Post List

  • September 9, 2014
  • 06:03 AM
  • 65 views

Punning with the Pub in PubMed: Are there any decent NCBI puns left? #PubMedPuns

by Duncan Hull in O'Really?

Many people claim they get all their best ideas in the Pub, but for lots of scientists their best ideas probably come from PubMed.gov – the NCBI’s monster database of biomedical literature. Consequently, the database has spawned a whole slew of tools that riff off the PubMed name, many puns and portmanteaus (aka “PubManteaus”), the pub-based wordplays are very common. All of this might make you wonder, are there any decent PubMed puns left? Here’s an incomplete coll........ Read more »

Gibney Elizabeth. (2014) How to tame the flood of literature. Nature, 513(7516). PMID: 25186906  

Kumar Neeraj, Berg Alexander, Belhumeur Peter N, & Nayar Shree. (2011) Describable Visual Attributes for Face Verification and Image Search. IEEE transactions on pattern analysis and machine intelligence. PMID: 21383395  

McEntyre Johanna R, Ananiadou Sophia, Andrews Stephen, Black William J, Boulderstone Richard, Buttery Paula, Chaplin David, Chevuru Sandeepreddy, Cobley Norman, & Coleman Lee-Ann. (2010) UKPMC: a full text article resource for the life sciences. Nucleic acids research. PMID: 21062818  

  • September 9, 2014
  • 04:35 AM
  • 72 views

The gondii and generalised anxiety disorder

by Paul Whiteley in Questioning Answers

Toxoplasma gondii (T. gondii) has been absent from discussions on this blog for a while now. I'm going to remedy that today with this post talking about the paper from Markovitz and colleagues [1] who concluded: "T. gondii infection may play a role in the development of GAD [generalized anxiety disorder]"."You have saved our lives. We are eternally grateful"Based on participants taking part in the Detroit Neighborhood Health Study exposure to T. gondii "defined by seropositivity a........ Read more »

Markovitz A, Simanek AM, Yolken R, Galea S, Koenen KC, Chen S, & Aiello AE. (2014) Toxoplasma gondii and anxiety disorders in a community-based sample. Brain, behavior, and immunity. PMID: 25124709  

  • September 8, 2014
  • 09:05 PM
  • 81 views

The atmosphere and what we eat: significant increases in greenhouse gas emissions predicted for high-calorie diets recommended by USDA

by Jonathan Trinastic in Goodnight Earth

New research shows that shifting to recommended, high-calorie USDA diets could increase GHG emissions due to the dairy required to make up for reduced meat/poultry calories. What we eat impacts our long-term environment!... Read more »

  • September 8, 2014
  • 06:07 PM
  • 70 views

Genes Smash! An Oxytricha trifallax story

by Gabriel in Lunatic Laboratories

In DNA mutation is often a bad thing. It’s sort of like building a car, there are far more wrong ways to one together than there are right ways. Still, mutation happens often which brings with it good (and more often bad) things. Usually mutation is spontaneous, it has no real rhyme or reason (in a broad sense) and while it brings things like cancers, it also can bring amazingly beneficial traits too.... Read more »

Chen X, Bracht JR, Goldman AD, Dolzhenko E, Clay DM, Swart EC, Perlman DH, Doak TG, Stuart A, Amemiya CT.... (2014) The Architecture of a Scrambled Genome Reveals Massive Levels of Genomic Rearrangement during Development. Cell, 158(5), 1187-98. PMID: 25171416  

  • September 8, 2014
  • 04:40 PM
  • 71 views

“If I do that, I’ll be in more pain and won’t sleep and …” Tampa Scale of Kinesiophobia reformulated

by Bronwyn Thompson in Healthskills: Skills for Healthy Living

The TSK has been used for many years now as a good measure of kinesiophobia. Usually scores of above 45 (from a possible 68) suggest that the person has beliefs that their pain represents ongoing damage (Somatic focus) and that they should avoid doing anything that provokes pain (Activity avoidance). High scores have been associated with a wide range of negative outcomes including pain intensity, disability, distress – and in a wide range of individuals including people with chronic low b........ Read more »

