Post List

  • September 1, 2014
  • 03:12 PM
  • 7 views

The hope behind climate change: adaptation strategies for coastal regions

by Jonathan Trinastic in Goodnight Earth

Hopeful news on Labor Day! A commentary discusses how IPCC reports have become more optimistic and describes adaptation pathways being used by coastal regions to prepare for climate change.... Read more »

Brown, S., Nicholls, R., Hanson, S., Brundrit, G., Dearing, J., Dickson, M., Gallop, S., Gao, S., Haigh, I., Hinkel, J.... (2014) Shifting perspectives on coastal impacts and adaptation. Nature Climate Change, 4(9), 752-755. DOI: 10.1038/nclimate2344  

  • September 1, 2014
  • 02:12 PM
  • 7 views

Assemblages: 50 Years Later, We Know Nothing About Them

by Gabriel in Lunatic Laboratories

You would think we learn about every part of a cell in biology, but we really don't. Case in point, about 50 years ago, electron microscopy revealed the presence of tiny blob-like structures that form inside cells, move around and disappear. The reason you probably haven't heard of these structures is because scientists really don't know what they do even 50 years later. Although they do have an idea about them, these shifting cloud-like collections of proteins are believed to be crucial to the ........ Read more »

  • September 1, 2014
  • 11:57 AM
  • 7 views

Students with more autistic traits make fewer altruistic choices

by BPS Research Digest in BPS Research Digest

Most people with autism have difficulties socialising and connecting with others. It's generally agreed that part of this has to do with an impairment in taking other people's perspective. More specifically, an emerging consensus suggests that autism is associated with having normal feelings for other people, but an impaired understanding of them. Little explored before now is how this affects the behaviour of people with autism towards others who need help.Leila Jameel and her colleagues survey........ Read more »

Jameel L, Vyas K, Bellesi G, Roberts V, & Channon S. (2014) Going 'Above and Beyond': Are Those High in Autistic Traits Less Pro-social?. Journal of autism and developmental disorders, 44(8), 1846-58. PMID: 24522968  

  • September 1, 2014
  • 08:28 AM
  • 8 views

Tracking the Daily Microbiome

by Stephanie Swift in mmmbitesizescience

Humans are essentially 90% bacteria. These bacteria pepper our skin and hang out in our digestive tracts, helping to break down complex carbohydrates and keeping bad bugs in check. We know how the human microbiome (our collection of bacteria) gets … Continue reading →... Read more »

David LA, Materna AC, Friedman J, Campos-Baptista MI, Blackburn MC, Perrotta A, Erdman SE, & Alm EJ. (2014) Host lifestyle affects human microbiota on daily timescales. Genome biology, 15(7). PMID: 25146375  

  • September 1, 2014
  • 07:56 AM
  • 13 views

New Clues Revealed about the Longevity of Naked Mole Rats

by beredim in Strange Animals

Naked Mole RatCredit: UT Health Science Center at San AntonioThe hairless, odd-looking creature in the photo is a naked mole rat (Heterocephalus glaber).Among many weird traits, the species also holds the record for longest living rodent. For comparison, the house mouse (Mus musculus) has a maximum lifespan of just 2-3 years, whereas naked mole rats have been recorded to live as much as 32 years!The exact mechanisms behind the species remarkable longevity have yet to be clearly unveiled, ho........ Read more »

  • September 1, 2014
  • 03:32 AM
  • 19 views

Lithium for mood disorder symptoms in autism?

by Paul Whiteley in Questioning Answers

Modern classroom? @ Wikipedia The paper published by Matthew Siegel and colleagues [1] talking about some preliminary observations on the use of lithium where symptoms of mood disorder might be present in cases of autism spectrum disorder (ASD) caught my eye recently. Concluding that: "lithium may be a medication of interest for those who exhibit two or more mood disorder symptoms, particularly mania or euphoria/elevated mood" the sentiments of more research-to-do in this area presents........ Read more »

Siegel M, Beresford CA, Bunker M, Verdi M, Vishnevetsky D, Karlsson C, Teer O, Stedman A, & Smith KA. (2014) Preliminary Investigation of Lithium for Mood Disorder Symptoms in Children and Adolescents with Autism Spectrum Disorder. Journal of child and adolescent psychopharmacology. PMID: 25093602  

  • August 31, 2014
  • 11:31 PM
  • 20 views

August lives up to its definition: respected and impressive

by Cobb & Hecht in Do You Believe In Dog?

