Post List

  • April 16, 2010
  • 09:02 PM

How to Deliver New Enzymes to Clean Up Aged Cells

by Reason in Fight Aging!

Medical bioremediation is the name given to the SENS Foundation approach to removing one class of harmful waste chemicals that accumulate in our cells with advancing age: Cells have a lot of reasons to break down big molecules and structures into their component parts, and a lot of ways to do so. Unfortunately, one of the main reasons to break things down is because they have been chemically modified so that they no longer work, and sometimes these chemical modifications create structures that a........ Read more »

  • April 16, 2010
  • 05:22 PM

On the Loose

by Journal Watch Online in Journal Watch Online

Non-native species could escape from Spanish zoos

... Read more »

  • April 16, 2010
  • 04:58 PM

Don't t-a-a-a-a-a-a-aze me bro!

by DrugMonkey in DrugMonkey

sourceA report in Popular Science (authored by Jeremy Hsu) points to a recent paper published in Academic Emergency Medicine. In this, Dawes and colleagues report on an investigation on the effects of TASER on sheep intoxicated with methamphetamine (MA). I was alerted to this by Damn Good Technician who wanted a little bit of context for what would seem to be a WTF? kind of study.

The study was conducted in Dorset sheep who were anesthetized, and administered 0, 0.5, 1.0 or 1.5 mg/kg of metha........ Read more »

Dawes DM, Ho JD, Cole JB, Reardon RF, Lundin EJ, Terwey KS, Falvey DG, & Miner JR. (2010) Effect of an electronic control device exposure on a methamphetamine-intoxicated animal model. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 17(4), 436-43. PMID: 20370784  

  • April 16, 2010
  • 02:00 PM

How to choose a good profile picture

by eHarmony Labs in eHarmony Labs Blog

Recent research may help you decide on the best photo to post. Learn more. ... Read more »

  • April 16, 2010
  • 11:23 AM

Managing Multiple Myeloma: turning an acute cancer into a chronic disease

by Sally Church in Pharma Strategy Blog

The other day while travelling home on a long train journey, I was browsing the NY Times app on my iPhone and came across an interesting story about multiple myeloma in the Health section: "For many patients with cancers like...... Read more »

  • April 16, 2010
  • 05:00 AM

Bees and butterflies in Harlem: increasing pollinator diversity in urban areas

by Rob Goldstein in Conservation Maven

... Read more »

  • April 16, 2010
  • 05:00 AM

Mad Mice

by Kevin Mitchell in Wiring the Brain

The mighty mouse has become an invaluable tool in biomedical research, due to the fact that its genome can readily be manipulated, using genetic engineering techniques in embryonic stem cells.  These techniques were first developed to “knock out” or delete any gene in the mouse genome and this approach is so established now that off-the-shelf knockouts for most genes in the genome are already available from several centres.  Genetic technologies have become increasingly sophisticated, givi........ Read more »

  • April 16, 2010
  • 03:38 AM

Active case-finding to improve tuberculosis control.

by Bernt Lindtjorn in International Health Research

Is active case finding necessary to control tuberculosis in developing countries?
Tuberculosis is one of the world’s leading causes of death and disease. Despite effective treatment, tuberculosis still results in several million deaths each year. Reducing the burden of global TB disease is a part the Millennium Development Goals. Earlier, health authorities thought that DOTS (Direct [...]... Read more »

  • April 16, 2010
  • 03:00 AM

Study links cancer mortality rates with ecological integrity of streams

by Rob Goldstein in Conservation Maven

A new study from West Virginia finds a significant relationship between the cancer mortality rates in local communities and the ecological integrity of nearby streams. Evidence suggests that coal mining is the underlying cause of both problems. This shows that measurements of stream ecological integrity can serve as a warning sign of underlying environmental problems that are causing cancer in local populations...... Read more »

  • April 16, 2010
  • 02:02 AM

Friday Weird Science: Smells Fishy? Check your semen.

by Evil Monkey in Neurotopia

Sometimes, Sci is simply inundated with weird science opportunities, and such a week is this one. There is SO MUCH WEIRD OUT THERE, you guys. This is great, as it keeps Friday Weird Science in business, but sometimes Sci has to file away so many for later that she loses track. Here's really hoping that she WON'T lose track, because she found some real beauties today. And this was one of the best one.

In response to a question from awesome reader and friend of the blog Pascale: Can I post on........ Read more »

Chvapil, M., Chvapil, T., & Eskelson, C. (1978) Studies on vaginal malodor. Archiv f�r Gyn�kologie, 225(2), 77-89. DOI: 10.1007/BF00670844  

  • April 15, 2010
  • 08:44 PM

Fire and Ice

by teofilo in Gambler's House

Most research on human-environment interactions focuses on large-scale changes in environmental conditions over long periods of time (by human standards, at least).  There are good reasons for this, especially when applied to prehistory, most importantly that there are a lot of potential data sources for environmental conditions that can be correlated with cultural chronologies to [...]... Read more »

Elson, M., Ort, M., Hesse, S., & Duffield, W. (2002) Lava, Corn, and Ritual in the Northern Southwest. American Antiquity, 67(1), 119. DOI: 10.2307/2694881  

  • April 15, 2010
  • 07:59 PM

I get e-mail too!

by Kristopher Hite in Tom Paine's Ghost

T. G. Dobzhansky, a prominant evolutionary biologist once said...

"Nothing in biology makes sense except in the light of evolution" 

Recently, I received a request from a Tom Paine's Ghost reader to answer some questions about public perceptions of evolution. The questions, along with my responses follow.

