Yet again, more of the same …... Read more »
Melcher DA, Paquette MR, Schilling BK, & Bloomer RJ. (2016) Joint stiffness and running economy during imposed forefoot strike before and after a long run in rearfoot strike runners. Journal of sports sciences, 1-7. PMID: 27935426
The title of this post reflects the commentary published by Andrew Whitehouse  (open-access) discussing the meaning of the findings reported by Kung and colleagues  who quite categorically stated that there was: "No relationship between prenatal androgen exposure and autistic traits" in their study.OK, androgen exposure and psychology basically refers to the extreme male brain theory and autism which suggests that the so-called over-representation of autism in males is potentiall........ Read more »
Whitehouse AJ. (2016) Commentary: Are we expecting too much from the extreme male brain theory of autism? A reflection on Kung et al. (2016). Journal of child psychology and psychiatry, and allied disciplines, 57(12), 1463-1464. PMID: 27859346
Researchers at the Carnegie Institution of Washington re-examined the Kepler data and determined that it had also been steadily dimming over the course of those four years, on top of its sporadic dips in brightness. For 1,000 days, the rate of dimming observed was constant; then, for 200 days after, its dimming rate suddenly increased by some order of magnitude; finally, for the remaining 200 days, its brightness had remained largely unchanged.... Read more »
Boyajian, T., LaCourse, D., Rappaport, S., & et al. (2016) Planet Hunters IX. KIC 8462852 – where's the flux?. Monthly Notices of the Royal Astronomical Society, 457(4), 3988-4004. DOI: 10.1093/mnras/stw218
One of the factors for violence perpetuation is the transmission of coercitive practices through family generations. The Parceria Project (Projeto Parceria) aims at teaching parenting skills to Brazilian women victims of intimate partner violence and shows that it is possible to intervene in order to contribute to the development of healthier family relationships. … Read More →... Read more »
SANTINI, P., & WILLIAMS, L. (2016) Efeitos de procedimentos para maximizar o bem-estar e a competência parental em mulheres vitimizadas. Estudos de Psicologia (Campinas), 33(4), 711-721. DOI: 10.1590/1982-02752016000400014
Today I bring the findings reported by Chou and colleagues  (open-access available here) to the blogging table and how the research might of the Taiwan National Health Insurance Database (NHIRD) brought it's 'big data' ("n = 23 422 955") to bear on the question: what is the risk of developing schizophrenia where one or more first-degree or other relatives are affected?The answer: "Having an affected co-twin, first-degree relative, second-degree relative, or spouse was associate........ Read more »
Chou IJ, Kuo CF, Huang YS, Grainge MJ, Valdes AM, See LC, Yu KH, Luo SF, Huang LS, Tseng WY.... (2016) Familial Aggregation and Heritability of Schizophrenia and Co-aggregation of Psychiatric Illnesses in Affected Families. Schizophrenia bulletin. PMID: 27872260
Patients who suffer from current or previous symptoms of lower back pain demonstrated lower reach distances in the posterior directions of the Y-Balance Test compared to healthy individuals.... Read more »
Hooper, T., James, C., Brismée, J., Rogers, T., Gilbert, K., Browne, K., & Sizer, P. (2016) Dynamic balance as measured by the Y-Balance Test is reduced in individuals with low back pain: A cross-sectional comparative study. Physical Therapy in Sport, 29-34. DOI: 10.1016/j.ptsp.2016.04.006
When you're doing two things at once - like listening to the radio while driving - your brain organizes itself into two, functionally independent networks, almost as if you temporarily have two brains. That's according to a fascinating new study from University of Wisconsin-Madison neuroscientists Shuntaro Sasai and colleagues. It's called Functional split brain in a driving/listening paradigm
In referring to 'split brains' in their title, Sasai et al. are linking their work to the litera... Read more »
Sasai, S., Boly, M., Mensen, A., & Tononi, G. (2016) Functional split brain in a driving/listening paradigm. Proceedings of the National Academy of Sciences, 201613200. DOI: 10.1073/pnas.1613200113
by Kamil S. Jaron in genome ecology evolution etc
Exploration of variability of human genomes represents a key step in the holy grail of human genetics – to link genotypes with phenotypes, it also provides insights to human evolution and history. For this purpose Exome Aggregation Consortium (ExAC) have … Continue reading →... Read more »
Lek M, Karczewski KJ, Minikel EV, Samocha KE, Banks E, Fennell T, O'Donnell-Luria AH, Ware JS, Hill AJ, Cummings BB.... (2016) Analysis of protein-coding genetic variation in 60,706 humans. Nature, 536(7616), 285-91. PMID: 27535533
Working for both public and private institutions, archaeologists constantly construct and deconstruct narratives about our past, but traditionally publish only a fraction of the sites they excavate and thus destroy. Computers and the internet present a vast range of opportunities for archaeologists to share primary data and foster intercultural online collaborations and reinterpretations of archaeological contexts. ... Read more »
One central concept in the OMA project and other
work we do to infer relationships between genes is that of Hierarchical
Orthologous Groups, or “HOGs” for the initiated.
