I know that I'm probably starting to sound like a broken record on the topic of wandering (elopement) and autism on this blog (see here and see here and see here) but I am yet again going to briefly talk about peer-reviewed research in this area simply because it's just too damned important not to.This time around the results from Catherine Rice and colleagues  are the source of my musings and the conclusion that: "wandering among children with ASD [autism spectrum disorder], regardless of intellectual disability status, is relatively common." Based on the analysis of data from The Survey of Pathways to Diagnosis and Services (SPDS) initiative, where specific questions about 'wandering and wandering prevention' are asked (see page 29) researchers reported that: "For children with special healthcare needs diagnosed with either ASD, intellectual disability, or both, wandering or becoming lost during the previous year was reported for more than 1 in 4 children." A diagnosis of ASD seemed to be a key factor in the frequency of wandering, where those with additional learning disability were the most likely to wander (37% of the sample) and figures for those without intellectual disability came in at about 32%.As per previous occasions when I've blogged about this topic, the differences (kingdoms) that might divide various groups/people when it comes to autism tend to take second place when it comes to tackling this issue and preventing (yes, preventing) wandering from turning into something rather more ominous. After all, there are a range of measures that can be employed to reduce the frequency of wandering/elopement and, if and when it does happen, reduce the probability of 'adverse outcomes' for the wanderer. First and foremost I would say, is for more people to take note of actual accounts about wandering as per those discussed by Solomon and Lawlor  for example. One can learn a lot about the circumstances around why wandering occurs and the different types of wandering (including the issue of bolting) from listening to parent and caregiver accounts. They are the experts on their own children and no doubt some of those accounts might generalise to more than just one child.Next up are the various instruments that could be used to help find wanderers in a timely fashion. I'm thinking specifically about technology such as GPS trackers and the need for science to provide some further insight into the effectiveness of such items and what needs to be done to improve their effectiveness. I appreciate that 'tracking people' might have implications for things like civil liberties but just remember that the mobile (cell) phone you're carrying might not also be bad at telling others where you are. Improving autism awareness among first responders such as police and related agencies may also help them in their efforts if and when wandering becomes an issue.Finally and bearing in mind that 'if you've met one person with autism, you've met one autistic person' (or words to that effect) is the importance of teaching things like road and water safety to those on the autism spectrum. I appreciate that the concept of 'danger' might not be something easily taught to some children and communication issues can be barriers to effective teaching. But, one should not assume that it is impossible to do , alongside the strategies for making lessons like swimming classes for example 'fun' as well as potentially lifesaving. And yes, swimming lessons can be particularly fun for many children on the autism spectrum .---------- Rice CE. et al. Reported Wandering Behavior among Children with Autism Spectrum Disorder and/or Intellectual Disability. J Pediatr. 2016 May 2. pii: S0022-3476(16)00428-5. Call NA. et al. Clinical outcomes of behavioral treatments for elopement in individuals with autism spectrum disorder and other developmental disabilities. Autism. 2016 May 12. pii: 1362361316644732. Eversole M. et al. Leisure Activity Enjoyment of Children with Autism Spectrum Disorders. J Autism Dev Disord. 2016 Jan;46(1):10-20.----------Rice, C., Zablotsky, B., Avila, R., Colpe, L., Schieve, L., Pringle, B., & Blumberg, S. (2016). Reported Wandering Behavior among Children with Autism Spectrum Disorder and/or Intellectual Disability The Journal of Pediatrics DOI: 10.1016/j.jpeds.2016.03.047... Read more »
Rice, C., Zablotsky, B., Avila, R., Colpe, L., Schieve, L., Pringle, B., & Blumberg, S. (2016) Reported Wandering Behavior among Children with Autism Spectrum Disorder and/or Intellectual Disability. The Journal of Pediatrics. DOI: 10.1016/j.jpeds.2016.03.047
I discuss how global warming may affect the reproductive success of male lions.... Read more »
West PM, & Packer C. (2002) Sexual selection, temperature, and the lion's mane. Science (New York, N.Y.), 297(5585), 1339-43. PMID: 12193785
by Piter Kehoma Boll Males and females are defined by their gametes. Males have tiny, usually mobile gametes, while females have very large gametes that usually do not move. This means that females produce less gametes, but put a lot … Continue reading →... Read more »
Córdoba-Aguilar, A., Vrech, D., Rivas, M., Nava-Bolaños, A., González-Tokman, D., & González-Soriano, E. (2014) Allometry of Male Grasping Apparatus in Odonates Does Not Suggest Physical Coercion of Females. Journal of Insect Behavior, 28(1), 15-25. DOI: 10.1007/s10905-014-9477-x
