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Susan Steinhardt
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by Susan Steinhardt in BioData Blogs
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WAKEFIELD, A., MURCH, S., ANTHONY, A., LINNELL, J., CASSON, D., MALIK, M., BERELOWITZ, M., DHILLON, A., THOMSON, M., & HARVEY, P. (1998) Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children. The Lancet, 351(9103), 637-641. DOI: 10.1016/S0140-6736(97)11096-0
by Susan Steinhardt in BioData Blogs
Our weekly compilation of science news for the week of July 19, 2009.... Read more »
Ciolino, J., Hoare, T., Iwata, N., Behlau, I., Dohlman, C., Langer, R., & Kohane, D. (2009) A Drug-Eluting Contact Lens. Investigative Ophthalmology , 50(7), 3346-3352. DOI: 10.1167/iovs.08-2826
Gottlieb, B., Chalifour, L., Mitmaker, B., Sheiner, N., Obrand, D., Abraham, C., Meilleur, M., Sugahara, T., Bkaily, G., & Schweitzer, M. (2009) BAK1 gene variation and abdominal aortic aneurysms. Human Mutation, 30(7), 1043-1047. DOI: 10.1002/humu.21046
by Susan Steinhardt in BioData Blogs
Our weekly compilation of science news for the week of September 13, 2009.... Read more »
Tingley, M., Monahan, W., Beissinger, S., & Moritz, C. (2009) Biogeography, Changing Climates, and Niche Evolution Sackler Colloquium: Birds track their Grinnellian niche through a century of climate change. Proceedings of the National Academy of Sciences. DOI: 10.1073/pnas.0901562106
Parks, A., Li, Z., Shi, Q., Owens, R., Jin, M., & Peters, J. (2009) Transposition into Replicating DNA Occurs through Interaction with the Processivity Factor. Cell, 138(4), 685-695. DOI: 10.1016/j.cell.2009.06.011
Gascoyne, D., Long, E., Veiga-Fernandes, H., de Boer, J., Williams, O., Seddon, B., Coles, M., Kioussis, D., & Brady, H. (2009) The basic leucine zipper transcription factor E4BP4 is essential for natural killer cell development. Nature Immunology. DOI: 10.1038/ni.1787
by Susan Steinhardt in BioData Blogs
Our weekly compilation of science news for the week of July 12, 2009.... Read more »
Bluher, M., Bashan, N., Shai, I., Harman-Boehm, I., Tarnovscki, T., Avinaoch, E., Stumvoll, M., Dietrich, A., Kloting, N., & Rudich, A. (2009) Activated Ask1-MKK4-p38MAPK/JNK Stress Signaling Pathway in Human Omental Fat Tissue May Link Macrophage Infiltration to Whole-Body Insulin Sensitivity. Journal of Clinical Endocrinology , 94(7), 2507-2515. DOI: 10.1210/jc.2009-0002
Tsang, V., Yacoub, M., Sridharan, S., Burch, M., Radley-Smith, R., Khaghani, A., Savoldo, B., & Amrolia, P. (2009) Late donor cardiectomy after paediatric heterotopic cardiac transplantation. The Lancet. DOI: 10.1016/S0140-6736(09)61201-0
Rex, C., Chen, L., Sharma, A., Liu, J., Babayan, A., Gall, C., & Lynch, G. (2009) Different Rho GTPase-dependent signaling pathways initiate sequential steps in the consolidation of long-term potentiation. The Journal of Cell Biology, 186(1), 85-97. DOI: 10.1083/jcb.200901084
Bonneville, S., Smits, M., Brown, A., Harrington, J., Leake, J., Brydson, R., & Benning, L. (2009) Plant-driven fungal weathering: Early stages of mineral alteration at the nanometer scale. Geology, 37(7), 615-618. DOI: 10.1130/G25699A.1
Kritzer, J., Hamamichi, S., McCaffery, J., Santagata, S., Naumann, T., Caldwell, K., Caldwell, G., & Lindquist, S. (2009) Rapid selection of cyclic peptides that reduce α-synuclein toxicity in yeast and animal models. Nature Chemical Biology. DOI: 10.1038/nchembio.193
Edelman, A., Carlson, N., Cherala, G., Munar, M., Stouffer, R., Cameron, J., Stanczyk, F., & Jensen, J. (2009) Impact of obesity on oral contraceptive pharmacokinetics and hypothalamic–pituitary–ovarian activity☆. Contraception. DOI: 10.1016/j.contraception.2009.04.011