The things we noticed in and around canine science over the past two weeks, Storified in one neat location for your convenience:[View the story "Do You Believe in Dog? [16-31 August 2014]" on Storify] Further reading:Feuerbacher E.N. (2014). Shut up and pet me! Domestic dogs (Canis lupus familiaris) prefer petting to vocal praise in concurrent and single-alternative choice procedures, Behavioural Processes, DOI: http://dx.doi.org/10.1016/j.beproc.2014.08.019 Gygax L. (2014). The A to Z of sta........ Read more »

  • August 31, 2014
  • 06:36 PM
  • 37 views

Whitman Was Not a Neuroscientist

by The Neurocritic in The Neurocritic

Do I contradict myself?Very well then I contradict myself,(I am large, I contain multitudes.)-Walt Whitman, "Song of Myself" (from Leaves of Grass)Science is the search for objective truth based on physical laws of the universe. Scientific theories try to explain the consistent and predictable behavior of natural systems. They are generally reductionist, meaning that complex systems are reduced to simpler and more fundamental elements. The principles of physics, for instance, are expressed in th........ Read more »

  • August 31, 2014
  • 06:28 PM
  • 27 views

Chikungunya Virus and NDP52: a deadly association?

by thelonevirologist in Virology Tidbits

Chikungunya virus (CHIKV) is the causative agent of an arthropod (mosquito) transmitted disease which is characterised by a high fever, rash, joint pain, and arthritis which was reported in 1952 in Tanzania but has spread since to Europe, the Americas, Asia, and Australia and currently epidemic in the Americas. In this post, the importance of p62/SQSTM1 and NDP52 is discussed in the light of apoptosis induction and viral assembly.... Read more »

Kujala P, Ikäheimonen A, Ehsani N, Vihinen H, Auvinen P, & Kääriäinen L. (2001) Biogenesis of the Semliki Forest virus RNA replication complex. Journal of virology, 75(8), 3873-84. PMID: 11264376  

Krejbich-Trotot P, Gay B, Li-Pat-Yuen G, Hoarau JJ, Jaffar-Bandjee MC, Briant L, Gasque P, & Denizot M. (2011) Chikungunya triggers an autophagic process which promotes viral replication. Virology journal, 432. PMID: 21902836  

Mostowy S, Sancho-Shimizu V, Hamon MA, Simeone R, Brosch R, Johansen T, & Cossart P. (2011) p62 and NDP52 proteins target intracytosolic Shigella and Listeria to different autophagy pathways. The Journal of biological chemistry, 286(30), 26987-95. PMID: 21646350  

Xie Z, & Klionsky DJ. (2007) Autophagosome formation: core machinery and adaptations. Nature cell biology, 9(10), 1102-9. PMID: 17909521  

von Muhlinen N, Akutsu M, Ravenhill BJ, Foeglein Á, Bloor S, Rutherford TJ, Freund SM, Komander D, & Randow F. (2012) LC3C, bound selectively by a noncanonical LIR motif in NDP52, is required for antibacterial autophagy. Molecular cell, 48(3), 329-42. PMID: 23022382  

Joubert PE, Werneke SW, de la Calle C, Guivel-Benhassine F, Giodini A, Peduto L, Levine B, Schwartz O, Lenschow DJ, & Albert ML. (2012) Chikungunya virus-induced autophagy delays caspase-dependent cell death. The Journal of experimental medicine, 209(5), 1029-47. PMID: 22508836  

Judith D, Mostowy S, Bourai M, Gangneux N, Lelek M, Lucas-Hourani M, Cayet N, Jacob Y, Prévost MC, Pierre P.... (2013) Species-specific impact of the autophagy machinery on Chikungunya virus infection. EMBO reports, 14(6), 534-44. PMID: 23619093  

  • August 31, 2014
  • 05:34 PM
  • 29 views

Mushroom extracts might prevent dental cavities

by Valerie Ashton in The Molecular Scribe

Recently published research suggests red camphor mushroom extracts might prevent the proliferation of bacteria that cause dental cavities and gum disease.... Read more »

  • August 31, 2014
  • 05:20 PM
  • 34 views

Heroin’s Anthrax Problem

by Rebecca Kreston in BODY HORRORS

Anthrax is a deadly disease with high rates of morbidity and mortality. Because it is, thankfully, also quite rare, it is relatively easy to track its whereabouts and going-ons when an outbreak occurs. Typically, outbreaks of anthrax have been traced to groups of people involved in high-risk activities involving grazing animals and their byproducts: anthrax favors shepherds, butchers, wool-sorters, leather workers, and even the odd drum-playing hippies. In 2009, however, an outbreak upended this........ Read more »

  • August 31, 2014
  • 02:38 PM
  • 36 views

New Synthetic Amino Acid for a New Class of Drugs

by Gabriel in Lunatic Laboratories

Creating new drug molecules is challenging, developing drugs that are highly effective against a target, but with minimal (or no) toxicity and side-effects to the patient can be an exercise in futility. These drug properties are directly conferred by the 3D structure of the drug molecule. So ideally, the drug should have a shape that is perfectly complementary to a disease-causing target, so that it binds it with high specificity.With that, scientists have developed a synthetic amino acid that c........ Read more »

Chen S. Gopalakrishnan R, Schaer T, Marger F, Hovius R, Bertrand D, Pojer F, Heinis C. (2014) Di-thiol amino acids can structurally shape and enhance the ligand-binding properties of polypeptides. Nature Chemistry. info:/10.1038/nchem.2043

  • August 30, 2014
  • 02:54 PM
  • 71 views

Direct mind-to-mind communication in humans

by Shelly Fan in Neurorexia

Image credit: www.techspot.com Here’s something right out of science fiction: a team of neuroscientists in Spain developed a system that allows a person to transmit the...... Read more »