Did you know that there may be bits of your own body that you don't own? That may be owned by someone else? No?? Then you need to know more about Gene Patenting...... Read more »
Rosenfeld, J., & Mason, C. (2013) Pervasive sequence patents cover the entire human genome. Genome Medicine, 5(3), 27. DOI: 10.1186/gm431
Liddicoat J, Whitton T, & Nicol D. (2015) Are the gene-patent storm clouds dissipating? A global snapshot. Nature biotechnology, 33(4), 347-52. PMID: 25850055
AG McCluskey. (2016) Patent-ly Obvious..?. Zongo's Cancer Diaries. info:/
Like it or not: Our discipline is very much dominated by positivism and the application of the scientific method, which assumes that new knowledge can be created by developing and testing theory or, in other words, by induction or deduction. Another type of inference is abduction. Spens & Kovács (2006) present an overview of the […]... Read more »
Spens, K., & Kovács, G. (2006) A Content Analysis of Research Approaches in Logistics Research. International Journal of Physical Distribution , 36(5), 374-390. DOI: 10.1108/09600030610676259
If you feel brave enough, today I will direct your reading attention to the paper by Michael Williams and colleagues  detailing the application of a particularly important genome editing technique called CRISPR-Cas9  to autism-related science.Titled: "A Retroviral CRISPR-Cas9 System for Cellular Autism-Associated Phenotype Discovery in Developing Neurons" the Williams paper probably won't win any awards for plain English but don't be fooled about just how important this paper might be in the grand era of 'we can edit genomes' and how this might translate into modelling particular types of autism or genetic issues linked to autism in mice or other animals for example.I really wish that I could say I was an expert on CRISPR-Cas9 and understood every detail included in the Williams paper but alas, I'm not and I didn't. Bearing in mind my non-expertise ('a cobbler should stick to his last') I did want to include it on this blog given the excitement in this area. Take my observations however, with a large pinch of salt...So a definition of CRISPR [clustered regularly interspaced short palindromic repeats] -Cas9 - well, I don't want to reinvent the wheel so I'll use that offered in reference  with full credit given to the writer (Steph Yin): "Here’s how CRISPR/Cas works in bacteria: When bacteria encounter an invading source of DNA, such as from a virus, they can copy and incorporate segments of the foreign DNA into their genome as “spacers” between the short DNA repeats in CRISPR. These spacers enhance the bacteria’s immune response by providing a template for RNA molecules to quickly identify and target the same DNA sequence in the event of future viral infections. If the RNA molecules recognize an incoming sequence of foreign DNA, they guide the CRISPR complex to that sequence. There, the bacteria’s Cas proteins, which are specialized for cutting DNA, splice and disable the invading gene." The application of this process outside of just bacteria was subsequently recognised and a 'gene editing tool' was eventually born whereby a CRISPR-Cas9 system could replace any gene sequence.Clear as mud right?Well, Williams et al add to a small but emerging peer-reviewed research base at the time of writing suggesting that CRISPR-Cas9 might provide some important insights into at least 'some' autism. Their particular idea was to "mimic nonsense PTEN mutations from autism patients in developing mouse neurons" on the back of some previous research suggesting that various genetic issues with PTEN might be present in some autism . Nonsense mutation by the way, normally ends in 'nonfunctional proteins' based on the knowledge that [some] genes provide the template to make proteins.To achieve such mutations in PTEN authors used "retroviral implementation of the CRISPR-Cas9 system" where engineered retroviruses were purposed to deliver something mimicking a genetic mutation previously noted in cases of autism that were then injected into "the hippocampus of postnatal day 7 (P7) mice." Researchers then monitored the retrovirus infected cells to see what they looked like in terms of carrying the mutation and hence showing loss of PTEN function or not. They noted that there was a degree of 'hit-and-miss' based on their approach but were "able to clearly discern the established hypertrophic phenotype due to loss of Pten function across the cell population on average."Not content with such molecular engineering, authors also turned their attention to designing viruses "to target a gene that has recently been associated with autism, KATNAL2." KATNAL2 has been described by other authors as a 'genuine' autism risk factor  (er, right...) and on that basis researchers designed a retrovirus carrying a mutation designed to disrupt expression of the gene. After some preliminary work to test out how successful their retrovirus delivered mutation was in the test tube, they injected it and/or a control retrovirus into the brain of another set of mice. They found some interesting changes in the experimental retrovirus-infected brains pertinent to "decreased dendritic arborization of developing neurons." In layman's terms this equates as evidence of "disruption of normal neuronal development" that "may lead to synaptic circuit dysfunction underlying the autism phenotype."As per my earlier 'pinch of salt' sentiments I am not offering any authoritative opinion about the Williams paper and the techniques