Post List

  • July 25, 2014
  • 01:47 PM
  • 1 view

Fighting the Obesity Epidemic with X-box [No, not that one]

by Gabriel in Lunatic Laboratories

Despite all the efforts, people are losing the war on obesity. There is probably a number of factors involved, genetics, underlying medical problems, most of all diet, but in any […]... Read more »

Williams KW, Liu T, Kong X, Fukuda M, Deng Y, Berglund ED, Deng Z, Gao Y, Liu T, Sohn JW.... (2014) Xbp1s in Pomc Neurons Connects ER Stress with Energy Balance and Glucose Homeostasis. Cell metabolism. PMID: 25017942  

  • July 25, 2014
  • 12:00 PM
  • 7 views

The Friday Five 07/25/14

by Bill Sullivan in The 'Scope

Five of the coolest news stories from the past week... Read more »

  • July 25, 2014
  • 11:02 AM
  • 5 views

Risk Factors For Sleep Disturbance After Traumatic Brain Injury

by William Yates, M.D. in Brain Posts

Sleep disturbance following traumatic brain injury (TBI) is a common clinical challenge.Hypersomnia and insomnia can both been seen in the TBI population.The risk factors related to TBI-related sleep disturbance are not well known. Identification of risk factors can provide insight into clinical assessment and management.Lijun Hou and colleagues recently examined risk factors related to subjective sleep complaints in a series of 98 TBI subjects.The study sample include adults admitted to a ........ Read more »

  • July 25, 2014
  • 10:23 AM
  • 7 views

How our judgments about criminals are swayed by disgust, biological explanations and animalistic descriptions

by Christian Jarrett in BPS Research Digest

We expect of our jurors and judges calm, reasoned evaluation of the evidence. Of course we know the reality is rather different - prejudice and emotional reactions will always play their part. Now two new studies add insight into the ways people's legal judgements depart from cool objectivity.Beatrice Capestany and Lasana Harris focused on two main factors - the disgust level of a crime, and whether or not the perpetrators' personality was described in biological terms. Seventeen participants we........ Read more »

  • July 25, 2014
  • 10:07 AM
  • 7 views

BHD causes pneumothoraces during childhood in rare cases

by Lizzie Perdeaux in BHD Research Blog

Birt-Hogg-Dubé Syndrome is caused by inactivating mutations in the FLCN gene, characterised by skin lesions on the face and upper body; lung cysts and predisposition to pneumothorax; and kidney cancer. Although symptoms typically appear in the third and fourth decade … Continue reading →... Read more »

Johannesma PC, van den Borne BE, Gille JJ, Nagelkerke AF, van Waesberghe JT, Paul MA, van Moorselaar RJ, Menko FH, & Postmus PE. (2014) Spontaneous pneumothorax as indicator for Birt-Hogg-Dubé syndrome in paediatric patients. BMC pediatrics, 171. PMID: 24994497  

  • July 25, 2014
  • 09:45 AM
  • 4 views

Some Bees Are Busier Than Others

by Elizabeth Preston in Inkfish

It may be time to leave “busy as a bee” with other dubious animal similes like “happy as a clam” and “drunk as a skunk.” That’s because some bees, it turns out, aren’t all that busy. A small group of hive members do the bulk of the foraging, while their sisters relax at home. But […]The post Some Bees Are Busier Than Others appeared first on Inkfish.... Read more »

  • July 25, 2014
  • 06:44 AM
  • 6 views

Why job interviewers should focus on the candidates, not selling their organisation

by Christian Jarrett in BPS Research Digest

It’s hard to find the best person for the job through an interview. New research uncovers part of the problem: judging a candidate’s calibre becomes trickier when we’re also trying to sell them the benefits of joining the organisation.In an initial study, participants were asked to interview a person (another participant) who was acting as an applicant for a fictional position. Half the interviewers were told their priority was to get a good sense of the applicant, while the rest had to pr........ Read more »

  • July 25, 2014
  • 05:48 AM
  • 5 views

Technique Produces Next-Gen Electrodes for Li-Ion Batteries

by dailyfusion in The Daily Fusion

Scientists at the University of Tokyo have developed an approach with industrial potential to produce nano-sized composite silicon-based powders as negative electrodes for the next generation lithium ion batteries.... Read more »

  • July 25, 2014
  • 03:29 AM
  • 14 views

p-cresol and autism: in need of further research

by Paul Whiteley in Questioning Answers

"These results confirm the elevation of urinary p-cresol in a sizable set of small autistic children and spur interest into biomarker roles for p-cresol and p-cresylsulfate in autism".The peasant dance @ Wikipedia That was the primary conclusion from the paper by Gabriele and colleagues [1] looking at "three components of urinary p-cresol, namely p-cresylsulfate, p-cresylglucuronate and free p-cresol" in samples from 33 participants diagnosed with an autism spectrum disorder (ASD)........ Read more »

Gabriele S, Sacco R, Cerullo S, Neri C, Urbani A, Tripi G, Malvy J, Barthelemy C, Bonnet-Brihault F, & Persico AM. (2014) Urinary p-cresol is elevated in young French children with autism spectrum disorder: a replication study. Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, 1-8. PMID: 25010144  

  • July 24, 2014
  • 08:47 PM
  • 17 views

Know your brain: Meninges

by neurosci in Neuroscientifically Challenged

Where are they?











