Based on two psychiatric assessment procedures, a computer program investigating the presence of a psychotic disorder and a personality questionnaire, Salvador Dali was found to have a personality disorder for DSM Cluster A and B. He was also found to meet the diagnostic criteria for psychotic illnesses.
You can’t diagnose psychiatric illness without doing a face [...]... Read more »
Murphy, C. (2009) The link between artistic creativity and psychopathology: Salvador Dalí. Personality and Individual Differences, 46(8), 765-774. DOI: 10.1016/j.paid.2009.01.020
Recently I tried to make this case that a mutation in my mitochondrial DNA
didn't make me so very different than the rest of you:
Our typical conception of mutation is drawn from the tragic effects of those
relatively rare mutations, induced in our bodies or passed on through germ
cells, that lead to diseases (or, in movies to super powers). In fact, we
are, each of us, mutants. DNA replication is not perfect, we are born with about
6 or 7 new mutations...
Well, a paper published last ........ Read more »
Xue, Y., Wang, Q., Long, Q., Ng, B., Swerdlow, H., Burton, J., Skuce, C., Taylor, R., Abdellah, Z., & Zhao, Y. (2009) Human Y Chromosome Base-Substitution Mutation Rate Measured by Direct Sequencing in a Deep-Rooting Pedigree. Current Biology. DOI: 10.1016/j.cub.2009.07.032
In their most recent article, Sommer, Dantas and Church have hit upon the craigslist for antibiotic resistance used by bacteria living in the human body. The basic genomic material needed for antibiotic resistance is readily available at your local bacterial community. Resistance genes are everywhere, and it is clear that, despite transmission barriers between species, they are transmitted. Bacteria have a large pool form which to draw new resistance genes. The arms race between drug developer........ Read more »
Sommer, M., Dantas, G., & Church, G. (2009) Functional Characterization of the Antibiotic Resistance Reservoir in the Human Microflora. Science, 325(5944), 1128-1131. DOI: 10.1126/science.1176950
The recent emergence of study into ‘pacing’ or activity regulation in pain management is a welcome addition to our knowledge of this coping strategy. Although pacing has been described and included in many self-help books as well as clinical texts as an effective strategy for people with chronic pain to use, the research base [...]... Read more »
Karsdorp, P., & Vlaeyen, J. (2009) Active avoidance but not activity pacing is associated with disability in fibromyalgia. Pain. DOI: 10.1016/j.pain.2009.07.019
As a medical association in Spain has recently communicated to the press, more than anything there seems to be an epidemic of fear going on. As I am currently living in Portugal, I do not know what the situation is in other countries, but I can tell you how the situation is here. Every news bulletin starts with more news about the flu, even though no one has died here yet. It then finishes with a previously recorded warning on how one should wash hands frequently and keep 1m away from other peop........ Read more »
Garten RJ, Davis CT, Russell CA, Shu B, Lindstrom S, Balish A, Sessions WM, Xu X, Skepner E, Deyde V.... (2009) Antigenic and genetic characteristics of swine-origin 2009 A(H1N1) influenza viruses circulating in humans. Science (New York, N.Y.), 325(5937), 197-201. PMID: 19465683
Garten, R., Davis, C., Russell, C., Shu, B., Lindstrom, S., Balish, A., Sessions, W., Xu, X., Skepner, E., Deyde, V.... (2009) Antigenic and Genetic Characteristics of Swine-Origin 2009 A(H1N1) Influenza Viruses Circulating in Humans. Science, 325(5937), 197-201. DOI: 10.1126/science.1176225
Maines TR, Jayaraman A, Belser JA, Wadford DA, Pappas C, Zeng H, Gustin KM, Pearce MB, Viswanathan K, Shriver ZH.... (2009) Transmission and pathogenesis of swine-origin 2009 A(H1N1) influenza viruses in ferrets and mice. Science (New York, N.Y.), 325(5939), 484-7. PMID: 19574347
Itoh, Y., Shinya, K., Kiso, M., Watanabe, T., Sakoda, Y., Hatta, M., Muramoto, Y., Tamura, D., Sakai-Tagawa, Y., Noda, T.... (2009) In vitro and in vivo characterization of new swine-origin H1N1 influenza viruses. Nature. DOI: 10.1038/nature08260
Nearly everyone seems to carry a mobile phone these days. What if social scientists could exploit this technology to spy on our social behaviour: who we speak to and who we spend time with? It turns out they already are. Nathan Eagle, named recently as a leading young innovator by Technology Review, and his colleagues, have published one of the first studies into social network analysis using spy software loaded onto Nokia smartphones.For nine months, Eagle's team recorded data from the phones ........ Read more »
Eagle, N., Pentland, A., & Lazer, D. (2009) Inferring friendship network structure by using mobile phone data. Proceedings of the National Academy of Sciences. DOI: 10.1073/pnas.0900282106
Here are two stories involving recent psychological/anthropological/biological research:In Future, Science Could Erase Traumatic Memories (NPR)The Culture of Being Rude (Smithsonian Magazine)As to the first, while describing an interesting study, the story itself is characteristically media. We can pinpoint the amygdala as being the "source" of the flight-or-fight (ie, fear) response, and we have now learned that as we (or, at least, as rats) grow, a "protective molecular sheath" coats the cells........ Read more »