included. My interpretation is just that; interested readers are advised to do a little more reading around this subject before quoting my text as 'truth'. What I do hope that I've got across is the message that CRISPR-Cas9 and the delivery of engineered genetic mutations via something like a retrovirus is already here and will no doubt be impacting on autism research in times to come. In an era where 'the autism gene' has been replaced by a more general model of many different genes potentially producing many different autisms (see here), one can perhaps see how focusing in on specific genes linked to 'some' autism might be ripe for this kind of analysis (see here). I say all that recognising that whilst many would love to be able to say that autism is solely a genetic condition, the role of non-genetic factors variably affecting risk is not to be forgotten (see here).We will see what else emerges in the peer-reviewed domain in this brave new world...---------- Williams MR. et al. A Retroviral CRISPR-Cas9 System for Cellular Autism-Associated Phenotype Discovery in Developing Neurons. Sci Rep. 2016 May 10;6:25611. Yin S. What Is CRISPR/Cas9 and Why Is It Suddenly Everywhere? Motherboard. 2015. April 30. Neale BM. et al. Patterns and rates of exonic de novo mutations in autism spectrum disorders. Nature. 2012 Apr 4;485(7397):242-5.----------Williams MR, Fricano-Kugler CJ, Getz SA, Skelton PD, Lee J, Rizzuto CP, Geller JS, Li M, & Luikart BW (2016). A Retroviral CRISPR-Cas9 System for Cellular Autism-Associated Phenotype Discovery in Developing Neurons. Scientific reports, 6 PMID: 27161796... Read more »
Williams MR, Fricano-Kugler CJ, Getz SA, Skelton PD, Lee J, Rizzuto CP, Geller JS, Li M, & Luikart BW. (2016) A Retroviral CRISPR-Cas9 System for Cellular Autism-Associated Phenotype Discovery in Developing Neurons. Scientific reports, 25611. PMID: 27161796
Feelings of shame and humiliation bother obese air passengers more than tight seat belts and tiny seats, according to a study published by Ben-Gurion University of the Negev (BGU) researchers. Participants interviewed for the study recounted the typical challenges they encounter while boarding, in-flight and deplaning.
... Read more »
Yaniv Poria, & Jeremy Beal. (2016) An Exploratory Study about Obese People’s Flight Experience . Journal of travel research. info:/10.1177/0047287516643416
The most comprehensive index of open access journals, the Directory of Open Access Journals (DOAJ), reviewed its inclusion criteria, in view of allegations of the presence of predatory journals. This restructuring will lead to more than 3,000 journals to be removed from the database. DOAJ, besides advocating Open Access, established, in collaboration with COPE, OASPA and WAME, a code of principles and good practices in scientific publishing. … Read More →... Read more »
There are many risk factors for Alzheimer's Disease (AD) including history of head trauma and family history of AD.The strongest risk factor is advanced age. Yearly risk for AD is about 1% per year in 70 year old populations jumping to around 7% in 90 year old groups.Now a recent study is shedding some light on a new risk for AD in men. This risk appears to be related to a chromosome Y phenomenon known to be associated with aging.Elderly men show a tendency to lose the Y chromosome from a small percentage of cells over time. This phenomenon is known as loss of Y or LOY.The percentage of blood cells with LOY can be determined. A study recently published in Journal of Human Genetics (see citation below) found significant support for higher percentage of LOY being linked to AD risk.Here are the key findings:In a sample of 3218 elderly men 17% showed evidence of LOY chromosome mosaicismLOY percentage rates were strongly positively correlated with older ageMen with AD had higher rates of LOY than age-matched men without AD (adjusted odds ratio=2.80)Two prospective studies found higher rates of incident AD in men with LOY (adjusted odds ratio=6.80)These findings are not simply minor as the effect of LOY on risk appears similar in magnitude to the strongest genetic risk factor for AD, APOE gene status.LOY has also been linked to a higher risk of cancer, so it appears to be a non-specific risk factor.The authors of this study note;"Regardless of the underlying mechanism(s) for the increased risk of AD and cancer in men with LOY in blood, our and other's published results reinforce a role of factors on chromosome Y in various, still poorly explored biological processes, other than sex determination and sperm production."LOY is not yet a common test in clinical practice. However, I think we will be hearing much more on this association with potential for screening and intervention studies.Access the free full-text manuscript by clicking on the DOI link in the citation below.Follow me on Twitter WRY999Photo of eastern screech owl is from my photo files.d sperm production.Dumanski JP et al (2016). Mosiac loss of chromosome Y in blood is associated with Alzheimer's disease American Journal of Human Genetics : 10.1016/j.ajhg.2016.05.014... Read more »
Dumanski JP et al. (2016) Mosiac loss of chromosome Y in blood is associated with Alzheimer's disease. American Journal of Human Genetics. info:/10.1016/j.ajhg.2016.05.014