by Susan Steinhardt in BioData Blogs
Known for his work in plant aquaporins, Dr. Menachem Moshelion has published many papers concerning his research. He has been running a lab for the past five years at Hebrew University’s Institute of Plant Sciences and Genetics in Agriculture located in Rehovot.... Read more »
KALDENHOFF, R., BERTL, A., OTTO, B., MOSHELION, M., & UEHLEIN, N. (2007) Characterization of Plant Aquaporins. Methods in Enzymology, 505-531. DOI: 10.1016/S0076-6879(07)28028-0
by Susan Steinhardt in BioData Blogs
Our weekly compilation of science news for the week of August 2, 2009.... Read more »
Liu, M., Kuan, Y., Wang, J., Hen, R., & Gershon, M. (2009) 5-HT4 Receptor-Mediated Neuroprotection and Neurogenesis in the Enteric Nervous System of Adult Mice. Journal of Neuroscience, 29(31), 9683-9699. DOI: 10.1523/JNEUROSCI.1145-09.2009
Paaijmans, K., Read, A., & Thomas, M. (2009) Understanding the link between malaria risk and climate. Proceedings of the National Academy of Sciences. DOI: 10.1073/pnas.0903423106
Plantier, J., Leoz, M., Dickerson, J., De Oliveira, F., Cordonnier, F., Lemée, V., Damond, F., Robertson, D., & Simon, F. (2009) A new human immunodeficiency virus derived from gorillas. Nature Medicine. DOI: 10.1038/nm.2016
Jean, Y., Chen, W., Sung, C., Duh, C., Huang, S., Lin, C., Tai, M., Tzeng, S., & Wen, Z. (2009) Capnellene, a natural marine compound derived from soft coral, attenuates chronic constriction injury-induced neuropathic pain in rats. British Journal of Pharmacology. DOI: 10.1111/j.1476-5381.2009.00323.x
Alto, L., Havton, L., Conner, J., Hollis II, E., Blesch, A., & Tuszynski, M. (2009) Chemotropic guidance facilitates axonal regeneration and synapse formation after spinal cord injury. Nature Neuroscience. DOI: 10.1038/nn.2365
Xu, Z., Gong, Q., Xia, B., Groves, B., Zimmermann, M., Mugler, C., Mu, D., Matsumoto, B., Seaman, M., & Ma, D. (2009) A role of histone H3 lysine 4 methyltransferase components in endosomal trafficking. The Journal of Cell Biology. DOI: 10.1083/jcb.200902146
Gregory, T., Andrews, C., McGuire, J., & Witt, C. (2009) The smallest avian genomes are found in hummingbirds. Proceedings of the Royal Society B: Biological Sciences. DOI: 10.1098/rspb.2009.1004
by Susan Steinhardt in BioData Blogs
Referred to as “the most significant scientific discovery of recent time,” Darwinius masillae also referred to as “Ida” has created quite a media frenzy. “The Missing Link,” Ida is a 47-million-year old female adapid primate discovered in the well known Messel deposits in Germany. The discovery has resulted in a flurry of promotional activity beginning with an elaborate event at The American Museum of Natural History, as well as a History Channel documentary, ........ Read more »
Franzen, J., Gingerich, P., Habersetzer, J., Hurum, J., von Koenigswald, W., & Smith, B. (2009) Complete Primate Skeleton from the Middle Eocene of Messel in Germany: Morphology and Paleobiology. PLoS ONE, 4(5). DOI: 10.1371/journal.pone.0005723
by Susan Steinhardt in BioData Blogs
Our weekly compilation of science news for the week of July 5, 2009.... Read more »
Bao, X., Kobayashi, M., Hatakeyama, S., Angata, K., Gullberg, D., Nakayama, J., Fukuda, M., & Fukuda, M. (2009) Tumor suppressor function of laminin-binding -dystroglycan requires a distinct 3-N-acetylglucosaminyltransferase. Proceedings of the National Academy of Sciences. DOI: 10.1073/pnas.0904515106
Winebrake, J., Corbett, J., Green, E., Lauer, A., & Eyring, V. (2009) Mitigating the Health Impacts of Pollution from Oceangoing Shipping: An Assessment of Low-Sulfur Fuel Mandates. Environmental Science , 43(13), 4776-4782. DOI: 10.1021/es803224q
