Welcome to Part 2 of my journey to the movie theater. This will make sense if you haven’t read Part 1, but to enjoy the full impact of this visite du cinéma, I suggest you read both. If ya just don’t wanna then here’s a summary: (1) movie tickets are expensive, (2) as far as I can tell, nobody has really done a direct study of why, (3) economists try to explain why all movies cost the same through their “uniform pricing for differentiated goods” theory, (4) as it turns out, variable o........ Read more »
B. Wansink, & S.B. Park. (2001) At the movies: how external cues and perceived taste impact consumption volume. Food Quality and Preference, 69-74. DOI: 10.1016/S0950-3293(00)00031-8
B. Wansink, & J. Kim. (2005) Bad Popcorn in Big Buckets: Portion Size Can Influence Intake as Much as Taste. Journal of Nutrition Education and Behavior, 37(5), 242-245. DOI: 10.1016/S1499-4046(06)60278-9
D. Marchiori, O. Corneille, & O. Klein. (2012) Container size influences snack food intake independently of portion size. Appetite, 814-817. DOI: 10.1016/j.appet.2012.01.015
S. Topolinski, S. Lindner, & A. Freudenberg. (2013) Popcorn in the cinema: Oral interference sabotages advertising effects. Journal of Consumer Psychology. DOI: 10.1016/j.jcps.2013.09.008
Recently we announced our newest training materials on GenoCAD. The introductory tutorial provides a great foundation for understanding the features that are available and how it could help you in the lab. But for those folks who want to take their design skills further–now you can use the GenoCAD Advanced Topics materials to do so. […]... Read more »
Wilson ML., Hertzberg R., Adam L., & Peccoud J. (2011) A step-by-step introduction to rule-based design of synthetic genetic constructs using GenoCAD. Methods Enzymol. DOI: 10.1016/B978-0-12-385120-8.00008-5
Wilson M. L., Okumoto S., Adam L., & Peccoud J. (2013) Development of a domain-specific genetic language to design Chlamydomonas reinhardtii expression vectors. Bioinformatics. DOI: 10.1093/bioinformatics/btt646
In evolutionary theory, a fitness landscape is a map where fitness is a function of either the genotype or the phenotype. The genotype is some description of the genetic make-up of an organism. This can be the DNA or a list of the mutations/alleles, and are discrete variables. ... Read more »
Jasper Franke, Alexander Klözer, J. Arjan G. M. de Visser, & Joachim Krug. (2011) Evolutionary accessibility of mutational pathways. PLoS Computational Biology 7 (8) e1002134 (2011). arXiv: 1103.2479v2
Weissman DB, Desai MM, Fisher DS, & Feldman MW. (2009) The rate at which asexual populations cross fitness valleys. Theoretical population biology, 75(4), 286-300. PMID: 19285994
Østman B, Hintze A, & Adami C. (2012) Impact of epistasis and pleiotropy on evolutionary adaptation. Proceedings. Biological sciences / The Royal Society, 279(1727), 247-56. PMID: 21697174
Basic social skills of African elephants remain impaired decades after surviving devastating experiences. ... Read more »
Shannon G, Slotow R, Durant SM, Sayialel KN, Poole J, Moss C, & McComb K. (2013) Effects of social disruption in elephants persist decades after culling. Frontiers in Zoology, 62. PMID: 24152378
You can hardly turn on the television or radio these days and not hear a discussion about rising gas prices. When most people set out to buy a new car it’s no doubt that fuel efficiency is one of the … Continue reading →... Read more »
Doebbe Anja, Rupprecht Jens, Beckmann Julia, Mussgnug Jan H., Hallmann Armin, Hankamer Ben, & Kruse Olaf. (2007) Functional integration of the HUP1 hexose symporter gene into the genome of C. reinhardtii: Impacts on biological H2 production. Journal of Biotechnology, 131(1), 27-33. DOI: 10.1016/j.jbiotec.2007.05.017
Kruse O. (2005) Improved Photobiological H2 Production in Engineered Green Algal Cells. Journal of Biological Chemistry, 280(40), 34170-34177. DOI: 10.1074/jbc.M503840200
Hankamer Ben, Lehr Florian, Rupprecht Jens, Mussgnug Jan H., Posten Clemens, & Kruse Olaf. (2007) Photosynthetic biomass and H production by green algae: from bioengineering to bioreactor scale-up . Physiologia Plantarum, 131(1), 10-21. DOI: 10.1111/j.1399-3054.2007.00924.x
In the process of domestication, it seems that dogs have become especially attuned to human communication. Does this mean they can cooperate with a human to solve a problem? And what if they need to cooperate with another dog instead? A study in press by Ostojić and Clayton investigates.Photo: Jim Parkin / ShutterstockThe study is based on a “string task” in which two dogs (or a dog and a human) have to pull each end of a string in order to gain access to food that is otherwise out........ Read more »
Ostojic, L, & Clayton, N.S. (2013) Behavioural coordination of dogs in a cooperative problem-solving task with a conspecific and a human partner. Animal Cognition. DOI: 10.1007/s10071-013-0676-1
We are taught and we teach that DNA codes fro the amino acid sequence of specific proteins. But the truth is that often times, the sequence of the mRNA ends of different than that coded by the DNA. In addition to mRNA processing, there is also RNA editing, which can add, subtract, or change the base sequence in a transcript.