The fight against aging Ever since the ancient Sumerians, men has sought eternal life. We still do. Anti-aging science has become quite an industry. As we dive deeper and deeper into our biological foundations, we’re learning more and more about how and why we age. A lot of mysteries remain, but there’s still talk about […]... Read more »
There are many tools at NCBI, with a huge range of functions. Literature, sequence data, variations, protein structure, chemicals and bioassays, and more. It’s hard to keep track of what’s available. Their video tutorials are helping me to be aware of new tools, and new features within existing tools. For this week’s Tip of the […]... Read more »
Kapustin, Y., Souvorov, A., Tatusova, T., & Lipman, D. (2008) Splign: algorithms for computing spliced alignments with identification of paralogs. Biology Direct, 3(1), 20. DOI: 10.1186/1745-6150-3-20
NCBI staff. (2016) Database resources of the National Center for Biotechnology Information. Nucleic Acids Research, 44(D1). DOI: 10.1093/nar/gkv1290
Just like some people have a tendency to go overboard, so do some immune systems. Here’s all the ways that your immune system can get it wrong and leave you with allergies – and how some allergies can save your life.... Read more »
Calboli FC, Cox DG, Buring JE, Gaziano JM, Ma J, Stampfer M, Willett WC, Tworoger SS, Hunter DJ, Camargo CA Jr, Michaud DS. (2011) Prediagnostic plasma IgE levels and risk of adult glioma in four prospective cohort studies. J Natl Cancer Inst. . DOI: 10.1093/jnci/djr361
Joseph A Jackson, Ida M Friberg, Luke Bolch, Ann Lowe, Catriona Ralli, Philip D Harris, Jerzy M Behnke, Janette E Bradley. (2009) Immunomodulatory parasites and toll-like receptor-mediated tumour necrosis factor alpha responsiveness in wild mammals. BMC Biology. DOI: 10.1186/1741-7007-7-16
According to the philosophy of "lean space management", a minimalist workspace shorn of clutter is distraction-free and ideal for productivity. But this philosophy turns out to have slim empirical foundations, and as promoting a sense of identity at work, including personalising the work space, generally leads to better outcomes, there’s reason to expect richer, characterful workplaces to be more beneficial. A new article in the Journal of Personnel Psychology builds on this past work, showing that rich and meaningful workplace decor produces better team performance than lean spaces, even in surprising contexts.Katherine Greenaway and her colleagues asked 54 students (45 women) to form teams of three or four members. The researchers then explained to each team that there were Red teams and Blue teams and that theirs was a Red team. This was a ruse because in reality all teams were told that theirs was a Red team. To stoke a sense of competition, the researchers added that the participants' team performance and that of other Red teams would be compared against the rival Blue teams. The participants then had a chance to get to know their team-mates and to personalise their own team room with a poster that they made together and with red decorations.But the teams couldn’t enjoy this for long, as a contrived double booking meant they were cast out from their room into a new work environment that they were told had recently housed another team. Some teams were rehoused in a lean, undecorated room; others in a room that had clearly been used by a Red team; and the remainder in a room that was dressed up as Blue territory.In this new environment, the teams had to complete a task: finding words in a grid, and then using them to construct sentences. The researchers found that teams moved to a friendly Red room or an unfriendly Blue room performed better than those placed in a lean room.Remember, the decorations were based on the arbitrary, colour-themed team allocation process, so their specifics couldn’t have been profoundly inspiring. Nor could they represent a shared and personal endeavour: in all cases, the teams’ own poster that they made and their decorative decisions were out of sight in another room.In the case of those teams rehoused in a different Red room, some insight into their better performance comes from an attitude survey the participants took after the word task. They tended to give higher ratings to items like “I identify with the group that was in this room before us”. It seems the room triggered or sustained a general feeling of “Reds together” and the data suggested this identification drove their better performance.What about the finding of superior team performance in a Blue-room? The researchers had predicted that being in enemy territory might spark competitive feelings that would boost performance, at least in the short-term. The teams placed in a Blue room did indeed feel more competitive but there was no sign in the data that this was linked with superior performance, so there’s still a question mark over this part of the study.All in all, the research suggests that workspaces with a rich character are more supportive of team performance than those built for anonymity. As the authors conclude: meaning beats leaning._________________________________ Greenaway, K., Thai, H., Haslam, S., & Murphy, S. (2016). Spaces That Signal Identity Improve Workplace Productivity Journal of Personnel Psychology, 15 (1), 35-43 DOI: 10.1027/1866-5888/a000148 --further reading--Why it's important that employers let staff personalise their workspacesPost written by Alex Fradera (@alexfradera) for the BPS Research Digest.Our free weekly email will keep you up-to-date with all the psychology research we digest: Sign up!
