Stephanie Swift

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  • February 14, 2014
  • 08:07 AM
  • 136 views

More evidence that red wine and aspirin protect against cancer

by Stephanie Swift in mmmbitesizescience

Cancer is a disease of genes. DNA mutations mess with the genetic content of a cell, enabling it to escape the normal controls that restrict their growth. Now, a team of scientists led by Delphine Lissa and Guido Kroemer at … Continue reading →... Read more »

Lissaa, D., Senovillaa, L., Rello-Varona, S., Vitalee, I., Michauda, M., Pietrocola, F., Boilèvea, A., Obrist, F., Bordenave, C, Garcia, P.... (2014) Resveratrol and aspirin eliminate tetraploid cells for anticancer chemoprevention. PNAS. DOI: 10.1073/pnas.1318440111  

  • February 3, 2014
  • 08:28 AM
  • 114 views

Bright Night Lights: Tracking Light Pollution from Space

by Stephanie Swift in mmmbitesizescience

The creep and sprawl of artificial urban lighting is probably the most pervasive technological innovation of the 20th century. Keeping track of how artificial light is changing Europe’s nightscape is important, since more light is typically associated with greater economic … Continue reading →... Read more »

  • January 17, 2014
  • 08:28 AM
  • 226 views

Where in the body do our emotions lie?

by Stephanie Swift in mmmbitesizescience

Emotions are strange things, bursting over us as we react to life’s joys and challenges. While they might be thought of as ethereal entities with no fixed form or function, emotions actually produce very tangible physical reactions throughout the body. … Continue reading →... Read more »

Nummenmaa L, Glerean E, Hari R, & Hietanen JK. (2013) Bodily maps of emotions. Proceedings of the National Academy of Sciences of the United States of America. PMID: 24379370  

  • December 23, 2013
  • 08:28 AM
  • 220 views

Antibiotics release death sugars that help bad bugs to grow

by Stephanie Swift in mmmbitesizescience

In the 1940’s, antibiotics were hailed as wonder drugs. “Syphilis is now curable!”, ran the posters. Yet in modern times, several dark sides of these drugs have come to light. The widespread overuse of antibiotic therapy has driven the emergence … Continue reading →... Read more »

Ng KM, Ferreyra JA, Higginbottom SK, Lynch JB, Kashyap PC, Gopinath S, Naidu N, Choudhury B, Weimer BC, Monack DM.... (2013) Microbiota-liberated host sugars facilitate post-antibiotic expansion of enteric pathogens. Nature, 502(7469), 96-9. PMID: 23995682  

  • November 19, 2013
  • 08:28 AM
  • 166 views

Chilly temperatures help cancers grow

by Stephanie Swift in mmmbitesizescience

At low temperatures, the human body has a hard time. As the cold sets in, blood vessels constrict to maintain heat and some body parts – like fingers and toes – begin to suffer. Metabolism ramps up to fight the … Continue reading →... Read more »

Kokolusa, KM, Capitanoa, ML, Leea, CT, Enga, JWL, Waighta, JD, Hylandera, BL, Sexton, S, Hong, CC, Gordon, CJ, Abrams, SI.... (2013) Baseline tumor growth and immune control in laboratory mice are significantly influenced by subthermoneutral housing temperature. PNAS. info:/10.1073/pnas.1304291110

  • November 9, 2013
  • 08:28 AM
  • 162 views

Creepy crawly centipedes are a source of new high-strength painkillers

by Stephanie Swift in mmmbitesizescience

I’m dreading the day I get knocked up, since I know that my incredibly low pain threshold will have trouble dealing with the crazy horror that is childbirth. That’s why I was overjoyed to hear of some new research from … Continue reading →... Read more »

Yang S, Xiao Y, Kang D, Liu J, Li Y, Undheim EA, Klint JK, Rong M, Lai R, & King GF. (2013) Discovery of a selective NaV1.7 inhibitor from centipede venom with analgesic efficacy exceeding morphine in rodent pain models. Proceedings of the National Academy of Sciences of the United States of America, 110(43), 17534-9. PMID: 24082113  

  • November 2, 2013
  • 01:01 PM
  • 204 views

Pumping out Petrol with Bioengineered Bugs

by Stephanie Swift in mmmbitesizescience

One of the terribly tricky questions in this ol’ world of ours is how to sustain a species that likes to extract toxic crude oil from the ground and use it in a way that’s disturbingly damaging to the environment … Continue reading →... Read more »

