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  • January 28, 2015
  • 08:21 PM
  • 3 views

Negative Patient-Doctor Communication More Powerful Than Positive Interaction

by Marie Benz in MedicalResearch.com

MedicalResearch.com Medical Research Interviews and News
MedicalResearch.com Interview with: Dr Maddy Greville-Harris Research Fellow University of Southampton   Medical Research: What is the background for this study? What are the main findings? Dr. Greville-Harris: Our research looks at the effects of non-understanding feedback (‘invalidation’) and discusses … Continue reading →
The post Negative Patient-Doctor Communication More Powerful Than Positive Interaction........ Read more »

MedicalResearch.com Interview with, Dr Maddy Greville-Harris, Research Fellow, & University of Southampton. (2015) Negative Patient-Doctor Communication More Powerful Than Positive Communication . MedicalResearch.com. info:/

  • January 28, 2015
  • 03:08 PM
  • 17 views

Everyday chemical exposure leads to early menopause

by Dr. Jekyll in Lunatic Laboratories

Seems like everything is killing us these days. Well ladies, you have one more thing that is causing you problems. New research has shown that women whose bodies have high levels of chemicals found in plastics, personal-care products, common household items and the environment experience menopause two to four years earlier than women with lower levels of these chemicals.... Read more »

Grindler, N., Allsworth, J., Macones, G., Kannan, K., Roehl, K., & Cooper, A. (2015) Persistent Organic Pollutants and Early Menopause in U.S. Women. PLOS ONE, 10(1). DOI: 10.1371/journal.pone.0116057  

  • January 28, 2015
  • 08:00 AM
  • 26 views

Crawling To The Top

by Mark Lasbury in As Many Exceptions As Rules

Nematodes cause horrible diseases, but they way they reproduce is the most fascinating thing about them. Their sperm aren’t shaped like typical animal male gametes. They crawl instead of swimming, and they have a type of cytoskeleton not seen in any other cell type on Earth. Yet, the nematode is the most numerous type of animal on Earth.... Read more »

Smith HE. (2014) Nematode sperm motility. WormBook : the online review of C. elegans biology, 1-15. PMID: 24715710  

H. Ferris. (2009) The beer mat nematode, Panagrellus The beer mat nematode, Panagrellus redivivus: A study of the connectedness of scientific discovery . J. Nematode Morphol. Syst., 12(1), 19-25. info:/

McKnight, K., Hoang, H., Prasain, J., Brown, N., Vibbert, J., Hollister, K., Moore, R., Ragains, J., Reese, J., & Miller, M. (2014) Neurosensory Perception of Environmental Cues Modulates Sperm Motility Critical for Fertilization. Science, 344(6185), 754-757. DOI: 10.1126/science.1250598  

  • January 28, 2015
  • 05:03 AM
  • 27 views

Urinary histidine as a marker of 'dioxin-induced' neurodevelopmental issues?

by Paul Whiteley in Questioning Answers

The paper by Muneko Nishijo and colleagues [1] (open-access) caught my eye recently and their continuing investigations into the potential effects of perinatal dioxin exposure on offspring neurodevelopmental outcomes. For a bit of background on this initiative based in Vietnam, I would refer readers to a previous post on this blog (see here).Your weakness is copper? Y-you're kidding right?In case you can't be bothered to follow that previous link, the idea was that exposure to TCDD [2,........ Read more »

  • January 27, 2015
  • 01:55 PM
  • 36 views

Your brain is hardening your arteries, but not on purpose!

by Dr. Jekyll in Lunatic Laboratories

Your brain might just be killing you slowly. Atherosclerosis — or hardening and narrowing of the arteries — can be caused by fat buildup that causes plaque deposits, and is one of the main causes of cardiovascular disease. What does that have to do with the brain? Well new research has shown a link between how the brain regulates fat metabolism, which has the potential of stopping the development of this disease risk factor in obesity and diabetes.... Read more »

  • January 27, 2015
  • 07:30 AM
  • 33 views

Star Date: Pretty Darn Soon

by Mark E. Lasbury in The 'Scope

Star Trek celebrates its 50th anniversary in 2016. In preparation for the celebrations, we’re checking in on how close we are to making Star Trek technology a reality. The replicator made food and recycled trash, and later was used to make parts for the Enterprise. A machine fabricated what they needed on the spot. We have that now on the space station! Do you know how 3-D printing works and how we print parts, food, and even living tissue? Here’s how.... Read more »

