MedicalResearch.com Interview with: Frank R. Noyes, M.D. President and Medical Director, Noyes Knee Institute and the Cincinnati Sports medicine Research and Education Foundation Cincinnati, Ohio MedicalResearch: What is the background for this study? Dr. Noyes: Meniscectomy, or removal of the … Continue reading →
The post About 50% of Meniscus Transplants Fail by Ten Years appeared first on MedicalResearch.com Medical Research Interviews and News.
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Frank R. Noyes, M.D. (2015) About 50% of Meniscus Transplants Fail by Ten Years. MedicalResearch.com. info:/
MedicalResearch.com Interview with: Prof. Abdel-Latif Mohamed Discipline of Neonatology, Medical School, College of Medicine, Biology & Environment Australian National University Acton, Canberra, ACT, Australia Medical Research: What is the background for this study? What are the main findings? Prof. Mohamed: Despite … Continue reading →
The post Treatment of Patent Ductus Arteriosus Linked to Neurodevelopmental Risks in Infants appeared first on MedicalResearch.com Medical Rese........ Read more »
Prof. Abdel-Latif Mohamed. (2015) Treatment of Patent Ductus Arteriosus Linked to Neurodevelopmental Risks in Infants. MedicalResearch.com. info:/
"The minority of the AS [Asperger syndrome] group who no longer met criteria for a full diagnosis of an autism spectrum disorder were usually free of current psychiatric comorbidity."That was one of the details reported by I. Carina Gillberg and colleagues  continuing their longitudinal look at a group of males diagnosed with Asperger syndrome and participants' experiences as a function of their presented symptoms and risk of other comorbidity.Titled 'Boys with Asperger Sy........ Read more »
Gillberg IC, Helles A, Billstedt E, & Gillberg C. (2015) Boys with Asperger Syndrome Grow Up: Psychiatric and Neurodevelopmental Disorders 20 Years After Initial Diagnosis. Journal of autism and developmental disorders. PMID: 26210519
When the right gene is expressed in the right manner in the right population of stem cells, the developing mouse brain can exhibit primate-like features. Researchers at the Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG) succeeded in mimicking the sustained expression of the transcription factor Pax6 as seen in the developing human brain, in mouse cortical progenitor cells. This altered the behavior of these cells to one that is akin to that of progenitors in the developing........ Read more »
Fong Kuan Wong, Ji-Feng Fei, Felipe Mora-Bermúdez, Elena Taverna, Christiane Haffner, Jun Fu, Konstantinos Anastassiadis, A. Francis Stewart, & Wieland B. Huttner. (2015) Sustained Pax6 Expression Generates Primate-like Basal Radial Glia in Developing Mouse Neocortex. PLOS Biology. info:/10.1371/journal.pbio.1002217
In an effort to build better bodies, more men are turning not to illegal anabolic steroids, but to legal over-the-counter bodybuilding supplements to the point where it may qualify as an emerging eating disorder, according to research presented at the American Psychological Association’s annual convention.... Read more »
Richard Achiro et al. (2015) Excessive Workout Supplement Use: An Emerging Eating Disorder in Men. American Psychological Association. info:/Other
Marathon runners are on the road for hours at a time, what on earth goes through their minds all that time? Past investigations have relied on asking runners to remember what they were thinking about, but of course that is an unreliable method. Now Ashley Samson and her team have conducted the first ever "think aloud" investigation of long-distance runners, which involves them verbalising "everything that passes through your head", so that their thoughts can be recorded and analysed. The researc........ Read more »
Samson, A., Simpson, D., Kamphoff, C., & Langlier, A. (2015) Think aloud: An examination of distance runners’ thought processes. International Journal of Sport and Exercise Psychology, 1-14. DOI: 10.1080/1612197X.2015.1069877
MedicalResearch.com Interview with: Candida J. Rebello and Dr. Frank Greenway Pennington Biomedical Research Center Baton Rouge, Louisiana MedicalResearch: What is the background for this study? What are the main findings? Response: Appethyl™ contains concentrated thylakoid membranes extracted from spinach leaves. … Continue reading →
The post Spinach Extract May Reduce Hunger and Caloric Intake appeared first on MedicalResearch.com Medical Research Interviews and News.
