We know from the work of Nora Volkow and others that meth abusers have chronically low levels of dopamine D2 receptors in their brains. But what is going on in the rest of the body when methamphetamine addiction is running full force?... Read more »
Sun, L., Li, H., Seufferheld, M., Walters, K., Margam, V., Jannasch, A., Diaz, N., Riley, C., Sun, W., Li, Y.... (2011) Systems-Scale Analysis Reveals Pathways Involved in Cellular Response to Methamphetamine. PLoS ONE, 6(4). DOI: 10.1371/journal.pone.0018215
A Friday Weird Science guest post on Neurotic Physiology takes a humorous look at anogenital distance and its implication for fertility in adult males.... Read more »
Eisenberg, M., Hsieh, M., Walters, R., Krasnow, R., & Lipshultz, L. (2011) The Relationship between Anogenital Distance, Fatherhood, and Fertility in Adult Men. PLoS ONE, 6(5). DOI: 10.1371/journal.pone.0018973
HIV virus rapidly undergoes mutation, which is main hurdle in developing vaccine against HIV.There is a region on HIV virus which shows less variations, called as Cd4 binding site ,therefore a protein which stimulate antibody formation against this region can be developed and used as a vaccine.
Researchers at Vaccine Research Center (VRC) and the National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health have studied genes which code for such proteins which can........ Read more »
B V Waghmare. (2011) HIV vaccine development : Proteins which trains B Cells for production of antibodies which successfully neutralize HIV by binding with it . http://bvwaghmare.blogspot.com. info:/(DOI/arXiv/etc.)
European Monitoring Centre for Drugs and Drug Addiction confirms that prohibition does not appear to effect levels of cannabis use in any way... Read more »
The european monitoring centre for drugs and drug addiction. (2011) The state of the drugs problem in Europe . Annual Report. info:/
A team of researchers from the Harvard School of Public Health in Boston have studied more than 120,000 people over 30 years to find that ‘red meat consumption is associated with an increased risk of total, CVD [Cardiovascular disease], and cancer mortality.’... Read more »
Pan, A., Sun, Q., Bernstein, A., Schulze, M., Manson, J., Stampfer, M., Willett, W., & Hu, F. (2012) Red Meat Consumption and Mortality: Results From 2 Prospective Cohort Studies. Archives of Internal Medicine. DOI: 10.1001/archinternmed.2011.2287
A new study that raised concerns about exercise should instead raise concerns about obesity.... Read more »
Claude Bouchard, Steven Blair, Timothy Church, Conrad Earnest, James Hagberg, Keijo Häkkinen, Nathan Jenkins, Laura Karavirta, William Kraus, Arthur Leon.... (2012) Adverse Metabolic Response to Regular Exercise: Is It a Rare or Common Occurrence?. PLOS One, 7(5). info:/10.1371/journal.pone.0037887
New research published in Pediatrics suggests that children living with a dog are significantly healthier than those living without it. The researchers followed up 397 Finnish children, asking their parents to fill in weekly questionnaires about their health until they were 1 year old. Scientists believe that this is so because dog contact helps the babies build up their immune system.... Read more »
Eija Bergroth, Sami Remes, Juha Pekkanen, Timo Kauppila, Gisela Büchele, & Leea Keski-Nisula. (2012) Respiratory Tract Illnesses During the First Year of Life: Effect of Dog and Cat Contacts. Pediatrics. info:/10.1542/peds.2011-2825
Researchers at the University of Essex, in the UK, have found that babies born to women who kept working during their eighth month of pregnancy tend to weight 230g less than those born to mothers who stopped working. The harm was bigger when the women had lower levels of education, while there was no harm at all when they were younger than 24.... Read more »
Emilia Del Bono, John Ermisch, & Marco Francesconi. (2012) Intrafamily Resource Allocations: A Dynamic Structural Model of Birth Weight. Journal of Labor Economics. DOI: 10.1086/664831
What is harder to resist? Checking your Twitter or Facebook account at work or eating a delicious, but fattening snack when you try to watch your calories? Both are inner conflicts, best described as 'I really want to do this, but I should not'.