  • January 27, 2015
  • 04:33 AM
  • 32 views

Siblings, genetics and the autisms (plural)

by Paul Whiteley in Questioning Answers

The paper by Ryan Yuen and colleagues [1] suggesting that most siblings with autism do not share the same genetic variations thought to contribute to the condition has garnered quite a few media headlines of late (see here and see here).Applying the concept of whole-genome sequencing whereby the complete genetic blueprint of a person is mapped to provide "the most comprehensive collection of an individual's genetic variation" [2], 340 genomes from 85 families with two children with a d........ Read more »

Yuen, R., Thiruvahindrapuram, B., Merico, D., Walker, S., Tammimies, K., Hoang, N., Chrysler, C., Nalpathamkalam, T., Pellecchia, G., Liu, Y.... (2015) Whole-genome sequencing of quartet families with autism spectrum disorder. Nature Medicine. DOI: 10.1038/nm.3792  

  • January 26, 2015
  • 09:21 PM
  • 30 views

High-Dose Statin May Protect Heart Surgery Patients’ Kidney Health

by Wiley Asia Blog in Wiley Asia Blog - Health Sciences

Acute kidney injury often arises after major surgery because the kidneys can be deprived of normal blood flow during the procedure. The use of contrast media, or dyes, can contribute to this problem. In patients undergoing coronary angiography or percutaneous coronary intervention, which are heart procedures that use dyes to help surgeons visualize the arteries, a high dose of the statin atorvastatin was linked with a reduction in blood levels of creatinine, a marker of kidney injury, as well as........ Read more »

  • January 26, 2015
  • 05:36 PM
  • 52 views

You can’t unboil an egg? Well… now you can

by Dr. Jekyll in Lunatic Laboratories

There is a saying, “you can’t unboil an egg.” Usually this is just illustrating cause and effect; you can’t turn back time, or what’s done is done. Well now scientists have successfully unboiled an egg, so suck it thermodynamics. An international team of chemists have accomplished this feat – an innovation that could dramatically reduce costs for cancer treatments, food production and other segments of the $160 billion global biotechnology industry, according to the findings.... Read more »

Yuan, T., Ormonde, C., Kudlacek, S., Kunche, S., Smith, J., Brown, W., Pugliese, K., Olsen, T., Iftikhar, M., Raston, C.... (2015) Shear-Stress-Mediated Refolding of Proteins from Aggregates and Inclusion Bodies. ChemBioChem. DOI: 10.1002/cbic.201402427  

  • January 26, 2015
  • 04:32 PM
  • 51 views

The secret for a longer life? Kill your unfit cells

by Isabel Torres in Science in the clouds

If you had the choice, would you like to live until you’re 130 years old? New research in fruit flies shows that manipulating a single gene can extend their lifespan up to 60%, suggesting that living well into your hundreds might become a reality in the foreseeable future.Dying of old age is a strange thing. Why does our health decline just because we’re old? Although the answer might at first seem obvious or simple, it really isn’t. There are countless theories of ageing, a few popular ev........ Read more »

  • January 26, 2015
  • 06:23 AM
  • 62 views

Is it necessary to use brain imaging to understand teen girls' sexual decision making?

by The Neurocritic in The Neurocritic

“It is feasible to recruit and retain a cohort of female participants to perform a functional magnetic resonance imaging [fMRI] task focused on making decisions about sex, on the basis of varying levels of hypothetical sexual risk, and to complete longitudinal prospective diaries following this task. Preliminary evidence suggests that risk level differentially impacts brain activity related to sexual decision making in these women [i.e., girls aged 14-15 yrs], which may be related to pas........ Read more »

  • January 26, 2015
  • 04:44 AM
  • 53 views

What factors are linked to behavioural crises in autism?

by Paul Whiteley in Questioning Answers

The question posed in the title of this post was asked and [partly] answered by the paper by Vincent Guinchat and colleagues [1] based on the analysis of 58 adolescents diagnosed with an autism spectrum disorder (ASD) and "hospitalized for severe challenging behaviors." Challenging behaviours, by the way, refers to a whole spectrum of presentations which doesn't just include aggressive or violent behaviours (see here). Indeed, I recently talked about irritability and autism (see here), whic........ Read more »

