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United Academics Connects Science to Society.
The biotechnology tool known as CRISPR is making a big impact on medicine and other fields. It’s a collection of enzymes, originally found in the immune system of certain bacteria. One enzyme targets a particular gene, and its companion cuts out that section of DNA which may enable further changes.... Read more »
Tsai SQ, Wyvekens N, Khayter C, Foden JA, Thapar V, Reyon D, Goodwin MJ, Aryee MJ, & Joung JK. (2014) Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing. Nature biotechnology. PMID: 24770325
As a science editor for United Academics, a website that contains numerous popular scientific articles, I explored the website to find what components make science articles more attractive. I analyzed several articles that were frequently shared on social network sites. Here are eleven tips and tricks I filtered out of these articles:... Read more »
Parkinson, J., & Adendorff, R. (2004) The use of popular science articles in teaching scientific literacy. English for Specific Purposes, 23(4), 379-396. DOI: 10.1016/j.esp.2003.11.005
Urban laboratories can serve as new places for knowledge production and direct application with the goal of making cities more economically viable, socially robust and environmentally friendly.... Read more »
Evans, J., & Karvonen, A. (2014) ‘Give Me a Laboratory and I Will Lower Your Carbon Footprint!’ - Urban Laboratories and the Governance of Low-Carbon Futures. International Journal of Urban and Regional Research, 38(2), 413-430. DOI: 10.1111/1468-2427.12077
Recent outbreaks of Ebola virus in Guinea have made international news. Ebola virus was first identified in 1976 in the region that is now the Democratic Republic of the Congo in central Africa. The virus was named after the river near where it was found. Since 1976, there have been multiple outbreaks in central Africa, but this year is the first time that an outbreak has occurred as far west as Guinea and Sierra Leone.... Read more »
Qiu X, Wong G, Fernando L, Audet J, Bello A, Strong J, Alimonti JB, & Kobinger GP. (2013) mAbs and Ad-Vectored IFN-α therapy rescue ebola-infected nonhuman primates when administered after the detection of viremia and symptoms. Science translational medicine, 5(207). PMID: 24132638
Pettitt, J., Zeitlin, L., Kim, D., Working, C., Johnson, J., Bohorov, O., Bratcher, B., Hiatt, E., Hume, S., Johnson, A.... (2013) Therapeutic Intervention of Ebola Virus Infection in Rhesus Macaques with the MB-003 Monoclonal Antibody Cocktail. Science Translational Medicine, 5(199), 199-199. DOI: 10.1126/scitranslmed.3006608
Not that long ago, I heard about ginseng in my Plants’ Diversity class, but it was not given that much relevance. Soon after that, ginseng teas and supplements and a panoply of ginseng-made products appeared in the market. Then I finally realized I may not have given ginseng the importance it deserves.... Read more »
Lee JS, Hwang HS, Ko EJ, Lee YN, Kwon YM, Kim MC, & Kang SM. (2014) Immunomodulatory activity of red ginseng against influenza A virus infection. Nutrients, 6(2), 517-29. PMID: 24473234
The ultimate goal of all these projects is to be able to reconstruct the human brain – have a definitive computer model or a database of every neuron and its cell type and the connections between each individual cell. Is this feasible?... Read more »
A new study reveals that nanoparticles can break the rules of thermodynamic: what do these findings imply? An interview with one of the researchers. ... Read more »
Gieseler J, Quidant R, Dellago C, & Novotny L. (2014) Dynamic relaxation of a levitated nanoparticle from a non-equilibrium steady state. Nature nanotechnology. PMID: 24681775
Wang, G., Sevick, E., Mittag, E., Searles, D., & Evans, D. (2002) Experimental Demonstration of Violations of the Second Law of Thermodynamics for Small Systems and Short Time Scales. Physical Review Letters, 89(5). DOI: 10.1103/PhysRevLett.89.050601
In a study just published in Nature Medicine, researchers have identified a new mechanism that is at least in part responsible for the brain alterations caused by loss of mTORC1 in patients suffering from Major Depressive Disorder.... Read more »
Ota KT, Liu RJ, Voleti B, Maldonado-Aviles JG, Duric V, Iwata M, Dutheil S, Duman C, Boikess S, Lewis DA.... (2014) REDD1 is essential for stress-induced synaptic loss and depressive behavior. Nature medicine. PMID: 24728411
New DNA study reveals lion history and could guide conservation efforts.... Read more »
Barnett R, Yamaguchi N, Shapiro B, Ho SY, Barnes I, Sabin R, Werdelin L, Cuisin J, & Larson G. (2014) Revealing the maternal demographic history of Panthera leo using ancient DNA and a spatially explicit genealogical analysis. BMC evolutionary biology, 14(1), 70. PMID: 24690312
A new study reveals the role of sugars as initial regulator of apical dominance... Read more »
Mason MG, Ross JJ, Babst BA, Wienclaw BN, & Beveridge CA. (2014) Sugar demand, not auxin, is the initial regulator of apical dominance. Proceedings of the National Academy of Sciences of the United States of America. PMID: 24711430
Most researchers and clinicians think that making axons re-grow is an impossible task. But injecting a molecule named PCAF offers hope, as new research shows.... Read more »
Puttagunta R, Tedeschi A, Sória MG, Hervera A, Lindner R, Rathore KI, Gaub P, Joshi Y, Nguyen T, Schmandke A.... (2014) PCAF-dependent epigenetic changes promote axonal regeneration in the central nervous system. Nature communications, 3527. PMID: 24686445
Narcissism plays a key role in the excessive executive pay culture. What is the impact of having a narcissist at the head of a company?
