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  • August 29, 2015
  • 01:48 PM
  • 24 views

Confidence in parenting could help break cycle of abuse

by Dr. Jekyll in Lunatic Laboratories

To understand how confidence in parenting may predict parenting behaviors in women who were abused as children, psychologists have found that mothers who experienced more types of maltreatment as children are more critical of their ability to parent successfully. Intervention programs for moms at-risk, therefore, should focus on bolstering mothers’ self-confidence–not just teach parenting skills, the researchers said.... Read more »

  • August 29, 2015
  • 05:17 AM
  • 41 views

Maternal obesity and offspring autism meta-analysed

by Paul Whiteley in Questioning Answers

So: "The meta-analysis results support an increased risk of autism spectrum disorder in children of women who were obese during pregnancy. However, further study is warranted to confirm these results."That was the conclusion reached by Ya-Min Li and colleagues [1] looking at the collected peer-reviewed data currently available on how maternal weight might impact on offspring neurodevelopmental outcomes. Without wishing to blame or stigmatise (this is a blog based on the examination of cold,........ Read more »

  • August 28, 2015
  • 01:59 PM
  • 46 views

Fish oil-diet benefits may be mediated by gut microbes

by Dr. Jekyll in Lunatic Laboratories

Diets rich in fish oil versus diets rich in lard produce very different bacteria in the guts of mice, reports a new study. The researchers transferred these microbes into other mice to see how they affected health. The results suggest that gut bacteria share some of the responsibility for the beneficial effects of fish oil and the harmful effects of lard.... Read more »

  • August 28, 2015
  • 04:05 AM
  • 59 views

Autoantibodies not implicated in cases of autism?

by Paul Whiteley in Questioning Answers

Contrary results are a common feature of the autism peer-reviewed research landscape. No sooner does one group publish the next 'big thing' when it comes to the singular term 'autism' than seemingly opposite results follow suit.So it is with the paper under discussion today by Simran Kalra and colleagues [1] (open-access) who concluded that: "The idea that autoantibodies represent an underlying cause or are biomarkers for autism pathophysiology is not supported by this report."Autoantibodies by ........ Read more »

  • August 27, 2015
  • 01:45 PM
  • 62 views

HIV particles do not cause AIDS, our own immune cells do

by Dr. Jekyll in Lunatic Laboratories

Researchers have revealed that HIV does not cause AIDS by the virus’s direct effect on the host’s immune cells, but rather through the cells’ lethal influence on one another. HIV can either be spread through free-floating virus that directly infect the host immune cells or an infected cell can pass the virus to an uninfected cell.... Read more »

  • August 27, 2015
  • 08:10 AM
  • 66 views

What Does Jimmy Carter Have Against Worms?

by Bill Sullivan in The 'Scope

You may have heard last week that former President Jimmy Carter wants to wipe the guinea worm out. Read why and how he is achieving this goal.... Read more »

  • August 27, 2015
  • 03:58 AM
  • 70 views

Fish oils preventing psychosis: long-term effects?

by Paul Whiteley in Questioning Answers

"This is the first study to show, to the best of our knowledge, that a 12-week intervention with omega-3 PUFAs [polyunsaturated fatty acids] prevented transition to full-threshold psychotic disorder and led to sustained symptomatic and functional improvements in young people with an at-risk mental state for 7 years (median)."So said the quite remarkable findings reported by Paul Amminger and colleagues [1] (open-access available here) who followed up their previous research study [2] l........ Read more »

  • August 26, 2015
  • 01:30 PM
  • 49 views

Fertilization discovery: Do sperm wield tiny harpoons?

by Dr. Jekyll in Lunatic Laboratories

Could the sperm harpoon the egg to facilitate fertilization? That’s the intriguing possibility raised by the University of Virginia School of Medicine’s discovery that a protein within the head of the sperm forms spiky filaments, suggesting that these tiny filaments may lash together the sperm and its target.... Read more »

  • August 26, 2015
  • 03:51 AM
  • 45 views

Atopic dermatitis and autism: systematically reviewed

by Paul Whiteley in Questioning Answers

I briefly want to bring the paper from Lucia Billeci and colleagues [1] to your attention today and the suggestion that following their systematic review of the current peer-reviewed literature, there seemed to be something of "an association between ASD [autism spectrum disorder] and AD [atopic dermatitis]."Atopic, by the way, refers to sensitivity to allergens, and in the case of AD, how such sensitivity manifests on the skin causing itchiness, redness and the skin to ........ Read more »

