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  • October 24, 2016
  • 01:42 PM

Study uncovers brain changes in offending pedophiles

by Dr. Jekyll in Lunatic Laboratories

New research reveals that certain alterations in the brain may be present in pedophiles, with differences between hands-on offenders and those who have not sexually offended against children.

... Read more »

  • October 20, 2016
  • 01:51 PM

Oligodendrocyte selectively myelinates a particular set of axons in the white matter

by Dr. Jekyll in Lunatic Laboratories

There are three kinds of glial cells in the brain, oligodendrocyte, astrocyte and microglia. Oligodendrocytes myelinate neuronal axons to increase conduction velocity of neuronal impulses. A Japanese research team found a characteristic feature of oligodendrocytes that selectively myelinate a particular set of neuronal axons.

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  • October 20, 2016
  • 01:00 PM

Is the reproducibility crisis exacerbated by pre-publication peer review?

by SciELO in SciELO in Perspective

A lack of scrutiny of articles published in peer-reviewed journals on the basis of a belief that pre-publication peer-review provides sufficient scrutiny, may well add to the relatively high number of articles in which results are presented that cannot be replicated. … Read More →... Read more »

  • October 17, 2016
  • 02:01 PM

Cold medicine could stop cancer spread

by Dr. Jekyll in Lunatic Laboratories

Bladder cancer is the seventh most common cancer in males worldwide. Every year, about 20,000 people in Japan are diagnosed with bladder cancer, of whom around 8,000--mostly men--succumb to the disease. Bladder cancers can be grouped into two types: non-muscle-invasive cancers, which have a five-year survival rate of 90 percent, and muscle-invasive cancers, which have poor prognoses.

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  • October 15, 2016
  • 03:26 PM

Untangling a cause of memory loss in neurodegenerative diseases

by Dr. Jekyll in Lunatic Laboratories

Tauopathies are a group of neurodegenerative disorders, including Alzheimer's disease that are characterized by the deposition of aggregates of the tau protein inside brain cells. A new study reveals that the cutting of tau by an enzyme called caspase-2 may play a critical role in the disordered brain circuit function that occurs in these diseases.

... Read more »

Zhao, X., Kotilinek, L., Smith, B., Hlynialuk, C., Zahs, K., Ramsden, M., Cleary, J., & Ashe, K. (2016) Caspase-2 cleavage of tau reversibly impairs memory. Nature Medicine. DOI: 10.1038/nm.4199  

  • October 14, 2016
  • 02:21 PM

Is it possible to normalize citation metrics?

by SciELO in SciELO in Perspective

Bibliometric indicators represent much more than an indication of the visibility, relevance and impact of an article. A researcher’s entire career profile can be summarized in one or more numerical productivity and impact indicators of his research. However, citation metrics vary considerably according to the area of knowledge, the publication age, the type of document and the coverage of the database where citations were accrued. Is it possible to normalize them? Here we discuss the challenges of this practice. … Read More →... Read more »

  • October 13, 2016
  • 01:36 PM

Research improves the practice of environmentally sustainable actions in the medication process in hospitals

by SciELO in SciELO in Perspective

Researchers from the Studies and Research Group in Health Services Administration and Nursing Management from The Universidade Federal de São Paulo (UNIFESP) have developed studies to improve the practice of sustainable actions from an environmental point of view in hospitals. A recent doctoral thesis study carried out by researcher of the UNIFESP and member of the group, analyzed the sustainable actions taken by the nursing staff of an Intensive Care Unit (ICU) during the medication process and proposed interventions to improve environmental sustainability in a large hospital located in São Paulo - Brazil. The article was published in full in the journal Acta Paulista de Enfermagem. … Read More →... Read more »

Patricia de Oliveira Furukawa,, Isabel Cristina Kowal Olm Cunha,, Mavilde da Luz Gonçalves Pedreira,, & Patricia Beryl Marck. (2016) Sustentabilidade ambiental nos processos de medicação realizados na assistência de enfermagem hospitalar. Acta Paulista de Enfermagem, 29(3), 316-324. DOI:  

  • October 12, 2016
  • 01:56 PM

Vitamins A and C help erase cell memory

by Dr. Jekyll in Lunatic Laboratories

Vitamins A and C aren't just good for your health, they affect your DNA too. Researchers have discovered how vitamins A and C act to modify the epigenetic 'memory' held by cells; insight which is significant for regenerative medicine and our ability to reprogramme cells from one identity to another.

