A regular theme here at Neuroskeptic is the worrying issue of head movement during brain scans. We've seen that motion can alter measures of functional and structural connectivity, and that common approaches to dealing with this problem may be inadequate.
Now a new study reveals that even measures of the gross structure of the brain can be biased by excessive motion: Head motion during MRI acquisition reduces gray matter volume and thickness estimates.
Harvard neurologists Martin Reuter ... Read more »
Reuter M, Tisdall MD, Qureshi A, Buckner RL, van der Kouwe AJ, & Fischl B. (2014) Head motion during MRI acquisition reduces gray matter volume and thickness estimates. NeuroImage, 107-115. PMID: 25498430
Did you know that fruit flies sleep? There are actually a lot of similarities between sleep in fruit flies and sleep in humans and other mammals. For example… Image modified from Colwell, 2007 Like us, fruit flies get most of their sleep at night, and they also have an afternoon slump (although unlike us, they […]... Read more »
Potdar Sheetal. (2013) Lessons From Sleeping Flies: Insights from Drosophila melanogaster on the Neuronal Circuitry and Importance of Sleep . Journal of Neurogenetics, 27(1-2), 23-42. DOI: http://dx.doi.org/10.3109/01677063.2013.791692
Koh K., M. N. Wu, Z. Yue, C. J. Smith, & A. Sehgal. (2008) Identification of SLEEPLESS, a Sleep-Promoting Factor. Science, 321(5887), 372-376. DOI: http://dx.doi.org/10.1126/science.1155942
Liu Weijie, Beika Lu, & Aike Guo. (2008) amnesiac regulates sleep onset and maintenance in Drosophila melanogaster. Biochemical and Biophysical Research Communications, 372(4), 798-803. DOI: http://dx.doi.org/10.1016/j.bbrc.2008.05.119
Otters don’t tend to be very visible to us, but they are more abundant than we might perceive them to be. Otters mostly live in isolation of one another, yet they manage to remotely communicate to one another without the aid of modern technology that we so often depend upon for communication.
On this blog, I previously wrote how otters communicate with one another using their spraints (faeces). They use them to mark their territory and to leave messages for other otters. As part of the rese........ Read more »
Kean, E., Chadwick, E., & Müller, C. (2014) Scent signals individual identity and country of origin in otters. Mammalian Biology - Zeitschrift für Säugetierkunde. DOI: 10.1016/j.mambio.2014.12.004
by Rita Handrich in The Jury Room
We are again honored by our inclusion in the ABA Blawg 100 list for 2014. If you value this blog, today is the last day to vote for us here in the Litigation Category. Is this perhaps the anti-reptile theory? We don’t know, but it is potentially a powerful stealth weapon for cases where your opponent is attempting […]
Simple Jury Persuasion: In the face of ambiguity, we just make stuff up!
Simple Jury Persuasion: “That was the witness who spoke so sadly”
Simp........ Read more »
Norman L, Lawrence N, Iles A, Benattayallah A, & Karl A. (2014) Attachment-security priming attenuates amygdala activation to social and linguistic threat. Social Cognitive and Affective Neuroscience. PMID: 25326039
Bipolar disorder appearing again on this blog this week? It's just the way that the papers fall...With a title like: 'Increased uric acid levels in bipolar disorder subjects during different phases of illness' I was hardly likely to pass up the opportunity to discuss the paper by Umberto Albert and colleagues  and their suggestion that there may be a lot more to see when it comes to "a purinergic dysfunction associated with BD [bipolar disorder]".I lost the defuser gun when I mispla........ Read more »
Albert U, De Cori D, Aguglia A, Barbaro F, Bogetto F, & Maina G. (2014) Increased uric acid levels in bipolar disorder subjects during different phases of illness. Journal of affective disorders, 170-175. PMID: 25462413
Tuberous sclerosis complex (TSC) is caused by autosomal dominant inactivating mutations in either the TSC1 or TSC2 genes, and patients are predisposed to developing tumours in the brain, eyes, heart, skin, lungs and kidneys throughout their lifetime. While more than … Continue reading →... Read more »
Tyburczy ME, Jozwiak S, Malinowska IA, Chekaluk Y, Pugh TJ, Wu CL, Nussbaum RL, Seepo S, Dzik T, Kotulska K.... (2014) A shower of second hit events as the cause of multifocal renal cell carcinoma in Tuberous Sclerosis Complex. Human molecular genetics. PMID: 25432535
The FIFA11 program reduced injuries and improved functional performance. It is more effective if compliance and adherence are high, both of which are better if a coach educated on the program administers the program to the team.... Read more »
Barengo, N., Meneses-Echávez, J., Ramírez-Vélez, R., Cohen, D., Tovar, G., & Bautista, J. (2014) The Impact of the FIFA 11 Training Program on Injury Prevention in Football Players: A Systematic Review. International Journal of Environmental Research and Public Health, 11(11), 11986-12000. DOI: 10.3390/ijerph111111986
As December rolls into its second half, and the days warm up - or cool down - depending on where you are situated on the globe, we wanted to say thank you for joining us in 2014 - we are continually blown away with the popular and supportive community we have around us at Do You Believe in Dog? here on the blog, on Facebook and also on Twitter. Taking our lead from Companion Animal Psychology, we decided to jump into some statistics (because hey, we are scientists!) to see wh........ Read more »