  • January 24, 2015
  • 01:39 PM
  • 82 views

Lucid dreaming: The similarities between dreaming and wakefulness

by Dr. Jekyll in Lunatic Laboratories

To control one’s dreams and to live out there what is impossible in real life — a truly tempting idea. Some people — so-called lucid dreamers — can do this. Researchers have discovered that the brain area which enables self-reflection is larger in lucid dreamers. Thus, lucid dreamers are possibly also more self-reflecting when they are awake.... Read more »

Filevich E, Dresler M, Brick TR, & Kühn S. (2015) Metacognitive mechanisms underlying lucid dreaming. The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(3), 1082-8. PMID: 25609624  

  • January 24, 2015
  • 05:34 AM
  • 64 views

Hartnup disease in coeliac disease: lessons for 'some' autism?

by Paul Whiteley in Questioning Answers

The paper by Thomas Ciecierega and colleagues [1] (open-access) talking about 'refractory' coeliac disease (CD) - a lack of, or diminished response to a gluten-free diet (the primary management option for CD) - and the subsequent diagnosis of Hartnup disease in a young girl is fodder for today's brief post.I already had a big bowl of curly-toed weirdo for breakfast.Describing how authors first diagnosed her with CD but witnessed "only mild clinical and laboratory improvement"........ Read more »

  • January 23, 2015
  • 03:25 PM
  • 80 views

Exotic Pets: Emerging Risk Factor for Salmonellosis in Children

by Pranab Chatterjee in Scepticemia

The increasing trend of having exotic reptiles as pets may lead to an increase in reptile associated infections such as Salmonellosis, especially in the children in the household. ... Read more »

  • January 23, 2015
  • 01:53 PM
  • 74 views

First Partially Successful Vaccine Developed Against Prion Disease in Deer

by Pranab Chatterjee in Scepticemia

The first partially successful vaccine against a prion disease (Chronic Wasting Disease in white tailed deer) is good news, but the journey has just begun. ... Read more »

  • January 23, 2015
  • 06:30 AM
  • 70 views

NAC risperidone = decreased irritability in autism?

by Paul Whiteley in Questioning Answers

It's been a while since I talked about NAC - N-acetylcysteine - on this blog with either autism or schizophrenia in mind (see here and see here respectively). Today I'm going to remedy that situation by bringing the paper by Nikoo and colleagues [1] to your attention, and their observation: "N-acetylcysteine can be considered as an adjuvant therapy for ADs [autistic disorders] with beneficial therapeutic outcomes." Adjuvant therapy by the way, refers to a sort of add-on therapy.We have........ Read more »

  • January 22, 2015
  • 05:50 PM
  • 164 views

Belief’s effect on biochemistry in cases of addiction

by Dr. Jekyll in Lunatic Laboratories

Ever wonder what makes people susceptible to addiction? Think about it, some people can stop addictive painkillers without a problem and others, well others are not so lucky. So the big question is are there more than biophysical factors at play in addiction? A new study shows that cognitive beliefs play a significant role in a person’s neurological response to an addictive substance and that belief can diminish the neurological effects of an addictive drug.... Read more »

Gu, X., Lohrenz, T., Salas, R., Baldwin, P., Soltani, A., Kirk, U., Cinciripini, P., & Montague, P. (2015) Belief about nicotine selectively modulates value and reward prediction error signals in smokers. Proceedings of the National Academy of Sciences, 201416639. DOI: 10.1073/pnas.1416639112  

  • January 22, 2015
  • 02:06 PM
  • 80 views

Black Tar Heroin: Lower HIV Transmission vs Higher Bacterial Infections?

by Pranab Chatterjee in Scepticemia

The rise of street-cut, unsanitary preparations of Black Tar Heroin has allegedly reduced HIV transmission but at the cost of higher numbers of fatal, bacterial infections, notably botulism, clusters of which have been regularly identified in California.... Read more »

  • January 22, 2015
  • 01:45 PM
  • 80 views

Modeling an epidemic to help guide public health policies (Ebola, West Africa)

by Aurelie in Coffee break Science

By mid-December 2014, about 18,000 individuals had been reported to be infected by the Ebola virus currently causing an epidemic in West Africa. On January 12, 2015, the World Health Organization’s (WHO) latest report stated an updated total of more … Continue reading →... Read more »

Drake JM, Kaul RB, Alexander LW, O'Regan SM, Kramer AM, Pulliam JT, Ferrari MJ, & Park AW. (2015) Ebola cases and health system demand in liberia. PLoS biology, 13(1). PMID: 25585384  

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