  • December 13, 2016
  • 04:30 AM
  • 316 views

Can Using a Whole Body Vibration Warm-up Give Athletes Quicker Feet?

by Stuart McCrory in Sports Medicine Research (SMR): In the Lab & In the Field

Whole-body vibration improves performance on quick feet test when compared to a traditional warm-up.... Read more »

Donahue RB, Vingren JL, Duplanty AA, Levitt DE, Luk HY, & Kraemer WJ. (2016) Acute Effect of Whole-Body Vibration Warm-up on Footspeed Quickness. Journal of strength and conditioning research, 30(8), 2286-91. PMID: 27328378  

  • December 13, 2016
  • 04:25 AM
  • 367 views

'My child is not talking'. Online concerns and internet-based screening for autism?

by Paul Whiteley in Questioning Answers

"Online communities are used as platforms by parents to verify developmental and health concerns related to their child."That was the starting point for the study results reported by Ben-Sasson & Yom-Tov [1] (open-access available here) who approached an increasingly important issue related to how the Internet and social media in particular, is fast becoming one of the 'go-to' options when it comes to parental concerns about their child's development and the question: could it be autism........ Read more »

  • December 12, 2016
  • 04:37 AM
  • 348 views

Maternal immune activation (MIA) and Old World monkeys

by Paul Whiteley in Questioning Answers

Old World monkeys detailed in the title of this post, specifically refers to a type of animal called a rhesus macaque who were the 'participants' of choice as detailed in a recent study by Destanie Rose and colleagues [1] looking at a concept called maternal immune activation (MIA).Those who followed this blog down the years will no doubt have seen me discuss MIA before in the context of autism and/or schizophrenia (see here for example). The basic theory is that whilst in-utero a........ Read more »

  • December 12, 2016
  • 04:30 AM
  • 317 views

Substance Use by Gender and Race Among Teenage Athletes

by Jessica Pope in Sports Medicine Research (SMR): In the Lab & In the Field

While general substance use patterns are seen in adolescent athletes, some gender and racial/ethnic groups are at more risk than others. Prevention and educational programs should be designed with this in mind.... Read more »

Parent, M., Bradstreet, T., Piper, M., Brace, T., & Parkman, T. (2016) Racial Disparities in Substance Use by Sport Participation Among High School Students. Journal of Studies on Alcohol and Drugs, 77(6), 980-985. DOI: 10.15288/jsad.2016.77.980  

  • December 10, 2016
  • 04:48 PM
  • 317 views

Yet again, more of the same …

by Craig Payne in Running Research Junkie

Yet again, more of the same …... Read more »

  • December 10, 2016
  • 04:28 AM
  • 416 views

"Are we expecting too much from the extreme male brain theory of autism?"

by Paul Whiteley in Questioning Answers

The title of this post reflects the commentary published by Andrew Whitehouse [1] (open-access) discussing the meaning of the findings reported by Kung and colleagues [2] who quite categorically stated that there was: "No relationship between prenatal androgen exposure and autistic traits" in their study.OK, androgen exposure and psychology basically refers to the extreme male brain theory and autism which suggests that the so-called over-representation of autism in males is potentiall........ Read more »

  • December 9, 2016
  • 04:53 AM
  • 381 views

'Big data' Taiwan and schizophrenia risk

by Paul Whiteley in Questioning Answers

Today I bring the findings reported by Chou and colleagues [1] (open-access available here) to the blogging table and how the research might of the Taiwan National Health Insurance Database (NHIRD) brought it's 'big data' ("n = 23 422 955") to bear on the question: what is the risk of developing schizophrenia where one or more first-degree or other relatives are affected?The answer: "Having an affected co-twin, first-degree relative, second-degree relative, or spouse was associate........ Read more »

  • December 9, 2016
  • 04:30 AM
  • 333 views

Balancing on the BACK

by Abbis Haider Jaffri in Sports Medicine Research (SMR): In the Lab & In the Field

Patients who suffer from current or previous symptoms of lower back pain demonstrated lower reach distances in the posterior directions of the Y-Balance Test compared to healthy individuals.... Read more »

  • December 8, 2016
  • 03:14 PM
  • 196 views

ExAC presents a catalogue of human protein-coding genetic variation

by Kamil S. Jaron in genome ecology evolution etc

Exploration of variability of human genomes represents a key step in the holy grail of human genetics – to link genotypes with phenotypes, it also provides insights to human evolution and history. For this purpose Exome Aggregation Consortium (ExAC) have … Continue reading →... Read more »

Lek M, Karczewski KJ, Minikel EV, Samocha KE, Banks E, Fennell T, O'Donnell-Luria AH, Ware JS, Hill AJ, Cummings BB.... (2016) Analysis of protein-coding genetic variation in 60,706 humans. Nature, 536(7616), 285-91. PMID: 27535533  

  • December 8, 2016
  • 04:51 AM
  • 367 views

Prescription medication use and autism: good medicines management required

by Paul Whiteley in Questioning Answers

"Prescription drug use and polypharmacy rates among adults with ASD [autism spectrum disorder] are substantially higher than those in an age-, sex-, and race-matched cohort of adults without ASD."That sentence taken from the paper by Rini Vohra and colleagues [1] (open-access available here) is probably not likely to win any 'novel findings of the year' awards given the already quite voluminous data published on the medication use and autism (see here for example). What gives the ........ Read more »

  • December 7, 2016
  • 12:36 PM
  • 358 views

Pregnancy folic acid and offspring autism systematically reviewed

by Paul Whiteley in Questioning Answers

"A total of 22 original papers that examined the association between folic acid supplementation in human pregnancy and neurodevelopment/autism were identified after the screening, with 15 studies showing a beneficial effect of folic acid supplementation on neurodevelopment/autism, 6 studies showed no statistically significant difference, while one study showed a harmful effect in > 5 mg folic acid supplementation/day during pregnancy."That rather long quote taken from the paper published by Y........ Read more »

  • December 7, 2016
  • 04:30 AM
  • 315 views

Thinking about high-dose vitamin D supplements for your athletes? Make sure the dose is right.

by Kyle Harris in Sports Medicine Research (SMR): In the Lab & In the Field

A Blanket high dose vitamin D supplement plan results in elevated levels of vitamin D metabolites after the supplementation is completed. This could result in lower than normal levels of vitamin D, which is the opposite effect of the intended supplementation.... Read more »

Owens DJ, Tang JC, Bradley WJ, Sparks SA, Fraser WD, Morton JP, & Close GL. (2016) Efficacy of High Dose Vitamin D Supplements for Elite Athletes. Medicine and science in sports and exercise. PMID: 27741217  

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