We’ve written several papers on aspects pertaining to HOGs—how to infer
how to evaluate them, they being
increasingly adopted by orthology
resources, etc.—but there is
still a great deal of confusion as to what HOGs are and why they matter.
Natasha Glover, talented postdoc in the lab,........ Read more »
Altenhoff, A., Gil, M., Gonnet, G., & Dessimoz, C. (2013) Inferring Hierarchical Orthologous Groups from Orthologous Gene Pairs. PLoS ONE, 8(1). DOI: 10.1371/journal.pone.0053786
Boeckmann, B., Robinson-Rechavi, M., Xenarios, I., & Dessimoz, C. (2011) Conceptual framework and pilot study to benchmark phylogenomic databases based on reference gene trees. Briefings in Bioinformatics, 12(5), 423-435. DOI: 10.1093/bib/bbr034
Sonnhammer, E., Gabaldon, T., Sousa da Silva, A., Martin, M., Robinson-Rechavi, M., Boeckmann, B., Thomas, P., Dessimoz, C., & , . (2014) Big data and other challenges in the quest for orthologs. Bioinformatics, 30(21), 2993-2998. DOI: 10.1093/bioinformatics/btu492
Where is the septum?
The term septum, when used in reference to the brain (it is a common anatomical term used to refer to a partition), indicates a subcortical structure in the forebrain that is found near the midline of the brain. The septum in humans can be separated into two structures: the septum pellucidum and septum verum. Each of these is sometimes........ Read more »
Sheehan, T., Chambers, R., & Russell, D. (2004) Regulation of affect by the lateral septum: implications for neuropsychiatry. Brain Research Reviews, 46(1), 71-117. DOI: 10.1016/j.brainresrev.2004.04.009
"Prescription drug use and polypharmacy rates among adults with ASD [autism spectrum disorder] are substantially higher than those in an age-, sex-, and race-matched cohort of adults without ASD."That sentence taken from the paper by Rini Vohra and colleagues  (open-access available here) is probably not likely to win any 'novel findings of the year' awards given the already quite voluminous data published on the medication use and autism (see here for example). What gives the ........ Read more »
Vohra R, Madhavan S, Sambamoorthi U, StPeter C, Poe S, Dwibedi N, & Ajmera M. (2016) Prescription Drug Use and Polypharmacy Among Medicaid-Enrolled Adults with Autism: A Retrospective Cross-Sectional Analysis. Drugs - real world outcomes. PMID: 27873285
by Livia Gerber in Language on the Move
A 2015 article in the New York Post argued that mobile dating apps, such as Tinder and its many clones,...... Read more »
Hobbs, M., Owen, S., & Gerber, L. (2016) Liquid love? Dating apps, sex, relationships and the digital transformation of intimacy. Journal of Sociology. DOI: 10.1177/1440783316662718
Research considers that the diagnosis of congenital malformation may affect maternal mental health during pregnancy. Symptoms of anxiety and depression can occur from the first quarter, impacting also on the family, especially if the communication of the diagnosis is not careful. They conclude that the coping face to this situation and the impact of bad news can be minimized by the pregnant woman's support network. … Read More →... Read more »
CUNHA, A., PEREIRA JUNIOR, J., CALDEIRA, C., & CARNEIRO, V. (2016) Diagnóstico de malformações congênitas: impactos sobre a saúde mental de gestantes. Estudos de Psicologia (Campinas), 33(4), 601-611. DOI: 10.1590/1982-02752016000400004
A recently-published study has now resolved the mystery of the bison bones, with the help of some Ice Age cave artists. It turns out that there once existed, during the Ice Age, a hybrid between the now-extinct aurochs (the beast from which we domesticated the cow) and the equally-extinct steppe bison (basically, the Asian version of the American bison).... Read more »
