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  • May 30, 2015
  • 03:07 AM
  • 18 views

Autism and altered levels of essential fatty acids

by Paul Whiteley in Questioning Answers

Brigandi et al. 2015. Int. J. Mol. Sci. 16: 10061-10076.A quote to begin this post is taken from the paper by Sarah Brigandi and colleagues [1] (open-access available here): "Our study demonstrates an alteration in the PUFA [polyunsaturated fatty acids] profile and increased production of a PUFA-derived metabolite in autistic patients, supporting the hypothesis that abnormal lipid metabolism is implicated in autism."The Brigandi results were based on the analysis of blood samples for fatty ........ Read more »

Brigandi SA, Shao H, Qian SY, Shen Y, Wu BL, & Kang JX. (2015) Autistic Children Exhibit Decreased Levels of Essential Fatty Acids in Red Blood Cells. International journal of molecular sciences, 16(5), 10061-10076. PMID: 25946342  

  • May 29, 2015
  • 03:45 AM
  • 48 views

Reduced rumination and aggressive thoughts from a probiotic?

by Paul Whiteley in Questioning Answers

I've taken my time to come to discussing the findings from Laura Steenbergen and colleagues [1] (open-access) providing "the first evidence that the intake of probiotics may help reduce negative thoughts associated with sad mood." It's not that I didn't find such results to be really interesting and having potential for quite a few different areas of psychiatry, but rather that other blogging topics have popped up in the meantime. No mind, we're here now.Based on a growing evidence base sug........ Read more »

  • May 29, 2015
  • 12:05 AM
  • 33 views

Non-Thermal Ultrasound Could Help Keep Your Reflexes from Inhibiting Your Rehab

by Jane McDevitt in Sports Medicine Research (SMR): In the Lab & In the Field

Quadriceps spinal-reflexive excitability was greater 20 minutes following non-thermal therapeutic ultrasound compared with a sham treatment among individuals with a history of knee injury and quadriceps dysfunction.... Read more »

  • May 28, 2015
  • 08:47 AM
  • 47 views

From Herb Garden To Medicine Cabinet: Developing A New Drug for Malaria

by Bill Sullivan in The 'Scope

A new study has identified how the herb Dichroa febrifuga treats malaria, which is helping in the design of better therapies.... Read more »

Herman JD, Pepper LR, Cortese JF, Estiu G, Galinsky K, Zuzarte-Luis V, Derbyshire ER, Ribacke U, Lukens AK, Santos SA.... (2015) The cytoplasmic prolyl-tRNA synthetase of the malaria parasite is a dual-stage target of febrifugine and its analogs. Science translational medicine, 7(288). PMID: 25995223  

  • May 28, 2015
  • 03:28 AM
  • 64 views

The autisms, case reports and two 'intervention' options

by Paul Whiteley in Questioning Answers

I'm looking at two papers today which I'd like to think cover the title of this post pretty well dealing with the plurality of autism - the autisms - and the idea that intervention or management-wise, there is no 'one size fits all' when it comes to the autisms.First up are the findings reported by Ziats and colleagues [1] who presented results for a child - "A 4-year-old male with autism and two episodes of neurodevelopmental regression" - who was also found to have a "mutation in the TMLHE gen........ Read more »

  • May 27, 2015
  • 03:52 PM
  • 66 views

Expanding the code of life with new ‘letters’

by Dr. Jekyll in Lunatic Laboratories

The DNA encoding all life on Earth is made of four building blocks called nucleotides, commonly known as “letters,” that line up in pairs and twist into a double helix. Now, two groups of scientists are reporting for the first time that two new nucleotides can do the same thing — raising the possibility that entirely new proteins could be created for medical uses.... Read more »

Georgiadis, M., Singh, I., Kellett, W., Hoshika, S., Benner, S., & Richards, N. (2015) Structural Basis for a Six Nucleotide Genetic Alphabet. Journal of the American Chemical Society, 2147483647. DOI: 10.1021/jacs.5b03482  

