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  • April 25, 2015
  • 01:59 PM
  • 19 views

Mental disorders do not predict violence, so please stop

by Dr. Jekyll in Lunatic Laboratories

When Sandy Hook happened, it was so shocking that to this day, some don’t actually believe it happened. Shortly after, something frustrating happened, the shooter was labeled with aspergers. This helped drive the mental health and violence connection to the point that Time came out with an article dispelling that myth. Even now according to new longitudinal study of delinquent youth, most psychiatric disorders – including depression — do not predict future violent behavior. The only except........ Read more »

Elkington, K., Teplin, L., Abram, K., Jakubowski, J., Dulcan, M., & Welty, L. (2015) Psychiatric Disorders and Violence: A Study of Delinquent Youth After Detention. Journal of the American Academy of Child , 54(4), 302-31200000. DOI: 10.1016/j.jaac.2015.01.002  

  • April 24, 2015
  • 04:19 PM
  • 45 views

Diabetes drug found in freshwater potential cause of intersex fish

by Dr. Jekyll in Lunatic Laboratories

A medication commonly taken for Type II diabetes, which is being found in freshwater systems worldwide, has been shown to cause intersex in fish –or male fish that produce eggs. The study determined exposure to the diabetes medicine metformin causes physical changes in male fish exposed to doses similar to the amount in wastewater effluent.... Read more »

  • April 23, 2015
  • 06:25 PM
  • 55 views

Scientists create worlds first genetically modified human embryos

by Dr. Jekyll in Lunatic Laboratories

A funny thing happened on the way to the publisher. In a world first, China has successfully created genetically modified human embryos. It was certainly an amazing piece of science, but the paper was rejected by both Nature and Science. Not because the study was flawed, or because the data was falsified, the paper was rejected for ethical reasons.... Read more »

Liang, P., Xu, Y., Zhang, X., Ding, C., Huang, R., Zhang, Z., Lv, J., Xie, X., Chen, Y., Li, Y.... (2015) CRISPR/Cas9-mediated gene editing in human tripronuclear zygotes. Protein . DOI: 10.1007/s13238-015-0153-5  

  • April 23, 2015
  • 02:53 PM
  • 48 views

Whooping cough: A small drop in vaccine protection can lead to a case upsurge

by Dr. Jekyll in Lunatic Laboratories

In 2012 the USA saw the highest number of pertussis (whooping cough) cases since 1955. New research finds that a likely explanation for this rise in disease is a drop in the degree of vaccine protection for each vaccinated individual. The team worked with 60 years of pertussis disease data to determine what best explained the recent increase in the disease.... Read more »

Gambhir M, Clark TA, Cauchemez S, Tartof SY, Swerdlow DL, & Ferguson NM. (2015) A Change in Vaccine Efficacy and Duration of Protection Explains Recent Rises in Pertussis Incidence in the United States. PLOS Computational Biology. info:/10.1371/journal.pcbi.1004138

  • April 22, 2015
  • 04:27 PM
  • 47 views

Researchers find genetic link between overactive and underactive immune systems

by Dr. Jekyll in Lunatic Laboratories

In the largest genetic study to date of a challenging immunodeficiency disorder, scientists have identified a gene that may be a “missing link” between overactive and underactive immune activity. The gene candidate also plays a key role in autoimmune diseases such as type 1 diabetes, rheumatoid arthritis and even allergies.... Read more »

Li J, Jørgensen SF, Maggadottir SM, Bakay M, Warnatz K, Glessner J, Pandey R, Salzer U, Schmidt RE, Perez E.... (2015) Association of CLEC16A with human common variable immunodeficiency disorder and role in murine B cells. Nature communications, 6804. PMID: 25891430  

  • April 22, 2015
  • 11:42 AM
  • 40 views

Earth Day spotlight: a survey of the aftermath of the Deepwater Horizon oil spill

by Jonathan Trinastic in Goodnight Earth

Five years ago, the Deepwater Horizon oil spill changed the trajectory of ecosystems in the Gulf of Mexico. We take a look at how species have been affected and what we can do to prevent another disaster.... Read more »

Cornwall W. (2015) Deepwater Horizon: after the oil. Science (New York, N.Y.), 348(6230), 22. PMID: 25838362  