Close-up view of the meninges surrounding the brain.






The term meninges comes from the Greek for "membrane" and refers to the three membranes that surround the brain and spinal cord. The membrane layers (discussed in detail below) from the outside in are the: dura mater, arachnoid mater, and pia mater. Their positioning around the brain can be seen in the image to the right.What are they and what do they do?The brain is s........ Read more »

Patel, N., & Kirmi, O. (2009) Anatomy and Imaging of the Normal Meninges. Seminars in Ultrasound, CT and MRI, 30(6), 559-564. DOI: 10.1053/j.sult.2009.08.006  

  • July 24, 2014
  • 07:24 PM
  • 21 views

Salmon and Spinal Cod Regeneration, er… Cord

by Gabriel in Lunatic Laboratories

Fish might not be the first thing you think about when we talk spinal cord injury but that is exactly what scientists are doing. Don’t ask where they got the […]... Read more »

  • July 24, 2014
  • 05:30 PM
  • 27 views

Grief in Children and Adolescents

by Eva Alisic in Trauma Recovery

The plane crash in Ukraine brings up many questions related to loss and grief. How will those left behind cope with the devastating event? How can we support them? With regard to how young people cope with bereavement, Dr. Mariken Spuij’s recent articles provide new insights.... Read more »

  • July 24, 2014
  • 04:58 PM
  • 36 views

Why the new paper by Christakis and Fowler on friendship makes me queasy

by neuroecology in Neuroecology

I am a neuroscientist, and as a neuroscientist I have a strange belief that most of who we are comes from our brains. My entire career is based around understanding behavior from this neural level which I feel to be fairly justifiable. So when I see paper looking at the genetics of behavior, I expect to see at […]... Read more »

Christakis NA, & Fowler JH. (2014) Friendship and natural selection. Proceedings of the National Academy of Sciences of the United States of America, 111(Supplement 3), 10796-10801. PMID: 25024208  

Ripke, S., Neale, B., Corvin, A., Walters, J., Farh, K., Holmans, P., Lee, P., Bulik-Sullivan, B., Collier, D., Huang, H.... (2014) Biological insights from 108 schizophrenia-associated genetic loci. Nature, 511(7510), 421-427. DOI: 10.1038/nature13595  

  • July 24, 2014
  • 01:34 PM
  • 35 views

Background TV and Children don’t Mix

by Gabriel in Lunatic Laboratories

Coming from a, to put it gently, very broken home, my babysitter was the television. Yep, so now that you are feeling nice and awkward let’s talk television. New research, […]... Read more »

Linebarger DL, Barr R, Lapierre MA, & Piotrowski JT. (2014) Associations Between Parenting, Media Use, Cumulative Risk, and Children's Executive Functioning. Journal of developmental and behavioral pediatrics : JDBP, 35(6), 367-77. PMID: 25007059  

Lapierre, M., Piotrowski, J., & Linebarger, D. (2012) Background Television in the Homes of US Children. PEDIATRICS, 130(5), 839-846. DOI: 10.1542/peds.2011-2581  

  • July 24, 2014
  • 11:45 AM
  • 37 views

July 24, 2014

by Erin Campbell in HighMag Blog

How many times can you say the word “gonad” in a sentence without giggling? If the answer is one, then I congratulate you on turning thirteen. If the answer is many, then you must be a biologist. Biologists appreciate the value of a good gonad, and so should you. The gonad of the worm C. elegans serves as an important model in which to study tissue organization and development, as you’ll see in the paper that accompanies today’s image. At the end of cell division, cytokinesis typical........ Read more »

Amini, R., Goupil, E., Labella, S., Zetka, M., Maddox, A., Labbe, J., & Chartier, N. (2014) C. elegans Anillin proteins regulate intercellular bridge stability and germline syncytial organization. originally published in the Journal of Cell Biology, 206(1), 129-143. DOI: 10.1083/jcb.201310117  

