Post List

  • November 18, 2009
  • 10:11 AM

Motility of Cancer Cells

by Lab Rat in Lab Rat

Cancer is a disease of multicellular organisms. In order to become multicellular, a certain amount of control needs to be exerted over each individual cell, cells can no longer move around, grow, and divide when they want too. Instead they must obey signals from the surrounding environment (including their fellow cells) which tell them what to do. Cancer, like anarchy, is what happens when the control breaks down, and individual cells start growing and dividing regardless.Uncontrolled growth lea........ Read more »

SAHAI, E. (2005) Mechanisms of cancer cell invasion. Current Opinion in Genetics , 15(1), 87-96. DOI: 10.1016/j.gde.2004.12.002  

  • November 18, 2009
  • 09:52 AM

Genes-Environment interactions in predicting adolescent depression: Effects of sex and stress type.

by Nestor Lopez-Duran PhD in Child-Psych

Many of you have probably heard that studies have identified specific gene variations that when interacting with stressors in the environment increase the risk of developing depression. This interaction has been used by researchers and clinicians to explain why some people become depressed when exposed to stressful events, while others appear resilient. The argument is [...]... Read more »

  • November 18, 2009
  • 09:22 AM

One Pill Makes Your Libido Larger

by Neuroskeptic in Neuroskeptic

It's every man's dream - a pill to make women want more sex. According to Boehringer Pharmaceuticals, that dream could be a reality in a few years, in the form of the strangely-named flibanserin. But is it the latest wonder-drug or just a glorified sleeping pill? Read on.Flibanserin was originally developed as an antidepressant, but in clinical trials against depression it reportedly failed to perform better than placebo. The standard for getting approved as an antidepressant is low, s........ Read more »

Borsini F, Evans K, Jason K, Rohde F, Alexander B, & Pollentier S. (2002) Pharmacology of flibanserin. CNS drug reviews, 8(2), 117-42. PMID: 12177684  

  • November 18, 2009
  • 08:47 AM

A New Look at Medical Errors in Residency Training

by Shaheen Lakhan in Brain Blogger

It’s a phenomenon that medical educators have long suspected but haven’t been able to prove: a rise in medical errors when newly-hatched physicians begin their residency training programs in July. This suspected occurrence has been studied several times, but until recently, no conclusive evidence existed that it actually was true. For the first time, a [...]... Read more »

  • November 18, 2009
  • 08:00 AM

The impacts of wild horses on a desert ecosystem

by Rob Goldstein in Conservation Maven

Bands of wild horses roaming the remote deserts of the southwestern United States conjure up an iconic image in many people's minds. But for conservationists, the introduced equines have fueled controversy over their impacts to desert ecosystems.... Read more »

Ostermann-Kelm, S., Atwill, E., Rubin, E., Hendrickson, L., & Boyce, W. (2009) Impacts of feral horses on a desert environment. BMC Ecology, 9(1), 22. DOI: 10.1186/1472-6785-9-22  

  • November 18, 2009
  • 08:00 AM

Internet against government corruption

by David Bradley in Sciencetext

Can the internet prevent government corruption? You’re probably never going to meet an entirely honest politician, but according to a statistical study by US researchers of 170 countries the internet could provide the tools necessary to reduce corruption significantly.
Martha García-Murillo of the School of Information Studies, at Syracuse University, New York, modeled political, economic and [...]Post from: David Bradley's Sciencetext Tech TalkInternet against government corruption
... Read more »

Martha García-Murillo. (2010) The effect of internet access on government corruption. Electronic Government, An International Journal, 7(1), 22-40. info:/

  • November 18, 2009
  • 07:46 AM

Tracking the Niche, A Project of Grinnellian Proportions

by Johnny in Ecographica

Grinnell’s philosophy of scientific inquiry focused intently on the task of accumulating as much raw data as possible. For example, during the biological survey he carried out in Yosemite National Park between the years 1914 and 1920, Grinnell and his field crews collected 817 photographs, nearly 3000 animal specimens and more than 2000 pages of notes! Being organized and detail oriented is one thing, but Grinnell’s drive for thoroughness approached the obsessive.
... Read more »

