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  • September 29, 2014
  • 08:52 PM
  • 33 views

There's nothing quite like renewables: Modeling indicates natural gas production will not reduce future greenhouse gas emissions as hoped

by Jonathan Trinastic in Goodnight Earth

Not so fast natural gas! New modeling using 'commitment' accounting to represent social inertia indicates that natural gas may not reduce emissions as hoped.... Read more »

Steven J Davis and Robert H Socolow. (2014) Commitment accounting of CO2 emissions. Environmental Research Letters, 9(084018). info:/

  • September 29, 2014
  • 06:07 PM
  • 37 views

Cat and Dogs: seeking solutions with sniffing canines and science

by Cobb & Hecht in Do You Believe In Dog?

Hi Mia and Julie,  First of all, I LOVE your blog! After meeting at SPARCS this past summer (summer for us in North America.. I take it summer is just beginning in Australia!), I’ve followed it closely.  You do amazing things for the promotion of  canine science. Serious love. A bit of background for the readers: I’m currently doing my PhD at Dalhousie University in Halifax, Nova Scotia in Canada, under the supervision of Dr. Simon Gadbois. Dr. Gadbois........ Read more »

  • September 29, 2014
  • 05:12 PM
  • 30 views

New Protein Implicated in Alzheimer’s

by Gabriel in Lunatic Laboratories

Alzheimer's prevention has made some strides in recent years. We've even identified some new causes, and in some cases we can do both. In fact, researchers have now shown that low levels of the protein progranulin in the brain can increase the formation of amyloid-beta plaques (a hallmark of Alzheimer's disease). These plaques can cause neuroinflammation, and worsen memory deficits in a mouse model of this condition. Conversely, by using a gene therapy approach to elevate progranulin levels, sci........ Read more »

Minami, S., Min, S., Krabbe, G., Wang, C., Zhou, Y., Asgarov, R., Li, Y., Martens, L., Elia, L., Ward, M.... (2014) Progranulin protects against amyloid β deposition and toxicity in Alzheimer's disease mouse models. Nature Medicine. DOI: 10.1038/nm.3672  

  • September 28, 2014
  • 03:37 PM
  • 61 views

The Genetic Evolutionary Arms Race

by Gabriel in Lunatic Laboratories

Genes are tricky little buggers, the stuff that makes us up has fought the test of time to make it to where we are today. It is thought that our genes changed in an attempt to outpace other life, albeit random changes.That might only be half right however, new findings suggest that there is an evolutionary arms race going on within the genome against, of all things, itself. This inherent competition of primates drove the evolution of complex regulatory networks that orchestrate the activity of ........ Read more »

Jacobs, Greenberg, Nguyen, Haeussler, Ewing, Katzman, Paten, Salama . (2014) An evolutionary arms race betweenKRAB zinc-finger genes ZNF91/93 and SVA/L1 retrotransposons. Nature. info:/10.1038/nature13760

  • September 27, 2014
  • 01:29 PM
  • 82 views

Are Black Holes just in Our Imagination?!

by Gabriel in Lunatic Laboratories

Black holes, physicists have been fighting over them forever, heck there is even a book entitled the black hole war! (which I do recommend for anyone interested) It’s no real surprise since they are the ultimate unknown – the blackest and most dense objects in the universe that do not even let light escape. And as if they weren't bizarre enough to begin with, now add this to the mix: they don’t exist.... Read more »

Laura Mersini-Houghton, Harald P. Pfeiffer. (2014) Back-reaction of the Hawking radiation flux on a gravitationally collapsing star II: Fireworks instead of firewalls . Physics Letters B. info:/arXiv:1409.1837

  • September 26, 2014
  • 02:15 PM
  • 98 views

“GMO” Foods (Once Again) Proven Safe

by Gabriel in Lunatic Laboratories

GMO, I shudder every time I hear someone talk about the “dangers”. It’s one of the new buzzwords that doesn’t actually mean anything, but still manages to scare people. Well a new scientific review reports that the performance and health of food-producing animals consuming genetically engineered feed, first introduced 18 years ago, has been comparable to that of animals consuming non-GE feed. Not that this will stop people from spreading fear, but it’s a start.... Read more »

  • September 25, 2014
  • 10:37 AM
  • 105 views

A New Discovery in the Treatment of Autoimmunity and Chronic Inflammation

by Gabriel in Lunatic Laboratories

Lupus, Type 1 diabetes, and multiple sclerosis are all diseases brought on by autoimmunity — the bodies inability to tell itself apart from foreign invaders. Finding a cure, or even a suitable treatment has been to put it gently a long, painful road, with little to show for it. On the forefront of the war against the body betrayal is immunosuppressants, which with them carry their own set of side effects and in most cases only off mild to moderate relief of symptoms. But that is all changing a........ Read more »