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Hore, T., von Meyenn, F., Ravichandran, M., Bachman, M., Ficz, G., Oxley, D., Santos, F., Balasubramanian, S., Jurkowski, T., & Reik, W. (2016) Retinol and ascorbate drive erasure of epigenetic memory and enhance reprogramming to naïve pluripotency by complementary mechanisms. Proceedings of the National Academy of Sciences, 201608679. DOI: 10.1073/pnas.1608679113  

  • October 10, 2016
  • 11:31 AM

Are There Too Few Jobs In Neuroscience?

by Neuroskeptic in Neuroskeptic_Discover

Is European neuroscience facing a jobs crisis? Writing in The Lancet Neurology, Mario Bonato and Esperanza Jubera-Garcia sound the alarm:

As young European neuroscientists, we want to bring attention to the dramatic absence of professional long-term opportunities that researchers are facing mostly, although not exclusively, in the south of Europe.

In the past few years, young scientists from several European countries have been forced to move to other countries, or to quit research a... Read more »

  • October 6, 2016
  • 01:48 PM

Mental illness genetically linked to drug use and misuse

by Dr. Jekyll in Lunatic Laboratories

There are many reports of drug use leading to mental health problems, and we all know of someone having a few too many drinks to cope with a bad day. Many people who are diagnosed with a mental health disorder indulge in drugs, and vice versa. As severity of both increase, problems arise and they become more difficult to treat. But why substance involvement and psychiatric disorders often co-occur is not well understood.

... Read more »

Carey, C., Agrawal, A., Bucholz, K., Hartz, S., Lynskey, M., Nelson, E., Bierut, L., & Bogdan, R. (2016) Associations between Polygenic Risk for Psychiatric Disorders and Substance Involvement. Frontiers in Genetics. DOI: 10.3389/fgene.2016.00149  

  • October 4, 2016
  • 05:36 PM

Revising the meaning of 'prion'

by Dr. Jekyll in Lunatic Laboratories

A team of scientists are redefining what it means to be a prion--a type of protein that can pass heritable traits from cell to cell by its structure instead of by DNA. Although prions are infamous for causing Creutzfeldt-Jakob disease, fatal familial insomnia, and bovine spongiform encephalopathy, commonly known as mad cow's disease, the present study indicates that prions identified in yeast, and possibly in plants, and other organisms may be beneficial.

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Chakrabortee, S., Byers, J., Jones, S., Garcia, D., Bhullar, B., Chang, A., She, R., Lee, L., Fremin, B., Lindquist, S.... (2016) Intrinsically Disordered Proteins Drive Emergence and Inheritance of Biological Traits. Cell. DOI: 10.1016/j.cell.2016.09.017  

  • October 3, 2016
  • 01:54 PM

For women, caffeine could be ally in warding off dementia

by Dr. Jekyll in Lunatic Laboratories

Among a group of older women, self-reported caffeine consumption of more than 261 mg per day was associated with a 36 percent reduction in the risk of incident dementia over 10 years of follow-up. This level is equivalent to two to three 8-oz cups of coffee per day, five to six 8-oz cups of black tea, or seven to eight 12-ounce cans of cola.

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Driscoll, I., Shumaker, S., Snively, B., Margolis, K., Manson, J., Vitolins, M., Rossom, R., & Espeland, M. (2016) Relationships Between Caffeine Intake and Risk for Probable Dementia or Global Cognitive Impairment: The Women’s Health Initiative Memory Study. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences. DOI: 10.1093/gerona/glw078  

  • October 2, 2016
  • 02:32 PM

Sugar gives bees a happy buzz

by Dr. Jekyll in Lunatic Laboratories

An unexpected sugary snack can give bees a little buzz and appears to lift their mood, even making them optimistic, according to research that suggests pollinators have feelings, too. Since emotions are subjective and difficult to measure—particularly in animals—researchers looked at how bees' behavior changed after they were given a sip of sucrose solution.