... Read more »
Chatterjee, A. and Hambrick, D. C. (2007) It's All about Me: Narcissistic Chief Executive Officers and Their Effects on Company Strategy and Performance. Administrative Science Quarterly. DOI: 52(3):351-386
Wide-ranging analysis shows a decreased transmission intensity in the last decade... Read more »
Noor AM, Kinyoki DK, Mundia CW, Kabaria CW, Mutua JW, Alegana VA, Fall IS, & Snow RW. (2014) The changing risk of Plasmodium falciparum malaria infection in Africa: 2000-10: a spatial and temporal analysis of transmission intensity. Lancet. PMID: 24559537
Cotter C, Sturrock HJ, Hsiang MS, Liu J, Phillips AA, Hwang J, Gueye CS, Fullman N, Gosling RD, & Feachem RG. (2013) The changing epidemiology of malaria elimination: new strategies for new challenges. Lancet, 382(9895), 900-11. PMID: 23594387
Mosso’s 19th century experiments in cerebral blood flow dynamics found and reproduced.... Read more »
Field, D., & Inman, L. (2014) Weighing brain activity with the balance: a contemporary replication of Angelo Mosso's historical experiment. Brain, 137(2), 634-639. DOI: 10.1093/brain/awt352
Sandrone, S., Bacigaluppi, M., Galloni, M., Cappa, S., Moro, A., Catani, M., Filippi, M., Monti, M., Perani, D., & Martino, G. (2013) Weighing brain activity with the balance: Angelo Mosso's original manuscripts come to light. Brain, 137(2), 621-633. DOI: 10.1093/brain/awt091
Recent study shows incidental emotions change others' reciprocity in trusting situations.... Read more »
Kausel, E., & Connolly, T. (2014) Do people have accurate beliefs about the behavioral consequences of incidental emotions? Evidence from trust games. Journal of Economic Psychology. DOI: 10.1016/j.joep.2014.02.002
New research suggests gene FAT10 would reduce energy metabolism, increase susceptibility to inflammatory states and promote obesity and age-related diseases.... Read more »
Canaan, A., DeFuria, J., Perelman, E., Schultz, V., Seay, M., Tuck, D., Flavell, R., Snyder, M., Obin, M., & Weissman, S. (2014) Extended lifespan and reduced adiposity in mice lacking the FAT10 gene. Proceedings of the National Academy of Sciences. DOI: 10.1073/pnas.1323426111
Music seems of great significance for many. It makes us dance, cheers us up, makes us cry; accompanying us through happy and sad life events. 5 facts give insight in the human love for music.... Read more »
Salimpoor VN, Benovoy M, Larcher K, Dagher A, & Zatorre RJ. (2011) Anatomically distinct dopamine release during anticipation and experience of peak emotion to music. Nature neuroscience, 14(2), 257-62. PMID: 21217764
If you are used to have a pet, it is even likely for you to understand what your non- human friend is telling you. This ability to correctly identify the feelings of other people or other animals is called voice- induced emotional recognition.... Read more »
Scheumann M, Hasting AS, Kotz SA, & Zimmermann E. (2014) The Voice of Emotion across Species: How Do Human Listeners Recognize Animals' Affective States?. PloS one, 9(3). PMID: 24621604
The term ’gene editing’ sounds like something out of a science fiction movie. It seems like something that would be used in a plot to create a master race or defeat alien attackers. In reality, scientists are using this technique to treat diseases that currently have no cure. Earlier this month, a group from the University of Pennsylvania published an article in the New England Journal of Medicine in which they used gene editing to treat patients with human immunodeficiency virus (HIV).... Read more »
Tebas P, Stein D, Tang WW, Frank I, Wang SQ, Lee G, Spratt SK, Surosky RT, Giedlin MA, Nichol G.... (2014) Gene editing of CCR5 in autologous CD4 T cells of persons infected with HIV. The New England journal of medicine, 370(10), 901-10. PMID: 24597865
In a recent review in Nature Reviews Neurology, Sharp et al. have discussed the possibility of using network level analysis to further understand effects of TBI and hopefully develop treatment methods.... Read more »
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