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Candida J. Rebello and Dr. Frank Greenway. (2015) Spinach Extract May Reduce Hunger and Caloric Intake. MedicalResearch.com. info:/
Vibram FiveFingers and muscle strength … umm, err…... Read more »
Campitelli, N., Bernhard, K., Kidon, A., Heard, K., Spencer, S., & Kawalec, J. (2015) Effect of Vibram FiveFingers Minimalist Shoes on the Abductor Hallucis Muscle. Journal of the American Podiatric Medical Association, 2147483647. DOI: 10.7547/14-084.1
You know that feeling when you're halfway through a sentence and can't think of the next word you need? It's a word you know, but you can't quite bring it to mind. There's a name for that phenomenon...what is it, again?
Oh right, the "tip of the tongue."
Everyday failures in our speech, like forgetting a word or saying the wrong one, are great fodder for scientists who want to understand language. But they're hard to study in the lab, because you can't force someone to make a mistake. ... Read more »
Michael S. Vitevitch. (2015) Speech error and tip-of-the-tongue diary for mobile devices. Frontiers in Psychology. info:/10.3389/fpsyg.2015.01190
Another day, another alarming brain-related story hits the news:
Dementia is striking victims earlier and death rates are soaring
Modern living has led to earlier dementia, says study
In fact the study in question doesn't show that. The paper, published in Surgical Neurological International (see also) is from British researchers Colin Pritchard and Emily Rosenorn-Lanng.
The authors show that the number of deaths attributed to neurological diseases (including dementia) have risen ... Read more »
Pritchard, C., & Rosenorn-Lanng, E. (2015) Neurological deaths of American adults (55-74) and the over 75′s by sex compared with 20 Western countries 1989-2010: Cause for concern. Surgical Neurology International, 6(1), 123. DOI: 10.4103/2152-7806.161420
MedicalResearch.com Interview with: Edward W. Cowen, MD, MHSc Dermatology Branch, Center for Cancer Research National Cancer Institute Bethesda, Maryland Medical Research: What is the background for this study? Dr. Cowen: Cutaneous leiomyomas are benign smooth muscle proliferations that are associated with pain … Continue reading →
The post Botulinum Toxin Reduces Pain of Skin Leiomyomas appeared first on MedicalResearch.com Medical Research Interviews and News.
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Edward W. Cowen, MD, MHSc. (2015) Botulinum Toxin Reduces Pain of Skin Leiomyomas. MedicalResearch.com. info:/
Synthetic lethal compounds selectively kill cancer cells by targeting tumour cell-essential processes, but leave healthy cells unharmed. Research is ongoing to identify such compounds in a range of cancers (reviewed in McLornan et al., 2014) including renal cell carcinoma (RCC). New research from Wolff et al., (2015) has identified homoharringtonine (HHT) as synthetically lethal for a subset of clear cell RCC (ccRCC) tumours associated with VHL mutations.... Read more »
Wolff NC, Pavía-Jiménez A, Tcheuyap VT, Alexander S, Vishwanath M, Christie A, Xie XJ, Williams NS, Kapur P, Posner B.... (2015) High-throughput simultaneous screen and counterscreen identifies homoharringtonine as synthetic lethal with von Hippel-Lindau loss in renal cell carcinoma. Oncotarget, 6(19), 16951-62. PMID: 26219258
MedicalResearch.com Interview with: Matthew D. Krasowski MD, PhD Department of Pathology University of Iowa, Iowa City, and Jonathan Genzen, MD, PhD Department of Pathology University of Utah, Salt Lake City, UT Medical Research: What is the background for this study? … Continue reading →
The post ACE Level Lowered by ACE Inhibitors Can Falsely Rule Out Sarcoidosis appeared first on MedicalResearch.com Medical Research Interviews and News.
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Matthew D. Krasowski MD, PhD and Jonathan Genzen, MD, PhD. (2015) ACE Level Lowered by ACE Inhibitors Can Falsely Rule Out Sarcoidosis. MedicalResearch.com. info:/
MedicalResearch.com Interview with: Jane Marjoribanks Obstetrics and Gynaecology University of Auckland, National Women’s Hospital, Auckland, New Zealand MedicalResearch: What is the background for this study? Response: This study is a systematic review of all randomised evidence published up to January … Continue reading →
The post NSAIDS Work For Menses Pain But Carry Risk of Side Effects appeared first on MedicalResearch.com Medical Research Interviews and News.
