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  • September 21, 2010
  • 03:41 PM

Agonist-directed trafficking of receptor stimulus, Pharm 551A: Berg et al., 1998


After doing a whole bunch of cutting-edge papers for the class its time to go back in time a bit (like 1998 is ancient but anyways) and do an oldie-but-goodie. This particular paper, “Effector Pathway-Dependent Relative Efficacy at Serotonin Type … Continue reading →... Read more »

  • September 21, 2010
  • 08:00 AM

Why does asbestos cause lung cancer?

by David Bradley in SciScoop Science Forum

When we had some building working work done many years ago, there was a minor scare when one of the builders thought that a panel might be asbestos, thankfully turned out to be some reconstituted wood chip product. But, if it had been asbestos it would have meant us evacuating our home, the recruitment of [...]... Read more »

Liu, G., Beri, R., Mueller, A., & Kamp, D. (2010) Molecular mechanisms of asbestos-induced lung epithelial cell apoptosis. Chemico-Biological Interactions, 188(2), 309-318. DOI: 10.1016/j.cbi.2010.03.047  

  • September 20, 2010
  • 07:49 AM

Power of faces

by Janet Kwasniak in Thoughts on thoughts

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Much of what we know of perception has come from studying illusions. Finding situations were the processes reveal themselves in their ‘mistakes’ give clues to how those processes work under ordinary conditions. Of course, our sensory processes have not actually made a mistake; we have misled them.A new illusion is a [...]... Read more »

Caputo, G. (2010) Strange-face-in-the-mirror illusion. Perception, 39(7), 1007-1008. DOI: 10.1068/p6466  

  • September 19, 2010
  • 08:40 PM

Studying Genes the Ophthalmic Route by MRI, and That too in Living Subjects

by Amiya Kumar Sarkar in Physiology physics woven fine

Modular probes given in eyedrops reach the brain, showing up genes, in disruptions of the blood brain barrier.... Read more »

Liu, C., You, Z., Ren, J., Kim, Y., Eikermann-Haerter, K., & Liu, P. (2007) Noninvasive delivery of gene targeting probes to live brains for transcription MRI. The FASEB Journal, 22(4), 1193-1203. DOI: 10.1096/fj.07-9557com  

  • September 19, 2010
  • 02:37 PM

Do women and men differ in their acceptance of climate warming?

by Phil Camill in Global Change: Intersection of Nature and Culture

In my series on why people don’t engage climate change, we saw major socioeconomic and demographic differences in how people perceive climate change.
In the current issue of Population and Environment, Aaron McCright authors an article, The effects of gender on climate change knowledge and concern in the American public, in which he examines whether women [...]... Read more »

  • September 17, 2010
  • 09:06 AM

Glucosamine chondroitin = FAIL

by David Bradley in SciScoop Science Forum

Glucosamine and chondroitin do not work in alleviating the pain of osteoarthritis (of hip or knee), other than perhaps as an expensive placebo that sufferers who do gain some relief daren’t stop paying for. A new meta analysis of 10 trials amounting to 3803 patients has been carried out. On a 10 cm visual analogue [...]... Read more »

  • September 17, 2010
  • 07:22 AM

Evolution and Costs of Firefly Lights

by Kevin Zelnio in The Online Laboratory of Kevin Zelnio

Photo from Encyclopaedia Britannica.
Light. It’s all around and is the foundation of much of planet. Plants on land or in the shallow seas use the power of light to catalyze a cascade of interactions that ultimately result in the foundation of our planet. Even in the deep sea the products of light find their way [...]... Read more »

  • September 16, 2010
  • 10:29 AM

Identifying novel inhibitors for uncharacterized enzymes, Pharm 551A: Bachovchin et al., 2009


Today is our last paper on high throughput screening (HTS) techniques. We’re back to discovering drugs on this one but the premise is quite different for this particular screen. Whereas other papers we’ve done so far have involved finding novel … Continue reading →... Read more »

  • September 15, 2010
  • 07:04 AM

Going green… literally

by Brian Lambson in Berkeley Science Review Blog

While impressive, the last few decades of human achievement in photovoltaics pale in comparison to nature’s equivalent technology: photosynthesis. Just look at the numbers—every year photosynthesis produces about 3,000 exajoules (EJ) of chemical energy, or 7 x 1017 kilocalories, which equates to about half the total energy stored in the world’s petroleum reserves (and approximately the average daily caloric intake of eating champ Joey Chestnut). Compare this to the 0.1 EJ of electrical en........ Read more »

Sarovar, M., Ishizaki, A., Fleming, G., & Whaley, K. (2010) Quantum entanglement in photosynthetic light-harvesting complexes. Nature Physics, 6(6), 462-467. DOI: 10.1038/nphys1652  

Ham, M.-H., Choi, J. H., Boghossian, A. A., Jeng, E. S., Graff, R. A., Heller, D. A., Chang, A. C., Mattis, A., Bayburt, T. H., Grinkova, Y. V.... (2010) Photoelectrochemical complexes for solar energy conversion that chemically and autonomously regenerate. Nature Chemistry. info:/10.1038/nchem.822

  • September 14, 2010
  • 07:36 PM

Supply Chain Risk Management Dissertations (Process oriented Risk Management of Product Risks)

by Daniel Dumke in SCRM Blog - Supply Chain Risk Management

This is the second contribution to my series on doctoral dissertations on Supply Chain Risk Management. An immense effort and dedication is spent on these works only to find the results hidden in the libraries. So the goal is raise interest in their research.

