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  • March 24, 2011
  • 07:00 AM

March 24, 2011

by Erin Campbell in HighMag Blog

Cancer cells have taught biologists about a lot of wacky things that can happen when things don’t go merrily along for a cell. Entosis is a process in which a living cell is internalized into a neighboring cell, and has been found to occur in some tumors. A recent paper describes exactly what can go wrong here.Aneuploidy refers to a cell having an incorrect number of chromosomes, and is a feature of many cancers. Typically, aneuploidy occurs from a failure in cytokinesis, the physical div........ Read more »

Krajcovic, M., Johnson, N., Sun, Q., Normand, G., Hoover, N., Yao, E., Richardson, A., King, R., Cibas, E., Schnitt, S.... (2011) A non-genetic route to aneuploidy in human cancers. Nature Cell Biology, 13(3), 324-330. DOI: 10.1038/ncb2174  

  • March 24, 2011
  • 03:58 AM

The climate–demography vulnerability index of my mother-in-law

by Jeremy in Agricultural Biodiversity Weblog

Another dispatch from the outer reaches of GISland. Yesterday’s post on the likely consequences of climate change around my mother-in-law’s farm in Kenya got me thinking that it would be nice to see where that locality fits in the global vulnerability scene. One can actually do that thanks to a recent paper in Global Ecology [...]... Read more »

  • March 24, 2011
  • 12:46 AM

Squid Have Mirror Eyeballs!

by Danna Staaf in Squid A Day

It's one of the most persistent problems in camouflage: how do you hide your eyes?
Skin is not that difficult to disguise. You can change its color, cover it up, match it to your environment. But eyes are tricky. You have to be able to see out of them. And unfortunately, predators are extremely good at looking for eyeballs.
I'm not a predator, but I am a marine biologist, which is kind of the same thing. I've done my time searching through plankton soup for squid larvae--and I can tell you the b........ Read more »

  • March 23, 2011
  • 12:41 PM

about my research: gene position and selective constraints

by Giovanni Marco Dall'Olio in BioinfoBlog!

It is time I introduce a bit the research I am doing for my PhD, here at the Pompeu Fabra-CSIC university The main area of our research is to study whether there is correlation between the position of a gene … Continue reading →

Related posts:a discussion about node centralities with G.Scardoni Last week we hosted the visit of G.Scardoni, the author...
scripting Cytoscape to plot different Node Centrality measures Finally I have made it: scripting and automatizing Cytoscape with........... Read more »

  • March 23, 2011
  • 11:45 AM

Blue-light influences what time you wake up:

by Brooke N in Smaller Questions

Very brief review of new Science article showing duel function of CRY protein in Drosophilia circadian rhythms.... Read more »

Im SH, & Taghert PH. (2011) Neuroscience. A CRY to rise. Science (New York, N.Y.), 331(6023), 1394-5. PMID: 21415342  

  • March 23, 2011
  • 10:58 AM

Translational Bioinformatics

by Todd Smith in finchtalk

During the week of March 7, I had the pleasure of attending the AMIA’s (American Medical Informatics Association) summit on Translational Bioinformatics (TBI), at the Parc 55 Hotel in San Francisco.

What is Translational...

[[ This is a content summary only. Visit my website for full links, other content, and more! ]]... Read more »

  • March 23, 2011
  • 09:15 AM

Crushing predators reinvade the Antarctic benthos

by Uncharted Atolls in Uncharted Atolls

In Gotham, Batman drives a batmobile that shoots fire out the back and has all sorts of mechanical wizardry so he can catch fiends in style.  Or something close to that, unless my childhood was dreadfully misinformed.  He isn’t supposed … Continue reading →... Read more »

Aronson RB, Moody RM, Ivany LC, Blake DB, Werner JE, & Glass A. (2009) Climate change and trophic response of the Antarctic bottom fauna. PloS one, 4(2). PMID: 19194490  

GILI, J., ARNTZ, W., PALANQUES, A., OREJAS, C., CLARKE, A., DAYTON, P., ISLA, E., TEIXIDO, N., ROSSI, S., & LOPEZGONZALEZ, P. (2006) A unique assemblage of epibenthic sessile suspension feeders with archaic features in the high-Antarctic. Deep Sea Research Part II: Topical Studies in Oceanography, 53(8-10), 1029-1052. DOI: 10.1016/j.dsr2.2005.10.021  

Clarke, A., Murphy, E., Meredith, M., King, J., Peck, L., Barnes, D., & Smith, R. (2007) Climate change and the marine ecosystem of the western Antarctic Peninsula. Philosophical Transactions of the Royal Society B: Biological Sciences, 362(1477), 149-166. DOI: 10.1098/rstb.2006.1958  

