Everyone knows that exercise improves health, and ongoing research continues to uncover increasingly detailed information on its benefits for metabolism, circulation, and improved functioning of organs such as the heart, brain, and liver. With this knowledge in hand, scientists may be better equipped to develop “exercise pills” that could mimic at least some of the beneficial effects of physical exercise on the body. But a review of current development efforts ponders whether such pills will........ Read more »
Laher, & et al. (2015) Exercise Pills: At the Starting Line?. Trends in Pharmacological Sciences. info:/http://dx.doi.org/10.1016/j.tips.2015.08.014
"Children born after an IPI [interpregnancy interval] of <12 months or ≥72 months had a 2- to 3-fold increased ASD [autism spectrum disorder] risk compared with children born after an interval of 36 to 47 months."So said the study results published by Ousseny Zerbo and colleagues  looking at the increasingly interesting area of the autism research landscape: the interpregnancy interval (the time from the birth of an index child to the next conception/pregnancy of........ Read more »
Zerbo, O., Yoshida, C., Gunderson, E., Dorward, K., & Croen, L. (2015) Interpregnancy Interval and Risk of Autism Spectrum Disorders. PEDIATRICS. DOI: 10.1542/peds.2015-1099
Well bad news for those of us who have a sweet tooth, a diet high in processed fructose sabotages rat brains’ ability to heal after head trauma, UCLA neuroscientists report. While this doesn’t necessarily translate to humans quite yet, it should still raise a few eyebrows given the results from the study.... Read more »
Rahul Agrawal, Emily Noble1, Laurent Vergnes, Zhe Ying1, Karen Reue, & Fernando Gomez-Pinilla. (2015) Dietary fructose aggravates the pathobiology of traumatic brain injury by influencing energy homeostasis and plasticity. Journal of Cerebral Blood Flow . info:/10.1177/0271678X15606719
Who doesn't enjoy waking to a pleasant smell wafting past? Unfortunately for them, the penguins in a recent study woke up not to pancakes frying nearby, but to less appetizing aromas—for example, feces on a stick. But scientists promise the experiment taught them valuable lessons about a penguin's capabilities. Besides, they let the birds go right back to sleep.
"Research into the sense of smell in birds has a bit of a dubious history," says Gregory Cunningham, a biologist at St. John F........ Read more »
Cunningham GB, & Bonadonna F. (2015) King penguins can detect two odours associated with conspecifics. The Journal of experimental biology. PMID: 26385329
Galileo Bust in Galileo Museum, Florence (wryates photo)There is a significant level of interest in the best behavioral activity balance in adolescents.Adolescents currently live in an environment of expanding opportunities for spending time watching TV, surfing the internet and playing video games.Understanding the best balance of study, exercise and time in front of a screen is an important topic.Kristen Corder and colleagues recently examined adolescent behavioral activity patterns and perfor........ Read more »
Corder K, Atkin AJ, Bamber DJ, Brage S, Dunn VJ, Ekelund U, Owens M, van Sluijs EM, & Goodyer IM. (2015) Revising on the run or studying on the sofa: prospective associations between physical activity, sedentary behaviour, and exam results in British adolescents. The international journal of behavioral nutrition and physical activity, 12(1), 106. PMID: 26337325
My efforts turn once again to Taiwan today and the results reported by Yu-Chiau Shyu and colleagues  that: "Compared to the control group, the ADHD [attention-deficit hyperactivity disorder] group showed significantly increased risk of developing any psychotic disorder... and schizophrenia."As per the multitude of other instances where Taiwan is mentioned as a research powerhouse, the source data for the Shyu findings was the Taiwan National Health Insurance Research Database&n........ Read more »
Shyu YC, Yuan SS, Lee SY, Yang CJ, Yang KC, Lee TL, & Wang LJ. (2015) Attention-deficit/hyperactivity disorder, methylphenidate use and the risk of developing schizophrenia spectrum disorders: A nationwide population-based study in Taiwan. Schizophrenia research. PMID: 26363968
