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All posts from The Last Seven Days

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  • July 22, 2014
  • 09:08 AM
  • 1 view

A History of Bioinformatics (told from the Year 2039)

by Mary in OpenHelix

A week or so back I was watching the chatter around the #ISMB / #BOSC2014 meeting, and saw a number of amusing and intriguing comments about Titus Brown’s keynote talk. [embedded tweets] You can see a lot of chatter about it in the Storify. I was delighted to soon see this follow up...... Read more »

  • July 22, 2014
  • 07:15 AM
  • 4 views

White or Brown: which is the better fat?

by Shefali Sabharanjak in United Academics

White adipose tissue or white fat has earned notoriety in the current obesity pandemic. But it is not right to throw white fat cells out of the window, just yet. Recent research has shown that conservation of energy-storing white fat cells can help to overcome cachexia brought on by chemotherapy in cancer patients. ... Read more »

Petruzzelli, M., Schweiger, M., Schreiber, R., Campos-Olivas, R., Tsoli, M., Allen, J., Swarbrick, M., Rose-John, S., Rincon, M., Robertson, G.... (2014) A Switch from White to Brown Fat Increases Energy Expenditure in Cancer-Associated Cachexia. Cell Metabolism. DOI: 10.1016/j.cmet.2014.06.011  

  • July 22, 2014
  • 04:32 AM
  • 9 views

Common variation and the genetics of autism

by Paul Whiteley in Questioning Answers

The paper by Trent Gaugler and colleagues [1] reporting that the genetic architecture of the autism spectrum disorders (ASDs) seems in the most part to be due to "common variation" over and above "rare variants or spontaneous glitches" adds to the quite voluminous literature in this area.Everything in proportion? @ Wikipedia Based on an analysis of "a unique epidemiological sample from Sweden" researchers looked at DNA variations in some 3000 individuals with autism and asymptomatic co........ Read more »

Gaugler T, Klei L, Sanders SJ, Bodea CA, Goldberg AP, Lee AB, Mahajan M, Manaa D, Pawitan Y, Reichert J.... (2014) Most genetic risk for autism resides with common variation. Nature genetics. PMID: 25038753  

  • July 21, 2014
  • 02:31 PM
  • 8 views

Do quarks grant confinement?

by Marco Frasca in The Gauge Connection

In 2010 I went to Ghent in Belgium for a very nice Conference on QCD. My contribution was accepted and I had the chance to describe my view about this matter. The result was this contribution to the proceedings. The content of this paper was really revolutionary at that time as my view about Yang-Mills […]... Read more »

Marco Frasca. (2010) Mapping theorem and Green functions in Yang-Mills theory. PoS FacesQCD:039,2010. arXiv: 1011.3643v3

Markus Hopfer, Christian S. Fischer, & Reinhard Alkofer. (2014) Running coupling in the conformal window of large-Nf QCD. arXiv. arXiv: 1405.7031v1

Markus Hopfer, Christian S. Fischer, & Reinhard Alkofer. (2014) Infrared behaviour of propagators and running coupling in the conformal window of QCD. arXiv. arXiv: 1405.7340v1

  • July 21, 2014
  • 05:51 AM
  • 21 views

It's time for Western psychology to recognise that many individuals, and even entire cultures, fear happiness

by Christian Jarrett in BPS Research Digest

It's become a mantra of the modern Western world that the ultimate aim of life is to achieve happiness. Self-help blog posts on how to be happy are almost guaranteed popularity (the Digest has its own!). Pro-happiness organisations have appeared, such as Action for Happiness, which aims to "create a happier society for everyone." Topping it all, an increasing number of governments, including in the UK, have started measuring national well-being (seen as a proxy for "happiness") - the argument be........ Read more »

  • July 21, 2014
  • 03:24 AM
  • 17 views

Autism and asthma yet again

by Paul Whiteley in Questioning Answers

"Asthma is approximately 35 % more common in autistic children".Pipe down @ Wikipedia That was the finding reported by Stanley Kotey and colleagues [1] based on their analysis of the 2007 National Survey of Children's Health (NSCH) dataset, a resource looking at "the physical and emotional health of children ages 0-17 years of age" resident in the United States. I don't intend to dwell too much on the Kotey findings aside from pointing out: (a) the reported prevalence of autism ca........ Read more »