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  • October 1, 2016
  • 03:20 PM

Nature or nurture: is violence in our genes?

by Dr. Jekyll in Lunatic Laboratories

Nature or nurture? The quest to understand why humans kill one another has occupied the minds of philosophers, sociologists and psychologists for centuries. Are we innately violent, as Englishman Thomas Hobbes postulated in the 1650s, or is our behaviour influenced more by the environment we grow up in, as Jean-Jacques Rousseau theorised a century later?

... Read more »

Gómez, J., Verdú, M., González-Megías, A., & Méndez, M. (2016) The phylogenetic roots of human lethal violence. Nature. DOI: 10.1038/nature19758  

  • September 30, 2016
  • 03:14 PM

Omega-3 fatty acid stops known trigger of lupus

by Dr. Jekyll in Lunatic Laboratories

A team of researchers has found that consuming an omega-3 fatty acid called DHA, or docosahexaenoic acid, can stop a known trigger of lupus and potentially other autoimmune disorders. DHA can be found in fatty, cold-water fish and is produced by the algae that fish eat and store in their bodies. It can be found in fish oil supplements as well, used by more than 30 million Americans.

... Read more »

  • September 29, 2016
  • 11:25 PM

Locating social memories in the brain

by adam phillips in It Ain't Magic

Scientists have identified that social memories are stored in the vetral CA1 region of the brain (in mice). After meeting a mouse and forgetting it, the memories can be reactivated optogenetically, indicating that they exist, but cannot be retrieved after time passes... Read more »

Okuyama, T., Kitamura, T., Roy, D., Itohara, S., & Tonegawa, S. (2016) Ventral CA1 neurons store social memory. Science, 353(6307), 1536-1541. DOI: 10.1126/science.aaf7003  

  • September 29, 2016
  • 01:36 PM

Children could point the way to new HIV treatments

by Dr. Jekyll in Lunatic Laboratories

Children with HIV who can resist the disease progressing could point the way to new treatments for HIV infection that are more widely applicable to infected adults and children alike, an international team of researchers has found.

... Read more »

Muenchhoff, M., Adland, E., Karimanzira, O., Crowther, C., Pace, M., Csala, A., Leitman, E., Moonsamy, A., McGregor, C., Hurst, J.... (2016) Nonprogressing HIV-infected children share fundamental immunological features of nonpathogenic SIV infection. Science Translational Medicine, 8(358), 358-358. DOI: 10.1126/scitranslmed.aag1048  

  • September 28, 2016
  • 01:51 PM

Research team may have observed building blocks of memories in the brain

by Dr. Jekyll in Lunatic Laboratories

A team of researchers has observed what they believe are the building blocks of memories in a mouse brain. In their paper, the researchers describe how they caused certain neurons to become illuminated when they fired, allowing them to watch in real time as memories were made and then later as they were replayed while the mouse was sitting idle.

... Read more »

Malvache, A., Reichinnek, S., Villette, V., Haimerl, C., & Cossart, R. (2016) Awake hippocampal reactivations project onto orthogonal neuronal assemblies. Science, 353(6305), 1280-1283. DOI: 10.1126/science.aaf3319  

  • September 27, 2016
  • 05:50 PM

The unintended consequences of almond milk on California

by Dr. Jekyll in Lunatic Laboratories

A new study using aerial imagery across the state of California has found that converting land to grow almonds between 2007 and 2014 has led to a 27% annual increase in irrigation demands—despite the state's historic drought. The expansion of almonds has also consumed 16,000 acres of wetlands and will likely put additional pressure on already stressed honeybee populations.

... Read more »


  • September 26, 2016
  • 01:35 PM

Why do more men than women commit suicide?

by Dr. Jekyll in Lunatic Laboratories

Why do more men die when they attempt suicide than women? The answer could lie in four traits, finds scientists. There are over 6,000 British lives lost to suicide each year, and nearly 75 per cent of those are male. However, research has found women are more likely to suffer from depression, and to attempt to take their own life.

... Read more »

Deshpande, G., Baxi, M., Witte, T., & Robinson, J. (2016) A Neural Basis for the Acquired Capability for Suicide. Frontiers in Psychiatry. DOI: 10.3389/fpsyt.2016.00125  

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