  • November 18, 2009
  • 06:00 AM

Viruses and journalism: Off-the-shelf chemicals

by Vincent Racaniello in virology blog

I have had many opportunities to speak with journalists of different kinds during the more than 30 years that I have studied viruses. I wrote previously about my negative experience with CNN. I’d like to relate a much more positive encounter with newspaper reporters.
As a postdoctoral fellow in David Baltimore’s laboratory I was fortunate to [...]... Read more »

  • November 18, 2009
  • 05:30 AM

How infants affect how much their carers engage with them

by Christian Jarrett in BPS Research Digest

Young children benefit socially and intellectually the more their carers engage and respond to them. Recognising this, we can train nursery staff to be as responsive to the children in their care as possible. But a new study by Claire Vallotton raises an interesting and under-examined issue - what if there's something about some infants that leads their carers to engage with them more, thus giving them an advantage over their peers.Vallotton filmed interactions between 18 student caregivers and ........ Read more »

  • November 18, 2009
  • 04:31 AM

Good News/Bad News Update on Nucleus Accumbens DBS for Treatment-Resistant Depression

by The Neurocritic in The Neurocritic

Taken from Fig. 1 (Bewernick et al., 2009). Hamilton Depression Rating Scale (PDF) over time.Two and a half years ago, The Neurocritic wrote about the very early results of deep brain stimulation (DBS) in the nucleus accumbens for severe, refractory depression. You can read about the details of the procedure and its scientific motivation here:More About the Nucleus AccumbensNAcc Localization for DBSBriefly, the nucleus accumbens (NAcc) is considered one of the brain's PLEASURE CENTRES:When the ........ Read more »

Bewernick, B., Hurlemann, R., Matusch, A., Kayser, S., Grubert, C., Hadrysiewicz, B., Axmacher, N., Lemke, M., Cooper-Mahkorn, D., & Cohen, M. (2009) Nucleus Accumbens Deep Brain Stimulation Decreases Ratings of Depression and Anxiety in Treatment-Resistant Depression. Biological Psychiatry. DOI: 10.1016/j.biopsych.2009.09.013  

  • November 18, 2009
  • 04:12 AM

Publication bias in clinical trials

by Martin Fenner in Gobbledygook @ Nature Network

Selective outcome reporting in clinical trials about off-label uses for gabapentin.... Read more »

Vedula, S., Bero, L., Scherer, R., & Dickersin, K. (2009) Outcome Reporting in Industry-Sponsored Trials of Gabapentin for Off-Label Use. New England Journal of Medicine, 361(20), 1963-1971. DOI: 10.1056/NEJMsa0906126  

  • November 18, 2009
  • 03:11 AM

Self Diagnosis in General Practice

by Dr Shock in Dr Shock MD PhD

With the Internet many patients visit the GP after extensive searches on the Internet. They usually have an idea about what’s wrong with them. In a recent publication in the British Medical Journal I found a recent article on this subject. In visits to a GP patients the self diagnosis (also called self labelling) was [...]

Related posts:Depression in General Practice In the recent numbers of British Journal of General...Predictors of nonadherence to antidepressants in depressed patient........ Read more »

Goyder, C., McPherson, A., & Glasziou, P. (2009) Self diagnosis. BMJ, 339(nov11 1). DOI: 10.1136/bmj.b4418  

  • November 18, 2009
  • 12:58 AM

A New Kind of Supernova?

by Jon Voisey in Angry Astronomer

In general, supernova come in two flavors: The core collapse Type II supernovae, and the white dwarf over the Chandrasekhar limit, Type II supernova. The two are distinguished by the elemental composition of their spectra: Type II stars still have a hydrogen envelope and thus, hydrogen lines are prominent. Type I supernova, being the burned out cores of stars, don't have that envelope, so heavier elements, like silicon are present.However, the Supernova 2002bj defies classification. Initially, i........ Read more »

Poznanski, D., Chornock, R., Nugent, P., Bloom, J., Filippenko, A., Ganeshalingam, M., Leonard, D., Li, W., & Thomas, R. (2009) An Unusually Fast-Evolving Supernova. Science. DOI: 10.1126/science.1181709  

