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  • July 9, 2014
  • 01:37 PM
  • 418 views

Lose Weight, Live Longer. Simple, Right?

by Dr. Jekyll in Lunatic Laboratories

Suprise! Really this shouldn’t come as a shock, but adults with extreme obesity have increased risks of dying at a younger age from cancer and other complications like stroke, diabetes, heart disease, […]... Read more »

Kitahara, C., Flint, A., Berrington de Gonzalez, A., Bernstein, L., Brotzman, M., MacInnis, R., Moore, S., Robien, K., Rosenberg, P., Singh, P.... (2014) Association between Class III Obesity (BMI of 40–59 kg/m2) and Mortality: A Pooled Analysis of 20 Prospective Studies. PLoS Medicine, 11(7). DOI: 10.1371/journal.pmed.1001673  

  • July 9, 2014
  • 11:00 AM
  • 348 views

Chimp Talk

by Viputheshwar Sitaraman in Draw Science

Learn how to speak chimp with the newly translated language of chimpanzee gestures in non-play context. [Infographic]... Read more »

Hobaiter C, & Byrne RW. (2014) The Meanings of Chimpanzee Gestures. Current biology : CB. PMID: 24998524  

  • July 9, 2014
  • 01:18 AM
  • 320 views

The Warrior Gene, Back from the Grave

by nooffensebut in The Unsilenced Science

Recently two meta-analyses on the gene, monoamine oxidase A, and its relationship with violence came to opposite conclusions. I review those studies and pose the questions that the scientists were too afraid to answer.... Read more »

  • July 8, 2014
  • 02:17 PM
  • 280 views

Skin Cells and Skin… smells?!

by Dr. Jekyll in Lunatic Laboratories

Yeah we all know that your nose smells. Yawn! Boring I know, this isn’t kindergarten this is Loony Labs! Thankfully that isn’t what I have for you [as much as […]... Read more »

Busse, D., Kudella, P., Grüning, N., Gisselmann, G., Ständer, S., Luger, T., Jacobsen, F., Steinsträßer, L., Paus, R., Gkogkolou, P.... (2014) A Synthetic Sandalwood Odorant Induces Wound Healing Processes in Human Keratinocytes via the Olfactory Receptor OR2AT4. Journal of Investigative Dermatology. DOI: 10.1038/jid.2014.273  

  • July 7, 2014
  • 01:27 PM
  • 322 views

Staying up late? You’re going Crazy

by Dr. Jekyll in Lunatic Laboratories

All night cram sessions, anyone in college has probably had more than just a few of these [okay maybe only if you are a procrastinator like me]. If you have […]... Read more »

  • July 6, 2014
  • 01:10 PM
  • 291 views

New tool helps Doctors treat Menopause

by Dr. Jekyll in Lunatic Laboratories

With the SCOTUS ruling for the Hobby Lobby case [if you have no idea what I am talking about you can read about that anywhere on the net, like here] […]... Read more »

  • July 6, 2014
  • 01:05 PM
  • 387 views

Emperors in danger: penguin populations predicted to decline due to climate change and sea ice loss

by Jonathan Trinastic in Goodnight Earth

New Nature Climate Change research predicts drastic declines in emperor penguin populations by 2100 due to increased variability in sea ice levels.... Read more »

Jenouvrier, S., Holland, M., Stroeve, J., Serreze, M., Barbraud, C., Weimerskirch, H., & Caswell, H. (2014) Projected continent-wide declines of the emperor penguin under climate change. Nature Climate Change. DOI: 10.1038/nclimate2280  

  • July 5, 2014
  • 01:00 PM
  • 262 views

Breast Cancer… and Cholesterol?!

by Dr. Jekyll in Lunatic Laboratories

Cholesterol, it’s bad for the heart. We know LDL bad, HDL good, eat healthier or ruin your arteries. I’m sure most of us have seen the public service announcements [at […]... Read more »

Potluri, R., Lavu, D., Uppal, H., & Chandran, S. (2014) P740 Hyperlipidaemia as a risk factor for breast cancer?. Cardiovascular Research, 103(suppl 1). DOI: 10.1093/cvr/cvu098.160  

  • July 4, 2014
  • 07:50 PM
  • 377 views

Autophagy, Endosomes, and Viral Entry: UVRAG as an interlocutor

by thelonevirologist in Virology Tidbits

Although the role of various autophagy related proteins in viral infections is well established, the role of UVRAG in particular in mediating viral entry has been elusive. A potential role for UVRAG in mediating viral entry can be postulated from the observation that in UVRAG deficient cells cell surface receptor degradation is downregulated. Since UVRAG overexpression is known to target viral proteins to autophagosomes (and thus lead to potential degradation of viral components) and cell surfac........ Read more »

Pryor PR, Mullock BM, Bright NA, Lindsay MR, Gray SR, Richardson SC, Stewart A, James DE, Piper RC, & Luzio JP. (2004) Combinatorial SNARE complexes with VAMP7 or VAMP8 define different late endocytic fusion events. EMBO reports, 5(6), 590-5. PMID: 15133481  

