New research shows that elephants get cancer less often than we do. But how can this help us........ Read more »
Abegglen, L., Caulin, A., Chan, A., Lee, K., Robinson, R., Campbell, M., Kiso, W., Schmitt, D., Waddell, P., Bhaskara, S.... (2015) Potential Mechanisms for Cancer Resistance in Elephants and Comparative Cellular Response to DNA Damage in Humans. JAMA, 1. DOI: 10.1001/jama.2015.13134
AG McCluskey. (2015) Trumpity-Trump!. Zongo's Cancer Diaries. info:/
Predatory Open Access publishers on the rise
open access, publishing, open access publishing, predators, predatory publishing, articles, peer review
The increase in so-called “predatory” Open Access publishers is posing a threat to the integrity of Open Access publishing. Predatory Open Access publishers charge authors high publishing fees without providing proper editorial and peer review services. They are abusing the opportunity created by the Gold Open Access publishing mod........ Read more »
Shen C, & Björk BC. (2015) 'Predatory' open access: a longitudinal study of article volumes and market characteristics. BMC medicine, 230. PMID: 26423063
The Centers for Disease Control and Prevention estimates that as many as 1.7 million people in the United States experience a traumatic brain injury (TBI) each year, over 15% of which are thought to be sports-related. Despite the relatively high prevalence of these injuries, however, it seems we are just beginning to appreciate the true extent of the effects they can have on the brain. Awareness of previously unrecognized consequences to TBI and repeated TBI--along with the realization that........ Read more »
Blennow, K., Hardy, J., & Zetterberg, H. (2012) The Neuropathology and Neurobiology of Traumatic Brain Injury. Neuron, 76(5), 886-899. DOI: 10.1016/j.neuron.2012.11.021
A thought-provoking new paper from Oxford neuroscientists Stephen Smith and colleagues reports a correlation between a certain pattern of brain activity and, well, a great many things.
The researchers took 461 resting state fMRI scans from the open Human Connectome Project (HCP) database. Associated with each scan is a set of 'meta-data' about the volunteer who had the scan. These 158 variables (listed here) cover everything from age and gender, to mental health status, income, and 'times use... Read more »
Smith SM, Nichols TE, Vidaurre D, Winkler AM, Behrens TE, Glasser MF, Ugurbil K, Barch DM, Van Essen DC, & Miller KL. (2015) A positive-negative mode of population covariation links brain connectivity, demographics and behavior. Nature Neuroscience. PMID: 26414616
"Children with ADHD [attention-deficit hyperactivity disorder] have a higher prevalence of asthma than the general Quebec pediatric population."So said the findings of the study by Grizenko and colleagues  adding to quite a volume of research potentially connecting the two conditions. During this latest foray into this area of research, researchers also observed that: "Children with ADHD born prematurely and/or those whose mothers experienced stress during pregnancy have a significa........ Read more »
Grizenko N, Osmanlliu E, Fortier MÈ, & Joober R. (2015) Increased Risk of Asthma in Children with ADHD: Role of Prematurity and Maternal Stress during Pregnancy. Journal of the Canadian Academy of Child and Adolescent Psychiatry , 24(2), 109-115. PMID: 26379722
Hormonal treatments administered as part of the procedures for sex reassignment have well-known and well-documented effects on the secondary sexual characteristics of the adult body, shifting a recipient’s physical appearance to that of the opposite sex. New research indicates that these hormonal treatments also alter brain chemistry.... Read more »
Kranz, G., Wadsak, W., Kaufmann, U., Savli, M., Baldinger, P., Gryglewski, G., Haeusler, D., Spies, M., Mitterhauser, M., Kasper, S.... (2015) High-Dose Testosterone Treatment Increases Serotonin Transporter Binding in Transgender People. Biological Psychiatry, 78(8), 525-533. DOI: 10.1016/j.biopsych.2014.09.010
This study came out of our group here at Morehouse School of Medicine. It concerns a mouse model of disrupted sleep in Angelman Syndrome. Basically, was it the circadian or homeostatic system that is responsible, or both? It was the homeostatic. ... Read more »
Ehlen, J., Jones, K., Pinckney, L., Gray, C., Burette, S., Weinberg, R., Evans, J., Brager, A., Zylka, M., Paul, K.... (2015) Maternal Ube3a Loss Disrupts Sleep Homeostasis But Leaves Circadian Rhythmicity Largely Intact. Journal of Neuroscience, 35(40), 13587-13598. DOI: 10.1523/JNEUROSCI.2194-15.2015
The Blue Brain project releases their first major paper today and boy, it’s a doozy. Including supplements, it’s over 100 pages long, including 40 figures and 6 tables. In order to properly understand everything in the paper, you have to go back … Continue reading →... Read more »