  • July 24, 2014
  • 04:14 AM
  • 80 views

Prenatal valproate exposure and brains

by Paul Whiteley in Questioning Answers

The paper by Amanda Wood and colleagues [1] (open-access) makes a potentially very important contribution to the growing literature looking at how prenatal exposure to sodium valproate (VPA) may affect some children. Authors reported on: "regional structural cortical brain changes in humans exposed to VPA in utero" and specifically, increased cortical thickness in the left inferior frontal gyrus.Lightning and lava @ Oliver Spalt @ Wikipedia In case you need any background on the s........ Read more »

Wood, A., Chen, J., Barton, S., Nadebaum, C., Anderson, V., Catroppa, C., Reutens, D., O'Brien, T., & Vajda, F. (2014) Altered cortical thickness following prenatal sodium valproate exposure. Annals of Clinical and Translational Neurology. DOI: 10.1002/acn3.74  

  • July 24, 2014
  • 02:55 AM
  • 30 views

Quick, Somebody Get The Name Of That Shark!

by Mark E. Lasbury in The 'Scope

There has been a rash of great white shark sightings and attacks in the news recently. But, have attacks and sightings remained constant, or are they really on the increase? Several news studies provide evidence that the Marine Mammal Protection Act of 1972, the ban on commercial whaling in 1982, and the ban on great white hunting in 1997 have increased the number of sharks on the coasts of the North America and Australia. In addition, great white sharks live much longer than previously assumed,........ Read more »

  • July 23, 2014
  • 05:51 PM
  • 95 views

Lanthanum-Based Perovskite Materials to Improve Fuel Cells

by dailyfusion in The Daily Fusion

Scientists at the University of the Basque Country (UPV/EHU) have studied the effects of using lanthanum-based perovskite ceramic contact materials in solid oxide fuel cells (SOFCs).... Read more »

  • July 23, 2014
  • 05:05 PM
  • 99 views

Japanese Encephalitis Virus (JEV), ER stress, and Apoptosis

by thelonevirologist in Virology Tidbits

Japanese Encephalitis Virus (JEV) is a causative agent of acute encephalitis in humans, and being an arthropod borne virus transmitted predominately by mosquitoes ( that primarily target domestic animals and humans, with an estimated mortality of up to 70000 deaths reported per annum. Upon infection the viral proteins localise to the ER where they induce the ER stress which eventually induces Caspase dependent apoptosis.
... Read more »

Unni SK, Růžek D, Chhatbar C, Mishra R, Johri MK, & Singh SK. (2011) Japanese encephalitis virus: from genome to infectome. Microbes and infection / Institut Pasteur, 13(4), 312-21. PMID: 21238600  

Cui J, Counor D, Shen D, Sun G, He H, Deubel V, & Zhang S. (2008) Detection of Japanese encephalitis virus antibodies in bats in Southern China. The American journal of tropical medicine and hygiene, 78(6), 1007-11. PMID: 18541785  

Mori Y, Okabayashi T, Yamashita T, Zhao Z, Wakita T, Yasui K, Hasebe F, Tadano M, Konishi E, Moriishi K.... (2005) Nuclear localization of Japanese encephalitis virus core protein enhances viral replication. Journal of virology, 79(6), 3448-58. PMID: 15731239  

Uchil PD, Kumar AV, & Satchidanandam V. (2006) Nuclear localization of flavivirus RNA synthesis in infected cells. Journal of virology, 80(11), 5451-64. PMID: 16699025  

Ghosh Roy S, Sadigh B, Datan E, Lockshin RA, & Zakeri Z. (2014) Regulation of cell survival and death during Flavivirus infections. World journal of biological chemistry, 5(2), 93-105. PMID: 24921001  

Lu, M., Lawrence, D., Marsters, S., Acosta-Alvear, D., Kimmig, P., Mendez, A., Paton, A., Paton, J., Walter, P., & Ashkenazi, A. (2014) Opposing unfolded-protein-response signals converge on death receptor 5 to control apoptosis. Science, 345(6192), 98-101. DOI: 10.1126/science.1254312  

Han J, Back SH, Hur J, Lin YH, Gildersleeve R, Shan J, Yuan CL, Krokowski D, Wang S, Hatzoglou M.... (2013) ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death. Nature cell biology, 15(5), 481-90. PMID: 23624402  

  • July 23, 2014
  • 03:43 PM
  • 93 views

Physicians face difficult choices when treating patients with bipolar and obsessive compulsive disorders

by Valerie Ashton in The Molecular Scribe

New research suggests patients with both bipolar disorder and obsessive compulsive disorder should receive treatments for bipolar disorder alone. Bipolar and obsessive compulsive disorder therapies taken together can cause worsening of disease symptoms, making it difficult for physicians to treat both conditions. This is a concern as over 1 in 5 patients with bipolar disorder develop obsessive compulsive disorder during their lifetime.... Read more »

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