Post List

  • March 27, 2010
  • 01:00 PM

Dormant viruses can hide in our DNA and be passed from parent to child

by Ed Yong in Not Exactly Rocket Science

During our early childhoods, the vast majority of us are boarded by a stowaway that can stay with us for the rest of our lives. It can rear its head when we are at our weakest and it can wriggle its way down our family tree into our children and grandchildren. It’s a virus called [...]... Read more »

Arbuckle, J., Medveczky, M., Luka, J., Hadley, S., Luegmayr, A., Ablashi, D., Lund, T., Tolar, J., De Meirleir, K., Montoya, J.... (2010) The latent human herpesvirus-6A genome specifically integrates in telomeres of human chromosomes in vivo and in vitro. Proceedings of the National Academy of Sciences, 107(12), 5563-5568. DOI: 10.1073/pnas.0913586107  

  • March 27, 2010
  • 08:00 AM

Screening for Postpartum Depression Not Worth the Time or Money

by Shaheen Lakhan in Brain Blogger

More than 10% of women experience either major or minor depression six weeks after giving birth. Postpartum depression (PPD) leads to significant biological, social, psychological, and economic consequences for the mother, the child, and the family. Clinically and cost-effective treatments are available for PPD, but less than half of PPD cases are ever diagnosed. Unfortunately, [...]... Read more »

  • March 27, 2010
  • 05:59 AM

Ménage à trois – the good, the bad and the ugly

by Jan Husdal in

No, it’s not what you perhaps think it is...hidden affairs and luscious constellations in the supply chain. Well, maybe it is, depending on your point of view. What it technically speaking is about, in boring laymen terms is this: The 9 archetypes of buyer-supplier-relationships in triads. ... Read more »

  • March 27, 2010
  • 02:57 AM

a new, smarter weapon against cancer cells?

by Greg Fish in weird things

They sneak in, find and neutralize their target with a complex biological weapon, then sneak out before they’re even detected. No, they’re not a special forces squad from a spy novel. They’re actually 70 nanometer particles which could become one of the most important weapons in fighting cancers if their promise is proven in large [...]... Read more »

Davis, M., Zuckerman, J., Choi, C., Seligson, D., Tolcher, A., Alabi, C., Yen, Y., Heidel, J., & Ribas, A. (2010) Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles. Nature. DOI: 10.1038/nature08956  

  • March 27, 2010
  • 02:11 AM

The factor structure of virtues and perosnality: a continuing mess

by sandygautam in The Mouse Trap

Image via Wikipedia

Continuing my theme of focusing on human character strengths and virtues and relating them to personality,  I have been doing more reading of the literature and want to discuss three papers today.
First up is Shyrack et al’s recent paper that again explores the factor structure of VIA-IS and finds support for a 3 More >Rating: 0.0/10 (0 votes cast)

Related posts:Character strengths and virtues: a 5/8 factor structure? Image via Wikipedia Positive psychol........ Read more »

  • March 26, 2010
  • 05:49 PM

Avoiding common errors in epidemiology

by C. Julian in The Swarm

All sciences make mistakes, and epidemiology is no exception. Raj Bhopal has chosen 7 illustrative mistakes and derived 7 solutions to avoid them. The mistakes (Roman numerals denoting solutions) are:
1. Failing to provide the context and definitions of study populations. (I State the location and timing of fieldwork and describe the study population in detail, especially age, sex, socio-economic... Read more »

  • March 26, 2010
  • 04:14 PM

Character strengths and virtues: a 5/8 factor structure?

by sandygautam in The Mouse Trap

Image via Wikipedia

Positive psychology is based on the premise that it is equally important to study what is good in life as it is to study what goes wrong. Positive psychology thus focuses on building and capitalizing on existing strengths of people while not focusing too much on their weaknesses, which has been focus More >Rating: 0.0/10 (0 votes cast)

