Post List

  • August 10, 2016
  • 01:30 PM

Is depression in parents, grandparents linked to grandchildren's depression?

by Dr. Jekyll in Lunatic Laboratories

If you read my blog often, it's no surprise I suffer from PTSD, depression, and anxiety issues. Maybe it's from my military service, but maybe it's my father's, or his father's, maybe it's an insidious family legacy that was just never noticed. This is because having both parents and grandparents with major depressive disorder (MDD) was associated with higher risk of MDD for grandchildren, which could help identify those who may benefit from early intervention.

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Myrna M. Weissman, PhD, Obianuju O. Berry, MD, MPH, Virginia Warner, DrPH, Marc J. Gameroff, PhD, Jamie Skipper, MS, Ardesheer Talati, PhD, Daniel J. Pilowsky, MD, MPH, & Priya Wickramaratne, PhD. (2016) A 30-Year Study of 3 Generations at High Risk and Low Risk for Depression. JAMA Psychiatry . info:/10.1001/jamapsychiatry.2016.1586

  • August 10, 2016
  • 10:00 AM

Dog Bite Strength: It's Not What You Think

by CAPB in Companion Animal Psychology Blog

Scientists tracked down the evidence for a common statement about bite strength in dogs – and found it lacking.Have you ever read comments about the strength of a dog’s jaw when it bites? These statements are often made in relation to certain types of dog, like pit bulls. Maybe some people take it as fact. But what if it’s not true?A recent paper by Dr. Gary Patronek (Cummings School of Veterinary Medicine, Tufts University) et al traced citations in the literature and went back to the ori........ Read more »

  • August 10, 2016
  • 08:55 AM

Gimme Some Dihydrogen Monoxide

by Mark Lasbury in As Many Exceptions As Rules

One cannot over estimate the ways that water affects life on Earth. Beyond its chemical properties, some animals have evolved to substitute water for a rigid skeleton. Hydrostatic skeletons can be used for support, but also as water vascular systems that provide pressure for vascular transport and respiration. A recent review by William H. Kier sheds light on the interactions of different fibers and tissues in water based skeletons. Yet some plants can withstand a loss of 60% of their water, whe........ Read more »

Kier, W. (2012) The diversity of hydrostatic skeletons. Journal of Experimental Biology, 215(8), 1247-1257. DOI: 10.1242/jeb.056549  

  • August 10, 2016
  • 04:30 AM

Hands off the Hands-free Ultrasound If You Are Looking for Deep Heating Effects

by Jane McDevitt in Sports Medicine Research (SMR): In the Lab & In the Field

A hands-free ultrasound unit at 1 MHz failed to increase the temperature deep in the gastrocnemius after 10 minutes.... Read more »

  • August 10, 2016
  • 04:24 AM

No association between [current] mycotoxin exposure and autism

by Paul Whiteley in Questioning Answers

Although research stories stating a link (an association if you will) between condition A and factor X make for interesting reading, not all science is so blessed with such news-worthy findings. That's not to say that 'negative findings' are any less important than the 'hey, we found this...' studies, just that they don't perhaps tend to grab the headlines as much as those finding something.In saying all that I'm standing up for negative findings today and some rather interesting science reporte........ Read more »

  • August 9, 2016
  • 02:41 PM

Want a better memory? Try eating a Mediterranean diet

by Dr. Jekyll in Lunatic Laboratories

It's not a fad diet, it is an actual diet -- as in the way a person eats normally -- and it may do more than just help your waistline. The Mediterranean diet can improve your mind, as well your heart.

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  • August 9, 2016
  • 11:16 AM

Genetics of Depression: Secondary Markers

by William Yates, M.D. in Brain Posts

In my previous post, I highlighted a recent study of genetics and major depression from the 23andMe database.I have had a chance to review this manuscript in more detail. One of the findings of interest involved secondary marker or secondary phenotypes.Fifteen genetic loci were identified in this 23andMe sample using a discovery and replication data set.Secondary phenotypes with the highest correlation with the 17 SNPs identified in the study included (effect) :Taking a selective serotonin reupt........ Read more »