Markram et al. (2015) Reconstruction and Simulation of Neocortical Microcircuitry. Cell. info:/
Part II in our series looking at the scientific evidence behind sunscreen and skin cancer.... Read more »
van der Pols JC, Williams GM, Pandeya N, Logan V, & Green AC. (2006) Prolonged prevention of squamous cell carcinoma of the skin by regular sunscreen use. Cancer epidemiology, biomarkers , 15(12), 2546-8. PMID: 17132769
Lee TK, Rivers JK, & Gallagher RP. (2005) Site-specific protective effect of broad-spectrum sunscreen on nevus development among white schoolchildren in a randomized trial. Journal of the American Academy of Dermatology, 52(5), 786-92. PMID: 15858467
Koh HK, Geller AC, Miller DR, Grossbart TA, & Lew RA. (1996) Prevention and early detection strategies for melanoma and skin cancer. Current status. Archives of dermatology, 132(4), 436-43. PMID: 8629848
Leiter U, & Garbe C. (2008) Epidemiology of melanoma and nonmelanoma skin cancer--the role of sunlight. Advances in experimental medicine and biology, 89-103. PMID: 18348450
Brenner M, & Hearing VJ. (2008) The protective role of melanin against UV damage in human skin. Photochemistry and photobiology, 84(3), 539-49. PMID: 18435612
What do you think of when I say “luxury consumption”? Probably something that requires a Robin Leach voice over, right? Now what if I ask you why these luxuries are so valued? Is it because they are of excellent quality? Aesthetically appealing? Highly exclusive? Next, consider the audience for the luxury – who is admiring who? And what does that luxury symbolize? Status? Wealth? Success?A recent paper in Evolutionary Psychology takes a look at these questions and has one of the best title........ Read more »
Hudders, L., De Backer, C., Fisher, M., & Vyncke, P. (2014) The Rival Wears Prada: Luxury Consumption as a Female Competition Strategy. Evolutionary Psychology, 12(3). DOI: 10.1177/147470491401200306
Pine Cone and Peacocks from Vatican MuseumTestosterone displays effects on brain function in both males and females.Emanuela Mhillaj and colleagues recently published a nice summary of what is currently known about the effects of anabolic-androgen steroids (AAS) on the brain.Their review highlighted the potential for AAS to modulate brain reward function and potentially lead to a drug dependence type of abuse pattern.Here are some of my notes on their discussion of AAS and the brain reward syste........ Read more »
Mhillaj E, Morgese MG, Tucci P, Bove M, Schiavone S, & Trabace L. (2015) Effects of anabolic-androgens on brain reward function. Frontiers in neuroscience, 295. PMID: 26379484
Yates WR, Perry PJ, & Andersen KH. (1990) Illicit anabolic steroid use: a controlled personality study. Acta psychiatrica Scandinavica, 81(6), 548-50. PMID: 2378247
Tall people are more likely to get cancer......aren't they?... Read more »
AG McCluskey. (2015) Tough Luck, Stretch. Zongo's Cancer Diaries. info:/
My attention was grabbed recently by the paper published by Jon Kaiser  (open-access available here) detailing the results of a 'proof-of-concept investigation' examining the use of something called KPAX002 on a small number of participants diagnosed with Chronic Fatigue Syndrome (CFS).Looking at how KPAX002 - "a combination of low-dose methylphenidate hydrochloride and mitochondrial support nutrients currently under development by K-PAX Pharmaceuticals" - impacted on fatigue symptoms and "co........ Read more »
Kaiser JD. (2015) A prospective, proof-of-concept investigation of KPAX002 in chronic fatigue syndrome. International journal of clinical and experimental medicine, 8(7), 11064-74. PMID: 26379906
It is now well-established that social class is positively related to mental health. However, researchers remain unclear about the specific processes that underlie the relation between social class and depression. In some recent research, we investigated the potential roles of parenting style and friendship in explaining the relationship between social class and mental health.... Read more »
Rubin, M., & Kelly, B. (2015) A cross-sectional investigation of parenting style and friendship as mediators of the relation between social class and mental health in a university community. International Journal for Equity in Health, 14(1), 1-11. DOI: 10.1186/s12939-015-0227-2
MedicalResearch.com Interview with: Dr. Madeleine M A Tilanus-Linthorst PhD Department of Surgery Erasmus University Medical Centre – Cancer Institute Rotterdam, Netherlands Medical Research: What is the background for this study? Medical Research: Why is this study important? Response: This prospective … Continue reading →
The post Catching Breast Cancer Early Is Still Critical appeared first on MedicalResearch.com.