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Jane Marjoribanks. (2015) NSAIDS Work For Menses Pain But Carry Risk of Side Effects. MedicalResearch.com. info:/
Right now I’m working on the historical background to my dissertation, which means reading a lot of historical texts and history books on early medieval England. As an archaeologist, I’ve […]... Read more »
Constantinescu, M., Gavrilă, E., Greer, S., Soficaru, A., & Ungureanu, D. (2015) Fighting to the Death: Weapon Injuries in a Mass Grave (16th-17th Century) from Bucharest, Romania. International Journal of Osteoarchaeology. DOI: 10.1002/oa.2450
MedicalResearch.com Interview with: Paul Little MBBS, BA, MD, DLSHTM, MRCP, FRCGP, FMedSci Professor of Primary Care Research University of Southampton Medical Research: What is the background for this study? What are the main findings? Prof. Little: Hand washing has been … Continue reading →
The post Simple Internet Program Increased Handwashing and Reduced Infections appeared first on MedicalResearch.com Medical Research Interviews and News.
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Paul Little MBBS, BA, MD. (2015) Simple Internet Program Increased Handwashing and Reduced Infections. MedicalResearch.com. info:/
Pulse trains to percepts: the challenge of creating a perceptually intelligible world with sight recovery technologies.... Read more »
Fine I, & Boynton GM. (2015) Pulse trains to percepts: the challenge of creating a perceptually intelligible world with sight recovery technologies. Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 370(1677). PMID: 26240423
A quick post for your consumption today based on the findings reported by Maria Jalbrzikowski and colleagues  (open-access available here) who undertook "genomic analyses of 22q11DS to identify genes and pathways related to specific phenotypes." 22q11DS - 22q11.2 Deletion Syndrome - is a genetic condition characterised by a deletion of a small piece of genetic material of chromosome 22. Autism is among several presentations that can co-occur in cases of 22q11DS (sometimes called Del........ Read more »
Jalbrzikowski M, Lazaro MT, Gao F, Huang A, Chow C, Geschwind DH, Coppola G, & Bearden CE. (2015) Transcriptome Profiling of Peripheral Blood in 22q11.2 Deletion Syndrome Reveals Functional Pathways Related to Psychosis and Autism Spectrum Disorder. PloS one, 10(7). PMID: 26201030
Researchers at USC have developed a yeast model to study a gene mutation that disrupts the duplication of DNA, causing massive damage to a cell’s chromosomes, while somehow allowing the cell to continue dividing. The result is a mess: Zombie cells that by all rights shouldn’t be able to survive, let alone divide, with their […]... Read more »
Sabatinos, S., Ranatunga, N., Yuan, J., Green, M., & Forsburg, S. (2015) Replication stress in early S phase generates apparent micronuclei and chromosome rearrangement in fission yeast. Molecular Biology of the Cell. DOI: 10.1091/mbc.E15-05-0318
Many fungi and oomycetes (fungus-like microbes often called water moulds) like to eat plants. Unfortunately for us, these plants include basically all of the ones we grow for food. Thus another front of the human-microbe war rages ever onward. In an effort to gain an edge against our dastardly eukaryotic cousins, scientists have compiled a whole lot of data on how plant-eating fungi and oomycetes go about their business. To grow these microorganisms in the laboratory, researchers have taken the ........ Read more »
Galkiewicz, J., Stellick, S., Gray, M., & Kellogg, C. (2012) Cultured fungal associates from the deep-sea coral Lophelia pertusa. Deep Sea Research Part I: Oceanographic Research Papers, 12-20. DOI: 10.1016/j.dsr.2012.05.001
Kent CR, Ortiz-Bermúdez P, Giles SS, & Hull CM. (2008) Formulation of a defined V8 medium for induction of sexual development of Cryptococcus neoformans. Applied and Environmental Microbiology, 74(20), 6248-53. PMID: 18776031
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