1 posts · 352 views
the Node
1 post
Sort by Latest Post, Most Popular
View by Condensed, Full
- December 2, 2011
- 11:07 PM
- 352 views
Senescent cell rejuvenation – you(r cells) are never too old for pluripotency!
by Sasha Terashima in the Node
In 2007, a group let by Takahashi and Yamanaka from Kyoto University successfully generated pluripotent cells from human adult fibroblasts. They were able to induce a pluripotent state in differentiated cells by introducing four transcription factors, OCT4, SOX2, c-MYC, and KLF4 by retroviral infection, hence the name “induced pluripotent stem cells (iPSCs).” Although the [...]... Read more »
Lapasset L, Milhavet O, Prieur A, Besnard E, Babled A, Aït-Hamou N, Leschik J, Pellestor F, Ramirez JM, De Vos J.... (2011) Rejuvenating senescent and centenarian human cells by reprogramming through the pluripotent state. Genes , 25(21), 2248-53. PMID: 22056670
topics
join us!
Do you write about peer-reviewed research in your blog? Use ResearchBlogging.org to make it easy for your readers — and others from around the world — to find your serious posts about academic research.
If you don't have a blog, you can still use our site to learn about fascinating developments in cutting-edge research from around the world.
