Post List

  • September 15, 2014
  • 04:47 AM
  • 3 views

Zinc and copper and autism

by Paul Whiteley in Questioning Answers

The paper by Li and colleagues [1] looking at serum copper (Cu) and zinc (Zn) levels in a group of participants diagnosed with an autism spectrum disorder (ASD) is the source material for today's post. Highlighting how "mean serum Zn levels and Zn/Cu ratio were significantly lower in children with ASD compared with normal cases... whereas serum Cu levels were significantly higher" the continued focus on the metallome in autism carries on at a pace. I should at this point out that I'm not in........ Read more »

  • September 15, 2014
  • 12:05 AM
  • 2 views

Acute Gains in Motion After Single Bout of Stretching Predicts Short-Term Gains

by Jane McDevitt in Sports Medicine Research (SMR): In the Lab & In the Field

Acute changes in flexibility after either static or PNF stretching predict the gains in flexibility after a 7-day stretching program.... Read more »

  • September 14, 2014
  • 06:57 PM
  • 22 views

JUST PUBLISHED: The Dance of Communication: Retaining Family Membership Despite Non-Speech Dementia

by Mark Rubin in The University of Newcastle's School of Psychology Newsline

As the majority of people in developed countries will be touched in some way by dementia in the 21st century, current ways of interacting in dementia care may no longer be acceptable. In particular, when people with dementia appear uncommunicative, their retained awareness and ability to interact is often dismissed or overlooked. Facing social isolation and further decline, many languish with unmet needs for human interaction. However, the intimacies of family interaction in dementia care settin........ Read more »

  • September 14, 2014
  • 02:24 PM
  • 24 views

Biospleen Helps Clean Blood to Prevent Sepsis

by Gabriel in Lunatic Laboratories

When a patient has sepsis Things can go downhill fast. A life-threatening condition in which bacteria or fungi multiply in a patient's blood -- sepsis is often too fast for antibiotics to help. But that's all about to change with the introduction of a new device -- inspired by the human spleen -- that may radically transform the way doctors treat sepsis.... Read more »

Kang JH, Super M, Yung CW, Cooper RM, Domansky K, Graveline AR, Mammoto T, Berthet JB, Tobin H, Cartwright MJ.... (2014) An extracorporeal blood-cleansing device for sepsis therapy. Nature medicine. PMID: 25216635  

  • September 14, 2014
  • 10:03 AM
  • 22 views

Sound Aggression

by Rodney Steadman in Gravity's Pull

Maybe it was all the Who noise that made the Grinch so aggressive. Recent research out of Bulgaria suggests a link between noise pollution and displaced aggression.... Read more »

  • September 13, 2014
  • 01:13 PM
  • 45 views

Need a Kidney? Lab Grown Kidneys Coming Soon!

by Gabriel in Lunatic Laboratories

Stem cells offered the promise of having a patents own organ grown to replace a failing or damaged one. Unfortunately the road to that future has been paved with seemingly insurmountable challenges. Thankfully now we are one step closer, researchers have addressed a major challenge in the quest to build replacement kidneys in the lab. Working with human-sized pig kidneys, the scientists developed the most successful method to date to keep blood vessels in the new organs open and flowing with blo........ Read more »

In Kap Ko,, Mehran Abolbashari,, Jennifer Huling,, Cheil Kim,, Sayed-Hadi Mirmalek-Sani,, Mahmoudreza Moradi,, Giuseppe Orlando,, John D. Jackson,, Tamer Aboushwareb,, Shay Soker,.... (2014) Enhanced re-endothelialization of acellular kidney scaffolds for whole organ engineering via antibody conjugation of vasculatures. Technology . info:/10.1142/S2339547814500228

  • September 13, 2014
  • 10:14 AM
  • 45 views

Solving the puzzle of Greenland melting 20,000 years ago

by Jonathan Trinastic in Goodnight Earth

New computer modeling and experimental ice core data shed light on the mystery of Greenland melting 20,000 years ago. This information will be helpful in refining current climate models.... Read more »

Buizert C, Gkinis V, Severinghaus JP, He F, Lecavalier BS, Kindler P, Leuenberger M, Carlson AE, Vinther B, Masson-Delmotte V.... (2014) Greenland temperature response to climate forcing during the last deglaciation. Science (New York, N.Y.), 345(6201), 1177-80. PMID: 25190795  

  • September 12, 2014
  • 09:52 PM
  • 46 views

The Re-emergence of the Minimal Running Shoe

by Craig Payne in Running Research Junkie

The Re-emergence of the Minimal Running Shoe ... Read more »

Davis IS. (2014) The Re-emergence of the Minimal Running Shoe. The Journal of orthopaedic and sports physical therapy, 1-19. PMID: 25211531  