  • August 9, 2016
  • 09:24 AM

Particle Acceleration and heating by turbulent reconnection by L. Vlahos, T. Pisokas, H. Isliker, V. Tsiolis and A. Anastasiadis

by CESRA in Solar Radio Science

Fermi (1949) introduced a fundamental stochastic process to solve the problem of particle energization (heating and/or acceleration) in space and astrophysical plasmas. The initial idea of Fermi with randomly moving scatterers (magnetic clouds), was soon replaced with a spectrum of low amplitude (δΒ/Β... Read more »

by L. Vlahos, T. Pisokas, H. Isliker, V. Tsiolis and A. Anastasiadis. (2016) Particle Acceleration and heating by turbulent reconnection. ApJ. info:/

  • August 9, 2016
  • 02:56 AM

Anxiety spreads across various psychiatric labels

by Paul Whiteley in Questioning Answers

"Comorbid anxiety symptoms are ubiquitous among psychiatric patients with mood or schizophrenia spectrum disorders, and in almost half of them, reportedly severe."So said the findings reported by Karpov and colleagues [1] who sought to put some further research flesh on to the bones of the idea that clinically relevant anxiety symptoms might not be unstrange bedfellows with a variety of other psychiatric labels.Based on the analysis of various patient groups included in the "Helsinki University ........ Read more »

Karpov, B., Joffe, G., Aaltonen, K., Suvisaari, J., Baryshnikov, I., Näätänen, P., Koivisto, M., Melartin, T., Oksanen, J., Suominen, K.... (2016) Anxiety symptoms in a major mood and schizophrenia spectrum disorders. European Psychiatry, 1-7. DOI: 10.1016/j.eurpsy.2016.04.007  

  • August 9, 2016
  • 12:20 AM

Is the drop of a running shoe associated with injury risk?

by Craig Payne in Running Research Junkie

Is the drop of a running shoe associated with injury risk?... Read more »

  • August 8, 2016
  • 03:38 PM

World's worst hickeys: Cupping is weird and potentially dangerous

by Rosin Cerate in Rosin Cerate

In an effort to reduce pain or fix other health problems, some people will submit to having suction temporarily applied to various regions of their skin, usually the neck, shoulders, and back, via a collection of plastic or glass cups. This is known as cupping, and is a great way to embrace your inner Polkaroo.... Read more »

Lin CW, Wang JT, Choy CS, & Tung HH. (2009) Iatrogenic bullae following cupping therapy. Journal of Alternative and Complementary Medicine, 15(11), 1243-1245. PMID: 19922257  

  • August 8, 2016
  • 01:54 PM

Pesticides used to help bees may actually harm them

by Dr. Jekyll in Lunatic Laboratories

Pesticides beekeepers are using to improve honeybee health may actually be harming the bees by damaging the bacteria communities in their guts. The discovery is a concern because alterations can affect the gut's ability to metabolize sugars and peptides, processes that are vital for honeybee health.

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Madhavi Kakumanu, Alison M. Reeves, Troy Anderson, Richard R. Rodrigues, & Mark A. Williams. (2016) Honey bee gut microbiome is altered by in-hive pesticide exposures. Frontiers in Microbiology. info:/10.3389/fmicb.2016.01255

  • August 8, 2016
  • 06:40 AM

Scientific Study Shows Mediums Are Wrong 46.2% of the Time

by The Neurocritic in The Neurocritic

Not a very good showing, eh?Here's our latest study on mediumship: "Prediction of Mortality Based on Facial Characteristics". Available here:— Dean Radin (@DeanRadin) May 21, 2016In the study,“Participants were asked to press a button if they thought the person in a photo was living or deceased. Overall mean accuracy on this task was 53.8%, where 50% was expected by chance (p < 0.004, two-tail). Statistically significant accuracy was independently obtained in 5 of ........ Read more »

Delorme, A., Pierce, A., Michel, L., & Radin, D. (2016) Prediction of Mortality Based on Facial Characteristics. Frontiers in Human Neuroscience. DOI: 10.3389/fnhum.2016.00173  

  • August 8, 2016
  • 03:46 AM

On staff training in the UK autism services sector

by Paul Whiteley in Questioning Answers

I tread carefully in discussing the findings reported by Karola Dillenburger and colleagues [1] (open-access) on the question of "knowledge and training with regards to autism" received by "health, social care, and education staff who work within the statutory autism services sector in the UK." The observation that "an acute lack of autism-specific training that has detrimental impacts" was apparent is a worrying sign indeed.Although not intimately involved in the autism services sector, I ........ Read more »

Dillenburger K, McKerr L, Jordan JA, & Keenan M. (2016) Staff Training in Autism: The One-Eyed Wo/Man…. International journal of environmental research and public health, 13(7). PMID: 27438846  

  • August 7, 2016
  • 02:35 PM

Why you're stiff in the morning: Your body suppresses inflammation when you sleep at night

by Dr. Jekyll in Lunatic Laboratories

Feeling stiff first thing in the morning? It's not your imagination, new research has found a protein created by the body's "biological clock" that actively represses inflammatory pathways within the affected limbs during the night. This protein, called CRYPTOCHROME, has proven anti-inflammatory effects in cultured cells and presents new opportunities for the development of drugs that may be used to treat inflammatory diseases and conditions, such as arthritis.