Billeci L, Tonacci A, Tartarisco G, Ruta L, Pioggia G, & Gangemi S. (2015) Association Between Atopic Dermatitis and Autism Spectrum Disorders: A Systematic Review. American journal of clinical dermatology. PMID: 26254000  

  • August 25, 2015
  • 01:07 PM
  • 73 views

Predicting who will murder his wife or his family

by Dr. Jekyll in Lunatic Laboratories

Murderers who kill intimate partners and family members have a significantly different psychological and forensic profile from murderers who kill people they don’t know, reports a new Northwestern Medicine study that examined the demographics, psychiatric history and neuropsychology of these individuals.... Read more »

  • August 25, 2015
  • 11:24 AM
  • 52 views

Living Kidney Donors Decrease in Qualify of Life Measures 10 years Later

by Cristy at Living Donor 101 in Living Donors Are People Too

This is brand new so I can only get the abstract. A prospective cohort of 100 living kidney donors at the University of Heidelberg were followed for a median of 10 years. [Note: median means mid-point, so half were more than ten and half less than ten]   Clinical data was available for 97 donors …
Continue reading »
The post Living Kidney Donors Decrease in Qualify of Life Measures 10 years Later appeared first on Living Donors Are People Too.
... Read more »

Klop, K., Janki, S., Dooper, P., Weimar, W., Ijzermans, J., & Kok, N. (2015) More than a decade after live donor nephrectomy - a prospective cohort study. Transplant International. DOI: 10.1111/tri.12589  

  • August 25, 2015
  • 03:06 AM
  • 67 views

MOCOS: a new candidate for autism resarch

by Paul Whiteley in Questioning Answers

I'll freely admit that until reading the paper by François Féron and colleagues [1] (open-access available here) I had never heard of MOCOS (MOlybdenum COfactor Sulfurase) before.Described as "an enzyme of the purine metabolism that sulfurates the molybdenum cofactor, thus allowing the two downstream enzymes—xanthine dehydrogenase (XDH) and aldehyde oxidase (AOX1)—to be active", researchers reported that in nasal stem cells provided by a small group of adults diagnosed with an autism ........ Read more »

Féron F, Gepner B, Lacassagne E, Stephan D, Mesnage B, Blanchard MP, Boulanger N, Tardif C, Devèze A, Rousseau S.... (2015) Olfactory stem cells reveal MOCOS as a new player in autism spectrum disorders. Molecular psychiatry. PMID: 26239292  

  • August 24, 2015
  • 04:05 PM
  • 64 views

Argania spinosa has goat ornaments and makes a useful oil

by Rosin Cerate in Rosin Cerate

Argania spinosa (argan) is a tough little tree endemic to a limited area in southwestern Morocco and a bit of very western Algeria (Tindouf). Patchy forests of the tree cover about 800,000 hectares of the semi-arid Sous valley. These represent a unique biotope and have been designated a fancy UNESCO biosphere reserve. The presence of the forests slows desertification, as the drought-resistant trees act to stabilize the soil. Argan trees can live up to 250 years and are able to make do ........ Read more »

Monfalouti HE, Guillaume D, Denhez C, & Charrouf Z. (2010) Therapeutic potential of argan oil: A review. The Journal of Pharmacy and Pharmacology, 62(12), 1669-75. PMID: 21054392  

Paris C, Herin F, Reboux G, Penven E, Barrera C, Guidat C, & Thaon I. (2015) Working with argan cake: A new etiology for hypersensitivity pneumonitis. BMC Pulmonary Medicine, 18. PMID: 25888313  

  • August 24, 2015
  • 01:15 PM
  • 67 views

Genetic overlaps in autoimmune diseases may suggest common therapies

by Dr. Jekyll in Lunatic Laboratories

Scientists who analyzed the genes involved in 10 autoimmune diseases that begin in childhood have discovered 22 genome-wide signals shared by two or more diseases. These shared gene sites may reveal potential new targets for treating many of these diseases, in some cases with existing drugs already available for non-autoimmune disorders.... Read more »

