Okay, not quite all of them. But it looks like Misha Ahrens and Jeremy Freeman are going to continue their reign of terror, imaging the whole zebrafish brain as if it’s no big deal. Yeah they’ve got almost every neuron of a vertebrate, so what? Besides figuring out that not shooting light at the eyes might […]... Read more »
Freeman, J., Vladimirov, N., Kawashima, T., Mu, Y., Sofroniew, N., Bennett, D., Rosen, J., Yang, C., Looger, L., & Ahrens, M. (2014) Mapping brain activity at scale with cluster computing. Nature Methods. DOI: 10.1038/nmeth.3041
Vladimirov, N., Mu, Y., Kawashima, T., Bennett, D., Yang, C., Looger, L., Keller, P., Freeman, J., & Ahrens, M. (2014) Light-sheet functional imaging in fictively behaving zebrafish. Nature Methods. DOI: 10.1038/nmeth.3040
Possibly one of the most famous cases of parkinson’s is Michael J. Fox. More than just the “shakes” parkinson’s can cause a whole host of other problems mentally and physically […]... Read more »
Barnum CJ, Chen X, Chung J, Chang J, Williams M, Grigoryan N, Tesi RJ, & Tansey MG. (2014) Peripheral Administration of the Selective Inhibitor of Soluble Tumor Necrosis Factor (TNF) XPro1595 Attenuates Nigral Cell Loss and Glial Activation in 6-OHDA Hemiparkinsonian Rats. Journal of Parkinson's disease. PMID: 25061061
Despite all the efforts, people are losing the war on obesity. There is probably a number of factors involved, genetics, underlying medical problems, most of all diet, but in any […]... Read more »
Williams KW, Liu T, Kong X, Fukuda M, Deng Y, Berglund ED, Deng Z, Gao Y, Liu T, Sohn JW.... (2014) Xbp1s in Pomc Neurons Connects ER Stress with Energy Balance and Glucose Homeostasis. Cell metabolism. PMID: 25017942
Five of the coolest news stories from the past week... Read more »
Koubeissi, M., Bartolomei, F., Beltagy, A., & Picard, F. (2014) Electrical stimulation of a small brain area reversibly disrupts consciousness. Epilepsy , 32-35. DOI: 10.1016/j.yebeh.2014.05.027
Sleep disturbance following traumatic brain injury (TBI) is a common clinical challenge.Hypersomnia and insomnia can both been seen in the TBI population.The risk factors related to TBI-related sleep disturbance are not well known. Identification of risk factors can provide insight into clinical assessment and management.Lijun Hou and colleagues recently examined risk factors related to subjective sleep complaints in a series of 98 TBI subjects.The study sample include adults admitted to a ........ Read more »
Hou L, Han X, Sheng P, Tong W, Li Z, Xu D, Yu M, Huang L, Zhao Z, Lu Y.... (2013) Risk factors associated with sleep disturbance following traumatic brain injury: clinical findings and questionnaire based study. PloS one, 8(10). PMID: 24098425
The American Bar Association is seeking nominations until August 8, 2014 to help it decide on the Top 100 law blogs (“Blawgs”). We have been in the ABA Top 100 for the past 4 years and would like to make it 5! If you like this blog, please nominate us (it’s fast and free) here. […]
A new issue of The Jury Expert!
Who cares? The crime victim was old anyway!
“I punish you because you harmed him!”
... Read more »
Shariff AF, Greene JD, Karremans JC, Luguri JB, Clark CJ, Schooler JW, Baumeister RF, & Vohs KD. (2014) Free Will and Punishment: A Mechanistic View of Human Nature Reduces Retribution. Psychological science. PMID: 24916083
Where are they?
Close-up view of the meninges surrounding the brain.
The term meninges comes from the Greek for "membrane" and refers to the three membranes that surround the brain and spinal cord. The membrane layers (discussed in detail below) from the outside in are the: dura mater, arachnoid mater, and pia mater. Their positioning around the brain can be seen in the image to the right.What are they and what do they do?The brain is s........ Read more »
Fish might not be the first thing you think about when we talk spinal cord injury but that is exactly what scientists are doing. Don’t ask where they got the […]... Read more »
Lewandowski, G., & Steward, O. (2014) AAVshRNA-Mediated Suppression of PTEN in Adult Rats in Combination with Salmon Fibrin Administration Enables Regenerative Growth of Corticospinal Axons and Enhances Recovery of Voluntary Motor Function after Cervical Spinal Cord Injury. Journal of Neuroscience, 34(30), 9951-9962. DOI: 10.1523/JNEUROSCI.1996-14.2014
I am a neuroscientist, and as a neuroscientist I have a strange belief that most of who we are comes from our brains. My entire career is based around understanding behavior from this neural level which I feel to be fairly justifiable. So when I see paper looking at the genetics of behavior, I expect to see at […]... Read more »
Ripke, S., Neale, B., Corvin, A., Walters, J., Farh, K., Holmans, P., Lee, P., Bulik-Sullivan, B., Collier, D., Huang, H.... (2014) Biological insights from 108 schizophrenia-associated genetic loci. Nature, 511(7510), 421-427. DOI: 10.1038/nature13595
Coming from a, to put it gently, very broken home, my babysitter was the television. Yep, so now that you are feeling nice and awkward let’s talk television. New research, […]... Read more »
Linebarger DL, Barr R, Lapierre MA, & Piotrowski JT. (2014) Associations Between Parenting, Media Use, Cumulative Risk, and Children's Executive Functioning. Journal of developmental and behavioral pediatrics : JDBP, 35(6), 367-77. PMID: 25007059
When you look at the edge of a table, there is a neuron in your head that goes from silence to pop pop pop. As you extend your arm, a nerve commanding the muscle does the same thing. Your retina has neurons whose firing rate goes up or down depending on whether it detects a light spot […]... Read more »