Grau C, Ginhoux R, Riera A, Nguyen TL, Chauvat H, Berg M, Amengual JL, Pascual-Leone A, & Ruffini G. (2014) Conscious Brain-to-Brain Communication in Humans Using Non-Invasive Technologies. PloS one, 9(8). PMID: 25137064  

  • August 30, 2014
  • 02:23 PM
  • 44 views

Predictor of Sudden Death helps identify ICD candidates

by Gabriel in Lunatic Laboratories

New guidelines for patients with hypertrophic cardiomyopathy (HCM) identify candidates for implantable cardioverter defibrillators (ICDs). These devices help protect patients from arrhythmias (an irregular heartbeat) which can limit blood flow to vital organs, like the brain for example. Identifying which pacents would benefit from an ICD has been difficult. But the new guidelines, which were recently published, will help determine the patients most likely to benefit from ICDs by testing to see ........ Read more »

Perry M. Elliott, (Chairperson) (UK)*, Aris Anastasakis, (Greece), Michael A. Borger, (Germany), Martin Borggrefe, (Germany), Franco Cecchi, (Italy), Philippe Charron, (France), Albert Alain Hagege, (France), Antoine Lafont, (France), Giuseppe Limongelli,. (2014) 2014 ESC Guidelines on diagnosis and management of hypertrophic cardiomyopathy The Task Force for the Diagnosis and Management of Hypertrophic Cardiomyopathy of the European Society of Cardiology (ESC). European Heart Journal . info:/10.1093/eurheartj/ehu284

  • August 30, 2014
  • 08:12 AM
  • 51 views

The Myth Of “Roid Rage”?

by Neuroskeptic in Neuroskeptic_Discover

Are men who inject testosterone and other anabolic steroids at risk of entering a violent “roid rage“? Many people think so. Whenever a professional athlete commits a violent crime, it’s not long before someone suggests that steroids may have been involved. The most recent example of this is the case of Jonathan “War Machine” Koppenhaver. […]The post The Myth Of “Roid Rage”? appeared first on Neuroskeptic.... Read more »

  • August 30, 2014
  • 03:34 AM
  • 54 views

Under-recognised co-occurring conditions in autism

by Paul Whiteley in Questioning Answers

A brief post to direct you to the paper by Nicolaidis and colleagues [1] talking about primary care for adults on the autism spectrum and mention of an issue quite important to this blog: "the recognition of associated conditions"."When 900 years old you reach, look as good you will not".Alongside the announcement of what seems like an interesting workshop organised by the US IACC (Interagency Autism Coordinating Committee) titled: "IACC Workshop on Under-Recognized Co-Occurring Condit........ Read more »

Nicolaidis C, Kripke CC, & Raymaker D. (2014) Primary Care for Adults on the Autism Spectrum. The Medical clinics of North America, 98(5), 1169-1191. PMID: 25134878  

  • August 29, 2014
  • 08:36 PM
  • 42 views

Foot Orthotics and Patellofemoral Pain

by Craig Payne in Running Research Junkie

Foot Orthotics and Patellofemoral Pain... Read more »

  • August 29, 2014
  • 07:15 PM
  • 49 views

A change of mind: from bitter recollections to sweet memories

by Shelly Fan in Neurorexia

There are a LOT of articles on this study already, but most don’t go into the technical details – the part that, in my opinion,...... Read more »

  • August 29, 2014
  • 05:00 PM
  • 13 views

Visualizing the evolution of a scientific conference with altmetrics

by Peter Kraker in Science and the Web

From September 3 to 5, I will be attending STI 2014, the 19th International Conference on Science and Technology Indicators. There, I will present a paper entitled “Altmetrics-based Visualizations Depicting the Evolution of a Knowledge Domain” that I co-authored with Philipp Weißensteiner and Peter Brusilovsky (download the PDF here). In this work-in-progress paper, we present an approach to visualizing the topical evolution of a scientific conference over time.... Read more »

Kraker, P., Weißensteiner, P., & Brusilovsky, P. (2014) Altmetrics-based Visualizations Depicting the Evolution of a Knowledge Domain. 19th International Conference on Science and Technology Indicators (STI 2014), 330-333. info:/

  • August 29, 2014
  • 03:10 PM
  • 51 views

The Ever Mutating Ebola Virus

by Gabriel in Lunatic Laboratories

Ebola has a nasty reputation for the way it damages the body. It's rightfully earned when you look at the death rate. But when you look at the actual details of an Ebola infection, a surprising fact surfaces: The virus isn't what ends up killing you, it's your own immune system. Sure they are trying different ways to outsmart the virus, but it's mutating... quickly. In fact, scientists have rapidly sequenced and analyzed more than 99 Ebola virus genomes. The hope it to better understand the enem........ Read more »

Gire, S., Goba, A., Andersen, K., Sealfon, R., Park, D., Kanneh, L., Jalloh, S., Momoh, M., Fullah, M., Dudas, G.... (2014) Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak. Science. DOI: 10.1126/science.1259657  

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