In pop culture, conspiracy believers — like FBI agent Fox Mulder on The X Files or professor Robert Langdon in The Da Vinci Code — tend to reject the notion of coincidence or chance; even the most random-seeming events are thought to result from some sort of intention or design. And researchers have suggested that such a bias against randomness may explain real-world conspiracy beliefs. But new research from psychological scientists shows no evidence for a link between conspiracist thinking ........ Read more »
Dieguez, S., Wagner-Egger, P., & Gauvrit, N. (2015) Nothing Happens by Accident, or Does It? A Low Prior for Randomness Does Not Explain Belief in Conspiracy Theories. Psychological Science. DOI: 10.1177/0956797615598740
MedicalResearch.com Interview with: Ann-Cathrine Larsen MD, PhD-student University of Copenhagen Faculty of Health Sciences Department of Neuroscience and Pharmacology, Eye Pathology Section Copenhagen Medical Research: What is the background for this study? Dr. Larsen: Conjunctival melanoma is an uncommon malignancy … Continue reading →
The post Factors Associated With Aggressive Conjunctival Melanoma Outlined appeared first on MedicalResearch.com.
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Ann-Cathrine Larsen. (2015) Factors Associated With Aggressive Conjunctival Melanoma Outlined. MedicalResearch.com. info:/
MedicalResearch.com Interview with: Michael P. Sherman, MD, FAAP Professor, Department of Child Health University of Missouri – Columbia Women’s and Children’s Hospital Columbia, Missouri 65201 Medical Research: What is the background for this study? Dr. Sherman: We understand eosinophils are … Continue reading →
The post Allergy Cells Predict Bowel Complications In Preterm Babies appeared first on MedicalResearch.com.
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Michael P. Sherman, MD, FAAP. (2015) Allergy Cells Predict Bowel Complications In Preterm Babies. MedicalResearch.com. info:/
Sharing of research data (open data) is increasing in all areas related to scientific research, and it involves authors, journals, publishers, funding agencies, the productive sector and society. In order to encourage authors to provide and reuse datasets, it is paramount to find ways to measure their impact. The initiative ‘Making Data Count’ is efficiently doing this, find out how. … Read More →... Read more »
MedicalResearch.com Interview with: Tanja D de Gruijl PhD Professor Translational Tumor Immunology Head Immunotherapy Lab Department of Medical Oncology VU University medical center-Cancer Center Amsterdam Amsterdam, The Netherlands Medical Research: What is the background for this study? What are the main … Continue reading →
The post Vaccinating New Melanoma Patients With Immune Booster Reduced Tumor Recurrences appeared first on MedicalResearch.com.
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Tanja D de Gruijl PhD. (2015) Vaccinating New Melanoma Patients With Immune Booster Reduced Tumor Recurrences. MedicalResearch.com. info:/
Jessica Alba's company has been charged with two lawsuits citing ineffective protection by her Honest Company sunscreen. The failure of the sunscreen highlights a need for better education regarding sunscreen use and sun exposure.... Read more »
MedicalResearch.com Interview with: Dr Jonas Minet Kinge PhD Researcher, Department of Health Statistics, Norwegian Institute of Public Health Associate professor, Department of Health Management and Health Economics University of Oslo Norwegian Institute of Public Health Oslo, Norway Medical Research: What is the … Continue reading →
The post In Rich Countries, It’s the Poor Who Become Obese appeared first on MedicalResearch.com.
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Dr Jonas Minet Kinge PhD. (2015) In Rich Countries, It's the Poor Who Become Obese. MedicalResearch.com. info:/
MedicalResearch.com Interview with: Dr. Germaine Louis Buck PhD Senior Investigator and Director of the Division of Epidemiology, Statistics and Prevention Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) National Institutes of Health Medical Research: What is the … Continue reading →
The post Fetal Weight Found To Vary By Race and Ethnicity appeared first on MedicalResearch.com.