Author / Topic
This dissertation was written by Jörn Dahmen 2009 as his doctoral thesis at the RWTH, Aachen (one of the most renowned Technical Universities in Germany). It was published by Shaker, Aachen and can be ordered here from........ Read more »

Dahmen, Jörn. (2002) Prozeßorientiertes Risikomanagement zur Handhabung von Produktrisiken. Shaker, Aachen, Dissertation. info:/

  • September 14, 2010
  • 12:46 PM

Relationships get better with age

by eHarmony Labs in eHarmony Labs Blog

Recent studies show that older people have better relationships. What is the secret to their success? ... Read more »

  • September 14, 2010
  • 10:30 AM

Identifying tumor suppressor genes through an in vivo RNA interference screen, Pharm 551A: Bric et al., 2009


On the agenda for today is another paper about screening (one more to go after this one): Bric et al., (2009) Functional identification of tumor-suppressor genes through an in vivo RNA interference screen in a mouse lymphoma model [PMC]. This … Continue reading →... Read more »

  • September 13, 2010
  • 07:13 PM

Finding Truth in a Messy World

by jebyrnes in I'm a chordata, urochordata!

*-note, this was derived from a combination of emails between myself and my former phd advisor. See if you can pick out who is arguing what and where. It’s fun – well, for some of you, anyway. How do we know the world? This is a seemingly simple and vast question – one with no [...]... Read more »

  • September 12, 2010
  • 07:25 PM

Foundation for a Responsive Supply Chain

by Daniel Dumke in SCRM Blog - Supply Chain Risk Management

In the following I summarize the major points of the article "Responsive supply chain: A competitive strategy in a networked economy" by Gunasekaran, Lai and Cheng (2008).

Responsive Supply Chain (RSC)
The authors define a RSC to contain both aspects of Agile Manufacturing and Supply Chain Management. They argue, that both complement each other in the objective to improve organizational competitiveness.

The concept of SCM, Agile manufacturing and RSC can be compared as follows:
Comparison........ Read more »

  • September 11, 2010
  • 04:14 PM

How much would climate change if we used existing infrastructure to the end of its life?

by Phil Camill in Global Change: Intersection of Nature and Culture

Here’s an interesting thought question:  How much would global temperature warm if we used only the existing energy infrastructure (i.e., power plants, furnaces, motor vehicles) until these machines reached the end of their useful lives?  Once they died, they would be replaced by devices that did not emit CO2.
Steven Davis and colleagues addressed this question [...]... Read more »

  • September 10, 2010
  • 10:00 AM

More acupuncture quackademic medicine infiltrates PLoS ONE

by Orac in Respectful Insolence

I hate to do this to Bora again. I really do. I'm also getting tired of blogging all these crappy acupuncture studies. I really am. However, sometimes a skeptic's gotta do what a skeptic's gotta do, and this is one of those times.

As you may recall, a mere week ago I was disturbed to have discovered the publication of a truly horrifically bad acupuncture study in PLoS ONE. It had all the hallmarks of quackademic medicine: an implausible hypothesis, trying to correlate mystical concepts of merid........ Read more »

  • September 8, 2010
  • 02:16 PM

It’s A Waterbird Wasteland

by Journal Watch Online in Journal Watch Online

Maybe sewage could offer salvation. Wetlands built to filter sewage and polluted runoff have become essential habitat for some of the world’s endangered waterbirds, but pose disease risks and other problems. Now, two recent studies offer some insight into the potential conservation promise – and peril – of artificial swamps.
One of the studies, published […] Read More »... Read more »

  • September 8, 2010
  • 08:00 AM

Phantom radiation protection

by sciencebase in Sciencebase Science Blog

Ionizing radiation exists as either subatomic particles (alpha and beta particles, and neutrons) or photons (electromagnetic waves at X-ray and gamma ray wavelengths, i.e. energies of a few electron volts). The energy from such radiation can strip electrons from atoms or molecules, thus ionizing them, but it has to have an energy above a certain [...]Phantom radiation protection is a post from: Sciencebase Science Blog
... Read more »

Mauro Valente, Francisco Malano, & Germán Tirao. (2010) A computational tool for evaluating the exposure risk in nuclear medicine treatments. Int. J. Low Radiation, 7(4), 333-346. info:/

  • September 7, 2010
  • 11:47 PM

The World of Tractography Where The White Matter Tracts Appear Colored

by Amiya Kumar Sarkar in Physiology physics woven fine

White matter tractography, a relatively new MRI based technique, can delineate fiber tracts and assist in surgical planning and research.... Read more »

  • September 7, 2010
  • 08:44 PM

Linking Research and Practice in Science Teaching

by Jack Hassard in The Art of Teaching Science

For many years I was fortunate to conduct seminars for the Bureau of Research in Education (BER), an organization that provides staff development and training resources for educators in North America.  One of the principles that provided the framework for the seminars that I did, and others that the BER offers is the link between [...]

Related posts:Time to Review Online: National Research Council Framework for Science Education
Humanizing Science Teacher Education
Engineering as a Way to Hum........ Read more »

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