Scanlon Eileen. (2013) Scholarship in the digital age: Open educational resources, publication and public engagement. British Journal of Educational Technology, 45(1), 12-23. DOI: http://dx.doi.org/10.1111/bjet.12010
Stilgoe J., & J. Wilsdon. (2014) Why should we promote public engagement with science?. Public Understanding of Science, 23(1), 4-15. DOI: http://dx.doi.org/10.1177/0963662513518154
Effect of shoe drop on running mechanics... Read more »
Chambon N, Delattre N, Guéguen N, Berton E, & Rao G. (2014) Shoe drop has opposite influence on running pattern when running overground or on a treadmill. European journal of applied physiology. PMID: 25501676
While the anti-vaccine movement enjoys the simple (and very wrong) answer to the cause of autism, there are people who want the actual truth. This drive had lead to a slew of causes (and risk factors) for autism in recent times. Now scientists have found that very small segments of genes called “microexons” influence how proteins interact with each other in the nervous system. In turn, this opens up a new line of research into the cause of autism.... Read more »
Irimia, M., Weatheritt, R., Ellis, J., Parikshak, N., Gonatopoulos-Pournatzis, T., Babor, M., Quesnel-Vallières, M., Tapial, J., Raj, B., O’Hanlon, D.... (2014) A Highly Conserved Program of Neuronal Microexons Is Misregulated in Autistic Brains. Cell, 159(7), 1511-1523. DOI: 10.1016/j.cell.2014.11.035
Increased sea temperature due to climate change can influence the distribution, abundance and seasonal timing of zooplankton. Changing zooplankton dynamics might in turn impact the higher trophic levels, such as fish and seabirds, feeding on these animals. In a recent paper, we show that temperature variation in the Atlantic waters of the Norwegian Sea and Barents Sea might have stronger effects on the abundance of the younger than older development stages of Calanus fin........ Read more »
Kvile, K., Dalpadado, P., Orlova, E., Stenseth, N., & Stige, L. (2014) Temperature effects on Calanus finmarchicus vary in space, time and between developmental stages. Marine Ecology Progress Series, 85-104. DOI: 10.3354/meps11024
Biostars is a site for asking, answering and discussing bioinformatics questions and issues. We are members of the community and find it very useful. Often questions and answers arise at Biostars that are germane to our readers (end users of genomics resources). Every Thursday we will be highlighting one of those items or discussions here […]... Read more »
Forrest Alistair R. R., Michael Rehli, J. Kenneth Baillie, Michiel J. L. de Hoon, Vanja Haberle, Timo Lassmann, Ivan V. Kulakovskiy, Marina Lizio, Masayoshi Itoh, & Robin Andersson. (2014) A promoter-level mammalian expression atlas. Nature, 507(7493), 462-470. DOI: http://dx.doi.org/10.1038/nature13182
Severin Jessica, Jayson Harshbarger, Hideya Kawaji, Carsten O Daub, Yoshihide Hayashizaki, Nicolas Bertin, & Alistair R R Forrest. (2014) Interactive visualization and analysis of large-scale sequencing datasets using ZENBU. Nature Biotechnology, 32(3), 217-219. DOI: http://dx.doi.org/10.1038/nbt.2840
The holiday season is upon us, and that means that many of us are thinking about gifts. As I’ve been wrapping the presents I’ve bought for my family, I’ve been […]... Read more »
King, J. (2004) Grave-Goods as Gifts in Early Saxon Burials (ca. AD 450-600). Journal of Social Archaeology, 4(2), 214-238. DOI: 10.1177/1469605304041076
Teacher training doesn't usually include a module on how to arrange the seating of pupils. Perhaps it should - a new study by psychologists finds that where children are placed in the classroom is associated with how well-liked they are by their classmates.Yvonne van den Berg and Antonius Cillessen studied 34 classrooms at 27 elementary schools in The Netherlands. The 336 participating pupils had an average age of 11, and 47 per cent of them were boys. In all classrooms, it was the school policy........ Read more »
van den Berg, Y., & Cillessen, A. (2015) Peer status and classroom seating arrangements: A social relations analysis. Journal of Experimental Child Psychology, 19-34. DOI: 10.1016/j.jecp.2014.09.007
"Increased autistic characteristics found in adults with epilepsy without an ASD [autism spectrum disorder] diagnosis suggest that epilepsy syndromes may incorporate behavioral aspects of autism in the absence of some of its core cognitive features."Contrariwise, if you think we're alive you ought to speak to us.That was the intriguing finding reported by Sally Ann Wakeford and colleagues  who examined test performance on the Autism Spectrum Quotient (AQ) and "systemizing ........ Read more »
Metabolic syndrome is linked with an increased frequency and severity of lower urinary tract symptoms, but weight loss surgery may lessen these symptoms. The findings, which come from two studies published in BJU International, indicate that urinary problems may be added to the list of issues that can improve with efforts that address altered metabolism.