  • July 21, 2014
  • 03:24 AM
  • 18 views

Autism and asthma yet again

by Paul Whiteley in Questioning Answers

"Asthma is approximately 35 % more common in autistic children".Pipe down @ Wikipedia That was the finding reported by Stanley Kotey and colleagues [1] based on their analysis of the 2007 National Survey of Children's Health (NSCH) dataset, a resource looking at "the physical and emotional health of children ages 0-17 years of age" resident in the United States. I don't intend to dwell too much on the Kotey findings aside from pointing out: (a) the reported prevalence of autism ca........ Read more »

  • July 21, 2014
  • 12:05 AM
  • 15 views

It’s Only One Little Muscle Group…The Impact of Lumbar Multifidus Size on Lower Extremity Injury

by Mark A. Sutherlin in Sports Medicine Research (SMR): In the Lab & In the Field

Smaller lumbar multifidus size during preseason and the competitive season was associated with lower extremity injury in Australian Football. Additionally, lumbar multifidus asymmetry, limb kicking dominance and a history of low back pain were also associated with increased lower extremity injury.... Read more »

Hides, J., Stanton, W., Mendis, M., Franettovich Smith, M., & Sexton, M. (2014) Small Multifidus Muscle Size Predicts Football Injuries. Orthopaedic Journal of Sports Medicine, 2(6). DOI: 10.1177/2325967114537588  

  • July 20, 2014
  • 09:13 PM
  • 18 views

Parasite Cures Cancer

by Viputheshwar Sitaraman in Draw Science

A parasite commonly found in the intestines of cats turns out to be an immune system boost against cancer!... Read more »

  • July 20, 2014
  • 05:39 PM
  • 28 views

Bacterial CRISPRs: Not Just For Targeting Foreign Nucleic Acids

by Geoffrey Hannigan in Prophage

In recent years, CRISPRs (Clustered, regularly interspaced, short palindromic repeats) have been gaining popularity in the microbiology field. Briefly, CRISPRs serve as an adaptive immune system for bacteria, meaning that they are able to remember what viruses (bacteriophages) or other entities have infected them and mount a targeted defensive response the next time they are infected with the same entity (think of it as an analog to our adaptive immune response which uses antibodies and other a........ Read more »

Wiedenheft B, Sternberg SH, & Doudna JA. (2012) RNA-guided genetic silencing systems in bacteria and archaea. Nature, 482(7385), 331-8. PMID: 22337052  

Sampson TR, Napier BA, Schroeder MR, Louwen R, Zhao J, Chin CY, Ratner HK, Llewellyn AC, Jones CL, Laroui H.... (2014) A CRISPR-Cas system enhances envelope integrity mediating antibiotic resistance and inflammasome evasion. Proceedings of the National Academy of Sciences of the United States of America. PMID: 25024199  

  • July 20, 2014
  • 03:43 PM
  • 13 views

Babylonian Neurology and Psychiatry

by Neuroskeptic in Neuroskeptic_Discover

A fascinating little paper in Brain examines Neurology and psychiatry in Babylon. It’s a collaboration by British neurologist Edward H. Reynolds and Assyriologist James V. Kinnier Wilson. The sources they discuss are almost 4,000 years old, dating to the Old Babylonian Dynasty of 1894 – 1595 BC. Writing in cuneiform script impressed into clay tablets, […]The post Babylonian Neurology and Psychiatry appeared first on Neuroskeptic.... Read more »

Reynolds EH, & Kinnier Wilson JV. (2014) Neurology and psychiatry in Babylon. Brain : a journal of neurology. PMID: 25037816  

  • July 20, 2014
  • 01:29 PM
  • 34 views

Cooperative sperm, killer sperm and the competition for reproductive success

by Sam Hardman in Ecologica

In the closing paragraph of on the origin of species Darwin famously said that nature was a war in which individuals struggle against each other and the environment for survival. […]... Read more »

Moore H, Dvoráková K, Jenkins N, & Breed W. (2002) Exceptional sperm cooperation in the wood mouse. Nature, 418(6894), 174-7. PMID: 12110888  

Pearcy M, Delescaille N, Lybaert P, & Aron S. (2014) Team swimming in ant spermatozoa. Biology letters, 10(6). PMID: 24919705  