Choi YJ, & Lee SY. (2013) Microbial production of short-chain alkanes. Nature, 502(7472), 571-4. PMID: 24077097  

  • October 19, 2013
  • 09:28 AM
  • 172 views

“Grape-like aromas” keep mosquitoes at bay

by Stephanie Swift in mmmbitesizescience

The mosquito is my dad’s nemesis in the insect world. He will go to extraordinary lengths to secure his person from mosquito attack, roaming the corridors on night patrols and jamming mosquito repellent devices into every possible plug socket. Such … Continue reading →... Read more »

Kain, P, Boyle, SM, Tharadra, SK, Guda, T, Pham, C, Dahanukar, A, & Ray, A. (2013) Odour receptors and neurons for DEET and new insect repellents. Nature. info:/24089210

  • October 5, 2013
  • 09:28 AM
  • 152 views

How to: boost resistance to tuberculosis

by Stephanie Swift in mmmbitesizescience

Most kiddies receive the very effective Bacille Calmette-Guérin (BCG) vaccine against tuberculosis during childhood, but as they grow up, the protection afforded by this vaccine wanes. Since cases of adult TB are on the rise, receiving an immune upgrade would … Continue reading →... Read more »

  • September 7, 2013
  • 08:28 AM
  • 266 views

The fairly depressing picture of pesticide pollution in British rivers

by Stephanie Swift in mmmbitesizescience

Lots of pesticides – such as the organochlorine insecticide, DDT – that were widely used in the fairly recent past are now banned after having serious effects on the health of humans and other species. Yet old and new pollution … Continue reading →... Read more »

Morrissey CA, Stanton DW, Pereira MG, Newton J, Durance I, Tyler CR, & Ormerod SJ. (2013) Eurasian dipper eggs indicate elevated organohalogenated contaminants in urban rivers. Environmental science , 47(15), 8931-9. PMID: 23819781  

  • August 27, 2013
  • 08:28 AM
  • 279 views

Magnificently Mathematical Mussels

by Stephanie Swift in mmmbitesizescience

Despite the ease with which mussels can be cooked and eaten with chips, harvesting these tiny shelled bivalves from the seashore requires a certain amount of industrious prising. That’s because mussels use multiple thin byssus threads to securely fasten themselves … Continue reading →... Read more »

  • August 9, 2013
  • 08:28 AM
  • 191 views

Particle accelerators: making life better since 1932

by Stephanie Swift in mmmbitesizescience

Atoms form the building blocks of everything that exists in the world, holding chairs, rocks, water and our bodies together in strong, stable structures. But atoms themselves are made up of lots of composite parts, called sub-atomic particles. Such particles … Continue reading →... Read more »

  • August 1, 2013
  • 08:28 AM
  • 177 views

A Marvellous Month of Science

by Stephanie Swift in mmmbitesizescience

Taking vitamin supplements might not be as healthy as you think Antioxidant vitamins, like vitamin C and E, are thought to boost health by reducing the creation of DNA-damaging free radicals that can contribute to the ageing process. In lab … Continue reading →... Read more »

Tian X, Azpurua J, Hine C, Vaidya A, Myakishev-Rempel M, Ablaeva J, Mao Z, Nevo E, Gorbunova V, & Seluanov A. (2013) High-molecular-mass hyaluronan mediates the cancer resistance of the naked mole rat. Nature, 499(7458), 346-9. PMID: 23783513  

Amunts K, Lepage C, Borgeat L, Mohlberg H, Dickscheid T, Rousseau MÉ, Bludau S, Bazin PL, Lewis LB, Oros-Peusquens AM.... (2013) BigBrain: an ultrahigh-resolution 3D human brain model. Science (New York, N.Y.), 340(6139), 1472-5. PMID: 23788795  

  • July 19, 2013
  • 08:28 AM
  • 296 views

Clouds of decoy viruses help cure genetic disease

by Stephanie Swift in mmmbitesizescience

The presence of foreign objects, like viruses, in our bloodstream is usually a bad thing. Evolution has created some extremely efficient immune cells that patrol the blood, seeking out material that should not be there, and shutting it down. Sometimes, … Continue reading →... Read more »