Related posts:The factor structure of Religiosity and its neural substrates A new article in PNAS by Grafman et al, argues...
C........ Read more »

  • March 26, 2010
  • 04:09 PM

How Shoes Can Change Your Life - And Your Skeleton

by Isabelle Winder in Going Ape

A cross-section of a foot inside a shoe. Taken by Mattes, and downloaded from the Wikimedia Commons 26/03/2010.You might think that shoes can only change your life if you are a sex-and-the-city type shoe lover, spending huge amounts of money on designer footwear. And for most of us, that kind of dedication to shoes is fairly incomprehensible - after all, they're just things to wear to keep your feet safe from broken glass and tarmac, right? Wrong....In fact, footwear doesn't just change your lif........ Read more »

  • March 26, 2010
  • 03:57 PM

UPDATE : Bi-Directional Optogenetic Control

by AndrewHires in Brain Windows

The Deissseroth lab has released an updated version of their optical neuronal silencing gene Natronomonas halorhodopsin. In Molecular and Cellular Approaches for Diversifying and Extending Optogenetics, Gradinaru et al review current optogenetic methodology, and introduce eNpHR3.0-2A-ChR2, a genetic vector whose expression allows both action potential silencing and firing via illumination. This vector uses post-translational cleavage (via cis-acting hydrolase elements) [...]... Read more »

  • March 26, 2010
  • 03:35 PM

Self-destruction of the mirror neuron theory of action understanding

by Greg Hickok in Talking Brains

Rizzolatti & Sinigaglia's new Nature Reviews Neuroscience paper on the mirror system is effectively an admission that the mirror neuron theory of action understanding is wrong. The original is idea was interesting: we understand actions by mirroring those actions in our own motor system. But this is no longer the case according to R&S:By matching individual movements, mirror processing provides a representation of body part movement that might serve various functions (for example, imitation), b........ Read more »

  • March 26, 2010
  • 02:50 PM

On the Phenomena of Lightning

by Alexander in The Astronomist.

Thunderstorms are epic demonstrations of nature that can be quite fascinating when they aren't terrifying. The study of thunderstorms, in particular lightning, is of obvious practical interest, but also there is also a purely aesthetic and amusing aspect to them.... Read more »

Siingh, D., Singh, A., Patel, R., Singh, R., Singh, R., Veenadhari, B., & Mukherjee, M. (2009) Thunderstorms, Lightning, Sprites and Magnetospheric Whistler-Mode Radio Waves. Surveys in Geophysics, 29(6), 499-551. DOI: 10.1007/s10712-008-9053-z  

  • March 26, 2010
  • 01:55 PM

No free lunch in the Land of Cockaigne

by Lucas in thoughtomics

Life is hard for free-living microbes. Many of them undertake great efforts to obtain their energy, some get it directly from sunlight while others derive it from unusual compounds. To them, living inside an animal gut must be like living in some mythical land of plenty. Consider the luxuries! The lucky resident of a [...]... Read more »

Cleveland, L., & Grimstone, A. (1964) The Fine Structure of the Flagellate Mixotricha paradoxa and Its Associated Micro-Organisms. Proceedings of the Royal Society of London. Series B, Biological Sciences (1934-1990), 159(977), 668-686. DOI: 10.1098/rspb.1964.0025  

Tamas I, Wernegreen JJ, Nystedt B, Kauppinen SN, Darby AC, Gomez-Valero L, Lundin D, Poole AM, & Andersson SG. (2008) Endosymbiont gene functions impaired and rescued by polymerase infidelity at poly(A) tracts. Proceedings of the National Academy of Sciences of the United States of America, 105(39), 14934-9. PMID: 18815381  

  • March 26, 2010
  • 01:25 PM

Begging meerkat pups

by DeLene Beeland in Wild Muse

Learning about animal behavior never fails to fascinate me, and so it was with great interest that I read a recent paper on how meerkat pups alter their food-begging behavior depending upon the adult meerkat that they are nearest to. {1} Not all adults are created equal, it seems, in the world of a [...]... Read more »

