31 posts · 32,085 views
Musings of a Scepticemic Oslerphile.
A discussion of a peer reviewed publication in PLoS Medicine regarding the use of Prophylactic Adrenaline for prevention of Anti snake venom indiced anaphylaxis.... Read more »
de Silva, H., Pathmeswaran, A., Ranasinha, C., Jayamanne, S., Samarakoon, S., Hittharage, A., Kalupahana, R., Ratnatilaka, G., Uluwatthage, W., Aronson, J.... (2011) Low-Dose Adrenaline, Promethazine, and Hydrocortisone in the Prevention of Acute Adverse Reactions to Antivenom following Snakebite: A Randomised, Double-Blind, Placebo-Controlled Trial. PLoS Medicine, 8(5). DOI: 10.1371/journal.pmed.1000435
Once you have read the plot, you will understand what I am going to deal with in this post. The key to understanding how House reached a diagnosis of SSPE in the adopted kid was in a funny encounter he … Continue reading →... Read more »
McKee, M., & Diethelm, P. (2010) How the growth of denialism undermines public health. BMJ, 341(dec14 1). DOI: 10.1136/bmj.c6950
This is the first post in the new series on the blog where I analyze House MD episodes based on the content and scientific interpretation of the same. It is going to be a difficult ride trying to analyze a … Continue reading →... Read more »
Smith, K., Goy, E., Harvath, T., & Ganzini, L. (2011) Quality of Death and Dying in Patients who Request Physician-Assisted Death. Journal of Palliative Medicine, 14(4), 445-450. DOI: 10.1089/jpm.2010.0425
First up, a disclaimer. I know one of the researchers who conducted this short study personally and professionally. I admire their work and what they have done to further the cause of promoting research by medical students in India. So, … Continue reading →... Read more »
Sharma A, Dhanashree B. (2011) Screening of currency in circulation for bacterial contamination. . Current Science, 100(6), 822-825. info:other/
Playtime! Geriatric sexuality is a very sparsely explored domain in the medical arena. With the developing world getting top heavy on the age pyramid, this has become a rather timely question to ask. This study conducted in Australia takes a … Continue reading →... Read more »
Hyde Z, Flicker L, Hankey GJ, Almeida OP, McCaul KA, Chubb SA, & Yeap BB. (2010) Prevalence of sexual activity and associated factors in men aged 75 to 95 years: a cohort study. Annals of internal medicine, 153(11), 693-702. PMID: 21135292
How many of us have been reduced to blubbering idiots by the tears of a distressed damsel? I am sure the casualties are too many to put a number. Almost all of us have come across a time when we … Continue reading →... Read more »
Frederick Chopin is not only one of the greatest composers this side of history, but also, a paleopathologist’s delight. He died at the age of 39, which, even by the standards of those days, was quite young. There were several … Continue reading →... Read more »
The FDA has conditionally approved the novel contrast agent, Florbetapir, to help in the diagnosis of amyloid beta plaque build up in the brains of Alzheimer’s (or, for that purpose, any damn dementia) patients. Now there are several reasons why … Continue reading →... Read more »
Wong, D., Rosenberg, P., Zhou, Y., Kumar, A., Raymont, V., Ravert, H., Dannals, R., Nandi, A., Brasic, J., Ye, W.... (2010) In Vivo Imaging of Amyloid Deposition in Alzheimer Disease Using the Radioligand 18F-AV-45 (Flobetapir F 18). Journal of Nuclear Medicine, 51(6), 913-920. DOI: 10.2967/jnumed.109.069088
Clark, C., Schneider, J., Bedell, B., Beach, T., Bilker, W., Mintun, M., Pontecorvo, M., Hefti, F., Carpenter, A., Flitter, M.... (2011) Use of Florbetapir-PET for Imaging -Amyloid Pathology. JAMA: The Journal of the American Medical Association, 305(3), 275-283. DOI: 10.1001/jama.2010.2008
I have been an avid reader of the JAMA Online and especially been attracted to the cover art of every JAMA print issue. For those who do not know, the JAMA is the Journal of the American Medical Association and … Continue reading →... Read more »
This study published in the NEJM seems to have tackled the really dicey issue of unearthing a pharmacotherapeutic agent to deal with the rather ubiquitous, though poorly understood, and more often than not, even less poorly managed problem of irritable … Continue reading →... Read more »
Pimentel M, Lembo A, Chey WD, Zakko S, Ringel Y, Yu J, Mareya SM, Shaw AL, Bortey E, Forbes WP.... (2011) Rifaximin therapy for patients with irritable bowel syndrome without constipation. The New England journal of medicine, 364(1), 22-32. PMID: 21208106
Treatment resistant hypertension has been an issue which has been bugging medical practitioners for a long time now. The first human trial on renal sympathetic denervation for treatment of this condition, the results of which have been recently published in … Continue reading →... Read more »
Symplicity HTN-2 Investigators. (2010) Renal sympathetic denervation in patients with treatment-resistant hypertension (The Symplicity HTN-2 Trial): a randomised controlled trial. The Lancet, 376(9756), 1903-1909. DOI: 10.1016/S0140-6736(10)62039-9
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