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Dr. Madeleine M A Tilanus-Linthorst PhD. (2015) Catching Breast Cancer Early Is Still Critical. MedicalResearch.com. info:/
Parents who are more anxious and emotional can impact the amount of violent video games their children play, according to new consumer research from Iowa State University. Russell Laczniak, a professor of marketing and the John and Connie Stafford Professor in Business, says given the harmful effects of violent video games, he and his colleagues wanted to better understand how parents influence children’s behavior.... Read more »
Walker, D., Laczniak, R., Carlson, L., & Brocato, E. (2015) Parenting Orientations as Antecedents of Children's Violent Videogame Play. Journal of Consumer Affairs. DOI: 10.1111/joca.12096
MedicalResearch.com Interview with: Ambarish Pandey, MD Cardiology Fellow, PGY5 University of Texas Southwestern Medical Center, Dallas, Texas 75390 Medical Research: What is the background for this study? What are the main findings? Dr. Berry: Physical inactivity is considered a major … Continue reading →
The post Heart Failure Risk Reduced With Increased Physical Activity appeared first on MedicalResearch.com.
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Ambarish Pandey, MD. (2015) Heart Failure Risk Reduced With Increased Physical Activity. MedicalResearch.com. info:/
MedicalResearch.com Interview with: Prof. Peter JD Andrews Honorary Professor Department of Anaesthesia University of Edinburgh Medical Research: What is the background for this study? Prof. Andrews: Therapeutic hypothermia has shown considerable promise as a neuro-protective intervention in many species and … Continue reading →
The post Hypothermia Did Not Improve Outcomes After Traumatic Brain Injury appeared first on MedicalResearch.com.
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Prof. Peter JD Andrews. (2015) Hypothermia Did Not Improve Outcomes After Traumatic Brain Injury. MedicalResearch.com. info:/
MedicalResearch.com Interview with: Holly G. Prigerson, Ph.D. Irving Sherwood Wright Professor in Geriatrics Professor of Sociology in Medicine Director, Center for Research on End of Life Care Weill Cornell Medical College New York Presbyterian Hospital New York City, New York … Continue reading →
The post Most Terminally Ill Cancer Patients Not Aware Of Their Life Expectancy appeared first on MedicalResearch.com.
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Holly G. Prigerson, Ph.D. (2015) Most Terminally Ill Cancer Patients Not Aware Of Their Life Expectancy. MedicalResearch.com. info:/
MedicalResearch.com Interview with: Michael M. McNeil, MD, MPH Centers for Disease Control and Prevention Atlanta, GA Medical Research: What is the background for this study? What are the main findings? Dr. McNeil : Anaphylaxis is an uncommon potentially life-threatening allergic reaction … Continue reading →
The post CDC Study Finds Anaphylaxis Rare After Vaccinations, With No Fatalities appeared first on MedicalResearch.com.
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Michael M. McNeil, MD, MPH. (2015) CDC Study Finds Anaphylaxis Rare After Vaccinations, With No Fatalities. MedicalResearch.com. info:/
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