... Read more »
Greenaway, K., Thai, H., Haslam, S., & Murphy, S. (2016) Spaces That Signal Identity Improve Workplace Productivity. Journal of Personnel Psychology, 15(1), 35-43. DOI: 10.1027/1866-5888/a000148
Knee flexion to 90 degrees limits ankle laxity with the talar tilt test in comparison to a fully extended knee. However, knee position has no effect on anterior drawer laxity. Muscle guarding will limit our ability to accurately assess ankle laxity with a talar tilt or anterior drawer test. ... Read more »
Hanlon S, Caccese J, Knight CA, Swanik CB, & Kaminski TW. (2016) Examining Ankle-Joint Laxity Using 2 Knee Positions and With Simulated Muscle Guarding. Journal of Athletic Training, 51(2), 111-7. PMID: 26881870
Some behaviours associated with a diagnosis of autism don't make for great dinner table discussion. Self-injurious behaviours (SIBs), as exemplified by head banging, hair pulling and eye gouging must rank as some of the more distressing facets of [some] autism insofar as their potential effect on the person and also the people around them.These and other types of behaviour commonly headed under the category of so-called 'challenging behaviours' have tended not to be too evident when it comes to the public depiction of autism it has to be said. I can appreciate why, but what this can mean is that such issues tend to get 'brushed under the carpet'. In recent times however, there does seem to be a greater willingness for research to delve into such behaviours .The paper by Caroline Richards and colleagues  (open-access) looking at the persistence of such behaviour(s) and the potential correlates associated with their persistence is a welcome piece of research added to the research interest. Highlighting how for a small research sample of 67 children/young adults with autism over three-quarters reported SIB persisting over a 3-year period, the data provide some interesting insights into the nature of this issue and, potentially how it should be screened for and managed.Based here in Blighty, researchers initially managed to recruit 190 participants, the data for some of whom were previously published . As perhaps one might expect, the follow-up after on average 36.4 months had elapsed was not so well-populated. No mind, various findings are reported including that "the presence, topography and severity of self-injury were persistent and stable over three years" and that "individuals with self-injury were significantly more likely to be non-verbal than those who did not engage in self-injury." Further: "individuals with self-injury were significantly more likely to be less able and non-verbal and to show higher levels of stereotyped behaviour, compulsive behaviour, insistence on sameness, overactivity, impulsivity, repetitive behaviour and impairments in social interaction."There is quite a bit more to do on this topic including facing up to issues around the small (eventual) participant size and the reliance on 'a questionnaire pack' as the chosen method of assessment. The authors also talk quite a bit about how some of the behaviours observed in connection with self-injury - impaired behavioural inhibition - might overlap with other diagnoses such as attention-deficit hyperactivity disorder (ADHD) but as far as I can see, they did not directly screen for ADHD outside of the use of something called The Activity Questionnaire (TAQ). I might also have liked to have seen a little more information about how parents/professionals had 'tackled' SIB in this cohort and what effect that might have had on results. Investigations remain.Having said all that, the insights provided by the Richards article are important and provide plenty of food for thought when it comes to SIB and autism. Without trying to generalise SIB to all autism nor to come across as portraying too negative an image of what autism can mean to someone, recognition and management (dare I say treatment) of such behaviours when present should really be a priority .----------- Maddox BB. et al. Untended wounds: Non-suicidal self-injury in adults with autism spectrum disorder. Autism. 2016 May 12. pii: 1362361316644731. Richards C. et al. Persistence of self-injurious behaviour in autism spectrum disorder over 3 years: a prospective cohort study of risk markers. Journal of Neurodevelopmental Disorders 2016; 8: 21. Richards C. et al. Self-injurious behaviour in individuals with autism spectrum disorder and intellectual disability. J Intellect Disabil Res. 2012 May;56(5):476-89. Lee Y-H. et al. Cataract secondary to self-inflicted blunt trauma in children with autism spectrum disorder. Journal of American Association for Pediatric Ophthalmology and Strabismus. 2016. May 17.----------Richards, C., Moss, J., Nelson, L., & Oliver, C. (2016). Persistence of self-injurious behaviour in autism spectrum disorder over 3 years: a prospective cohort study of risk markers Journal of Neurodevelopmental Disorders, 8 (1) DOI: 10.1186/s11689-016-9153-x... Read more »