Gogolla N, Caroni P, Lüthi A, & Herry C. (2009) Perineuronal nets protect fear memories from erasure. Science (New York, N.Y.), 325(5945), 1258-61. PMID: 19729657
Fincher CL, Thornhill R, Murray DR, & Schaller M. (2008) Pathogen prevalence predicts human cross-cultural variability in individualism/collectivism. Proceedings. Biological sciences / The Royal Society, 275(1640), 1279-85. PMID: 18302996
The model of fear extinction originated from the Pavlovian classical conditioning paradigm in the early 1900s. Defined as a reduction in a conditioned fear response following a non reinforced exposure to a feared conditioned stimulus, fear extinction is known to involve the amygdala and medial prefrontal cortex (mPFC). It's also a frequently striven-for goal in cognitive behavioral therapy during the treatment of various phobias including arachibutyrophobia; the fear of peanut butter sticking to........ Read more »
Kim JH, Hamlin AS, & Richardson R. (2009) Fear extinction across development: the involvement of the medial prefrontal cortex as assessed by temporary inactivation and immunohistochemistry. The Journal of neuroscience : the official journal of the Society for Neuroscience, 29(35), 10802-8. PMID: 19726637
Japan kills over a hundred minke whales each year under the guise of “scientific whaling”, and much of the meat ends up in the commercial markets destined for Japanese dinner plates. Now a study just published in Animal Conservation indicates that a similar number of whales are killed as “bycatch” in Japanese coastal waters, [...]... Read more »
Lukoschek, V., Funahashi, N., Lavery, S., Dalebout, M., Cipriano, F., & Baker, C. (2009) High proportion of protected minke whales sold on Japanese markets is due to illegal, unreported or unregulated exploitation. Animal Conservation. DOI: 10.1111/j.1469-1795.2009.00302.x
Does this look like a religious woman to you? According to a study by Prof Richard Wiseman in the New Scientist in February this year (hey, I've only just read it, OK?), this is a typical face of a religious person in the UK.What they did was to ask readers to send in photos of themselves, along with a rating of their personality. They digitised the key features, and produced an average of each personality type. When other people were asked to guess the personality based on face alone, they wer........ Read more »
Rees, TJ. (2009) Is Personal Insecurity a Cause of Cross-National Differences in the Intensity of Religious Belief?. Journal of Religion and Society. DOI: http://moses.creighton.edu/JRS/2009/2009-17.html
The authors report that in 2106 consecutive patients 65 years or older admitted for syncope, "Postural blood pressure (BP) recording, performed in only 38% of episodes, had the highest yield with respect to affecting diagnosis (18%-26%) or management (25%-30%) and determining etiology of the syncopal episode (15%-21%)...... Read more »
Mendu ML, McAvay G, Lampert R, Stoehr J, & Tinetti ME. (2009) Yield of diagnostic tests in evaluating syncopal episodes in older patients. Archives of internal medicine, 169(14), 1299-305. PMID: 19636031
Lasers which can control the movement of particles are still confined to the microscopic world, but if you have an over-reactive imagination, you might wonder just what the limits are on the size of bodies which these devices can control and whether science fiction's tractor beams are becoming a reality. Today's technology may not be capable of producing force fields that lock on to starships and guide them in to land, but the size of particles which can be manipulated by light are getting large........ Read more »
Applegate Jr., R., Marr, D., Squier, J., & Graves, S. (2009) Particle size limits when using optical trapping and deflection of particles for sorting using diode laser bars. Optics Express, 17(19), 16731. DOI: 10.1364/OE.17.016731
Google-like algorithm pinpoints key species in food web
... Read more »
Allesina, S., & Pascual, M. (2009) Googling Food Webs: Can an Eigenvector Measure Species' Importance for Coextinctions?. PLoS Computational Biology, 5(9). DOI: 10.1371/journal.pcbi.1000494
Can biologists and mathematicians accomplish more together than working separately? My answer to that question has always been a resounding yes but today I am backing up that statement with a piece of research: the result of a collaboration involving mathematicians and biologists (and a pathologist) in Tampa, Nashville and Houston.
Basanta, D., Strand, D., Lukner, R., Franco, O., Cliffel, D., Ayala, G., Hayward, S., & Anderson, A. (2009). The Role of Transforming Growth Factor- -M........ Read more »
Basanta, D., Strand, D., Lukner, R., Franco, O., Cliffel, D., Ayala, G., Hayward, S., & Anderson, A. (2009) The Role of Transforming Growth Factor- -Mediated Tumor-Stroma Interactions in Prostate Cancer Progression: An Integrative Approach. Cancer Research, 69(17), 7111-7120. DOI: 10.1158/0008-5472.CAN-08-3957
I admit it, I”m a sucker for any argument that turns an established paradigm on its head. It’s hard to beat that little thrill you get when you realize everything we thought we knew may be wrong!