Kaufman MT, Churchland MM, Ryu SI, & Shenoy KV. (2014) Cortical activity in the null space: permitting preparation without movement. Nature neuroscience, 17(3), 440-8. PMID: 24487233
Mante V, Sussillo D, Shenoy KV, & Newsome WT. (2013) Context-dependent computation by recurrent dynamics in prefrontal cortex. Nature, 503(7474), 78-84. PMID: 24201281
Shenoy KV, Sahani M, & Churchland MM. (2013) Cortical control of arm movements: a dynamical systems perspective. Annual review of neuroscience, 337-59. PMID: 23725001
Ames KC, Ryu SI, & Shenoy KV. (2014) Neural dynamics of reaching following incorrect or absent motor preparation. Neuron, 81(2), 438-51. PMID: 24462104
Churchland, M., Cunningham, J., Kaufman, M., Ryu, S., & Shenoy, K. (2010) Cortical Preparatory Activity: Representation of Movement or First Cog in a Dynamical Machine?. Neuron, 68(3), 387-400. DOI: 10.1016/j.neuron.2010.09.015
My friend has a glass eye, you would never notice and unless you knew the story you might not think anything of it. His older brother did it. Yes, you […]... Read more »
Dana Goldman,, John Fastenau,, Riad Dirani,, Eric Hellend,, Geoff Joyce,, Ryan Conrad,, & Darius Lakdawalla,. (2014) Medicaid Prior Authorization Policies and Imprisonment Among Patients With Schizophrenia. The American Journal of Managed Care, 20(7). info:/2014;20(7):577-586
Raising an autistic child can be a gift. Unfortunately it can also be challenging and stressful. Let’s be real, it’s stressful just being a parent, throw in a disability that […]... Read more »
Dykens Elisabeth M. , & Fisher Marisa H. . (2014) Reducing Distress in Mothers of Children With Autism and Other Disabilities: A Randomized Trial. Pediatrics . DOI: 10.1542/peds.2013-3164
The brain is complex, heck if it wasn’t then we wouldn’t be smart enough to figure out how it works. I guess it’s one of those stupid catch-22 type things. […]... Read more »
Yamada, T., Yang, Y., Hemberg, M., Yoshida, T., Cho, H., Murphy, J., Fioravante, D., Regehr, W., Gygi, S., Georgopoulos, K.... (2014) Promoter Decommissioning by the NuRD Chromatin Remodeling Complex Triggers Synaptic Connectivity in the Mammalian Brain. Neuron, 83(1), 122-134. DOI: 10.1016/j.neuron.2014.05.039
At first glance the title might sound a little weird. But if that is the case then you probably want to read this. Researchers have identified a group of cells in […]... Read more »
Chen, C., Jiang, P., Xue, H., Peterson, S., Tran, H., McCann, A., Parast, M., Li, S., Pleasure, D., Laurent, L.... (2014) Role of astroglia in Down’s syndrome revealed by patient-derived human-induced pluripotent stem cells. Nature Communications. DOI: 10.1038/ncomms5430
A recent study by Karel Kleisner et al. (2013) shows eye colour and facial features have an influence on our perception of trustworthiness.... Read more »
It appears that certain personality traits and traumatic early life events are typically associated with binge drinking in teenage years. However, the predictive power of each type of factors by itself (personality or individual history for example) is not absolute. A new study evaluated not only one single factor, but a series of psychological, genetic, and neurological elements for their ability to determine, when combined, current and future alcohol misuse in a large group of youngsters. ... Read more »
Whelan, R., Watts, R., Orr, C., Althoff, R., Artiges, E., Banaschewski, T., Barker, G., Bokde, A., Büchel, C., Carvalho, F.... (2014) Neuropsychosocial profiles of current and future adolescent alcohol misusers. Nature. DOI: 10.1038/nature13402
The Mediterranean diet, it may have broad health benefits [let's face it we can't seem to escape the push for it here in the US], but a new study suggests that […]... Read more »
Koyama, A., Houston, D., Simonsick, E., Lee, J., Ayonayon, H., Shahar, D., Rosano, C., Satterfield, S., & Yaffe, K. (2014) Association Between the Mediterranean Diet and Cognitive Decline in a Biracial Population. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences. DOI: 10.1093/gerona/glu097
Where is it?
Thalamus (in red).
The thalamus is a large, symmetrical (meaning there is one in each hemisphere) structure that makes up most of the mass of the diencephalon. A large number of pathways travel through the thalamus, including all of the sensory pathways other than those devoted to olfaction (smell).What is it and what does it do?The thalamus is often described as a relay station. This is because almost all sensory informati........ Read more »
Sherman, S., & Guillery, R. (2002) The role of the thalamus in the flow of information to the cortex. Philosophical Transactions of the Royal Society B: Biological Sciences, 357(1428), 1695-1708. DOI: 10.1098/rstb.2002.1161
The Max Planck Institute in Nijmegen has started a great initiative which tries nothing less than answer all your questions about language. How does it work? 1) Go to this website: http://www.mpi.nl/q-a/questions-and-answers 2) See whether your question has already been answered 3) If not, scroll to the bottom and ask a question yourself. The answers […]... Read more »
Thibodeau, P., & Boroditsky, L. (2011) Metaphors We Think With: The Role of Metaphor in Reasoning. PLoS ONE, 6(2). DOI: 10.1371/journal.pone.0016782
Asaridou, S., & McQueen, J. (2013) Speech and music shape the listening brain: evidence for shared domain-general mechanisms. Frontiers in Psychology. DOI: 10.3389/fpsyg.2013.00321
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