Yun R Li,, Jin Li,, Sihai D Zhao,, Jonathan P Bradfield,, Frank D Mentch,, S Melkorka Maggadottir,, Cuiping Hou,, Debra J Abrams,, Diana Chang,, Feng Gao,.... (2015) Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases. Nature Medicine. DOI: http://.org/10.1038/nm.3933  

  • August 24, 2015
  • 05:54 AM
  • 70 views

Xenotransplants: How a Pig Could Save Your Life

by rebekah morrow in United Academics

While it sounds like something from The Island of Dr. Moreau, physicians and research scientists are convinced that clinical trials will be underway in the near future.... Read more »

Iwase, H., Liu, H., Wijkstrom, M., Zhou, H., Singh, J., Hara, H., Ezzelarab, M., Long, C., Klein, E., Wagner, R.... (2015) Pig kidney graft survival in a baboon for 136 days: longest life-supporting organ graft survival to date. Xenotransplantation, 22(4), 302-309. DOI: 10.1111/xen.12174  

Cooper, D., Ekser, B., & Tector, A. (2015) A brief history of clinical xenotransplantation. International Journal of Surgery. DOI: 10.1016/j.ijsu.2015.06.060  

Cooper DK. (2012) A brief history of cross-species organ transplantation. Proceedings (Baylor University. Medical Center), 25(1), 49-57. PMID: 22275786  

  • August 24, 2015
  • 05:09 AM
  • 70 views

Social Anxiety Disorder and autism (again)

by Paul Whiteley in Questioning Answers

So: "A large subset (50 %) of the adults with ASD [autism spectrum disorder] met diagnostic criteria for SAD [social anxiety disorder]."That was the conclusion reached in the paper by Brenna Maddox & Susan White [1] looking at the overlap between autism and SAD in a small-ish participant group. Social anxiety disorder by the way, refers to 'a persistent and overwhelming fear of social situations'. Alongside a growing body of peer-reviewed research talking about the often ........ Read more »

  • August 23, 2015
  • 03:48 PM
  • 58 views

When zebrafish have scoliosis

by Aurelie in Coffee break Science

“Don’t slouch, sit up straight, or you’ll get scoliosis!” Getting this kind of comment from adults used to infuriate me when I was a teenager, since 1) I did sit up straight, and 2) I already had scoliosis (despite all… Continue reading →... Read more »

Patten SA, Margaritte-Jeannin P, Bernard JC, Alix E, Labalme A, Besson A, Girard SL, Fendri K, Fraisse N, Biot B.... (2015) Functional variants of POC5 identified in patients with idiopathic scoliosis. The Journal of clinical investigation, 125(3), 1124-8. PMID: 25642776  

  • August 23, 2015
  • 01:49 PM
  • 108 views

Want a better relationship and a better sex life?

by Dr. Jekyll in Lunatic Laboratories

If men take up more of the child-care duties, splitting them equally with their female partners, heterosexual couples have more satisfaction with their relationships and their sex lives, according to new research by sociologists. The group used data from more than 900 heterosexual couples’ responses in the 2006 Marital Relationship Study (MARS).... Read more »

Daniel Fowler et al. (2015) Couples That Split Childcare Duties Have Higher Quality Relationships and Sex Lives . American Sociological Association. info:other/Link

  • August 22, 2015
  • 12:49 PM
  • 126 views

Don’t touch that dial: TV’s subliminal influence on women’s perception of pregnancy and birth

by Dr. Jekyll in Lunatic Laboratories

In an era where popular culture is increasingly recognized for its impact on lay understanding of health and medicine, few scholars have looked at television’s powerful role in the creation of patient expectations, especially regarding pregnancy and birth.... Read more »

Danielle Bessett. (2015) As Seen on TV: Women's Views on Television Representations of Pregnancy and Birth. American Sociological Association’s 110th Annual Meeting. info:other/SES-0402165

  • August 22, 2015
  • 05:19 AM
  • 112 views

Maternal folate status and offspring autism risk: where are we up to?

by Paul Whiteley in Questioning Answers

I'd like to briefly draw your attention to the review published by Elizabeth DeVilbiss and colleagues [1] today, covering "what is known about the role of folate in the aetiology of neurodevelopmental disorders."Folate, is a topic that has graced this blog a few times with autism in mind (see here for example) based on various ideas that folate status during pregnancy might have the ability to modify offspring risk of autism [2] alongside the idea that autoimmune processes might act on fola........ Read more »

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