Lower urinary tract symptoms related to urinary frequency and urgency, bladder leakage, the need to urinate at night, and incomplete bladder........ Read more »
Pashootan, P., Ploussard, G., Cocaul, A., de Gouvello, A., & Desgrandchamps, F. (2014) Association between metabolic syndrome and severity of lower urinary tract symptoms (LUTS): an observational study in a 4666 European men cohort. BJU International. DOI: 10.1111/bju.12931
Despite what you may think, the supposed “explosion” of children diagnosed with autism can directly attributed to better diagnosing techniques and — more importantly — the change of definition to make Autism spectrum disorders more broad. Thankfully more causes of autism have been found, none of them remotely related to vaccines and now scientists have found that chemical modifications to DNA’s packaging—known as epigenetic changes—can activate or repress genes involved in autism s........ Read more »
Gao, Z., Lee, P., Stafford, J., von Schimmelmann, M., Schaefer, A., & Reinberg, D. (2014) An AUTS2–Polycomb complex activates gene expression in the CNS. Nature, 516(7531), 349-354. DOI: 10.1038/nature13921
Ntziachristos, P., Tsirigos, A., Welstead, G., Trimarchi, T., Bakogianni, S., Xu, L., Loizou, E., Holmfeldt, L., Strikoudis, A., King, B.... (2014) Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia. Nature, 514(7523), 513-517. DOI: 10.1038/nature13605
Image credits: frauczepluch.blogspot.com Communications is key in any relationship, particularly that between patients and doctors. So what happens when the two parties don’t speak the same...... Read more »
Patil S, & Davies P. (2014) Use of Google Translate in medical communication: evaluation of accuracy. BMJ (Clinical research ed.). PMID: 25512386
Today a commentary was published in BBS in which the gradual audiomotor evolution (GAE) hypothesis is proposed as an alternative interpretation to the auditory timing mechanisms discussed in the BBS target article by Ackermann et al. (2014). ... Read more »
Ackermann, H., Hage, S., & Ziegler, W. (2014) Brain mechanisms of acoustic communication in humans and nonhuman primates: An evolutionary perspective. Behavioral and Brain Sciences, 1-84. DOI: 10.1017/S0140525X13003099
Merchant, H., & Honing, H. (2013) Are non-human primates capable of rhythmic entrainment? Evidence for the gradual audiomotor evolution hypothesis. Frontiers in Neuroscience, 7(274). info:/
This week’s video tip of the week closes out a series that began last month. I started to explore one gene co-expression tool, which led me to another tool for visualization, and so on. This week’s tool is the final piece that you need to know about if you want to create the kind of […]... Read more »
Wright Derek W., Anton J. Enright, & Tom C. Freeman. (2014) Visualisation of BioPAX Networks using BioLayout Express3D. F1000Research. DOI: http://dx.doi.org/10.12688/f1000research.5499.1
Smoot M. E., J. Ruscheinski, P.-L. Wang, & T. Ideker. (2010) Cytoscape 2.8: new features for data integration and network visualization. Bioinformatics, 27(3), 431-432. DOI: http://dx.doi.org/10.1093/bioinformatics/btq675
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