31 posts · 32,085 views
Musings of a Scepticemic Oslerphile.
Pranab Chatterjee
31 posts
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- May 20, 2011
- 05:00 PM
- 1,648 views
Prophylactic Adrenaline for Anti Snake Venom Induced Anaphylaxis
by Pranab Chatterjee in Scepticemia
A discussion of a peer reviewed publication in PLoS Medicine regarding the use of Prophylactic Adrenaline for prevention of Anti snake venom indiced anaphylaxis.... Read more »
de Silva, H., Pathmeswaran, A., Ranasinha, C., Jayamanne, S., Samarakoon, S., Hittharage, A., Kalupahana, R., Ratnatilaka, G., Uluwatthage, W., Aronson, J.... (2011) Low-Dose Adrenaline, Promethazine, and Hydrocortisone in the Prevention of Acute Adverse Reactions to Antivenom following Snakebite: A Randomised, Double-Blind, Placebo-Controlled Trial. PLoS Medicine, 8(5). DOI: 10.1371/journal.pmed.1000435
- April 18, 2011
- 05:05 PM
- 1,273 views
House M.D. 1.02: Denialism
by Pranab Chatterjee in Scepticemia
Once you have read the plot, you will understand what I am going to deal with in this post. The key to understanding how House reached a diagnosis of SSPE in the adopted kid was in a funny encounter he … Continue reading →... Read more »
McKee, M., & Diethelm, P. (2010) How the growth of denialism undermines public health. BMJ, 341(dec14 1). DOI: 10.1136/bmj.c6950
- April 12, 2011
- 10:26 AM
- 1,127 views
House MD 1.01: Dignity in Death
by Pranab Chatterjee in Scepticemia
This is the first post in the new series on the blog where I analyze House MD episodes based on the content and scientific interpretation of the same. It is going to be a difficult ride trying to analyze a … Continue reading →... Read more »
Smith, K., Goy, E., Harvath, T., & Ganzini, L. (2011) Quality of Death and Dying in Patients who Request Physician-Assisted Death. Journal of Palliative Medicine, 14(4), 445-450. DOI: 10.1089/jpm.2010.0425
- March 25, 2011
- 01:33 AM
- 1,349 views
Buck-teria!
by Pranab Chatterjee in Scepticemia
First up, a disclaimer. I know one of the researchers who conducted this short study personally and professionally. I admire their work and what they have done to further the cause of promoting research by medical students in India. So, … Continue reading →... Read more »
Sharma A, Dhanashree B. (2011) Screening of currency in circulation for bacterial contamination. . Current Science, 100(6), 822-825. info:other/
- March 21, 2011
- 05:00 AM
- 1,143 views
Sex and the Senile
by Pranab Chatterjee in Scepticemia
Playtime! Geriatric sexuality is a very sparsely explored domain in the medical arena. With the developing world getting top heavy on the age pyramid, this has become a rather timely question to ask. This study conducted in Australia takes a … Continue reading →... Read more »
Hyde Z, Flicker L, Hankey GJ, Almeida OP, McCaul KA, Chubb SA, & Yeap BB. (2010) Prevalence of sexual activity and associated factors in men aged 75 to 95 years: a cohort study. Annals of internal medicine, 153(11), 693-702. PMID: 21135292
- March 11, 2011
- 03:40 AM
- 936 views
Tears = Turn Off
by Pranab Chatterjee in Scepticemia
How many of us have been reduced to blubbering idiots by the tears of a distressed damsel? I am sure the casualties are too many to put a number. Almost all of us have come across a time when we … Continue reading →... Read more »
Gelstein, S., Yeshurun, Y., Rozenkrantz, L., Shushan, S., Frumin, I., Roth, Y., & Sobel, N. (2011) Human Tears Contain a Chemosignal. Science, 331(6014), 226-230. DOI: 10.1126/science.1198331
- February 21, 2011
- 01:32 PM
- 1,234 views
Did Chopin Have Temporal Lobe Epilepsy?
by Pranab Chatterjee in Scepticemia
Frederick Chopin is not only one of the greatest composers this side of history, but also, a paleopathologist’s delight. He died at the age of 39, which, even by the standards of those days, was quite young. There were several … Continue reading →... Read more »
Vazquez Caruncho, M., & Branas Fernandez, F. (2011) The hallucinations of Frederic Chopin. Medical Humanities. DOI: 10.1136/jmh.2010.005405
- January 21, 2011
- 10:55 AM
- 1,654 views
Florbetapir: Making AD A Costlier Affair
by Pranab Chatterjee in Scepticemia
The FDA has conditionally approved the novel contrast agent, Florbetapir, to help in the diagnosis of amyloid beta plaque build up in the brains of Alzheimer’s (or, for that purpose, any damn dementia) patients. Now there are several reasons why … Continue reading →... Read more »
Wong, D., Rosenberg, P., Zhou, Y., Kumar, A., Raymont, V., Ravert, H., Dannals, R., Nandi, A., Brasic, J., Ye, W.... (2010) In Vivo Imaging of Amyloid Deposition in Alzheimer Disease Using the Radioligand 18F-AV-45 (Flobetapir F 18). Journal of Nuclear Medicine, 51(6), 913-920. DOI: 10.2967/jnumed.109.069088
Clark, C., Schneider, J., Bedell, B., Beach, T., Bilker, W., Mintun, M., Pontecorvo, M., Hefti, F., Carpenter, A., Flitter, M.... (2011) Use of Florbetapir-PET for Imaging -Amyloid Pathology. JAMA: The Journal of the American Medical Association, 305(3), 275-283. DOI: 10.1001/jama.2010.2008
- January 17, 2011
- 01:51 AM
- 1,123 views
Of Boobs, Babes and the JAMA
by Pranab Chatterjee in Scepticemia
I have been an avid reader of the JAMA Online and especially been attracted to the cover art of every JAMA print issue. For those who do not know, the JAMA is the Journal of the American Medical Association and … Continue reading →... Read more »
Clark JP. (1999) Babes and boobs? analysis of JAMA cover art. BMJ (Clinical research ed.), 319(7225), 1603-4. PMID: 10600956
- January 10, 2011
- 10:55 AM
- 737 views
Rifaximin in IBS: A Quick Fix?
by Pranab Chatterjee in Scepticemia
This study published in the NEJM seems to have tackled the really dicey issue of unearthing a pharmacotherapeutic agent to deal with the rather ubiquitous, though poorly understood, and more often than not, even less poorly managed problem of irritable … Continue reading →... Read more »
Pimentel M, Lembo A, Chey WD, Zakko S, Ringel Y, Yu J, Mareya SM, Shaw AL, Bortey E, Forbes WP.... (2011) Rifaximin therapy for patients with irritable bowel syndrome without constipation. The New England journal of medicine, 364(1), 22-32. PMID: 21208106
- December 29, 2010
- 01:17 AM
- 1,548 views
The First Human RCT: Renal Sympathetic Denervation in Treatment Resistant Hypertension
by Pranab Chatterjee in Scepticemia
Treatment resistant hypertension has been an issue which has been bugging medical practitioners for a long time now. The first human trial on renal sympathetic denervation for treatment of this condition, the results of which have been recently published in … Continue reading →... Read more »
Symplicity HTN-2 Investigators. (2010) Renal sympathetic denervation in patients with treatment-resistant hypertension (The Symplicity HTN-2 Trial): a randomised controlled trial. The Lancet, 376(9756), 1903-1909. DOI: 10.1016/S0140-6736(10)62039-9
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