Zhang, L., Yang, Z., Sefah, K., Bradley, K., Hoshika, S., Kim, M., Kim, H., Zhu, G., Jiménez, E., Cansiz, S.... (2015) Evolution of Functional Six-Nucleotide DNA. Journal of the American Chemical Society. DOI: 10.1021/jacs.5b02251  

  • May 27, 2015
  • 09:40 AM
  • 55 views

Video Tip of the Week: PANDA (Pathway AND Annotation) Explorer for lists of genes

by Mary in OpenHelix

This week’s Video Tip of the Week demonstrates PANDA, a tool for generating and examining annotations that are available for a list of genes, and evaluating them in the context of pathways. Two great tastes that taste great together, you know? So have a look at how PANDA can help you and your team to […]... Read more »

  • May 27, 2015
  • 06:40 AM
  • 44 views

Some Birth Control Pills Have Slightly Higher Risk Of Venous Thromboembolism

by Marie Benz in MedicalResearch.com

MedicalResearch.com Medical Research Interviews and News
MedicalResearch.com Interview with: Yana Vinogradova, Research Fellow Division of Primary Care School of Medicine University of Nottingham Medical Research: What is the background for this study? What are the main findings? Response: Combined oral contraceptives are an effective method of … Continue reading →
The post Some Birth Control Pills Have Slightly Higher Risk Of Venous Thromboembolism appeared first on MedicalResearch......... Read more »

MedicalResearch.com Interview with:, & Yana Vinogradova, Research Fellow. (2015) Some Birth Control Pills Have Slightly Higher Risk Of Venous Thromboembolism. MedicalResearch.com. info:/

  • May 27, 2015
  • 06:32 AM
  • 42 views

Soy Supplement Did Not Improve Asthma Symptoms

by Marie Benz in MedicalResearch.com

MedicalResearch.com Medical Research Interviews and News
MedicalResearch.com Interview with: Lewis J. Smith, MD Professor of Medicine and Associate Vice President for Research Northwestern University and the Feinberg School of Medicine Chicago, IL 60611 Medical Research: What is the background for this study? What are the main … Continue reading →
The post Soy Supplement Did Not Improve Asthma Symptoms appeared first on MedicalResearch.com Medical Research Interviews and News.
... Read more »

MedicalResearch.com Interview with: Lewis J. Smith, MD. (2015) Soy Supplement Did Not Improve Asthma Symptoms. MedicalResearch.com. info:/

  • May 27, 2015
  • 06:18 AM
  • 34 views

New Optical Tool May Identify Patients At High Risk Of Recurrent Prostate Cancer

by Marie Benz in MedicalResearch.com

MedicalResearch.com Medical Research Interviews and News
MedicalResearch.com Interview with: Gabriel Popescu PhD Associate Professor, Department of Electrical and Computer Engineering & Bioengineering University of Illinois at Urbana-Champaign Beckman Institute for Advanced Science and Technology Urbana, IL 61801 Medical Research: What is the background for this study? … Continue reading →
The post New Optical Tool May Identify Patients At High Risk Of Recurrent Prostate Cancer a........ Read more »

MedicalResearch.com Interview with: Gabriel Popescu PhD. (2015) New Optical Tool May Identify Patients At High Risk Of Recurrent Prostate Cancer. MedicalResearch.com. info:/

  • May 27, 2015
  • 03:08 AM
  • 43 views

Predicting the onset of schizophrenia?

by Paul Whiteley in Questioning Answers

"A lower level of inflammatory response indicated by PTX3 [pentraxin-3] might be implicated in developing schizophrenia."That was the primary conclusion reported by Natalya Weber and colleagues [1] (open-access here) who "tested preonset serum specimens from 160 US military service members who were later diagnosed with schizophrenia or bipolar disorder and 160 matched controls without psychiatric disorders."PTX-3 by the way, is a compound of some note when it comes to the concept of in........ Read more »

Weber NS, Larsen RA, Yolken RH, Cowan DN, Boivin MR, & Niebuhr DW. (2015) Predictors of the Onset of Schizophrenia in US Military Personnel. The Journal of nervous and mental disease, 203(5), 319-24. PMID: 25919381  