Dubiella C, Cui H, Gersch M, Brouwer AJ, Sieber SA, Krüger A, Liskamp RM, & Groll M. (2014) Selective Inhibition of the Immunoproteasome by Ligand-Induced Crosslinking of the Active Site. Angewandte Chemie (International ed. in English). PMID: 25244435  

  • September 24, 2014
  • 03:54 PM
  • 79 views

A new Medicine may help Lupus Sufferers

by Gabriel in Lunatic Laboratories

Lupus, a particularly bad hell on earth for people suffering from it. Lupus is caused by autoimmunity, in where the body attacks itself. I have a special place in my heart for people suffering from the disease because my Uncle suffered from it. There is no cure and only moderately effective treatments for the disorder, which causes, in some cases, the most excruciating pain you will ever feel. Thankfully new findings by a biomedical engineering team raise hope for a new class of drugs to treat l........ Read more »

  • September 24, 2014
  • 11:42 AM
  • 76 views

Genetics "Experts" Surveyed on Returning Incidental Findings

by Daniel Koboldt in Massgenomics

In my last post, I wrote about the return of results from next-gen sequencing, specifically a recent paper in AJHG about secondary findings in ~6500 ESP exomes. Today we’ll delve into another paper in the same issue on the attitudes of genetics professionals on return of incidental findings from whole genome sequencing (WGS) and exome sequencing […]... Read more »

  • September 23, 2014
  • 06:41 PM
  • 60 views

A shale's life: first life cycle assessment of shale gas production in Great Britain

by Jonathan Trinastic in Goodnight Earth

A paper has just come out looking at the life cycle impact of shale gas production in Great Britain. At the same time, the author is speaking at the Labour Party Conference in Manchester. A great opportunity for science and policy to unite!... Read more »

  • September 23, 2014
  • 01:55 PM
  • 84 views

Lie Detection using Brain Waves: It’s just as creepy as it sounds…

by Gabriel in Lunatic Laboratories

Currently lie detectors (polygraphs) are not admissible in court, this is because (despite what you may read) there is little proof to show that they are much better than a guess — coming in at roughly 50% accuracy. They aren’t really based in science, making them more of a toy. There might just be a new contender in the lie detection department coming soon however, researchers have found that brain activity can be used to tell whether someone recognizes details they encountered in normal, d........ Read more »

  • September 22, 2014
  • 02:17 PM
  • 77 views

Autism and the Low Iron Connection

by Gabriel in Lunatic Laboratories

The topic of autism is a charged one. Maybe it’s because it isn’t a simple diagnosis; there are many roads to autism. Most of them are probably genetic, some of them are likely environmental, and none of them are related to vaccination (sorry to burst your bubble anti vax people, it’s called science). Some new research shows another possible (environmental) cause. The new study shows that mothers of children with autism are significantly less likely to report taking iron supplements before........ Read more »

Rebecca J. Schmidt et al. (2014) Maternal intake of supplemental iron and risk for autism spectrum disorders. American Journal of Epidemiology. info:/

  • September 21, 2014
  • 02:33 PM
  • 80 views

Move over Carbon nanotubes introducing Diamond nanothreads

by Gabriel in Lunatic Laboratories

Carbon nanotubes, the wave of the future. Our hopes and dreams for the future have been firmly placed in using the unique material for everything from electronics to engineering. Unfortunately the production of carbon nanotubes has been hampered by setbacks, which as it turns out might not be a bad thing. This is because for the first time, scientists have discovered how to produce ultra-thin “diamond nanothreads” that promise extraordinary properties, including strength and stiffness greate........ Read more »

Fitzgibbons, T., Guthrie, M., Xu, E., Crespi, V., Davidowski, S., Cody, G., Alem, N., & Badding, J. (2014) Benzene-derived carbon nanothreads. Nature Materials. DOI: 10.1038/nmat4088  

  • September 20, 2014
  • 03:43 PM
  • 108 views

Lengthen Telomeres and Turn Back Aging

by Gabriel in Lunatic Laboratories

Want to live longer and healthier? Of course you do, well science may just have the answer! Scientists have discovered an on-and-off "switch" in cells that may hold the key to healthy aging. This switch points to a way to encourage healthy cells to keep dividing and generating, for example, new lung or liver tissue, even in old age. Getting cells to divide might not be that hard (or even very useful), but that isn't all, it gets better!... Read more »