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Hand, L., Hopwood, T., Dickson, S., Walker, A., Loudon, A., Ray, D., Bechtold, D., & Gibbs, J. (2016) The circadian clock regulates inflammatory arthritis. The FASEB Journal. DOI: 10.1096/fj.201600353R  

  • August 7, 2016
  • 11:53 AM

The (surprising) rate of ADHD in Taiwan

by Paul Whiteley in Questioning Answers

The idea that use of the diagnostic label called attention-deficit hyperactivity disorder (ADHD) is on the increase, and pretty significantly so, is quite common-place these days (see here). Appreciating that not everyone is convinced that the increase is necessarily genuine (see here) I would like to discuss some interesting data coming out of the 'big data' country that is Taiwan in the form of the findings reported by Wang and colleagues [1].As regular readers might already know, Taiwan is th........ Read more »

  • August 6, 2016
  • 03:24 PM

Microcephaly discoveries in non-Zika cases explain abnormal brain growth

by Dr. Jekyll in Lunatic Laboratories

Long before Zika virus made it a household word, the birth defect called microcephaly puzzled scientists and doctors -- even as it changed the lives of the babies born with it during the pre-Zika era. But new discoveries reported by an international team of scientists may help explain what happens in the developing brains of babies still in the womb, causing them to be born with small brains and heads.

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Li, H., Bielas, S., Zaki, M., Ismail, S., Farfara, D., Um, K., Rosti, R., Scott, E., Tu, S., Chi, N.... (2016) Biallelic Mutations in Citron Kinase Link Mitotic Cytokinesis to Human Primary Microcephaly. The American Journal of Human Genetics, 99(2), 501-510. DOI: 10.1016/j.ajhg.2016.07.004  

  • August 5, 2016
  • 03:10 PM

From Sci Fi to reality: Unlocking the secret to growing new limbs

by Dr. Jekyll in Lunatic Laboratories

Many lower organisms retain the miraculous ability to regenerate form and function of almost any tissue after injury. Humans share many of our genes with these organisms, but our capacity for regeneration is limited. So scientists are studying the genetics of these organisms to find out how regenerative mechanisms might be activated in humans.

... Read more »

  • August 5, 2016
  • 07:00 AM

Friday Fellow: Beggar’s tick

by Piter Boll in Earthling Nature

by Piter Kehoma Boll What if the cure for cancer has been living in your garden all this time and you have been trying to get rid of it because it is an annoying weed? I cannot assure you that … Continue reading →... Read more »

Chiang, L., Chang, J., Chen, C., Ng, L., & Lin, C. (2003) Anti-Herpes Simplex Virus Activity of Bidens pilosa and Houttuynia cordata. The American Journal of Chinese Medicine, 31(03), 355-362. DOI: 10.1142/S0192415X03001090  

Kviecinski, M., Felipe, K., Schoenfelder, T., de Lemos Wiese, L., Rossi, M., Gonçalez, E., Felicio, J., Filho, D., & Pedrosa, R. (2008) Study of the antitumor potential of Bidens pilosa (Asteraceae) used in Brazilian folk medicine. Journal of Ethnopharmacology, 117(1), 69-75. DOI: 10.1016/j.jep.2008.01.017  

  • August 5, 2016
  • 05:09 AM

Multiple germline mutations in rare inherited cancer syndrome genes

by Joana Guedes in BHD Research Blog

A recent study by Whitworth et al. (2016) reports five new cases of multiple germline mutations in inherited cancer syndrome genes, three of them involve the combination of mutations in FLCN with NF1, TP53, and MSH2, respectively.... Read more »

Whitworth J, Skytte AB, Sunde L, Lim DH, Arends MJ, Happerfield L, Frayling IM, van Minkelen R, Woodward ER, Tischkowitz MD.... (2016) Multilocus Inherited Neoplasia Alleles Syndrome: A Case Series and Review. JAMA oncology, 2(3), 373-9. PMID: 26659639  

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