New research is showing just how extensive RNA editing is and the powerful role it plays in cellular expression. A new algorithm has been introduced to better predict R........ Read more »
Paz-Yaacov N, Levanon EY, Nevo E, Kinar Y, Harmelin A, Jacob-Hirsch J, Amariglio N, Eisenberg E, & Rechavi G. (2010) Adenosine-to-inosine RNA editing shapes transcriptome diversity in primates. Proceedings of the National Academy of Sciences of the United States of America, 107(27), 12174-9. PMID: 20566853
Takahashi T, Otsuguro K, Ohta T, & Ito S. (2010) Adenosine and inosine release during hypoxia in the isolated spinal cord of neonatal rats. British journal of pharmacology, 161(8), 1806-16. PMID: 20735412
Lenz H, & Knoop V. (2013) PREPACT 2.0: Predicting C-to-U and U-to-C RNA Editing in Organelle Genome Sequences with Multiple References and Curated RNA Editing Annotation. Bioinformatics and biology insights, 1-19. PMID: 23362369
Poulsen HE, Nadal LL, Broedbaek K, Nielsen PE, & Weimann A. (2013) Detection and interpretation of 8-oxodG and 8-oxoGua in urine, plasma and cerebrospinal fluid. Biochimica et biophysica acta. PMID: 23791936
Wang P, Fisher D, Rao A, & Giese RW. (2012) Nontargeted nucleotide analysis based on benzoylhistamine labeling-MALDI-TOF/TOF-MS: discovery of putative 6-oxo-thymine in DNA. Analytical chemistry, 84(8), 3811-9. PMID: 22409256
by amikulak in Daily Observations
In order to be able to make sound health decisions, patients need to understand the risks and the benefits that come with medical treatments, screenings, and lifestyle choices. But many […]... Read more »
The southern beeches used to classified in one genus (Nothofagus) and one family (Nothofagaceae). A new paper argues convincingly that the genus should be divided into four genera.... Read more »
Heenan, P.B.; Smissen, R.D. (2013) Revised circumscription of Nothofagus and recognition of the segregate genera Fuscospora, Lophozonia, and Trisyngyne (Nothofagaceae). Phytotaxa. DOI: 10.11646/phytotaxa.146.1.1
High rotational or low translational traction between footwear and playing surfaces have been linked with the greatest percentage of severe non-contact injuries.... Read more »
Wannop JW, Luo G, & Stefanyshyn DJ. (2013) Footwear traction and lower extremity noncontact injury. Medicine and Science in Sports and Exercise, 45(11), 2137-43. PMID: 23657169
Researchers from the University of Pennsylvania and Drexel University have experimentally shown that ferroelectric solar cells based on perovskite oxides can absorb three to six times more solar energy than the ones based on current ferroelectric materials, opening a road to inexpensive, easy to manufacture and efficient solar cells.... Read more »
Ilya Grinberg, D. Vincent West, Maria Torres, Gaoyang Gou, David M. Stein, Liyan Wu, Guannan Chen, Eric M. Gallo, Andrew R. Akbashev, Peter K. Davies, Jonathan E. Spanier, Andrew M. Rappe. (2013) Perovskite oxides for visible-light-absorbing ferroelectric and photovoltaic materials. Nature. DOI: 10.1038/nature12622
Researchers at Duke University’s Pratt School of Engineering have created an inexpensive material capable of harvesting energy from microwaves.... Read more »
Hawkes A.M., Katko A.R., & Cummer S.A. (2013) A microwave metamaterial with integrated power harvesting functionality. Applied Physics Letters. DOI: 10.1063/1.4824473
Window or aisle? Hamburger or hot dog? Bouquet of flowers or rotting flesh? Not all your preferences are up to you—some have been hammered into your genes by evolution.
If you're an average human, you avoid the smell of decay. It signals unsafe food and the threat of infection or disease. Other animals run toward the stench of a stale carcass, maybe because they're flies and it signals a place to lay their eggs.