Goodson, J., Groppo, D., Halem, S., & Carpino, E. (2009) Is Obesity an Oral Bacterial Disease?. Journal of Dental Research, 88(6), 519-523. DOI: 10.1177/0022034509338353
by Susan Steinhardt in BioData Blogs
In a survey commissioned by BioData, 94 researchers from 74 institutions worldwide were asked a series of questions regarding their management of research data. The survey’s purpose was to learn about and prove the need for knowledge management systems in academic research. 80% of the researchers surveyed believe their labs are not run efficiently.... Read more »
Noble, W. (2009) A Quick Guide to Organizing Computational Biology Projects. PLoS Computational Biology, 5(7). DOI: 10.1371/journal.pcbi.1000424
by Susan Steinhardt in BioData Blogs
Our weekly compilation of science news for the week of June 28, 2009.... Read more »
Smolen, J., Kay, J., Doyle, M., Landewé, R., Matteson, E., Wollenhaupt, J., Gaylis, N., Murphy, F., Neal, J., & Zhou, Y. (2009) Golimumab in patients with active rheumatoid arthritis after treatment with tumour necrosis factor α inhibitors (GO-AFTER study): a multicentre, randomised, double-blind, placebo-controlled, phase III trial. The Lancet. DOI: 10.1016/S0140-6736(09)60506-7
Purcell, S., Wray, N., Stone, J., Visscher, P., O'Donovan, M., Sullivan, P., Sklar, P., Purcell (Leader), S., Stone, J., Sullivan, P.... (2009) Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature. DOI: 10.1038/nature08185
Kragl, M., Knapp, D., Nacu, E., Khattak, S., Maden, M., Epperlein, H., & Tanaka, E. (2009) Cells keep a memory of their tissue origin during axolotl limb regeneration. Nature, 460(7251), 60-65. DOI: 10.1038/nature08152
Hesseling, A. (2009) Disseminated bacille Calmette-Guerin disease in HIV-infected South African infants. Bulletin of the World Health Organization, 87(7), 505-511. DOI: 10.2471/BLT.08.055657
by Susan Steinhardt in BioData Blogs
Our weekly compilation of science news for the week of July 26, 2009.... Read more »
Feuerer, M., Herrero, L., Cipolletta, D., Naaz, A., Wong, J., Nayer, A., Lee, J., Goldfine, A., Benoist, C., Shoelson, S.... (2009) Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters. Nature Medicine. DOI: 10.1038/nm.2002
Kajimura, S., Seale, P., Kubota, K., Lunsford, E., Frangioni, J., Gygi, S., & Spiegelman, B. (2009) Initiation of myoblast to brown fat switch by a PRDM16–C/EBP-β transcriptional complex. Nature. DOI: 10.1038/nature08262
Orso, G., Pendin, D., Liu, S., Tosetto, J., Moss, T., Faust, J., Micaroni, M., Egorova, A., Martinuzzi, A., McNew, J.... (2009) Homotypic fusion of ER membranes requires the dynamin-like GTPase Atlastin. Nature. DOI: 10.1038/nature08280
Page, R., Ambady, S., Holmes, W., Vilner, L., Kole, D., Kashpur, O., Huntress, V., Vojtic, I., Whitton, H., & Dominko, T. (2009) Induction of Stem Cell Gene Expression in Adult Human Fibroblasts without Transgenes. Cloning and Stem Cells, 2147483647. DOI: 10.1089/clo.2009.0015
Gentleman, E., Swain, R., Evans, N., Boonrungsiman, S., Jell, G., Ball, M., Shean, T., Oyen, M., Porter, A., & Stevens, M. (2009) Comparative materials differences revealed in engineered bone as a function of cell-specific differentiation. Nature Materials. DOI: 10.1038/nmat2505
by Susan Steinhardt in BioData Blogs
Our weekly compilation of science news for the week of June 21, 2009.... Read more »
Elia, J., Gai, X., Xie, H., Perin, J., Geiger, E., Glessner, J., D'arcy, M., deBerardinis, R., Frackelton, E., Kim, C.... (2009) Rare structural variants found in attention-deficit hyperactivity disorder are preferentially associated with neurodevelopmental genes. Molecular Psychiatry. DOI: 10.1038/mp.2009.57