Byrne PG, Simmons LW, & Roberts JD. (2003) Sperm competition and the evolution of gamete morphology in frogs. Proceedings. Biological sciences / The Royal Society, 270(1528), 2079-86. PMID: 14561298  

  • July 20, 2014
  • 11:47 AM
  • 27 views

Neury Thursday: mitochondria, neuron health, and sufficient sleep

by Allison in Dormivigilia

Researchers have uncovered further evidence as to why partial sleep deprivation degrades neuron health at a microscopic level... Read more »

  • July 20, 2014
  • 11:33 AM
  • 30 views

Antiretrovirals and Pregnancy Risk

by Gabriel in Lunatic Laboratories

Don’t drink when you are pregnant, we all know that you aren’t supposed to do that. We also know you shouldn’t smoke, use drugs, and should talk to your Doctor […]... Read more »

Mugo NR, Hong T, Celum C, Donnell D, Bukusi EA, John-Stewart G, Wangisi J, Were E, Heffron R, Matthews LT.... (2014) Pregnancy Incidence and Outcomes Among Women Receiving Preexposure Prophylaxis for HIV Prevention: A Randomized Clinical Trial. JAMA : the journal of the American Medical Association, 312(4), 362-371. PMID: 25038355  

  • July 20, 2014
  • 11:21 AM
  • 15 views

Slowing Heart Disease

by Viputheshwar Sitaraman in Draw Science

Stopping just one minor enzyme leads to an entire cascade of pathways that can slow heart disease.... Read more »

Blazevic T, Schwaiberger AV, Schreiner CE, Schachner D, Schaible AM, Grojer CS, Atanasov AG, Werz O, Dirsch VM, & Heiss EH. (2013) 12/15-lipoxygenase contributes to platelet-derived growth factor-induced activation of signal transducer and activator of transcription 3. The Journal of biological chemistry, 288(49), 35592-603. PMID: 24165129  

  • July 20, 2014
  • 05:19 AM
  • 50 views

Time-lapse video of developing depression and trichotillomania

by Elisabeth Buhl Thubron in United Academics

this young woman took 2100 over 6.5 years. You watch Rebecca as a young 14 year old go through not only the trials and tribulations of adolescent life, but also through the stages of developing major depressive disorder and trichotillomania.... Read more »

  • July 19, 2014
  • 02:39 PM
  • 61 views

HIV and Hepatitis C: A New Treatment Coming Soon!!

by Gabriel in Lunatic Laboratories

The old saying it could always be worse might not sound like it would apply to HIV patients. Then again if you had HIV and hepatitis C, that would probably […]... Read more »

Sulkowski, M., Naggie, S., Lalezari, J., Fessel, W., Mounzer, K., Shuhart, M., Luetkemeyer, A., Asmuth, D., Gaggar, A., Ni, L.... (2014) Sofosbuvir and Ribavirin for Hepatitis C in Patients With HIV Coinfection. JAMA, 312(4), 353. DOI: 10.1001/jama.2014.7734  

  • July 19, 2014
  • 07:10 AM
  • 56 views

CO2 emissions drive heatwaves on despite warming ‘hiatus’

by Andy Extance in Simple Climate

Direct effects from greenhouse gases are playing a significant role in making hot Northern Hemisphere summers more common even as average temperature increases slow down, find Youichi Kamae from the National Institute for Environmental Studies in Japan and his colleagues. ... Read more »

  • July 18, 2014
  • 08:05 PM
  • 56 views

Unraveling the Connections of the Brain

by Gabriel in Lunatic Laboratories

The brain is complex, heck if it wasn’t then we wouldn’t be smart enough to figure out how it works. I guess it’s one of those stupid catch-22 type things. […]... Read more »

  • July 18, 2014
  • 01:55 PM
  • 54 views

July 18, 2014

by Erin Campbell in HighMag Blog

Poor polar bodies typically go the way of that old container of Chinese take-out in your fridge and are eventually dumped. Thanks to a very clever study published in Cell, polar body transfer can prevent the transmission of inherited mitochondrial diseases. Waste not, want not. The meiotic divisions of an oocyte result in the production of an egg in the extrusion of two very small polar bodies. These polar bodies have the same genetic material as the egg but have only a small number of orga........ Read more »

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