  • May 27, 2015
  • 12:05 AM
  • 35 views

2 Out of 3 Is Bad: Starter, Disability, and Poor Core Endurance

by Nicole Cattano in Sports Medicine Research (SMR): In the Lab & In the Field

A college football player was 5.3 times more likely to have an injury during a season if he was a starter, had poor core endurance, and reported more low back disability. Assessing for these things during your preseason screening can help identify at-risk individuals who may benefit from injury prevention programs.... Read more »

  • May 26, 2015
  • 08:07 PM
  • 25 views

Ultrasound Able To Reposition and Facilitate Passage Of Kidney Stones

by Marie Benz in MedicalResearch.com

MedicalResearch.com Medical Research Interviews and News
MedicalResearch.com Interview with: Dr. Michael Bailey, Ph.D. Senior Principal Engineer Assistant Professor, Mechanical Engineering and Adjunct Assistant Professor, Urology University of Washington Medical Research: What is the background for this study? What are the main findings? Dr. Bailey: Ultrasonic propulsion … Continue reading →
The post Ultrasound Able To Reposition and Facilitate Passage Of Kidney Stones appeared first........ Read more »

MedicalResearch.com Interview with: Dr. Michael Bailey, Ph.D., Senior Principal Engineer, Assistant Professor, Mechanical Engineering, and Adjunct Assistant Professor, Urology, & University of Washington. (2015) Ultrasound Able To Reposition and Facilitate Passage Of Kidney Stones. MedicalResearch.com. info:/

  • May 26, 2015
  • 06:42 PM
  • 29 views

More Adults Homebound Than In Nursing Homes

by Marie Benz in MedicalResearch.com

MedicalResearch.com Medical Research Interviews and News
MedicalResearch.co Interview with: Katherine Ornstein, PhD MPH Assistant Professor Brookdale Department of Geriatrics and Palliative Medicine Institute for Translational Epidemiology Icahn School of Medicine at Mount Sinai New York, NY 10029 Medical Research: What is the background for this study? … Continue reading →
The post More Adults Homebound Than In Nursing Homes appeared first on MedicalResearch.com Medical Research Int........ Read more »

MedicalResearch.co Interview with: Katherine Ornstein, PhD MPH, Assistant Professor, & Brookdale Department of Geriatrics and Palliative Medicine. (2015) More Adults Homebound Than In Nursing Homes. MedicalResearch.com. info:/

  • May 26, 2015
  • 05:00 PM
  • 26 views

2-3 Cups of Coffee Daily Linked To Lower Odds Of Erectile Dysfunction

by Marie Benz in MedicalResearch.com

MedicalResearch.com Medical Research Interviews and News
MedicalResearch.com Interview with: David S. Lopez, Dr.P.H., M.P.H. Assistant professor University of Texas Health School of Public Health Medical Research: What is the background for this study? What are the main findings? Dr. Lopez: Coffee, and its most studied component, … Continue reading →
The post 2-3 Cups of Coffee Daily Linked To Lower Odds Of Erectile Dysfunction appeared first on MedicalResearch.com Medical Research I........ Read more »

MedicalResearch.com Interview with: David S. Lopez, Dr.P.H., M.P.H. (2015) 2-3 Cups of Coffee Daily Linked To Lower Odds Of Erectile Dysfunction. MedicalResearch.com. info:/

  • May 26, 2015
  • 04:39 PM
  • 24 views

Not All Biologics For Psoriasis Carry Same Risk Of Serious Infections

by Marie Benz in MedicalResearch.com

MedicalResearch.com Medical Research Interviews and News
MedicalResearch.com Interview with: Robert E Kalb, M.D. Clinical Professor of Dermatology State University of New York at Buffalo School of Medicine and Biomedical Sciences Buffalo Medical Group, P.C. Buffalo, NY 14221 Medical Research: What is the background for this study? … Continue reading →
The post Not All Biologics For Psoriasis Carry Same Risk Of Serious Infections appeared first on MedicalResearch.com Medical Research ........ Read more »