  • September 8, 2014
  • 04:06 PM
  • 60 views

Measles Virus: a lot of autophagy

by thelonevirologist in Virology Tidbits

Measles is a highly contagious disease cause by the infection with Measles Virus (MeV), a Morbillivirus belong to the order of the Paramyxoviridae, of the respiratory tract characterised by a distinctive maculapapular rash and fever among other symptoms, causing also severe complications such as post-infectious encephalitis. MeV is a negative strand (non-segmented) enveloped RNA virus encoding for six structural and two non-structural proteins. So far three host cell receptors for MeV have been ........ Read more »

Ader N, Brindley M, Avila M, Örvell C, Horvat B, Hiltensperger G, Schneider-Schaulies J, Vandevelde M, Zurbriggen A, Plemper RK.... (2013) Mechanism for active membrane fusion triggering by morbillivirus attachment protein. Journal of virology, 87(1), 314-26. PMID: 23077316  

Joubert PE, Meiffren G, Grégoire IP, Pontini G, Richetta C, Flacher M, Azocar O, Vidalain PO, Vidal M, Lotteau V.... (2009) Autophagy induction by the pathogen receptor CD46. Cell host , 6(4), 354-66. PMID: 19837375  

Grégoire IP, Richetta C, Meyniel-Schicklin L, Borel S, Pradezynski F, Diaz O, Deloire A, Azocar O, Baguet J, Le Breton M.... (2011) IRGM is a common target of RNA viruses that subvert the autophagy network. PLoS pathogens, 7(12). PMID: 22174682  

Er, E., Oliver, L., Cartron, P., Juin, P., Manon, S., & Vallette, F. (2006) Mitochondria as the target of the pro-apoptotic protein Bax. Biochimica et Biophysica Acta (BBA) - Bioenergetics, 1757(9-10), 1301-1311. DOI: 10.1016/j.bbabio.2006.05.032  

Richetta C, Grégoire IP, Verlhac P, Azocar O, Baguet J, Flacher M, Tangy F, Rabourdin-Combe C, & Faure M. (2013) Sustained autophagy contributes to measles virus infectivity. PLoS pathogens, 9(9). PMID: 24086130  

Berger SB, Romero X, Ma C, Wang G, Faubion WA, Liao G, Compeer E, Keszei M, Rameh L, Wang N.... (2010) SLAM is a microbial sensor that regulates bacterial phagosome functions in macrophages. Nature immunology, 11(10), 920-7. PMID: 20818396  

Xia M, Meng G, Li M, & Wei J. (2014) Mitophagy in Viral Infections. DNA and cell biology. PMID: 25050805  

Kang R, Zeh HJ, Lotze MT, & Tang D. (2011) The Beclin 1 network regulates autophagy and apoptosis. Cell death and differentiation, 18(4), 571-80. PMID: 21311563  

Bejarano E, Yuste A, Patel B, Stout RF Jr, Spray DC, & Cuervo AM. (2014) Connexins modulate autophagosome biogenesis. Nature cell biology, 16(5), 401-14. PMID: 24705551  

Xia M, Gonzalez P, Li C, Meng G, Jiang A, Wang H, Gao Q, Debatin KM, Beltinger C, & Wei J. (2014) Mitophagy enhances oncolytic measles virus replication by mitigating DDX58/RIG-I-like receptor signaling. Journal of virology, 88(9), 5152-64. PMID: 24574393  

  • September 8, 2014
  • 01:17 PM
  • 65 views

Fingertips can actually perform calculations

by Usman Paracha in SayPeople

Main Point:

Nerve endings on our fingertips have the same ability of performing complex neural computations as we can find in our brain.

Published in:

Nature Nanotechnology

Study Further:

Researchers have found that our fingertips are able to differentiate the edges and this process of getting knowledge of orientation of edges is performed by both touch and visual senses. Most of these senses and computations occur in the brain as it contains cells of both touch and see that are s........ Read more »

  • September 8, 2014
  • 10:41 AM
  • 80 views

Coping with Stress – Some Essential Constructs

by Vivek Misra in The UberBrain

Anxiety, insomnia, muscle tension, fatigue, high blood pressure, and anger are just some of the symptoms of stress. Stress not only affects our body, but also our behavior that can lead to social withdrawal. This presentation will explore the nature of our mind and the various factors in our lives that cause us stress. We will learn simple meditation techniques that can nourish the mind which will lead to increased focus, greater productivity, and improved relationships. ~ Pandi Gadadhara Pandi,........ Read more »