  • April 21, 2015
  • 02:01 PM
  • 40 views

Type 1 diabetes: On the way to an insulin vaccine

by Dr. Jekyll in Lunatic Laboratories

Pseudoscience claims about vaccines are seemingly hitting a fever pitch. Despite that, a new vaccine may be on the horizon for children at risk for diabetes, and that is a good thing. Researchers have found that children at risk for type 1 diabetes, who were given daily doses of oral insulin, developed a protective immune response to the disease that could lay the groundwork for a vaccine against the chronic illness.... Read more »

Ezio Bonifacio, PhD, Anette G. Ziegler, MD, Georgeanna Klingensmith, MD, Edith Schober, MD, Polly J. Bingley, MD, Marietta Rottenkolber, Anke Theil, PhD, Anne Eugster, PhD, Ramona Puff, PhD, Claudia Peplow.... (2015) Effects of High-Dose Oral Insulin on Immune Responses in Children at High Risk for Type 1 Diabetes The Pre-POINT Randomized Clinical Trial. Journal of American Medical Association . info:/10.1001/jama.2015.2928

Jay S. Skyler, MD. (2015) Toward Primary Prevention of Type 1 Diabetes. Journal of American Medical Association . info:/10.1001/jama.2015.2054.

  • April 20, 2015
  • 03:36 PM
  • 52 views

Black hole hunters tackle a cosmic conundrum

by Dr. Jekyll in Lunatic Laboratories

While mass media was busy misquoting Stephen Hawking and arguing about black holes, astrophysicists have been hard at work trying to solve still unanswered questions about them. Now a team has not only proven that a supermassive black hole exists in a place where it isn’t supposed to be, but in doing so have opened a new door to what things were like in the early universe.... Read more »

Thomas J. Whalen, Ryan C. Hickox, Amy E. Reines, Jenny E. Greene, Gregory R. Sivakoff, Kelsey E. Johnson, David M. Alexander, & Andy D. Goulding. (2015) Variable Hard X-ray Emission from the Candidate Accreting Black Hole in Dwarf Galaxy Henize 2-10. The Astrophysical journal . arXiv: 1504.03331v1

  • April 19, 2015
  • 01:49 PM
  • 69 views

Botox makes unnerving journey into our nervous system

by Dr. Jekyll in Lunatic Laboratories

New research might bring a frown to even the most heavily botoxed faces, with scientists finding how some of the potent toxin used for cosmetic surgery escapes into the central nervous system. Researchers have shown how Botox – also known as Botulinum neurotoxin serotype A – is transported via our nerves back to the central nervous system.... Read more »

Wang, T., Martin, S., Papadopulos, A., Harper, C., Mavlyutov, T., Niranjan, D., Glass, N., Cooper-White, J., Sibarita, J., Choquet, D.... (2015) Control of Autophagosome Axonal Retrograde Flux by Presynaptic Activity Unveiled Using Botulinum Neurotoxin Type A. Journal of Neuroscience, 35(15), 6179-6194. DOI: 10.1523/JNEUROSCI.3757-14.2015  

  • April 17, 2015
  • 07:47 PM
  • 110 views

Study links brain anatomy, academic achievement, and family income

by Dr. Jekyll in Lunatic Laboratories

Many years of research have shown that for students from lower-income families, standardized test scores and other measures of academic success tend to lag behind those of wealthier students. Well now a new study offers another dimension to this so-called “achievement gap”After imaging the brains of high- and low-income students, they found that the higher-income students had thicker brain cortex in areas associated with visual perception and knowledge accumulation.... Read more »

Allyson Mackey et al. (2015) Students’ Family Income Linked With Brain Anatomy, Academic Achievement. Psychological Science. info:/

  • April 17, 2015
  • 03:56 PM
  • 70 views

Artificial blood vessel lets researchers assess clot removal devices

by Dr. Jekyll in Lunatic Laboratories

For the first time, researchers have created an in vitro, live-cell artificial vessel that can be used to study both the application and effects of devices used to extract life-threatening blood clots in the brain. The artificial vessel could have significant implications for future development of endovascular technologies, including reducing the need for animal models to test new devices or approaches.... Read more »

  • April 17, 2015
  • 03:09 PM
  • 96 views

Peer review: bad with it, worse without it

by SciELO in SciELO in Perspective

Peer review is seen as one of the pillars - if not the most important - of scientific communication. Despite the difficulties in going through the review process, the authors believe that the process improves the quality of the manuscript, and they want to be published on refereed journals that have a sound evaluation mechanism. Recent cases of attempted manipulation of the peer review process by fake reviews concern the international scientific community, however, it does not undermine its cred........ Read more »

