What do real fitness landscapes look like? Do they look more like the image on the left, a nearly-neutral holey fitness landscape, or the one on the right, a rugged fitness landscape with many distinct peaks? - See more at: http://pleiotropy.fieldofscience.com/2014/03/evolutionary-dynamics-in-holey-fitness.html#sthash.eTuURlc7.dpuf... Read more »
Gavrilets S, & Gravner J. (1997) Percolation on the fitness hypercube and the evolution of reproductive isolation. Journal of theoretical biology, 184(1), 51-64. PMID: 9039400
Gavrilets S. (1997) Evolution and speciation on holey adaptive landscapes. Trends in ecology , 12(8), 307-12. PMID: 21238086
Østman B, & Adami C. (2013) Predicting evolution and visualizing high-dimensional fitness landscapes. Recent Advances in the Theory and Application of Fitness Landscapes" (A. Engelbrecht and H. Richter, eds.). Springer Series in Emergence, Complexity, and Computation. DOI: 10.1007/978-3-642-41888-4_18
An embryonic stem cell differentiating into a neuronal cell under the microscope.Credit: Anne Rupprecht/Vetmeduni ViennaCells have a metabolism that can be altered according to its function and requirements. If cellular metabolism is disturbed, it can lead to disease of the entire organism. Now, researchers at the University of Veterinary Medicine in Vienna say that they have discovered that the uncoupling proteins UCP2 and UPC4 are involved in different types of cellular metabolism.The protein........ Read more »
Rupprecht A, Sittner D, Smorodchenko A, Hilse KE, Goyn J, Moldzio R, Seiler AE, Bräuer AU, & Pohl EE. (2014) Uncoupling Protein 2 and 4 Expression Pattern during Stem Cell Differentiation Provides New Insight into Their Putative Function. PloS one, 9(2). PMID: 24523901
A paper just out in the journal Psychological Science says that: Women Can Keep the Vote: No Evidence That Hormonal Changes During the Menstrual Cycle Impact Political and Religious Beliefs This eye-catching title heads up an article that’s interesting in more ways than you’d think. According to the paper, authors Christine Harris and Laura Mickes […]The post Hormones and Women Voters: A Very Modern Scientific Controversy appeared first on Neuroskeptic.... Read more »
Harris, C., & Mickes, L. (2014) Women Can Keep the Vote: No Evidence That Hormonal Changes During the Menstrual Cycle Impact Political and Religious Beliefs. Psychological Science. DOI: 10.1177/0956797613520236
Durante, K., Arsena, A., & Griskevicius, V. (2014) Fertility Can Have Different Effects on Single and Nonsingle Women: Reply to Harris and Mickes (2014). Psychological Science. DOI: 10.1177/0956797614524422
Many scientists are hopeful that studying aberrant epigenetic patterns will help us find promising biomarkers for early diagnosis and prognosis of carcinogenesis. Among such markers, there has recently been heightened interest in 5-hydroxymethylcytosine (5-hmC), which is an enzymatically-modified form of 5-methylcytosine (5-mC). A group of researchers in Europe investigated changes in 5-mC as well as ...The post DNA Hydroxymethylation as an Up-and-Coming Epigenetic Biomarker for Liver Cancer........ Read more »
Thomson JP, Hunter JM, Lempiäinen H, Müller A, Terranova R, Moggs JG, & Meehan RR. (2013) Dynamic changes in 5-hydroxymethylation signatures underpin early and late events in drug exposed liver. Nucleic acids research, 41(11), 5639-54. PMID: 23598998
A big step in the development of next-generation fuel cells and water-alkali electrolyzers has been achieved with the discovery of a new class of bimetallic nanocatalysts that are an order of magnitude higher in activity than the target set by the U.S. Department of Energy (DOE) for 2017.... Read more »
Chen, C., Kang, Y., Huo, Z., Zhu, Z., Huang, W., Xin, H., Snyder, J., Li, D., Herron, J., Mavrikakis, M.... (2014) Highly Crystalline Multimetallic Nanoframes with Three-Dimensional Electrocatalytic Surfaces. Science. DOI: 10.1126/science.1249061
Thirteen-year old, Girl Scout Danielle Lei is making bank on cookie sales by setting up shop outside of a legal marijuana dispensary in San Francisco. Selling an astounding 117 boxes of cookies in 2 hours, Danielle and her mother had to restock supplies after just 45 minutes! While the Colorado Girl Scouts organization is frowning on this practice – issuing a statement last month effectively banning sales outside of pot shops – this mother-daughter duo’s entrepreneurial gumptio........ Read more »
Soria-Gómez Edgar, Bellocchio Luigi, Reguero Leire, Lepousez Gabriel, Martin Claire, Bendahmane Mounir, Ruehle Sabine, Remmers Floor, Desprez Tifany, & Matias Isabelle. (2014) The endocannabinoid system controls food intake via olfactory processes. Nature neuroscience. PMID: 24509429