Richards, C., Moss, J., Nelson, L., & Oliver, C. (2016) Persistence of self-injurious behaviour in autism spectrum disorder over 3 years: a prospective cohort study of risk markers. Journal of Neurodevelopmental Disorders, 8(1). DOI: 10.1186/s11689-016-9153-x
In their book The Parasite-Stress Theory of Values and Sociality, Randy Thornhill, Distinguished Professor at The University of New Mexico, and Corey L. Fincher, Assistant Professor at University of Warwick, present a new interpretation of human values and cultural behaviors, on the basis of ecological variations in parasite-stress prevalence across and within nations. Before delineating […]... Read more »
Pazhoohi, F. (2016) The Parasite-Stress Theory of Values and Sociality, Infectious Disease, History and Human Values Worldwide (Book Review). Canadian Studies in Population, 43(1-2), 155-157. info:/
Smashing out of its egg is only the first step in a baby sea turtle's grueling early days. The turtle fights free of its eggshell only to find itself buried underground. It has to intuit which way is up, then dig out of the packed sand. As soon as it breaks onto the surface of the beach, it begins a mad sprint to the ocean. All around are its brothers and sisters, flailing toward the water as fast as their own flippers will carry them. In the sea they'll keep swimming frantically, trying to ... Read more »
Rusli, M., Booth, D., & Joseph, J. (2016) Synchronous activity lowers the energetic cost of nest escape for sea turtle hatchlings. The Journal of Experimental Biology, 219(10), 1505-1513. DOI: 10.1242/jeb.134742
The Directory of Open Access Journals bans dubious journals from its index.... Read more »
Almost five years ago, we wrote about research saying men with deep voices were more persuasive. Science has moved forward though and now, women can also be more persuasive when using a deeper voice. Some call it a “sultry voice”. New work tells us your voice doesn’t have be a deep and resonant baritone to […]
Who has the deepest voice amongst the Republican candidates for President?
Feel the power of that deep and resonant voice!
Here’s why that movie wasn’t called ’12 Angry Women’
... Read more »
Cheng JT, Tracy JL, Ho S, & Henrich J. (2016) Listen, follow me: Dynamic vocal signals of dominance predict emergent social rank in humans. Journal of Experimental Psychology, General, 145(5), 536-47. PMID: 27019023
Psychological science is surprisingly difficult to replicate (Open Science Collaboration, 2015). Researchers are desperate to find out why. A new study in the prestigious journal PNAS (Van Bavel et al., 2016) claims unknown contextual factors of psychological phenomena (“hidden moderators”) are to blame. The more an effect is sensitive to unknown contextual factors, the less […]... Read more »
Dreber, A., Pfeiffer, T., Almenberg, J., Isaksson, S., Wilson, B., Chen, Y., Nosek, B., & Johannesson, M. (2015) Using prediction markets to estimate the reproducibility of scientific research. Proceedings of the National Academy of Sciences, 112(50), 15343-15347. DOI: 10.1073/pnas.1516179112
Kunert, R. (2016) Internal conceptual replications do not increase independent replication success. Psychonomic Bulletin . DOI: 10.3758/s13423-016-1030-9
Open Science Collaboration. (2015) Estimating the reproducibility of psychological science. Science, 349(6251). DOI: 10.1126/science.aac4716
Van Bavel, J.J., Mende-Siedlecki, P., Brady, W.J., & Reinero, D.A. (2016) Contextual sensitivity in scientific reproducibility. PNAS. info:/
Do you write about peer-reviewed research in your blog? Use ResearchBlogging.org to make it easy for your readers — and others from around the world — to find your serious posts about academic research.
If you don't have a blog, you can still use our site to learn about fascinating developments in cutting-edge research from around the world.
Research Blogging is powered by SMG Technology.
To learn more, visit seedmediagroup.com.