Rabl, R., Soubannier, V., Scholz, R., Vogel, F., Mendl, N., Vasiljev-Neumeyer, A., Korner, C., Jagasia, R., Keil, T., Baumeister, W.... (2009) Formation of cristae and crista junctions in mitochondria depends on antagonism between Fcj1 and Su e/g. The Journal of Cell Biology, 185(6), 1047-1063. DOI: 10.1083/jcb.200811099
Iwahashi, C., Tassone, F., Hagerman, R., Yasui, D., Parrott, G., Nguyen, D., Mayeur, G., & Hagerman, P. (2009) A Quantitative ELISA Assay for the Fragile X Mental Retardation 1 Protein. Journal of Molecular Diagnostics, 11(4), 281-289. DOI: 10.2353/jmoldx.2009.080118
Ghosh, D., Mishra, M., Das, S., Kaushik, D., & Basu, A. (2009) Tobacco carcinogen induces microglial activation and subsequent neuronal damage. Journal of Neurochemistry. DOI: 10.1111/j.1471-4159.2009.06203.x
McAloose, D., & Newton, A. (2009) Wildlife cancer: a conservation perspective. Nature Reviews Cancer, 9(7), 517-526. DOI: 10.1038/nrc2665
by Susan Steinhardt in BioData Blogs
Hana Kucera has always had an interest in science. Kucera credits her scientific fascination to her parents who first introduced her to the observation, exploration and study of living things in their natural habitats. She graduated from British Columbia’s Simon Fraser University in 2004 with a B.Sc. in Biology. As a Master’s student at the University of New Brunswick in the fall of 2004, Kucera began her research in Dr. Gary Saunders’ lab studying the diversity of marine intertidal seawee........ Read more »
Kucera, H., & Saunders, G. (2008) Assigning morphological variants of Fucus (Fucales, Phaeophyceae) in Canadian waters to recognized species using DNA barcoding. Botany, 86(9), 1065-1079. DOI: 10.1139/B08-056
by Susan Steinhardt in BioData Blogs
Our weekly compilation of science news for the week of September 6, 2009.... Read more »
Schnuelle P, Gottmann U, Hoeger S, Boesebeck D, Lauchart W, Weiss C, Fischereder M, Jauch KW, Heemann U, Zeier M.... (2009) Effects of donor pretreatment with dopamine on graft function after kidney transplantation: a randomized controlled trial. JAMA : the journal of the American Medical Association, 302(10), 1067-75. PMID: 19738091
Münch, T., da Silveira, R., Siegert, S., Viney, T., Awatramani, G., & Roska, B. (2009) Approach sensitivity in the retina processed by a multifunctional neural circuit. Nature Neuroscience. DOI: 10.1038/nn.2389
Zelada-Guillén, G., Riu, J., Düzgün, A., & Rius, F. (2009) Immediate Detection of Living Bacteria at Ultralow Concentrations Using a Carbon Nanotube Based Potentiometric Aptasensor. Angewandte Chemie International Edition. DOI: 10.1002/anie.200902090
Childs, R., Palma, A., Wharton, S., Matrosovich, T., Liu, Y., Chai, W., Campanero-Rhodes, M., Zhang, Y., Eickmann, M., Kiso, M.... (2009) Receptor-binding specificity of pandemic influenza A (H1N1) 2009 virus determined by carbohydrate microarray. Nature Biotechnology, 27(9), 797-799. DOI: 10.1038/nbt0909-797
by Susan Steinhardt in BioData Blogs
Scientists at the University of California in San Diego (UCSD) Scripps Institution of Oceanography led by biological oceanographer David Checkley, have recently discovered that the high levels of carbon dioxide in the oceans are causing mutations in fish, specifically affecting the bones in a fish’s ear.... Read more »
Checkley, D., Dickson, A., Takahashi, M., Radich, J., Eisenkolb, N., & Asch, R. (2009) Elevated CO2 Enhances Otolith Growth in Young Fish. Science, 324(5935), 1683-1683. DOI: 10.1126/science.1169806
by Susan Steinhardt in BioData Blogs