  • September 12, 2014
  • 03:44 PM
  • 52 views

Inflammation of the Brain and Memory Problems

by Gabriel in Lunatic Laboratories

Neurological disorders typically involve memory issues. Most of the problems are attributed to plaques that build up in the brain (which are typically prions), yet some causes are unknown. New research however sheds some light on at least one cause of memory problems. As it turns out brain inflammation can rapidly disrupt our ability to retrieve complex memories of similar but distinct experiences.... Read more »

  • September 12, 2014
  • 11:47 AM
  • 49 views

Insulin, growth hormone and risk of schizophrenia?

by Paul Whiteley in Questioning Answers

"Overall, the present findings suggest that metabolic and hormonal disturbances such as effects on insulin and growth hormone may represent a vulnerability factor to develop mental disorders". That was the conclusion reported by van Beveren and colleagues [1] (open-access) looking at "disruption of insulin and growth factor signaling pathways as an increased risk factor for schizophrenia"."Years ago you served my father in the Clone Wars"Drawing on data derived from participants taking part in&n........ Read more »

  • September 12, 2014
  • 11:18 AM
  • 57 views

Psychologists have compared the mental abilities of Scrabble and crossword champions

by BPS Research Digest in BPS Research Digest

Completed Scrabble (left) and crossword grids (image from Toma et al 2014).Every year, hundreds of word lovers arrive from across the US to compete in the American Crossword Puzzle tournament. They solve clues (e.g. "caught some Z's") and place the answers (e.g. "sleep") in a grid. Meanwhile, a separate group of wordsmiths gather regularly to compete at Scrabble, the game that involves forming words out of letter tiles and finding a suitable place for them on the board.Both sets of players have ........ Read more »

  • September 12, 2014
  • 09:15 AM
  • 49 views

The Friday Five for 09/12/2014

by Bill Sullivan in The 'Scope

Get caught up quick on the hottest science news from this week!... Read more »

Denoeud, F., Carretero-Paulet, L., Dereeper, A., Droc, G., Guyot, R., Pietrella, M., Zheng, C., Alberti, A., Anthony, F., Aprea, G.... (2014) The coffee genome provides insight into the convergent evolution of caffeine biosynthesis. Science, 345(6201), 1181-1184. DOI: 10.1126/science.1255274  

  • September 12, 2014
  • 05:14 AM
  • 65 views

An efficient magnetic field can exist for light particles

by Usman Paracha in SayPeople

Main Points:

Scientists have opened a new window in science by finding that an effective magnetic field can exist for light.
Published in:

Nature Photonics
Study Further:

Magnetic field refers to the line of forces that are present around the permanent magnet or a moving charged particle. This field can change the path of charged particles such as electrons. Usually, magnetic field has no effect on neutral particles such as photons, which are present in light. However, the present stu........ Read more »

Tzuang, L., Fang, K., Nussenzveig, P., Fan, S., & Lipson, M. (2014) Non-reciprocal phase shift induced by an effective magnetic flux for light. Nature Photonics, 8(9), 701-705. DOI: 10.1038/nphoton.2014.177  

  • September 12, 2014
  • 04:38 AM
  • 51 views

Survivorship is an increasingly important component of cancer care

by Lizzie Perdeaux in BHD Research Blog

A cancer survivor is defined as anyone who is living with cancer, or whose cancer has gone into remission. Traditionally cancer care has concentrated on diagnosing and treating the disease, and comparatively little support has been given to patients once … Continue reading →... Read more »

  • September 12, 2014
  • 04:33 AM
  • 53 views

Astrocyte role in gamma waves

by Janet Kwasniak in Neuro-patch

The study of the brain has been very neuron centered. Glial cells outnumber neuron by about 10 to 1 in the cortex and are known to be important to brain function but it is not clear just what they do other than some housekeeping tasks and shepherding neurons to their final locations during development. Astrocyte […]... Read more »

Lee, H., Ghetti, A., Pinto-Duarte, A., Wang, X., Dziewczapolski, G., Galimi, F., Huitron-Resendiz, S., Pina-Crespo, J., Roberts, A., Verma, I.... (2014) Astrocytes contribute to gamma oscillations and recognition memory. Proceedings of the National Academy of Sciences, 111(32). DOI: 10.1073/pnas.1410893111  

  • September 11, 2014
  • 11:00 PM
  • 60 views

Transcendental idealism and Post’s variant of the Church-Turing thesis

by Artem Kaznatcheev in Evolutionary Games Group

One of the exciting things in reading philosophy, its history in particular, is experiencing the tension between different schools of thought. This excitement turns to beauty if a clear synthesis emerges to reconcile the conflicting ideas. In the middle to late 18th century, as the Age of Enlightenment was giving way to the Romantic era, […]... Read more »