Mingozzi, F., Anguela, X.M., Pavani, G., Chen, Y., Davidson, R.J., Hui, D.J., Yazicioglu, M., Elkouby, L., Hinderer, C.J., Faella, A.... (2013) Overcoming Preexisting Humoral Immunity to AAV Using Capsid Decoys. Science Translational Medicine, 5(194). info:/

  • July 17, 2013
  • 08:28 AM
  • 203 views

Gene therapy using stem cells prevents inherited diseases

by Stephanie Swift in mmmbitesizescience

Originally written for The Conversation. Genetic traits like a bulbous nose or balding give some people reasons to moan about what they inherited from their parents. But more serious genetic flaws can cause debilitating disease. Now, Italian researchers have come … Continue reading →... Read more »

Biffi A, Montini E, Lorioli L, Cesani M, Fumagalli F, Plati T, Baldoli C, Martino S, Calabria A, Canale S.... (2013) Lentiviral Hematopoietic Stem Cell Gene Therapy Benefits Metachromatic Leukodystrophy. Science (New York, N.Y.). PMID: 23845948  

Aiuti A, Biasco L, Scaramuzza S, Ferrua F, Cicalese MP, Baricordi C, Dionisio F, Calabria A, Giannelli S, Castiello MC.... (2013) Lentiviral Hematopoietic Stem Cell Gene Therapy in Patients with Wiskott-Aldrich Syndrome. Science (New York, N.Y.). PMID: 23845947  

  • July 8, 2013
  • 03:28 AM
  • 313 views

MESSENGER spacecraft helps uncover Mercury’s pummelled past

by Stephanie Swift in mmmbitesizescience

In our solar system, Mercury is the teeniest planet, and nestles closest to the sun. Understanding how Mercury developed as the solar system formed is an intriguing question for space science, and a surprising amount of information can be uncovered … Continue reading →... Read more »

  • June 29, 2013
  • 08:28 AM
  • 225 views

A huge variety of fungi call your feet home

by Stephanie Swift in mmmbitesizescience

Human skin is a hardy, water-resistant covering that keeps important biological stuff from falling out of the body. It’s also a camping ground for millions of bacteria (picked out in magenta, above), fungi (seen in blue-green, above) and yeast that … Continue reading →... Read more »

Findley K, Oh J, Yang J, Conlan S, Deming C, Meyer JA, Schoenfeld D, Nomicos E, Park M, NIH Intramural Sequencing Center Comparative Sequencing Program.... (2013) Topographic diversity of fungal and bacterial communities in human skin. Nature, 498(7454), 367-70. PMID: 23698366  

  • June 20, 2013
  • 08:28 AM
  • 260 views

Vaccine delivers an immune double whammy to fight tuberculosis

by Stephanie Swift in mmmbitesizescience

Vaccination is a hugely important public health intervention, perhaps the biggest in the history of mankind. While many childhood diseases are now effectively controlled by immunisation programs (as long as parents vaccinate their kids), there is still no effective vaccine … Continue reading →... Read more »

  • June 8, 2013
  • 09:28 AM
  • 248 views

Turning insect viruses into cancer therapies

by Stephanie Swift in mmmbitesizescience

Gene therapy is a pretty promising approach for lots of different diseases, and has already overcome a huge hurdle with the approval of the very first gene therapy product, Glybera, by the European Commission in 2012. At its core, gene … Continue reading →... Read more »

Swift, S., Rivera, G., Dussupt, V., Leadley, R., Hudson, L., MA de Ridder, C., Kraaij, R., Burns, J., Maitland, N., & Georgopoulos, L. (2013) Evaluating Baculovirus as a Vector for Human Prostate Cancer Gene Therapy. PLoS ONE, 8(6). DOI: 10.1371/journal.pone.0065557  

  • June 4, 2013
  • 08:28 AM
  • 226 views

Fish parasite inspires sticky surgical tissue patch

by Stephanie Swift in mmmbitesizescience

Surgeons still find it tricky to quickly and reliably stick a wet, slippery organ back together during invasive procedures. The currently available selection of ‘stick-you-together’ products – staples and chemical glues – do a decent job, but make a bit … Continue reading →... Read more »

Yang SY, O'Cearbhaill ED, Sisk GC, Park KM, Cho WK, Villiger M, Bouma BE, Pomahac B, & Karp JM. (2013) A bio-inspired swellable microneedle adhesive for mechanical interlocking with tissue. Nature communications, 1702. PMID: 23591869  

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