Nicholas David, Hamid R. Jamali, Eti Herman, Carol Tenopir, Rachel Volentine, Suzie Allard, & Kenneth Levine. (2015) Peer review: still king in the digital age. Learned Publishing, 28(1), 15-21. DOI: http://dx.doi.org/10.1087/20150104  

  • April 17, 2015
  • 11:15 AM
  • 67 views

The downfall of coal: job trends in a changing energy landscape

by Jonathan Trinastic in Goodnight Earth

Coal jobs have decreased dramatically in the past seven years, but are renewable energy and natural gas jobs compensating? New policy work reveals the geographical patterns in job changes that do not bode well for coal-producing states.... Read more »

  • April 15, 2015
  • 03:45 PM
  • 81 views

Brain development suffers from lack of fish oil fatty acids

by Dr. Jekyll in Lunatic Laboratories

While being inundated with advertisements directed at moms to be, skeptical parents should question the supposed health benefits of anything being sold. However, while recent reports question whether fish oil supplements support heart health, scientists have found that the fatty acids they contain are vitally important to the developing brain. Meaning there might actually be truth in advertising -- this time at least.... Read more »

  • April 15, 2015
  • 08:20 AM
  • 68 views

Eyes on Environment: the organic side of fracking

by Jonathan Trinastic in Goodnight Earth

Little research to date has looked into the organic chemicals from fracking fluid that get into surrounding groundwater - here's how science can help!... Read more »

  • April 14, 2015
  • 03:18 PM
  • 73 views

Watch out Atkins: Over eating fatty foods can alter your muscle metabolism

by Dr. Jekyll in Lunatic Laboratories

More bad news on the obesity front and strangely enough, on the popular diet front too — at least for diets like atkins. New research shows that even short term high-fat diets can change your metabolism. So while you might think that you can get away with eating fatty foods for a few days without it making any significant changes to your body, think again.... Read more »

Anderson, A., Haynie, K., McMillan, R., Osterberg, K., Boutagy, N., Frisard, M., Davy, B., Davy, K., & Hulver, M. (2015) Early skeletal muscle adaptations to short-term high-fat diet in humans before changes in insulin sensitivity. Obesity, 23(4), 720-724. DOI: 10.1002/oby.21031  

  • April 14, 2015
  • 08:45 AM
  • 48 views

Malaria diagnosis with RDT MAbs

by SS in Scientific scrutiny

Examining the business of patenting MAbs against epitopes described before and the need for caution in using MAbs against epitopes reported to be deleted in different parts of the world... Read more »

  • April 13, 2015
  • 03:37 PM
  • 89 views

The placebome: Where genetics and the placebo effect meet

by Dr. Jekyll in Lunatic Laboratories

Placebos have helped to ease symptoms of illness for centuries and have been a fundamental component of clinical research to test new drug therapies for more than 70 years. But why some people respond to placebos and others do not remains under debate.... Read more »

Kathryn T. Hall et al. (2015) Genetics and the placebo effect: the placebome. Trends in Molecular Medicine. info:/10.1016/j.molmed.2015.02.009

  • April 12, 2015
  • 01:36 PM
  • 78 views

Neuronal disorders and energy metabolism

by Dr. Jekyll in Lunatic Laboratories

Scientists in Japan have have discovered how nerve cells adjust to low energy environments during the brain's growth process. Their study may one day help find treatments for nerve cell damage and neurodegenerative disorders such as Alzheimer's and Parkinson's diseases.... Read more »

  • April 11, 2015
  • 01:58 PM
  • 101 views

A glass fiber that brings light to a standstill

by Dr. Jekyll in Lunatic Laboratories

Light is an extremely useful tool for quantum communication, but it has one major disadvantage: it usually travels at the speed of light and cannot be kept in place. A team of scientists at the Vienna University of Technology has now demonstrated that this problem can be solved – not only in strange, unusual quantum systems, but in the glass fiber networks we are already using today.... Read more »

Sayrin, C., Clausen, C., Albrecht, B., Schneeweiss, P., & Rauschenbeutel, A. (2015) Storage of fiber-guided light in a nanofiber-trapped ensemble of cold atoms. Optica, 2(4), 353. DOI: 10.1364/OPTICA.2.000353  

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