  • September 20, 2014
  • 01:52 PM
  • 81 views

Solving the metal problem: new organic solar cell material allows wide use of metal cathodes, improves efficiency

by Jonathan Trinastic in Goodnight Earth

New research in Science shows the use of a new organic buffer layer that allows a wide range of metal electrodes to be used in conjunction with solution-based processing.... Read more »

  • September 19, 2014
  • 07:28 PM
  • 89 views

Nanosponges Clean up Antibody-mediated Autoimmune Disease

by Gabriel in Lunatic Laboratories

What does lupus, rheumatoid arthritis, type I diabetes, multiple sclerosis, and rheumatic heart disease have in common? All of these (and many other) apparently unrelated disorders are caused by autoimmunity, in which the immune system produces antibodies that attack normal, healthy cells and tissues. Currently considered incurable, these autoimmune diseases can be managed, but to varying degrees and not without serious side effects. Moreover, autoimmune diseases include a wide range of dysfunct........ Read more »

Copp JA, Fang RH, Luk BT, Hu CM, Gao W, Zhang K, & Zhang L. (2014) Clearance of pathological antibodies using biomimetic nanoparticles. Proceedings of the National Academy of Sciences of the United States of America, 111(37), 13481-6. PMID: 25197051  

  • September 19, 2014
  • 01:21 PM
  • 110 views

New test for Diagnosing Alzheimer’s Early

by Gabriel in Lunatic Laboratories

Alzheimer’s diagnosis is important, like the famous slogan “with a stroke, time lost is brain lost,” detecting alzheimer’s is important in order to stave off cognitive decline. A just like a stroke time lost is brain lost. Unfortunately early diagnosis has been hard to come by, but now researchers say a simple test that combines thinking and movement can help to detect heightened risk for developing Alzheimer’s disease in a person. The best part, they say this will work even before the........ Read more »

  • September 18, 2014
  • 12:58 PM
  • 123 views

Is Stress Eating Away at You? No, Literally…

by Gabriel in Lunatic Laboratories

Ever wonder why, when people are too stressed, they are often grouchy, grumpy, nasty, distracted or forgetful? It may not be something you’ve done, in fact it turns out stress is literally tearing apart the brain. By this I mean that researchers have just highlighted a fundamental synaptic mechanism that explains the relationship between chronic stress and the loss of social skills and cognitive impairment. When triggered by stress, an enzyme attacks a synaptic regulatory molecule in the brain........ Read more »

van der Kooij, M., Fantin, M., Rejmak, E., Grosse, J., Zanoletti, O., Fournier, C., Ganguly, K., Kalita, K., Kaczmarek, L., & Sandi, C. (2014) Role for MMP-9 in stress-induced downregulation of nectin-3 in hippocampal CA1 and associated behavioural alterations. Nature Communications, 4995. DOI: 10.1038/ncomms5995  

  • September 17, 2014
  • 05:56 PM
  • 153 views

Why are ethical standards higher in science than in business and media?

by Richard Kunert in Brain's Idea

Facebook manipulates user content in the name of science? Scandalous! It manipulates user content in the name of profit? No worries! Want to run a Milgram study these days? Get bashed by your local ethics committee! Want to show it on TV? No worries. Why do projects which seek knowledge have higher ethical standards than […]... Read more »

Kramer AD, Guillory JE, & Hancock JT. (2014) Experimental evidence of massive-scale emotional contagion through social networks. Proceedings of the National Academy of Sciences of the United States of America, 111(24), 8788-90. PMID: 24889601  

Milgram, S. (1963) Behavioral Study of obedience. The Journal of Abnormal and Social Psychology, 67(4), 371-378. info:/doi: 10.1037/h0040525

  • September 17, 2014
  • 01:24 PM
  • 93 views

Biofilms: Using Bacteria for new Designer Nanomaterials

by Gabriel in Lunatic Laboratories

For most people biofilms conjure up images of slippery stones in a streambed and dirty drains. While there are plenty of "bad" biofilms around – they are even the same stuff that causes pesky dental plaque and a host of other more serious medical problems – a team of researchers sees biofilms as a robust new platform for designer nanomaterials that could clean up polluted rivers, manufacture pharmaceutical products, fabricate new textiles, and more.... Read more »

Peter Q. Nguyen,, Zsofia Botyanszki,, Pei Kun R. Tay,, & Neel S. Joshi. (2014) Programmable biofilm-based materials from engineered curli nanofibres. Nature Communications. info:/10.1038/ncomms5945

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