Whether they love it or hate it, animals identify the scent of rot from two s........ Read more »
Ashiq Hussain, Luis R. Saraiva, David M. Ferrero, Gaurav Ahuja, Venkatesh S. Krishna, Stephen D. Liberles, & Sigrun I. Korsching. (2013) High-affinity olfactory receptor for the death-associated odor cadaverine. PNAS. DOI: 10.1073/pnas.1318596110
This will be the first in a series of posts on preterm birth. Preterm birth may not seem on the surface important in brain disorders.However, an increasing body of research is showing the importance of preterm birth in later development of childhood and adult brain disorders.An important contribution to this area of research is an Australian study using structured psychiatric assessment in a series of children at age seven who had been born prematurely.The key elements of this study design inclu........ Read more »
Treyvaud K, Ure A, Doyle LW, Lee KJ, Rogers CE, Kidokoro H, Inder TE, & Anderson PJ. (2013) Psychiatric outcomes at age seven for very preterm children: rates and predictors. Journal of child psychology and psychiatry, and allied disciplines, 54(7), 772-9. PMID: 23347471
The instructors themselves often refer to science to explain miracle cures and healing effects of hot yoga. As a scientist, I am reluctant to believe much of what is said. Is there really any truth in the 5 health claims or is it just all a marketing tool?... Read more »
Hunter SD, Dhindsa M, Cunningham E, Tarumi T, Alkatan M, & Tanaka H. (2013) Improvements in glucose tolerance with Bikram yoga in older obese adults: A pilot study. Journal of bodywork and movement therapies, 17(4), 404-7. PMID: 24138995
Tracy BL, & Hart CE. (2013) Bikram yoga training and physical fitness in healthy young adults. Journal of strength and conditioning research / National Strength , 27(3), 822-30. PMID: 22592178
Reynolds CJ, Cleaver BJ, & Finlay SE. (2012) Exercise associated hyponatraemia leading to tonic-clonic seizure. BMJ case reports. PMID: 22927272
Scientists, for the first time, found the neural mechanism of sensing high-speed motion in faint light in the visual cortex of the brain.
Neurons in the visual cortex:
A group of neurons in the primary visual cortex (V1) of the brain are luminance-contrast cells that are responsive to a uniform patch of luminance and they prefer low spatial frequencies, high temporal frequencies, high motion speeds, and they respond st........ Read more »
Ran Li, Yi Wang. (2013) Neural Mechanism for Sensing Fast Motion in Dim Light. Scientific Reports. DOI: 10.1038/srep03159
There's a scene in the 2013 comedy film The World's End in which a group of middle-aged old school friends are on a nostalgic pub crawl, yet one of them, Andy Knightly, insists on abstaining from alcohol. "I haven't had a drink for sixteen years Gary," he tells the ring-leader and lush Gary King. "You must be thirsty then," Gary retorts.
This social dynamic - the reluctant non-drinker coerced to join in with the drinking majority - will be familiar to many readers. And given the health risks ........ Read more »
Conroy D, & de Visser R. (2013) 'Man up!': Discursive constructions of non-drinkers among UK undergraduates. Journal of health psychology, 18(11), 1432-44. PMID: 23188922
The title of this post should also have included the word 'glutathione' too based on the results reported by Richard Frye and colleagues* (open-access) describing behavioural and biochemical data from a 3-month open trial of methylcobalamin, a vitamin B12 'vitamer', and folinic acid with a group of children diagnosed with an autism spectrum disorder (ASD).Dr Frye and his various research are no stranger to this blog; ranging from mitochondrial dysfunction linked to cases of autism (see here........ Read more »
Richard Frye, Stepan Melnyk, George Fuchs, Tyra Reid, Stefanie Jernigan, Oleksandra Pavliv, Amanda Hubanks, David W. Gaylor, Laura Walters, S. Jill James. (2013) Effectiveness of Methylcobalamin and Folinic Acid Treatment on Adaptive Behavior in Children with Autistic Disorder Is Related to Glutathione Redox Status. Autism Research and Treatment. DOI: 10.1155/2013/609705
Human beings have the strong and universal tendency to prefer immediate gains over longer-term rewards. New experiments show that exposure to nature reduces this future discounting.... Read more »
van der Wal AJ, Schade HM, Krabbendam L, & van Vugt M. (2013) Do natural landscapes reduce future discounting in humans?. Proceedings. Biological sciences / The Royal Society, 280(1773), 20132295. PMID: 24197412
Scientists have proposed that the primitive life forms on terrestrial planets can be ejected into space from where they would be carried to the other planets, and moons of the Jupiter and Saturn to generate life. This report is supporting the concept of lithopanspermia.
arXiv - accepted for publication in Astrobiology
In the present study, scientists performed simulations to find the places where the rocks and other small celestial bodies w........ Read more »
R. J. Worth, Steinn Sigurdsson, & Christopher H. House. (2013) Seeding Life on the Moons of the Outer Planets via Lithopanspermia. arXiv. arXiv: 1311.2558v1
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