My favorite iconoclast in the advertising research world is Robert Heath, a former ad man turned academic whose home [...]... Read more »
Heath, R. (2001) Low involvement processing - a new model of brand communication. Journal of Marketing Communications, 7(1), 27-33. DOI: 10.1080/13527260123019
Du Plessis, E., & Hollis, N. (2002) Low involvement processing - is it HIP enough?. Admap, July 2002(Issue 430), 36-38. info:/
Heath, R., Brandt, D., & Nairn, A. (2006) Brand Relationships: Strengthened by Emotion, Weakened by Attention. Journal of Advertising Research, 46(4), 410. DOI: 10.2501/S002184990606048X
My first post to this blog will begin with a thought provoking paper on how the olfactory system fits in to the longevity promoting effects of calorie restriction.
Calorie restriction is the most studied and reliable way to extend secondary and maximal lifespan, tested in many species since the 1930’s up to recently in rhesus monkeys and preliminary human data.
Why the mechanisms of calorie restriction have been so well conserved throughout species is still an enigma; species in natu........ Read more »
The XML Summer School returns this year at St. Edmund Hall, Oxford from 20th-25th September 2009. As always, it’s packed with high quality technical XML training for every level of expertise, from the Hands-on Introduction through to special classes devoted to XQuery and XSLT, Semantic Technologies, Open Source Applications, Web 2.0, Web Services and Identity. [...]... Read more »
Mike Hucka. (2003) The systems biology markup language (SBML): a medium for representation and exchange of biochemical network models. Bioinformatics, 19(4), 524-531. DOI: 10.1093/bioinformatics/btg015
Bunduchi R, Williams R, Graham I, & Smart A. (2006) XML-based clinical data standardisation in the National Health Service Scotland. Informatics in primary care, 14(4), 227. PMID: 17504574
Sayers, E., Barrett, T., Benson, D., Bryant, S., Canese, K., Chetvernin, V., Church, D., DiCuccio, M., Edgar, R., Federhen, S.... (2009) Database resources of the National Center for Biotechnology Information. Nucleic Acids Research, 37(Database). DOI: 10.1093/nar/gkn741
pDomestic dogs are very different from their wolf ancestors in their bodies and their behaviour. They're more docile for a start. But man's best friend has also evolved a curious sensitivity to our communication signals - a mental ability that sets them apart from wolves and that parallels the behaviour of human infants. Dogs and infants are even prone to making the same mistakes of perception.
Like infants less than a year old, dogs fail at a seemingly easy exercise called the "object permane........ Read more »
Topal, J., Gergely, G., Erdohegyi, A., Csibra, G., & Miklosi, A. (2009) Differential Sensitivity to Human Communication in Dogs, Wolves, and Human Infants. Science, 325(5945), 1269-1272. DOI: 10.1126/science.1176960
What do teachers think is the primary purpose of homework? How much do they think parents should be involved? How do those attitudes effect student effort and achievement?
A group of researchers studying teachers in Switzerland (hey! a non-US study!) conducted a survey of 93 teachers of French as a second language. Their survey included scales [...]... Read more »
Trautwein, U., Niggli, A., Schnyder, I., & Lüdtke, O. (2009) Between-teacher differences in homework assignments and the development of students' homework effort, homework emotions, and achievement. Journal of Educational Psychology, 101(1), 176-189. DOI: 10.1037/0022-06188.8.131.52
One of the limitations of antidepressants is that they don't always work. Worse, they don't work in an unpredictable way. Some people benefit from some drugs, and others don't, but there's no way of knowing in advance what will happen in any particular case - or of telling which pill is right for which person.As a result, drug treatment for depression generally involves starting with a cheap medication with relatively mild side-effects, and if that fails, moving onto a series of other drugs unti........ Read more »
Leuchter AF, Cook IA, Gilmer WS, Marangell LB, Burgoyne KS, Howland RH, Trivedi MH, Zisook S, Jain R, Fava M.... (2009) Effectiveness of a quantitative electroencephalographic biomarker for predicting differential response or remission with escitalopram and bupropion in major depressive disorder. Psychiatry research. PMID: 19709754
Leuchter AF, Cook IA, Marangell LB, Gilmer WS, Burgoyne KS, Howland RH, Trivedi MH, Zisook S, Jain R, McCracken JT.... (2009) Comparative effectiveness of biomarkers and clinical indicators for predicting outcomes of SSRI treatment in Major Depressive Disorder: Results of the BRITE-MD study. Psychiatry research. PMID: 19712979
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