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Dr. Louis Germaine Buck PhD. (2015) Fetal Weight Found To Vary By Race and Ethnicity. MedicalResearch.com. info:/
Metagenomic profiling, also called metagenomic shotgun sequencing (MSS) represents a powerful application made possible by the digital nature of next-gen sequencing technologies. In it, one basically sequences a sample isolate obtained from somewhere — a shovelful of dirt, a scoop of plankton, or anything else that contains living organisms. MSS has proven particularly useful to […]... Read more »
Wylie TN, Wylie KM, Herter BN, & Storch GA. (2015) Enhanced virome sequencing through solution-based capture enrichment. Genome research. PMID: 26395152
Three big ideas from World Water Week 2015
World Water Week is an annual conference organised by the Stockholm International Water Institute that discusses global issues concerning water. Held in August 2015, World Water Week attracted over 3,000 participants, including government ministers, scientists and economists, from 130 different countries. To celebrate its 25th anniversary this year, here are 3 big ideas from World Water Week 2015.... Read more »
Today I'm serving up the paper by Milo Careaga and colleagues  for your blogging delight, who concluded that: "Children with ASD [autism spectrum disorder] may be phenotypically characterized based upon their immune profile." Further that there may be: "several possible immune subphenotypes within the ASD population that correlate with more severe behavioral impairments."With many thanks to Natasa for the paper, participants - 50 boys with a median age of 3.2 years diagnosed wi........ Read more »
Milo Careaga, Sally Rogers, Robin L. Hansen, David G. Amaral, Judy Van de Water, & Paul Ashwood. (2015) Immune endophenotypes in children with autism spectrum disorder. Biological Psychiatry. info:/10.1016/j.biopsych.2015.08.036
The AVE–SV comparison (Fornell & Larcker, 1981) is certainly the most common technique for detecting discriminant validity violations on the construct level. An alternative technique, proposed by Henseler et al. (2015), is the heterotrait–monotrait (HTMT) ratio of correlations (see the video below). Based on simulation data, these authors show for variance-based structural equation modeling (SEM), […]... Read more »
Fornell, C., & Larcker, D. (1981) Evaluating Structural Equation Models with Unobservable Variables and Measurement Error. Journal of Marketing Research, 18(1), 39. DOI: 10.2307/3151312
Henseler, J., Ringle, C., & Sarstedt, M. (2014) A New Criterion for Assessing Discriminant Validity in Variance-based Structural Equation Modeling. Journal of the Academy of Marketing Science, 43(1), 115-135. DOI: 10.1007/s11747-014-0403-8
Voorhees, C., Brady, M., Calantone, R., & Ramirez, E. (2015) Discriminant Validity Testing in Marketing: An Analysis, Causes for Concern, and Proposed Remedies. Journal of the Academy of Marketing Science. DOI: 10.1007/s11747-015-0455-4
Scientists from the Florida campus of The Scripps Research Institute (TSRI) have uncovered a significant–and potentially treatable–relationship between a chemical that helps transmit signals in the brain and genetic mutations present in a subset of individuals with autism spectrum disorder. The new research findings focus on the role that the neurotransmitter serotonin plays in the development of social behavior.... Read more »
Séjourné, J., Llaneza, D., Kuti, O., & Page, D. (2015) Social Behavioral Deficits Coincide with the Onset of Seizure Susceptibility in Mice Lacking Serotonin Receptor 2c. PLOS ONE, 10(8). DOI: 10.1371/journal.pone.0136494
It’s pretty well established now that there is a statistical connection between intelligence and non-belief. The effect is small, but it’s consistent and has been shown many times. Education, however, is a different matter. Some studies show that educated people are more religious, while others find they are less religious. Now there’s an obvious problem [Read More...]... Read more »
Ganzach, Y., & Gotlibovski, C. (2014) Individual differences and the effect of education on religiosity. Learning and Individual Differences, 213-217. DOI: 10.1016/j.lindif.2014.10.007
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