  • September 8, 2014
  • 08:00 AM
  • 72 views

I’ll Wager That You Bet On Football, Or Maybe Football

by Mark E. Lasbury in The 'Scope

Betting on American football and football proper is a trillion dollar a year industry. Why do only 4% of gamblers become addicted. Some of it is actually due to the games themselves. New research is showing that a belief in your knowledge of the game and the “near miss” wherein you almost win your bet, are strong factors in dopamine signaling in the reward centers of the brain.... Read more »

Anselme P, & Robinson MJ. (2013) What motivates gambling behavior? Insight into dopamine's role. Frontiers in behavioral neuroscience, 182. PMID: 24348355  

Huberfeld R, Gersner R, Rosenberg O, Kotler M, & Dannon PN. (2013) Football gambling three arm-controlled study: gamblers, amateurs and laypersons. Psychopathology, 46(1), 28-33. PMID: 22890307  

Khazaal Y, Chatton A, Billieux J, Bizzini L, Monney G, Fresard E, Thorens G, Bondolfi G, El-Guebaly N, Zullino D.... (2012) Effects of expertise on football betting. Substance abuse treatment, prevention, and policy, 18. PMID: 22578101  

Zhou K, Tang H, Sun Y, Huang GH, Rao LL, Liang ZY, & Li S. (2012) Belief in luck or in skill: which locks people into gambling?. Journal of gambling studies / co-sponsored by the National Council on Problem Gambling and Institute for the Study of Gambling and Commercial Gaming, 28(3), 379-91. PMID: 21894576  

Grötsch P, Lange C, Wiesbeck GA, & Lang U. (2013) Pathological Gambling Induced by Dopamine Antagonists: A Case Report. Journal of gambling studies / co-sponsored by the National Council on Problem Gambling and Institute for the Study of Gambling and Commercial Gaming. PMID: 24356928  

  • September 8, 2014
  • 07:02 AM
  • 88 views

Does Face-to-Face Interaction Promote Honesty?

by Rita Handrich in The Jury Room

I listen to a lot of audiobooks while traveling. But sometimes I want something less lengthy than a full book and so I turn to podcasts. Recently, I was on a plane and turned on an episode of the NPR TED Radio Hour podcast on Why We Lie. It’s an interesting and wide-ranging look at […]

Related posts:
Never trust a man with a wide face
I can tell from your face that you are suicidal
A law firm’s financial success & the managing partners’ face


... Read more »

  • September 8, 2014
  • 05:11 AM
  • 56 views

Why your team should appoint a "meta-knowledge" champion - one person who's aware of everyone else's area of expertise

by BPS Research Digest in BPS Research Digest

Being on top of "who knows what" is crucial for any team. If I were scheduled to meet a new client from an unfamiliar industry, it would be handy to know that my office-mate had worked in that area for years and could offer me some tips. But how is this team meta-knowledge (knowledge of who knows what) best handled? New research suggests teams, especially those composed of specialists, gain an advantage when they concentrate this information in the hands of one person instead of spreading it thi........ Read more »

  • September 8, 2014
  • 04:22 AM
  • 68 views

Homocysteine, MTHFR and schizophrenia studied AND meta-analysed

by Paul Whiteley in Questioning Answers

"Our study suggests that increased plasma total homocysteine levels may be associated with an increased risk of schizophrenia". Further: "The meta-analysis of the Japanese genetic association studies demonstrated a significant association between the MTHFR C677T polymorphism and schizophrenia".MTHFR (again!) @ Paul WhiteleySo said the results of the study and meta-analysis carried out by Akira Nishi and colleagues [1] (open-access) looking at the 'big H' alongside everyone's genetic Scrabbl........ Read more »

  • September 8, 2014
  • 02:41 AM
  • 65 views

A Dangerous New Dish

by The Neurocritic in The Neurocritic

Bibimbop Brugmansia ** Do NOT try this at home.Edible flowers can make for a beautiful garnish on salads and trendy Brooklyn cocktails, but those decorative flourishes can be a disaster for the oblivious amateur. An unusual case report in BMC Research Notes summarizes what happens when you sprinkle toxic flower petals on your bibimbop (Kim et al., 2014).A 64 year old Koren woman came to the emergency room with incoherent speech and fluctuations in attention, orientation and comprehension. She ha........ Read more »