Offenhäuser C, Lei N, Roy S, Collins BM, Stow JL, & Murray RZ. (2011) Syntaxin 11 binds Vti1b and regulates late endosome to lysosome fusion in macrophages. Traffic (Copenhagen, Denmark), 12(6), 762-73. PMID: 21388490  

Liang, C., Lee, J., Inn, K., Gack, M., Li, Q., Roberts, E., Vergne, I., Deretic, V., Feng, P., Akazawa, C.... (2008) Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome maturation and endocytic trafficking. Nature Cell Biology, 10(7), 776-787. DOI: 10.1038/ncb1740  

Lamb CA, Yoshimori T, & Tooze SA. (2013) The autophagosome: origins unknown, biogenesis complex. Nature reviews. Molecular cell biology, 14(12), 759-74. PMID: 24201109  

Ao X, Zou L, & Wu Y. (2014) Regulation of autophagy by the Rab GTPase network. Cell death and differentiation, 21(3), 348-58. PMID: 24440914  

Pirooz SD, He S, Zhang T, Zhang X, Zhao Z, Oh S, O'Connell D, Khalilzadeh P, Amini-Bavil-Olyaee S, Farzan M.... (2014) UVRAG is required for virus entry through combinatorial interaction with the class C-Vps complex and SNAREs. Proceedings of the National Academy of Sciences of the United States of America, 111(7), 2716-21. PMID: 24550300  

Huotari, J., & Helenius, A. (2011) Endosome maturation. The EMBO Journal, 30(17), 3481-3500. DOI: 10.1038/emboj.2011.286  

Berryman, S., Brooks, E., Burman, A., Hawes, P., Roberts, R., Netherton, C., Monaghan, P., Whelband, M., Cottam, E., Elazar, Z.... (2012) Foot-and-Mouth Disease Virus Induces Autophagosomes during Cell Entry via a Class III Phosphatidylinositol 3-Kinase-Independent Pathway. Journal of Virology, 86(23), 12940-12953. DOI: 10.1128/JVI.00846-12  

Alonso C, Galindo I, Cuesta-Geijo MA, Cabezas M, Hernaez B, & Muñoz-Moreno R. (2013) African swine fever virus-cell interactions: from virus entry to cell survival. Virus research, 173(1), 42-57. PMID: 23262167  

Jae LT, Raaben M, Herbert AS, Kuehne AI, Wirchnianski AS, Soh TK, Stubbs SH, Janssen H, Damme M, Saftig P.... (2014) Virus entry. Lassa virus entry requires a trigger-induced receptor switch. Science (New York, N.Y.), 344(6191), 1506-10. PMID: 24970085  

  • July 4, 2014
  • 01:00 PM
  • 465 views

Finally! A Definite Cause of Autism: Hint it isn’t Vaccines

by Dr. Jekyll in Lunatic Laboratories

Autism, not caused by vaccines. In fact I’ve written several posts on the genetic clues to autism, now a new study offers more proof that it is purely genetic [at […]... Read more »

Bernier, R., Golzio, C., Xiong, B., Stessman, H., Coe, B., Penn, O., Witherspoon, K., Gerdts, J., Baker, C., Vulto-van Silfhout, A.... (2014) Disruptive CHD8 Mutations Define a Subtype of Autism Early in Development. Cell. DOI: 10.1016/j.cell.2014.06.017  

  • July 4, 2014
  • 10:48 AM
  • 453 views

Parents’ Income Poorly Predicts SAT Score

by nooffensebut in The Unsilenced Science

Here I publish my original study that disproves family income as an important influence on SAT scores, shows race as having its greatest influence on scores at the highest education and income levels, and provides some preliminary evidence for a hereditary influence.... Read more »

nooffensebut. (2014) Parents’ Income is a Poor Predictor of SAT Score. Open Differential Psychology, 1-19. info:other/

Bartels M, Rietveld MJ, Van Baal GC, & Boomsma DI. (2002) Heritability of educational achievement in 12-year-olds and the overlap with cognitive ability. Twin research : the official journal of the International Society for Twin Studies, 5(6), 544-53. PMID: 12573186  

Duckworth AL, Quinn PD, Lynam DR, Loeber R, & Stouthamer-Loeber M. (2011) Role of test motivation in intelligence testing. Proceedings of the National Academy of Sciences of the United States of America, 108(19), 7716-20. PMID: 21518867  

Duncan, J., Seitz, R.J., Kolodny, J., Bor, D., Herzog, H., Ahmed, A., Newell, F.N., & Emslie, H. (2000) A Neural Basis for General Intelligence. Science, 289(5478), 457-460. DOI: 10.1126/science.289.5478.457  

MacCallum RC, Wegener DT, Uchino BN, & Fabrigar LR. (1993) The problem of equivalent models in applications of covariance structure analysis. Psychological bulletin, 114(1), 185-99. PMID: 8346326  

Marioni RE, Davies G, Hayward C, Liewald D, Kerr SM, Campbell A, Luciano M, Smith BH, Padmanabhan S, Hocking LJ.... (2014) Molecular genetic contributions to socioeconomic status and intelligence. Intelligence, 44(100), 26-32. PMID: 24944428  

Trzaskowski M, Harlaar N, Arden R, Krapohl E, Rimfeld K, McMillan A, Dale PS, & Plomin R. (2014) Genetic influence on family socioeconomic status and children's intelligence. Intelligence, 42(100), 83-88. PMID: 24489417  

  • July 3, 2014
  • 06:20 PM
  • 214 views

Igniting Sparks, Surviving Fireworks and Dog Science July!

by Cobb & Hecht in Do You Believe In Dog?