Reader: How is evolution relevant to the lives of everyday people?

TPG: I will here talk about medicine, childhood obesity, and sex.

The first topic that springs to mind when I think ........ Read more »

  • April 15, 2010
  • 06:30 PM

Prey populations explode as predators get smaller

by Daniel Bassett in Chew the Fat

When top predators are removed from ecosystems their prey and/or competitors increase due to decreased predation and competitive release. However, can changes in behaviour, or body size, of the predators also cause this effect?... Read more »

Shackell, N., Frank, K., Fisher, J., Petrie, B., & Leggett, W. (2009) Decline in top predator body size and changing climate alter trophic structure in an oceanic ecosystem. Proceedings of the Royal Society B: Biological Sciences, 277(1686), 1353-1360. DOI: 10.1098/rspb.2009.1020  

  • April 15, 2010
  • 06:04 PM

Can Our Fantasy Life Affect Our Perceptions of Real Life?

by Darcy Cowan in Skepticon

Recently there’s been a television promotional advertisement that really bugs me. It shows a man watching events appearing before his eyes and has a voice-over that says something to the effect of “When you look back on your life are you going to see a life filled with interesting people and excitement?” and when is [...]... Read more »

  • April 15, 2010
  • 06:01 PM

Not all risk is risk

by Jan Husdal in

The article lists and discusses eight risk definitions, and then suggests an alternative and comprehensive definition that captures all aspects of [ ... ]... Read more »

  • April 15, 2010
  • 05:00 PM

When the pain of carpal tunnel syndrome spreads, we should be thinking dorsal horn not malingering

by Lorimer Moseley in BodyInMind

Here is an important study.  A couple of Italian Neurologists have investigated people with carpal tunnel syndrome who report that their pain has spread beyond the boundaries of the median nerve.  Unfortunately, such reports are often misinterpreted by clinicians as evidence of malingering, or hysteria.  Well, these fellows did quantitative sensory testing and came up [...]... Read more »

[1] Caliandro P, La Torre G, Aprile I, Pazzaglia C, Commodari I, Tonali P, & Padua L. (2006) Distribution of paresthesias in Carpal Tunnel Syndrome reflects the degree of nerve damage at wrist. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 117(1), 228-31. PMID: 16325467  

[3] Treede RD, Jensen TS, Campbell JN, Cruccu G, Dostrovsky JO, Griffin JW, Hansson P, Hughes R, Nurmikko T, & Serra J. (2008) Neuropathic pain: redefinition and a grading system for clinical and research purposes. Neurology, 70(18), 1630-5. PMID: 18003941  

[4] Wilder-Smith EP, Ng ES, Chan YH, & Therimadasamy AK. (2008) Sensory distribution indicates severity of median nerve damage in carpal tunnel syndrome. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 119(7), 1619-25. PMID: 18467170  

  • April 15, 2010
  • 04:20 PM

New developments in castration resistant prostate cancer - MDV3100

by Sally Church in Pharma Strategy Blog

Last night I received an alert from Medivation announcing that an article would be published in today's online The Lancet regarding their prostate cancer agent, MDV3100. Sure enough, here's the article: Although the trial is an early phase I/II study,...... Read more »

Scher, H., Beer, T., Higano, C., Anand, A., Taplin, M., Efstathiou, E., Rathkopf, D., Shelkey, J., Yu, E., & Alumkal, J. (2010) Antitumour activity of MDV3100 in castration-resistant prostate cancer: a phase 1–2 study. The Lancet. DOI: 10.1016/S0140-6736(10)60172-9  

  • April 15, 2010
  • 04:00 PM

A Lesson Before Dying

by Journal Watch Online in Journal Watch Online

Scientists train endangered carnivores to avoid poisonous toads

... Read more »

  • April 15, 2010
  • 02:14 PM

Field Talk: Termites enrich the soil in East Africa

by Katie Kline in EcoTone

Vertebrate fertilizer is not the only source of nutrients in the soils of East African savannahs, at least according to a study recently published in the journal Ecology. Alison Brody from the University of Vermont and colleagues found that termites actually had more of an effect on the fruiting success of Acacia trees in Kenya than did dung and urine deposition from ungulate herbivores, such as zebras and gazelles.

... Read more »

  • April 15, 2010
  • 01:44 PM

Fossil Shell Preserves Signs of a Prehistoric Tug-of-War

by Laelaps in Laelaps

Top of the encrusted surface of a brachiopod shell, showing the "war" between an edrioasteroid (star-shaped organism at center) and a fast-growing bryozoan colony. From Sprinkle and Rodgers 2010.

Back in the early days of paleontology, when the meaning and origin of fossils was still in doubt, some naturalists believed that the shells, shark teeth, and other petrified curiosities were attempts by the rock to imitate life. Fossils were not true vestiges of history, it was believed, but inst........ Read more »

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