  • March 26, 2010
  • 01:06 PM

An overview of Roche's oncology pipeline

by Sally Church in Pharma Strategy Blog

At last weeks investor meeting held by Roche in downtown Wall Street, the Board reviewed the pipeline opportunities in a number of areas. Earlier this week I wrote about the non-oncology pipeline and today will form an overview of the...... Read more »

  • March 26, 2010
  • 11:55 AM

Is Jesus Making You Overeat?

by Peter Janiszewski, PhD in Obesity Panacea

Well, in fairness, Jesus' twelve Apostles should also share in the blame.

An incredibly quirky and yet fascinating study was just published in the International Journal of Obesity which investigated the size of the food and plates that have been depicted in paintings of Jesus' Last Supper over the last 1000 years.
... Read more »

  • March 26, 2010
  • 11:09 AM

Does Contact Cure Mental Illness Stigma?

by Ultimo167 in Strong Silent Types

A brief overview by West et al. (2010) on mental illness stigma, in which the authors call for more focused research to improve understanding of this most unpalatable social problem.... Read more »

West, K., Hewstone, M., & Holmes, E. (2010) Rethinking 'Mental Health Stigma'. The European Journal of Public Health, 20(2), 131-132. DOI: 10.1093/eurpub/ckq015  

  • March 26, 2010
  • 09:12 AM

Gamers Take Heart: Cyberball game Helps Researchers Study Oxytocin Treatment for Autism Spectrum Disorders

by Kelly Grooms in Promega Connections

I confess I don’t play video games. My friends do, my husband does, but to me they always seemed a colossal waste of time. Time I could spend reading, or writing, or cornering the dust bunnies under the bed and tossing them out to fend for themselves. So when I started reading a paper about [...]... Read more »

Andari E, Duhamel JR, Zalla T, Herbrecht E, Leboyer M, & Sirigu A. (2010) Promoting social behavior with oxytocin in high-functioning autism spectrum disorders. Proceedings of the National Academy of Sciences of the United States of America, 107(9), 4389-94. PMID: 20160081  

  • March 26, 2010
  • 07:02 AM

The Mystery of the Siberian Pinkie: When Classification goes Wrong

by Malte Ebach in Systematics and Biogeography

Biological classification is often misunderstood and misused in the scientific literature and especially in the media:“... birds are dinosaurs” (New York Times, 2010).“Humans are apes” (Dawkins, 2010 in The Australian).“Scientists have identified a previously unknown type of ancient human through analysis of DNA from a finger bone unearthed in a Siberian cave” (BBC News Online).These slogans, popular with the public, are completely misinformed and provide inaccurate information about........ Read more »

He, Y., Wu, J., Dressman, D., Iacobuzio-Donahue, C., Markowitz, S., Velculescu, V., Diaz Jr, L., Kinzler, K., Vogelstein, B., & Papadopoulos, N. (2010) Heteroplasmic mitochondrial DNA mutations in normal and tumour cells. Nature, 464(7288), 610-614. DOI: 10.1038/nature08802  

  • March 26, 2010
  • 06:51 AM

Decision makers want information…or do they?

by David Winter in Careers - in Theory

A new research paper claims that decision makers value information more than advice. Is that really true?... Read more »

Dalal, R., & Bonaccio, S. (2010) What types of advice do decision-makers prefer?. Organizational Behavior and Human Decision Processes. DOI: 10.1016/j.obhdp.2009.11.007  

  • March 26, 2010
  • 06:13 AM

Wrapping up

by iayork in Mystery Rays from Outer Space

How does a viral genome get into a viral capsid?
There are several strategies, but often the viral capsid is built first, leaving a pore open at one corner; and then the viral genome is fed into that pore, getting neatly wrapped up around scaffolding proteins like a spool of thread.
Herpesviruses follow that strategy, and here’s [...]... Read more »

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