An international team of scientists led by physicists from the University of York has paved the way for a new class of magnetic materials and devices with improved performance and power efficiency.... Read more »
Evans, R., Ostler, T., Chantrell, R., Radu, I., & Rasing, T. (2014) Ultrafast thermally induced magnetic switching in synthetic ferrimagnets. Applied Physics Letters, 104(8), 82410. DOI: 10.1063/1.4867015
We often dream about what we've been doing and who we've been with, so it should come as little surprise to discover many psychotherapists dream about their clients. In fact a new study reports that nearly 70 per cent of thirteen participating therapists said that they'd had such dreams.Psychologist Clara Hill and her colleagues asked the 13 student psychotherapists to keep dream journals for the duration of the time they worked at a community clinic - either one or two years. The number of drea........ Read more »
Hill CE, Knox S, Crook-Lyon RE, Hess SA, Miles J, Spangler PT, & Pudasaini S. (2014) Dreaming of you: Client and therapist dreams about each other during psychodynamic psychotherapy. Psychotherapy research : journal of the Society for Psychotherapy Research. PMID: 24387006
The RASopathies are a class of developmental disorders caused by a genetic mutation in the Ras signaling pathway and associated mitogen-activated protein kinases that control the cell cycle, differentiation and senescence. These diseases encompass a diverse set of clinical syndromes including neurofibromatosis type 1 and Noonan syndrome. Although the pathophysiological manifestations of these conditions are diverse, they share some common phenotypic features. The prevalence of pulmonary hyperten........ Read more »
Krishna S. Vyas, Jacqueline A. Noonan. (2014) Pulmonary Hypertension in the RASopathies. Journal of Cardiology and Vascular Medicine, 2(1), 1-6. info:/2: 101
Is the rearfoot pattern the most frequently foot strike pattern among recreational shod distance runners?... Read more »
de Almeida, M., Saragiotto, B., Yamato, T., & Lopes, A. (2014) Is the rearfoot pattern the most frequently foot strike pattern among recreational shod distance runners?. Physical Therapy in Sport. DOI: 10.1016/j.ptsp.2014.02.005
This month’s Nature Methods issue has several interesting imaging items & articles, including two super-resolution reviews, two optogenetics articles, and more. This post will be dedicated to three items in the “tools in brief” section. Blue transcription Optogenetics usually refers to … Continue reading →... Read more »
Tools in brief. (2014) Chemical biology: Optimized optogenetic gene expression. Nature Methods, 11(3), 230-230. DOI: 10.1038/nmeth.2867
Tools in brief. (2014) Sensors and probes: Expanding Spinach2's spectral properties. Nature Methods, 11(3), 230-230. DOI: 10.1038/nmeth.2865
Pu K, Shuhendler AJ, Jokerst JV, Mei J, Gambhir SS, Bao Z, & Rao J. (2014) Semiconducting polymer nanoparticles as photoacoustic molecular imaging probes in living mice. Nature nanotechnology. PMID: 24463363
Motta-Mena LB, Reade A, Mallory MJ, Glantz S, Weiner OD, Lynch KW, & Gardner KH. (2014) An optogenetic gene expression system with rapid activation and deactivation kinetics. Nature chemical biology, 10(3), 196-202. PMID: 24413462
Song W, Strack RL, Svensen N, & Jaffrey SR. (2014) Plug-and-Play Fluorophores Extend the Spectral Properties of Spinach. Journal of the American Chemical Society, 136(4), 1198-201. PMID: 24393009
Strack RL, Disney MD, & Jaffrey SR. (2013) A superfolding Spinach2 reveals the dynamic nature of trinucleotide repeat-containing RNA. Nature methods, 10(12), 1219-24. PMID: 24162923
Ultraviolet light (UV) has not only harmful effects on molecules and biological tissue like human skin but it also can impair the performance of organic solar cells upon long-term exposure. Researchers of Kiel University and Helmholtz-Zentrum Geesthacht have now developed a so-called plasmonic metamaterial, which is compatible with solar technology and completely absorbs UV light—despite being only 20 nanometers thin.... Read more »
Hedayati, M., Zillohu, A., Strunskus, T., Faupel, F., & Elbahri, M. (2014) Plasmonic tunable metamaterial absorber as ultraviolet protection film. Applied Physics Letters, 104(4), 41103. DOI: 10.1063/1.4863202
Child with microtiaA new study by researchers at the Great Ormond Street Hospital (GOSH) and the UCL Institute of Child Health (ICH) shows that adipose (fat) derived stem cells may be a viable alternative to the currently used approaches for facial cartilage reconstruction, like ear and nose reconstruction.GOSH already has a good track record of successfully treating patients born with a malformed or missing ear, a condition known as microtia. The two-stage ear reconstruction takes cartilage fro........ Read more »