Post, E.L. (1936) Finite combinatory processes -- formulation 1. Journal of Symbolic Logic, 1(3), 103-105. info:/

  • September 11, 2014
  • 08:21 PM
  • 55 views

"Barefoot Running and Hip Kinematics: Good News for the Knee?"; what about "Bad News for the Ankle"?

by Craig Payne in Running Research Junkie

"Barefoot Running and Hip Kinematics: Good News for the Knee?"; what about "Bad News for the Ankle"?... Read more »

McCarthy C, Fleming N, Donne B, & Blanksby B. (2014) Barefoot Running and Hip Kinematics: Good News for the Knee?. Medicine and science in sports and exercise. PMID: 25207927  

  • September 11, 2014
  • 03:28 PM
  • 63 views

September 11, 2014

by Erin Campbell in HighMag Blog

As your therapist likely tells you, understanding where you came from is key to accepting where you are now. Take that therapist’s task and multiply it by several million—you now understand the tough job ahead of developmental biologists trying to track cell lineages in complex organisms. Today’s colorful image is from a paper describing a new computational framework for reconstructing cell lineages. The successful tracking of cell position, division, and movement in a developing or........ Read more »

Amat, F., Lemon, W., Mossing, D., McDole, K., Wan, Y., Branson, K., Myers, E., & Keller, P. (2014) Fast, accurate reconstruction of cell lineages from large-scale fluorescence microscopy data. Nature Methods, 11(9), 951-958. DOI: 10.1038/nmeth.3036  

  • September 11, 2014
  • 02:58 PM
  • 65 views

SARS-CoV: formation of the RTC and mitophagy; role of p6 and orf9b

by thelonevirologist in Virology Tidbits

Whilst the nature of the RTC and the role of the CoV non-structural proteins as well the potential role of these proteins in the ER stress response have been discussed in detail before, the role of p6 has been not been discussed. p6 not only induces the formation of membranous vesicles but also recruits nsp-8 to nsp-5, the main viral RNA Polymerase, and induces a ER stress response.
Also the role of SARS-orf9b in the induction of mitophagy is discussed.... Read more »

Otera H, Ishihara N, & Mihara K. (2013) New insights into the function and regulation of mitochondrial fission. Biochimica et biophysica acta, 1833(5), 1256-68. PMID: 23434681  

Kumar P, Gunalan V, Liu B, Chow VT, Druce J, Birch C, Catton M, Fielding BC, Tan YJ, & Lal SK. (2007) The nonstructural protein 8 (nsp8) of the SARS coronavirus interacts with its ORF6 accessory protein. Virology, 366(2), 293-303. PMID: 17532020  

Cruz JL, Sola I, Becares M, Alberca B, Plana J, Enjuanes L, & Zuñiga S. (2011) Coronavirus gene 7 counteracts host defenses and modulates virus virulence. PLoS pathogens, 7(6). PMID: 21695242  

Subissi L, Posthuma CC, Collet A, Zevenhoven-Dobbe JC, Gorbalenya AE, Decroly E, Snijder EJ, Canard B, & Imbert I. (2014) One severe acute respiratory syndrome coronavirus protein complex integrates processive RNA polymerase and exonuclease activities. Proceedings of the National Academy of Sciences of the United States of America. PMID: 25197083  

Moshynskyy I, Viswanathan S, Vasilenko N, Lobanov V, Petric M, Babiuk LA, & Zakhartchouk AN. (2007) Intracellular localization of the SARS coronavirus protein 9b: evidence of active export from the nucleus. Virus research, 127(1), 116-21. PMID: 17448558  

  • September 11, 2014
  • 12:45 PM
  • 75 views

The Origami Brain and a new marker for Schizophrenia

by Gabriel in Lunatic Laboratories

Anyone who has seen pictures or models of the human brain (like the one above) is aware that the outside layer, or cortex, of the brain is folded in an intricate pattern of “hills”, called gyri, and “valleys”, called sulci which give the brain it’s distinctive look. It turns out that the patterns of cortical folding are largely consistent across healthy humans, broadly speaking. However, disturbances in cortical folding patterns suggest deeper disturbances in brain structure and functi........ Read more »

Nanda P, Tandon N, Mathew IT, Giakoumatos CI, Abhishekh HA, Clementz BA, Pearlson GD, Sweeney J, Tamminga CA, & Keshavan MS. (2014) Local gyrification index in probands with psychotic disorders and their first-degree relatives. Biological psychiatry, 76(6), 447-55. PMID: 24369266  

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