Thatje, S., Anger, K., Calcagno, J., Lovrich, G., Pörtner, H., & Arntz, W. (2005) CHALLENGING THE COLD: CRABS RECONQUER THE ANTARCTIC. Ecology, 86(3), 619-625. DOI: 10.1890/04-0620  

  • March 23, 2011
  • 09:08 AM

Tip of the week: ORegAnno for regulatory annotation

by Mary in OpenHelix

Lately we’re getting a lot of questions about ways to analyze the promoters and other regulatory aspects of genes. And for a while we were mostly pointing to the prediction data that was available in the UCSC Genome Browser’s TFBS Conserved track. TFBS Conserved is a track of computationally predicted transcription factor binding sites (TFBS) which are conserved across human/mouse/rat and based on Transfac v7.0 by BioBase.  As they say in the track description, it’s important........ Read more »

Griffith, O., Montgomery, S., Bernier, B., Chu, B., Kasaian, K., Aerts, S., Mahony, S., Sleumer, M., Bilenky, M., Haeussler, M.... (2007) ORegAnno: an open-access community-driven resource for regulatory annotation. Nucleic Acids Research, 36(Database). DOI: 10.1093/nar/gkm967  

  • March 23, 2011
  • 09:05 AM

In which several evolutionary psychologists still don't understand evolution

by Jeremy Yoder in Denim and Tweed

Jesse Bering has responded to criticism—by me, Jon Wilkins, and P.Z. Meyers, among others—of his post about Gordon Gallup's hypothesis that fear of homosexuals is favored by natural selection, in the form of an interview with Gallup. The result is informative, but probably not in the way intended.

To recap: Gallup proposed that homophobia could be adaptive if it prevented gay and lesbian adults from contacting a homophobic parent's children and—either through actual sexual abuse or some ........ Read more »

  • March 23, 2011
  • 07:43 AM

The many, many mouse-eared bats, aka little brown bats, aka Myotis bats (vesper bats part V)

by Darren Naish in Tetrapod Zoology

One of the largest and most successful vesper bat clades is Myotis, the little brown bats or mouse-eared bats. As you can see from the simplified cladogram shown right down at the bottom of this article, recent work indicates that they form the sister-taxon to the remaining vespertilionine vesper bats (for more discussion of their phylogenetic position, see the vesper bat cladogram article). Myotis occurs virtually worldwide in diverse habitats, contains about 100 species, and has been describ........ Read more »

Ma, J., Jones, G., Zhang, S., Shen, J., Metzner, W., Zhang, L., & Liang, B. (2003) Dietary analysis confirms that Rickett's big-footed bat (Myotis ricketti) is a piscivore. Journal of Zoology, 261(3), 245-248. DOI: 10.1017/S095283690300414X  

  • March 22, 2011
  • 11:48 PM

Cells that vomit fungus and other issues of science papers

by Lorax in Angry by Choice

This weeks journal club was on Cryptococcus neoformans and an odd way it may get of out macrophage some of the time, at least in vitro, maybe. The paper in question is: 

The Human Fungal Pathogen Cryptococcus neoformans Escapes Macrophages by a Phagosome Emptying Mechanism That Is Inhibited by Arp2/3 Complex-Mediated Actin Polymerisation by Simon A. Johnston, Robin C. May. PLoS Pathogens 6(8) e1001041.

This work follows up a really cool observation published by t........ Read more »

  • March 22, 2011
  • 11:46 PM

Better Chemistry Through Breeding

by Matthew DiLeo in The Scientist Gardener

I recently had the opportunity to visit the fabled heart of the USDA-ARS empire: Beltsville.

I heard all about the tornado that knocked down all the campus trees, smashed in the greenhouses and threw doors down hallways a few years ago, visited their food sensory lab (a controlled environment where fruit samples are passed through a wall to waiting taste testers), and saw greenhouses packed full of cacao (where research on one of my favorite fungi, Crinipellis perniciosa, is co-f........ Read more »

Stommel, J.R., & Griesbch, R.J. (2008) Inheritance of Fruit, Foliar, and Plant Habit Attributes in Capsicum. J. Amer. Soc. Hort. Sci., 113(3), 396-407. info:/

Tanaka Y, Brugliera F, Kalc G, Senior M, Dyson B, Nakamura N, Katsumoto Y, & Chandler S. (2010) Flower color modification by engineering of the flavonoid biosynthetic pathway: practical perspectives. Bioscience, biotechnology, and biochemistry, 74(9), 1760-9. PMID: 20834175  