Guasti L, Vagaska B, Bulstrode NW, Seifalian AM, & Ferretti P. (2014) Chondrogenic differentiation of adipose tissue-derived stem cells within nanocaged POSS-PCU scaffolds: A new tool for nanomedicine. Nanomedicine : nanotechnology, biology, and medicine, 10(2), 279-89. PMID: 24008020
Researchers from North Carolina State University have developed a “superabsorbing” design that may significantly improve the light absorption efficiency of thin film solar cells and drive down manufacturing costs.... Read more »
Objects that belonged to famous personalities are very wanted. People pay incredibly high prices to obtain them. Researchers found that the price of an object was influenced by the estimated amount of physical contact that the celebrity had with it. Two theories may explain this finding. ... Read more »
Newman, G., & Bloom, P. (2014) Physical contact influences how much people pay at celebrity auctions. Proceedings of the National Academy of Sciences. DOI: 10.1073/pnas.1313637111
Individuals with schizophrenia or bipolar disorder are at higher risk for obesity.This risk may be related to physical inactivity, diet or the weight gain commonly associated with psychotropic drug use.Few clinical trials for weight loss have targeted individuals with serious mental illness (SMI). This population may pose specific challenges in recruitment, adherence and outcome.Gail Daumit and colleagues recently published a randomized clinical trial of behavioral weight loss in a cohort with S........ Read more »
Daumit GL, Dickerson FB, Wang NY, Dalcin A, Jerome GJ, Anderson CA, Young DR, Frick KD, Yu A, Gennusa JV 3rd.... (2013) A behavioral weight-loss intervention in persons with serious mental illness. The New England journal of medicine, 368(17), 1594-602. PMID: 23517118
Scientists have uncovered a host of pathological consequences in liver- and mitochondrial-pathways in the absence of Bmal1. These studies lend further credence to Bmal1 being important for rhythms of metabolism. These critters are certainly no star athletes. ... Read more »
Peek CB, Affinati AH, Ramsey KM, Kuo HY, Yu W, Sena LA, Ilkayeva O, Marcheva B, Kobayashi Y, Omura C.... (2013) Circadian clock NAD cycle drives mitochondrial oxidative metabolism in mice. Science (New York, N.Y.), 342(6158), 1243417. PMID: 24051248
What do you see when you meditate? Is it the back of your eyelids, a boring spot on the floor just a few feet in front of you? Or is it perhaps something more startling, like little pinpricks of light, or a sense that the world is glowing?
If you have seen those lights, don’t worry; you’re not hallucinating. Or rather, you are hallucinating, in a very strict sense of the word, and that may indicate just how far your meditation practice has progressed.... Read more »
Lindahl JR, Kaplan CT, Winget EM, & Britton WB. (2014) A phenomenology of meditation-induced light experiences: traditional buddhist and neurobiological perspectives. Frontiers in Psychology, 973. PMID: 24427148
Most of us realize that real life stalking is a serious issue and very frightening to the victim, whether male or female and whether young or old. But what about cyber stalking? While research on real life stalking has grown over the past two decades, actual research on cyber stalking is sparse–despite ever-increasing depictions on […]
Are female stalkers less likely to be violent than male stalkers?
If your jurors are happy, will they blame the victim less?
Who cares........ Read more »
Dreßing, H., Bailer, J., Anders, A., Wagner, H., & Gallas, C. (2014) Cyberstalking in a Large Sample of Social Network Users: Prevalence, Characteristics, and Impact Upon Victims. Cyberpsychology, Behavior, and Social Networking, 17(2), 61-67. DOI: 10.1089/cyber.2012.0231
Kingdom: AnimaliaPhylum: MolluscaClass: CephalopodaOrder: TeuthidaFamily: PromachoteuthidaeGenus: PromachoteuthisSpecies: Promachoteuthis sulcusConservation Status: UnknownCommon Names: The squid with human teethThis weird, alien looking creature is called Promachoteuthis sulcus. It is a rare, newly discovered deep-sea squid, best known for its human-like mouth. The species is only known by one specimen that was caught in 2007, in the nets of the German r........ Read more »
Young, R., Vecchione, M., & Roper, C. (2007) A new genus and three new species of decapodiform cephalopods (Mollusca: Cephalopoda). Reviews in Fish Biology and Fisheries, 17(2-3), 353-365. DOI: 10.1007/s11160-007-9044-z
Do you write about peer-reviewed research in your blog? Use ResearchBlogging.org to make it easy for your readers — and others from around the world — to find your serious posts about academic research.
If you don't have a blog, you can still use our site to learn about fascinating developments in cutting-edge research from around the world.
Research Blogging is powered by SMG Technology.
To learn more, visit seedmediagroup.com.