Hey Julie, well, here I am, back in chilly, wintry Melbourne. #SPARCS2014 was an amazing event - such an intense three days with early feedback suggesting over 40,000 people joined in online for canine science, excitement, wonderful researchers and inspiration!  You've done a great job capturing the essence and feedback of this international conference over at DogSpies on the Scientific American Blog Network. I'm so pleased someone took photos, or I think I would have convinc........ Read more »

  • July 3, 2014
  • 01:00 PM
  • 347 views

Why you Should Not Fear Testosterone Therapy

by Dr. Jekyll in Lunatic Laboratories

Testosterone, to some it’s a bad word, bringing crazy images like “roid rage” and the like. To others with more than just a pop culture understanding it is a lifesaver. […]... Read more »

  • July 3, 2014
  • 02:25 AM
  • 314 views

Journal Club: DNA analysis indicates Bigfoot may be a big fake

by GrrlScientist in Maniraptora

SUMMARY: A new genetic analysis of 'yeti' hair samples reveals they actually originated from dogs, horses, bears or other known mammals. ... Read more »

  • July 2, 2014
  • 03:54 PM
  • 438 views

Plant = Pill?

by Viputheshwar Sitaraman in Draw Science

E. Longfolia: an aphrodisiac, anti-inflammatory, and anti-malarial miracle plant. [Infographic]... Read more »

Tran TV, Malainer C, Schwaiger S, Atanasov AG, Heiss EH, Dirsch VM, & Stuppner H. (2014) NF-κB inhibitors from Eurycoma longifolia. Journal of natural products, 77(3), 483-8. PMID: 24467387  

  • July 2, 2014
  • 01:13 PM
  • 446 views

Saving the Rainforest and the Consequences

by Dr. Jekyll in Lunatic Laboratories

The road to hell is paved with good intentions. This seems even more true when a new study came out that shows, when it comes to fixing deforestation and forest degradation, […]... Read more »

Putz, F., & Romero, C. (2014) Futures of Tropical Forests . Biotropica, 46(4), 495-505. DOI: 10.1111/btp.12124  

  • July 1, 2014
  • 09:37 PM
  • 495 views

DNA analysis indicates Bigfoot may be a big fake | @GrrlScientist

by GrrlScientist in GrrlScientist

A newly-published genetic analysis of hair samples suspected as being from a cryptic primate known by various names such as "bigfoot" or "yeti", has revealed they actually originated from dogs, horses, bears or other well known mammals. ... Read more »

  • July 1, 2014
  • 06:36 PM
  • 43 views

At the source: Finding Bliss in the Brain

by Teodora Stoica in CuriousCortex

Buddhists call it Nirvana. Literally translated to “blowing out,” it refers to the extinction of desire, aversion and delusion. Characterized by blissful egolessness 1, this particular state of mind (or rather, without-mind) has been obscure ever since a certain Siddhārtha Gautama attained it 2,500 years ago. Thankfully, there are people who experience this state effortlessly when misfiring in their brain gives rise to ecstatic seizures. Facilitated by neuroscience we can finally gl........ Read more »

  • July 1, 2014
  • 01:18 PM
  • 326 views

St. Johns Wart and the Dangers of “Alternative” Medicine

by Dr. Jekyll in Lunatic Laboratories

Grapefruit juice, I hate the stuff. But did you know that if you drink as little as 8 oz. of it when you take certain medications it could dramatically increase […]... Read more »

Davis SA, Feldman SR, & Taylor SL. (2014) Use of St. John's Wort in Potentially Dangerous Combinations. Journal of alternative and complementary medicine (New York, N.Y.). PMID: 24956073  

Bailey, D., Malcolm, J., Arnold, O., & David Spence, J. (2002) Grapefruit juice-drug interactions. British Journal of Clinical Pharmacology, 46(2), 101-110. DOI: 10.1046/j.1365-2125.1998.00764.x  

  • July 1, 2014
  • 01:18 PM
  • 268 views

St. Johns Wort and the Dangers of “Alternative” Medicine

by Dr. Jekyll in Lunatic Laboratories

Grapefruit juice, I hate the stuff. But did you know that if you drink as little as 8 oz. of it when you take certain medications it could dramatically increase […]... Read more »

Davis SA, Feldman SR, & Taylor SL. (2014) Use of St. John's Wort in Potentially Dangerous Combinations. Journal of alternative and complementary medicine (New York, N.Y.). PMID: 24956073  

Bailey, D., Malcolm, J., Arnold, O., & David Spence, J. (2002) Grapefruit juice-drug interactions. British Journal of Clinical Pharmacology, 46(2), 101-110. DOI: 10.1046/j.1365-2125.1998.00764.x  

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