I discuss a recent Science review about data regarding the cold tropical Pacific and its relationship to recent global temperature data.... Read more »
Clement, A., & DiNezio, P. (2014) The Tropical Pacific Ocean--Back in the Driver's Seat?. Science, 343(6174), 976-978. DOI: 10.1126/science.1248115
Researchers at the Vienna University of Technology have succeeded for the first time in creating a diode made of tungsten diselenide. Experiments show that this material may be used to create ultrathin flexible solar cells. Even flexible displays could become possible.... Read more »
Pospischil, A., Furchi, M., & Mueller, T. (2014) Solar-energy conversion and light emission in an atomic monolayer p–n diode. Nature Nanotechnology. DOI: 10.1038/nnano.2014.14
Few areas of biomedical research have benefited more from next-gen sequencing than studies of rare inherited diseases. Rapid, inexpensive exome sequencing in individuals with rare, presumably-monogenic diseases has been hugely successful over the past few years. There’s been a lot of discussion in the NGS community about the analysis burden of the large-scale whole-genome sequencing […]... Read more »
Koboldt DC, Larson DE, Sullivan LS, Bowne SJ, Steinberg KM, Churchill JD, Buhr AC, Nutter N, Pierce EA, Blanton SH.... (2014) Exome-Based Mapping and Variant Prioritization for Inherited Mendelian Disorders. American journal of human genetics. PMID: 24560519
This month I will be focusing on sleep and the brain. The importance of sleep to normal and abnormal brain functioning is receiving increased research attention.A variety of sleep abnormalities have been described in major depression and bipolar affective disorder. Depression has been linked to delayed sleep onset, reduced time to first rapid eye movement (REM) period, reduced sleep efficiency and disruption of the circadian rhythm of sleep.Sleep physiology also varies throughout the lifesp........ Read more »
Robillard, R., Naismith, S., Smith, K., Rogers, N., White, D., Terpening, Z., Ip, T., Hermens, D., Whitwell, B., Scott, E.... (2014) Sleep-Wake Cycle in Young and Older Persons with a Lifetime History of Mood Disorders. PLoS ONE, 9(2). DOI: 10.1371/journal.pone.0087763
You might say the benefit of staying alive is an actual no-brainer: even brainless lifeforms do their best not to die. For the most part, anyway. When they’re under stress, single-celled organisms may opt to cut up their DNA and neatly implode. A new study hints that by committing suicide in this way, an organism […]The post Suicidal Algae Help Their Relatives and Harm Their Rivals appeared first on Inkfish.... Read more »
Durand, P., Choudhury, R., Rashidi, A., & Michod, R. (2014) Programmed death in a unicellular organism has species-specific fitness effects. Biology Letters, 10(2), 20131088-20131088. DOI: 10.1098/rsbl.2013.1088
Michele MarksteinUsing a new approach to systematically test chemotherapy drugs in an unusual animal model, a research team led by University of Massachusetts Amherst molecular biologist Michele Markstein, with Norbert Perrimon at Harvard Medical School, report that several have a serious side effect: Inducing hyper proliferation in stem cells that could lead to tumor recurrence.Markstein says, “We discovered that several chemotherapeutics that stop fast growing tumors have the opposite effect........ Read more »
Markstein, M., Dettorre, S., Cho, J., Neumuller, R., Craig-Muller, S., & Perrimon, N. (2014) Systematic screen of chemotherapeutics in Drosophila stem cell tumors. Proceedings of the National Academy of Sciences. DOI: 10.1073/pnas.1401160111
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