Soubrier, J., Gower, G., Chen, K., & et al. (2016) Early cave art and ancient DNA record the origin of European bison. Nature Communications, 13158. DOI: 10.1038/ncomms13158
"A total of 22 original papers that examined the association between folic acid supplementation in human pregnancy and neurodevelopment/autism were identified after the screening, with 15 studies showing a beneficial effect of folic acid supplementation on neurodevelopment/autism, 6 studies showed no statistically significant difference, while one study showed a harmful effect in > 5 mg folic acid supplementation/day during pregnancy."That rather long quote taken from the paper published by Y........ Read more »
Gao Y, Sheng C, Xie RH, Sun W, Asztalos E, Moddemann D, Zwaigenbaum L, Walker M, & Wen SW. (2016) New Perspective on Impact of Folic Acid Supplementation during Pregnancy on Neurodevelopment/Autism in the Offspring Children - A Systematic Review. PloS one, 11(11). PMID: 27875541
New research looks at the factors that influence how we feel after euthanizing a pet.The loss of a pet is a difficult process. People’s feelings of grief may be the same as for losing a human family member. New research investigates some of the factors that may affect people’s grief and sorrow after euthanizing a dog or cat.The study, by Sandra Barnard-Nguyen (University of Sydney) et al, is one of the first to use a survey designed specifically to measure people’s responses to loss o........ Read more »
Barnard-Nguyen, S., Breit, M., Anderson, K., & Nielsen, J. (2016) Pet Loss and Grief: Identifying At-risk Pet Owners during the Euthanasia Process. Anthrozoös, 29(3), 421-430. DOI: 10.1080/08927936.2016.1181362
MicroRNAs (miRNAs) are non-coding RNAs, roughly 22 nucleotides in size that are central and negative regulators of gene expression. They exert their functions through base-pairing with the 3’UTR of mRNAs and block expression at the transcriptional and post-transcriptional levels, depending on the perfect or imperfect match in sequences between miRNAs and their target genes. miRNAs are central nodes in a variety of biological processes like cell proliferation, apoptosis, migration and dif........ Read more »
Parodi F, Carosio R, Ragusa M, Di Pietro C, Maugeri M, Barbagallo D, Sallustio F, Allemanni G, Pistillo MP, Casciano I.... (2016) Epigenetic dysregulation in neuroblastoma: A tale of miRNAs and DNA methylation. Biochimica et biophysica acta, 1859(12), 1502-1514. PMID: 27751904
A Blanket high dose vitamin D supplement plan results in elevated levels of vitamin D metabolites after the supplementation is completed. This could result in lower than normal levels of vitamin D, which is the opposite effect of the intended supplementation.... Read more »
Owens DJ, Tang JC, Bradley WJ, Sparks SA, Fraser WD, Morton JP, & Close GL. (2016) Efficacy of High Dose Vitamin D Supplements for Elite Athletes. Medicine and science in sports and exercise. PMID: 27741217
Does non-ionizing radiation pose a health risk? Everyone knows that ionizing radiation, like gamma rays, can cause cancer by damaging DNA. But the scientific consensus is that there is no such risk from non-ionizing radiation such as radiowaves or Wi-Fi.
Yet according to a remarkable new paper from Magda Havas, the risk is real: it's called When theory and observation collide: Can non-ionizing radiation cause cancer?
There are a few remarkable things about this paper but chief among th... Read more »
Havas, M. (2016) When theory and observation collide: Can non-ionizing radiation cause cancer?. Environmental Pollution. DOI: 10.1016/j.envpol.2016.10.018
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