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Discussions on the interface between Science and Society, Politics, Religion, Life, and whatever else I decide to write about.
An older study brought to my attention recently (subscription required, though I also found this link).
This is strictly to avoid a dong
being the lead in picture on FoS
The authors want to test some ideas regarding behaviors and adaptations human males may have to ensure paternity. As I heard about this research, my skeptic meter went off and I whipped out my critical thinking tool box to look at this problem and research more closely. The colleague telling me about this research see........ Read more »
This weeks journal club was on Cryptococcus neoformans and an odd way it may get of out macrophage some of the time, at least in vitro, maybe. The paper in question is:
The Human Fungal Pathogen Cryptococcus neoformans Escapes Macrophages by a Phagosome Emptying Mechanism That Is Inhibited by Arp2/3 Complex-Mediated Actin Polymerisation by Simon A. Johnston, Robin C. May. PLoS Pathogens 6(8) e1001041.
This work follows up a really cool observation published by t........ Read more »
Johnston SA, & May RC. (2010) The human fungal pathogen Cryptococcus neoformans escapes macrophages by a phagosome emptying mechanism that is inhibited by Arp2/3 complex-mediated actin polymerisation. PLoS pathogens, 6(8). PMID: 20714349
We started our Microbiology Journal Club of the new year, technically a new decade. We started off with a bang, well a bang from a physics perspective, more of a whimper from a microbiology perspective.
The paper under discussion was:
Helicobacter pylori moves through mucus by reducing mucin viscoelasticity. by Celli JP et al. Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14321-6.
The basic premise is that H. pylori, a spiral shaped bacteria is thought to burrow its wa........ Read more »
Celli, J., Turner, B., Afdhal, N., Keates, S., Ghiran, I., Kelly, C., Ewoldt, R., McKinley, G., So, P., Erramilli, S.... (2009) Helicobacter pylori moves through mucus by reducing mucin viscoelasticity. Proceedings of the National Academy of Sciences, 106(34), 14321-14326. DOI: 10.1073/pnas.0903438106
By now many have heard about the recent study published in Pediatrics which, of course, shows a clear link between extensive video game playing and depression in teenagers. You may have also heard about another recent publication of a study conducted by 8-10 year olds.
"How are these studies related?" You may ask.
"They are not." I may respond. Actually I will respond. These studies have nothing to do with each other. However, they are related from the perspective that they are BIG news!
In t........ Read more »
Gentile DA, Choo H, Liau A, Sim T, Li D, Fung D, & Khoo A. (2011) Pathological Video Game Use Among Youths: A Two-Year Longitudinal Study. Pediatrics. PMID: 21242221
Plasmodium falciparum is the leading cause of malaria in people, although there are Plasmodium species, spp., that infect virtually all the tetrapods (mammals, birds, reptiles, amphibians). As most people know, malaria is acquired from mosquito bites (Anopheles mosquitoes to be specific), because Plasmodium spp. have complex life cycles that require both an insect (mosquito) and a tetrapod host. Importantly, there is essentially no overlap between the Plasmodium spp. that cause fr........ Read more »
Joergensen, L., Bengtsson, D., Bengtsson, A., Ronander, E., Berger, S., Turner, L., Dalgaard, M., Cham, G., Victor, M., Lavstsen, T.... (2010) Surface Co-Expression of Two Different PfEMP1 Antigens on Single Plasmodium falciparum-Infected Erythrocytes Facilitates Binding to ICAM1 and PECAM1. PLoS Pathogens, 6(9). DOI: 10.1371/journal.ppat.1001083
A honeybee colony. Photograph: Haraz N Ghanbari/AP
from The Guardian
I have already expounded on the awesome power of fungi against mammals (bats), amphibians (frogs), and nematodes (worm), now it is time for the insects to go down...well, maybe. Over the last five or so years, honeybee colonies have been dying off at a dramatic rate, this is referred to as colony collapse disorder (CCD). Basically the bees in a colony go all Roanoke and it is unclear why.
Several studies of CCD have re........ Read more »
Bromenshenk, J., Henderson, C., Wick, C., Stanford, M., Zulich, A., Jabbour, R., Deshpande, S., McCubbin, P., Seccomb, R., Welch, P.... (2010) Iridovirus and Microsporidian Linked to Honey Bee Colony Decline. PLoS ONE, 5(10). DOI: 10.1371/journal.pone.0013181
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