This blog post looks at the paper of Wilhelm Hofmann, Kathlees Vohs and Roy Baummeister who recently tried to answer these questions in their Everyday Temptation Study. ... Read more »
Hofmann W, Baumeister RF, Förster G, & Vohs KD. (2012) Everyday temptations: an experience sampling study of desire, conflict, and self-control. Journal of personality and social psychology, 102(6), 1318-35. PMID: 22149456
... Read more »
Hadley J. (2003) Sicker and poorer--the consequences of being uninsured: a review of the research on the relationship between health insurance, medical care use, health, work, and income. Medical care research and review : MCRR, 60(2 Suppl). PMID: 12800687
Tempting snacks placed right near the checkout counter can be hard to resist. Even though you know buying one is not in your best interest, they catch attention. These high-profit 'grap-and-go' snacks are particularly hard to ignore at the end of a shopping trip after making dozens of decisions. This blog post discusses a recent paper in which we studied whether assortment structure and accessibility of healthier snacks influences consumer choices. ... Read more »
van Kleef E, Otten K, & van Trijp HC. (2012) Healthy snacks at the checkout counter: A lab and field study on the impact of shelf arrangement and assortment structure on consumer choices. BMC public health, 12(1), 1072. PMID: 23231863
Response to absurd assertion that alcoholic beverages are simply vices.... Read more »
Frozza, R., Bernardi, A., Hoppe, J., Meneghetti, A., Matté, A., Battastini, A., Pohlmann, A., Guterres, S., & Salbego, C. (2013) Neuroprotective Effects of Resveratrol Against Aβ Administration in Rats are Improved by Lipid-Core Nanocapsules. Molecular Neurobiology. DOI: 10.1007/s12035-013-8401-2
Summary of common myths and why they are wrong.... Read more »
De Wals P, Deceuninck G, Toth E, Boulianne N, Brunet D, Boucher RM, Landry M, & De Serres G. (2012) Risk of Guillain-Barré syndrome following H1N1 influenza vaccination in Quebec. JAMA : the Journal of the American Medical Association, 308(2), 175-81. PMID: 22782419
I am going to discuss the failings of the PREDIMED study, real and imagined. I will do this in a Question & Answer style. Several questions are inspired by theheart.org and NEJM comments and even statements by the low fat "gurus", Essselstyn, Ornish, McDougall or Pritikin. It is no surprise they are up in arms after the study has been published. It threatens their livelihood.... Read more »
Estruch, R., Ros, E., Salas-Salvadó, J., Covas, M., Corella, D., Arós, F., Gómez-Gracia, E., Ruiz-Gutiérrez, V., Fiol, M., Lapetra, J.... (2013) Primary Prevention of Cardiovascular Disease with a Mediterranean Diet. New England Journal of Medicine, 368(14), 1279-1290. DOI: 10.1056/NEJMoa1200303
Feeling tired? I know I am. But what is it that makes us feel like we need to sleep? And what keeps us awake?
Within our bodies, a lot of systems work antagonistically to maintain homeostasis - that is, one action opposes another, keeping balance. There are two important forces that we use to control sleep: our sleep drive and our alerting signal. As the day goes on, the drive to sleep becomes greater and greater, so our alerting signal has to increase at the same rate to keep us awake. S........ Read more »
Porkka-Heiskanen T, Strecker RE, & McCarley RW. (2000) Brain site-specificity of extracellular adenosine concentration changes during sleep deprivation and spontaneous sleep: an in vivo microdialysis study. Neuroscience, 99(3), 507-17. PMID: 11029542
People with chronic pain present a special risk for surgeons, anaesthetists, nurses and the rehabilitation team working with them after surgery. Surgery is, after all, “planned trauma”, and a sensitive nervous system is going to be even more sensitive after a surgical insult – even when that surgery is intended to reduce pain.... Read more »
Brummett CM, Janda AM, Schueller CM, Tsodikov A, Morris M, Williams DA, & Clauw DJ. (2013) Survey criteria for fibromyalgia independently predict increased postoperative opioid consumption after lower-extremity joint arthroplasty: a prospective, observational cohort study. Anesthesiology, 119(6), 1434-43. PMID: 24343289
Imagine you are offered a package full of delicious chocolates. Would the size of the pieces of chocolate influences how much you eat?
Yes, it does matter. This blog post is about the unit size effect of indulgent food and why consumers eat less with smaller unit sizes.
... Read more »
van Kleef Ellen, Kavvouris Christos, & van Trijp Hans C.M. (2014) The unit size effect of indulgent food: How eating smaller-sized items signals impulsivity and makes consumers eat less. Psychology , 1-41. DOI: 10.1080/08870446.2014.909426
Anthrax is a deadly disease with high rates of morbidity and mortality. Because it is, thankfully, also quite rare, it is relatively easy to track its whereabouts and going-ons when an outbreak occurs. Typically, outbreaks of anthrax have been traced to groups of people involved in high-risk activities involving grazing animals and their byproducts: anthrax favors shepherds, butchers, wool-sorters, leather workers, and even the odd drum-playing hippies. In 2009, however, an outbreak upended this........ Read more »
Berger, T., Kassirer, M., & Aran, A. (2014) Injectional anthrax - new presentation of an old disease. Eurosurveillance, 19(32), 20877. DOI: 10.2807/1560-7917.ES2014.19.32.20877
Scientists float the idea of introducing male-only prawn stocks to Senegal river to control spread of snails which act as vector for blood flukes... Read more »
Savaya Alkalay, A., Rosen, O., Sokolow, S., Faye, Y., Faye, D., Aflalo, E., Jouanard, N., Zilberg, D., Huttinger, E., & Sagi, A. (2014) The Prawn Macrobrachium vollenhovenii in the Senegal River Basin: Towards Sustainable Restocking of All-Male Populations for Biological Control of Schistosomiasis. PLoS Neglected Tropical Diseases, 8(8). DOI: 10.1371/journal.pntd.0003060
Patients with Birt-Hogg-Dubé (BHD) syndrome usually develop benign hair follicle tumours (BHFTs) which appear as multiple whitish papules developing primarily on the face, neck and torso (Menko et al., 2009). BHFTs such as fibrofolliculomas and trichodiscomas (skin-coloured tumours occurring on the upper body) can be associated with various genetic conditions and their histology is often key to differential diagnosis. The morphology and histology of various BHFTs is discussed in a recent ........ Read more »
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