Christie Wilcox is now passionate toward conservation biology, although she didn’t originally start off that way. While she always had an affinity to nature and animals, she didn’t realize that she wanted to be a biologist until she “stumbled” upon it in college. “When I’m at the beach and everyone is running away from jellyfish, I get excited and run up closer to check it out!”... Read more »
Smith, N., Wilcox, C., & Lessmann, J. (2009) Fiddler crab burrowing affects growth and production of the white mangrove (Laguncularia racemosa) in a restored Florida coastal marsh. Marine Biology. DOI: 10.1007/s00227-009-1253-7
by Susan Steinhardt in BioData Blogs
All she needed to know to fall in love with molecular biology, Dr. Tora Smulders-Srinivasan learned at 15 years old, in her tenth grade biology class. While she had been aware of basic hereditary concepts, Tora hadn’t been exposed to DNA, genetics, RNA, translation, or transcription until then. In that classroom, Tora says, she fell in love. “I loved the whole idea of DNA. The fact that there is a molecule that transfers between generations – and that is what sets up the whole organism. I........ Read more »
Smulders-Srinivasan TK, & Lin H. (2003) Screens for piwi suppressors in Drosophila identify dosage-dependent regulators of germline stem cell division. Genetics, 165(4), 1971-91. PMID: 14704180
by Susan Steinhardt in BioData Blogs
Our weekly compilation of science news for the week of September 20, 2009.... Read more »
Duris, J., Haack, S., & Fogarty, L. (2009) Gene and Antigen Markers of Shiga-toxin Producing E. coli from Michigan and Indiana River Water: Occurrence and Relation to Recreational Water Quality Criteria. Journal of Environmental Quality, 38(5), 1878-1886. DOI: 10.2134/jeq2008.0225
Behan, J., Yun, J., Proektor, M., Ehsanipour, E., Arutyunyan, A., Moses, A., Avramis, V., Louie, S., Butturini, A., Heisterkamp, N.... (2009) Adipocytes Impair Leukemia Treatment in Mice. Cancer Research. DOI: 10.1158/0008-5472.CAN-09-0800
Cenna, J., Hunter, M., Tan, G., Papaneri, A., Ribka, E., Schnell, M., Marx, P., & McGettigan, J. (2009) Replication‐Deficient Rabies Virus–Based Vaccines Are Safe and Immunogenic in Mice and Nonhuman Primates. The Journal of Infectious Diseases, 200(8), 1251-1260. DOI: 10.1086/605949
by Susan Steinhardt in BioData Blogs
Laboratory notebooks are essential for reproducing experiments. For years we have been raised in our labs knowing that every action must be written down in our lab notebook.... Read more »
Service, R. (2009) A Dark Tale Behind Two Retractions. Science, 326(5960), 1610-1611. DOI: 10.1126/science.326.5960.1610
by Susan Steinhardt in BioData Blogs
In June I commented on the autism - vaccine controversy and the role that Oprah had in promoting it. Seven moths later, I am revisiting this issue. 12 years ago, Andrew Wakefield and his colleagues first published his findings in The Lancet providing ‘evidence’ suggesting they had tracked down a shocking cause of autism – that being the MMR Vaccine. Last week The Lancet published a retraction of Wakefield’s paper stating that “it has become clear that several elements of the 1998 paper........ Read more »
WAKEFIELD, A., MURCH, S., ANTHONY, A., LINNELL, J., CASSON, D., MALIK, M., BERELOWITZ, M., DHILLON, A., THOMSON, M., & HARVEY, P. (1998) Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children. The Lancet, 351(9103), 637-641. DOI: 10.1016/S0140-6736(97)11096-0
The Editors of The Lancet, . (2010) Retraction—Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children. The Lancet, 375(9713), 445-445. DOI: 10.1016/S0140-6736(10)60175-4
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