  • March 22, 2011
  • 05:36 PM

Virophage, the virus eater

by Vincent Racaniello in virology blog

A second virophage has been identified. The name does not signify a virus that infects another virus – it means virus eater. The story of virophages begins with the giant mimivirus, originally isolated from a cooling tower in the United Kingdom. It is the largest known virus, with a capsid 750 nanometers in diameter and [...]... Read more »

  • March 22, 2011
  • 02:43 PM

Hello Marine Biologists! What did you do at work today?

by Dr. Carin Bondar in Dr. Carin Bondar - Biologist With a Twist

For those of you that may not be able to guess it from reading my blog – here’s a little factiod: I love, rather LOVE, biology. I’m often daydreaming about various organisms or landscapes – thinking about what it would be like to investigate certain phenomena. It would be nice [...]... Read more »

  • March 22, 2011
  • 01:30 PM

On the origins of smallpox - where and when did variola virus emerge?

by Connor Bamford in The Rule of 6ix

2011 may be the year where the last known officially acknowledged stocks of the deadly smallpox virus, variola are destroyed - a virus that claimed over 500 million lives in the 20th century alone. The extensive collection of 'live' virus and DNA stocks totalling over 500 isolates/strains, which are held between the US Centres for Disease Control and the Russian State Research Centre of Virology and Biotechnology may be ordered to be eliminated following World Health Organisation (WHO) recommend........ Read more »

Li, Y., Carroll, D., Gardner, S., Walsh, M., Vitalis, E., & Damon, I. (2007) From the Cover: On the origin of smallpox: Correlating variola phylogenics with historical smallpox records. Proceedings of the National Academy of Sciences, 104(40), 15787-15792. DOI: 10.1073/pnas.0609268104  

Raymond S. Weinstein. (2011) Should Remaining Stockpiles of Smallpox Virus (Variola) Be Destroyed?. Emerg Infect Dis, 17(Apr). info:/10.3201/eid1704.101865

Rimoin AW, Mulembakani PM, Johnston SC, Lloyd Smith JO, Kisalu NK, Kinkela TL, Blumberg S, Thomassen HA, Pike BL, Fair JN.... (2010) Major increase in human monkeypox incidence 30 years after smallpox vaccination campaigns cease in the Democratic Republic of Congo. Proceedings of the National Academy of Sciences of the United States of America, 107(37), 16262-7. PMID: 20805472  

  • March 22, 2011
  • 12:52 PM

Musical Genes

by Lorna Powell in Elements Science

Lorna Powell tunes into new research that suggests our genes could influence our enjoyment of music.

Related posts:Lung cancer gene means risk for non-smokers too
Whose gene is it anyway?
Smoking can be good for you
... Read more »

  • March 22, 2011
  • 10:55 AM

Cumulative Spatial Sorting: An Overlooked Evolutionary Contributor

by Michael Long in Phased

Geographical edges of species range dispersal are evolutionary focal points.... Read more »

  • March 22, 2011
  • 10:48 AM

Managing landscapes for aesthetics

by Tim De Chant in Per Square Mile

Aesthetics may have more to do with protecting land as a nature reserve than we would like to admit. Wetlands are a perfect example. Few people would consider wetlands to be “beautiful” landscapes—they offer few vistas, are difficult to navigate, and can appear rather homogeneous to the layperson. To many, a swamp is a swamp [...]... Read more »

  • March 22, 2011
  • 10:33 AM

Finding the Family of Acrocanthosaurus

by Brian Switek in Dinosaur Tracking

Allosaurus has one of the dullest names in all of paleontology. The famous dinosaur’s moniker simply means “different reptile”—a bit of a letdown for one of the top predators of Jurassic North America. Early on, the name fit well—Allosaurus was a very unusual dinosaur compared to other large, predatory species—but since 1878 bone hunters have [...]... Read more »

  • March 22, 2011
  • 09:05 AM

Parasitism of a different color

by Jeremy Yoder in Denim and Tweed

The common cuckoo is such a lazy parent that brood parasitism—laying its eggs in the nests of other birds—is built into its biology.

No bird will willingly adopt cuckoo chicks, which usually out-compete, and sometimes kill, their adoptive siblings. Given any hint that one of the eggs in her nest isn't hers, a bird will eject the intruder. So cuckoos have evolved eggs that mimic the coloring of their hosts' eggs—dividing the species into "host races" that specialize on a single host speci........ Read more »

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