  • November 18, 2009
  • 12:35 AM

Exercise Prevents Regain of Visceral Fat (But Not Body Weight)

by Travis Saunders, MSc in Obesity Panacea

Peter and I have often discussed the links between visceral fat and metabolic risk. Visceral fat is the fat which surrounds the internal organs, and is thought to mediate much of the risk between obesity and disease. For example, individuals with excess body weight tend to have more visceral fat, which is likely responsible for the relationship between body weight and numerous chronic diseases. However, as Peter discussed on Monday, subcutaneous fat (the fat beneath the skin) does not seem to........ Read more »

  • November 18, 2009
  • 12:27 AM

Thanks, Charles

by Journal Watch Online in Journal Watch Online

Darwin’s specimens aid efforts to save Galapagos mockingbird

... Read more »

Hoeck, P., Beaumont, M., James, K., Grant, R., Grant, P., & Keller, L. (2009) Saving Darwin's muse: evolutionary genetics for the recovery of the Floreana mockingbird. Biology Letters. info:/10.1098/rsbl.2009.0778

  • November 17, 2009
  • 11:51 PM

The evolutionary origins of religion

by David Basanta in Cancerevo: Cancer evolution

Science continues with a series of essays commemorating the year of Darwin. This week (and by this week I mean the one I got this week, actually dated 6th of November) the topic is the evolutionary origins of religion.

This is quite an interesting topic to which I was first introduced with Daniel Dennett’s Breaking the spell: religion as a natural phenomenom. The central premise is that there could be evolutionary advantages to communities in which individuals follow ways of thi........ Read more »

Culotta, E. (2009) On the Origin of Religion. Science, 326(5954), 784-787. DOI: 10.1126/science.326_784  

  • November 17, 2009
  • 09:20 PM

Towards Practical Intracellular Imaging without Fluorescence

by Michael Long in Phased

Ning Fang (Iowa State University) and coworkers have combined the imaging capabilities of differential interference contrast microscopy with the optical properties of metal nanoparticles to develop a supplement to fluorescence imaging. This news feature was written on November 17, 2009.... Read more »

  • November 17, 2009
  • 07:03 PM

M cells, gatekeepers or gateway to the gut

by geekheartsscience in geek!

Glycoprotein 2 is the M cell receptor for type I pili on bacteria and is important for the immune response to these bacteria, according to research by Hase and colleagues published last week in the journal Nature.
The mucosal immune system is one of the largest components of our immune system and is hugely important for [...]... Read more »

Hase, K., Kawano, K., Nochi, T., Pontes, G., Fukuda, S., Ebisawa, M., Kadokura, K., Tobe, T., Fujimura, Y., Kawano, S.... (2009) Uptake through glycoprotein 2 of FimH bacteria by M cells initiates mucosal immune response. Nature, 462(7270), 226-230. DOI: 10.1038/nature08529  

  • November 17, 2009
  • 05:28 PM

Men often treat their friends better than women do

by Dave Munger in Cognitive Daily

Who's more "sociable," men or women? Common sense says it's women, right? And many research studies back this impression up: Women are more interpersonal, more connected, more interdependent than men. Women are more likely to share intimate information with each other than men. But is that really the whole story?

There is also research suggesting that men have larger social networks than women do, and that male-male friendships last longer than female-female ones.

A team led by Joyce Benenson ........ Read more »

Benenson, J., Markovits, H., Fitzgerald, C., Geoffroy, D., Flemming, J., Kahlenberg, S., & Wrangham, R. (2009) Males' Greater Tolerance of Same-Sex Peers. Psychological Science, 20(2), 184-190. DOI: 10.1111/j.1467-9280.2009.02269.x  

  • November 17, 2009
  • 02:55 PM

The Brain Can Change Itself: Evidence From Impossible Phantom Limb Movements

by Daniel Hawes in Ingenious Monkey | 20-two-5

Fascinating research - often involving phantom limbs and smart sensory manipulations, -has shown that the brain’s body image relies heavily on learning via sensory feedback. This study shows the brain capable of reconstructing body image even in the absence of sensory feedback...... Read more »

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