Evans Schultes, R., & Plowman, T. (1979) The ethnobotany of Brugmansia. Journal of Ethnopharmacology, 1(2), 147-164. DOI: 10.1016/0378-8741(79)90004-7  

  • September 7, 2014
  • 09:18 PM
  • 49 views

The effect of forefoot varus on the hip and knee and the effect of the hip and knee on forefoot supinatus …

by Craig Payne in Running Research Junkie

The effect of forefoot varus on the hip and knee and the effect of the hip and knee on forefoot supinatus …... Read more »

  • September 7, 2014
  • 03:30 PM
  • 50 views

Can You Hear Me Now?

by Kyle Harris in Sports Medicine Research (SMR): In the Lab & In the Field

Take Home Message: The use of a tuning fork in ruling out fractures is not currently recommended due to low diagnostic accuracy. Little clinical standards, low study quality and small sample size limits the results therefore more standardization and training should be done to improve its clinical efficiency.

In some situations radiographic imaging is not readily available and clinicians must attempt to assess an injury with other tools such as a tuning fork. Unfortunately, the diagnostic accu........ Read more »

  • September 7, 2014
  • 01:46 PM
  • 68 views

A new Hope for Muscle Wasting Diseases

by Gabriel in Lunatic Laboratories

Muscle wasting diseases can be difficult to watch. They are typically slow and have a very painful progression, some to the point of not even being able to breath on ones own. But new research might change all that. Scientists have developed a novel technique to promote tissue repair in damaged muscles. The technique also creates a sustainable pool of muscle stem cells needed to support multiple rounds of muscle repair.... Read more »

Vittorio Sartorelli, & Alessandra Sacco. (2014) STAT3 signaling controls satellite cell expansion and skeletal muscle repair. Nature Medicine. info:/10.1038/nm.3656

  • September 7, 2014
  • 10:03 AM
  • 67 views

Fist Bump, Don't Handshake

by Viputheshwar Sitaraman in Draw Science

Fist bumps minimize contact time and surface area, diminishing germ transfer in terms of greetings--especially compared to handshakes.... Read more »

  • September 6, 2014
  • 06:34 PM
  • 68 views

Clustering of foot strike patterns when running

by Craig Payne in Running Research Junkie

Clustering of foot strike patterns when running... Read more »

  • September 6, 2014
  • 06:22 PM
  • 90 views

Is the Internet of Things the Real Thing?

by Aurametrix team in Health Technologies

The Internet of Things: an exciting new world with a digital nervous system or a nightmare where objects take decisions while we are unconscious?15 years ago, when the term was first coined, it was about assigning everything around us a unique identity with RFID tags, to enable all material things to talk to each other and save us time for gathering and using information. As RFID tags dropped below 1 cent cost, and sensors, modems and devices are getting smaller, smarter and cheaper, this vision........ Read more »

Ashton K. (2009) That 'Internet of Things' Thing, in the real world things matter more than ideas. RFID Journal. info:/

Schreier G. (2014) The internet of things for personalized health. Studies in health technology and informatics, 22-31. PMID: 24851958  

Perera, C., Zaslavsky, A., Christen, P., & Georgakopoulos, D. (2014) Sensing as a service model for smart cities supported by Internet of Things. Transactions on Emerging Telecommunications Technologies, 25(1), 81-93. DOI: 10.1002/ett.2704  

  • September 6, 2014
  • 02:11 PM
  • 53 views

Unpacking Recovery Part 5: Clinical Recovery without a Clinic?

by Andrea in Science of Eating Disorders


It can be somewhat controversial to suggest that untreated recovery from eating disorders is possible. Certainly, people have varied opinions about whether someone can enact the difficult behavioral and attitudinal changes necessary to recover without the help of (at the very least) a therapist and a dietitian. Nonetheless, we still hear stories about individuals who consider themselves recovered without having sought out external sources of professional support.
When I think about untreat........ Read more »

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