MedicalResearch.com Interview with: Robert E Kalb, M.D., Clinical Professor of Dermatology, & State University of New York at Buffalo School of Medicine and Biomedical Sciences. (2015) Not All Biologics For Psoriasis Carry Same Risk Of Serious Infections. MedicalResearch.com. info:/

  • May 26, 2015
  • 04:14 PM
  • 23 views

Molecule May Help Ovarian Cancer Patients Overcome Chemotherapy Resistance

by Marie Benz in MedicalResearch.com

MedicalResearch.com Medical Research Interviews and News
MedicalResearch.com Interview with: Wei Zhang, Ph.D., Professor Department of Pathology Director, Cancer Genomics Core Lab University of Texas MD Anderson Cancer Center Houston, Texas 77030 Medical Research: What is the background for this study? What are the main findings? Dr. … Continue reading →
The post Molecule May Help Ovarian Cancer Patients Overcome Chemotherapy Resistance appeared first on MedicalResearch.com Medical R........ Read more »

MedicalResearch.com Interview with: Wei Zhang, Ph.D., Professor, Department of Pathology, Director, Cancer Genomics Core Lab, University of Texas MD Anderson Cancer Center, & Houston, Texas 77030. (2015) Molecule May Help Ovarian Cancer Patients Overcome Chemotherapy Resistance. MedicalResearch.com. info:/

  • May 26, 2015
  • 03:43 PM
  • 20 views

Plant-Based Vegan Diet May Improve Diabetic Neuropathy Pain, Lower Body Weight

by Marie Benz in MedicalResearch.com

MedicalResearch.com Medical Research Interviews and News
MedicalResearch.com Interview with: Ulka Agarwal, M.D. California State University, East Bay Student Health and Counseling Services Hayward, CA MedicalResearch: What is the background for this study? What are the main findings? Dr. Agarwal: Diabetic peripheral neuropathy affects 60 percent of … Continue reading →
The post Plant-Based Vegan Diet May Improve Diabetic Neuropathy Pain, Lower Body Weight appeared first on MedicalRes........ Read more »

MedicalResearch.com Interview with: Ulka Agarwal, M.D. California State University, East Bay, Student Health and Counseling Services, & Hayward, CA. (2015) Plant-Based Vegan Diet May Improve Diabetic Neuropathy Pain, Lower Body Weight. MedicalResearch.com. info:/

  • May 26, 2015
  • 02:19 PM
  • 17 views

Aflatoxins From Food May Increase Risk Of Gallbladder Cancer

by Marie Benz in MedicalResearch.com

MedicalResearch.com Medical Research Interviews and News
MedicalResearch.com Interview with: Catterina Ferreccio, MD, MPH School of Medicine Pontificia Universidad Católica de Chile Santiago, Chile Medical Research: What is the background for this study? What are the main findings? Dr. Ferreccio: In Chile, gallbladder cancer (GBC) is the 2nd highest … Continue reading →
The post Aflatoxins From Food May Increase Risk Of Gallbladder Cancer appeared first on MedicalResearch.com Medi........ Read more »

MedicalResearch.com Interview with: Catterina Ferreccio, MD, MPH, School of Medicine, Pontificia Universidad Católica de Chile, & Santiago, Chile. (2015) Aflatoxins From Food May Increase Risk Of Gallbladder Cancer. MedicalResearch.com. info:/

  • May 26, 2015
  • 01:30 PM
  • 37 views

Researchers find essential fats for brain growth

by Dr. Jekyll in Lunatic Laboratories

New research has proved that certain special fats found in blood are essential for human brain growth and function. The two studies showed that mutations in the protein Mfsd2a causes impaired brain development in humans. Mfsd2a is the transporter in the brain for a special type of fat called lysophosphatidylcholines (LPCs) — composed of essential fatty acids like omega-3. These studies show, for the first time, the crucial role of these fats in human brain growth and function.... Read more »

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