Post List

  • December 21, 2010
  • 02:49 PM

Fetal Testosterone and Autistic Traits - Part IV: Verbal Abilities

by Lindsay in Autist's Corner

Part of an ongoing series examining the evidence for Simon Baron-Cohen's "extreme male brain" theory of autism... Read more »

Lutchmaya, S., Baron-Cohen, S., & Raggatt, P. (2001) Foetal testosterone and vocabulary size in 18- and 24-month-old infants. Infant Behavior and Development, 24(4), 418-424. DOI: 10.1016/S0163-6383(02)00087-5  

  • December 21, 2010
  • 02:38 PM

DNMT3A Mutations in Acute Myeloid Leukemia – an update

by Sally Church in Pharma Strategy Blog

The current New England Journal of Medicine has an in-depth article on DNMT3A Mutations in Acute Myeloid Leukemia (AML).   Many of you will remember the discussion on this topic last month based on the two case studies that the … Continue reading →... Read more »

Ley, T., Ding, L., Walter, M., McLellan, M., Lamprecht, T., Larson, D., Kandoth, C., Payton, J., Baty, J., Welch, J.... (2010) Mutations in Acute Myeloid Leukemia . New England Journal of Medicine, 363(25), 2424-2433. DOI: 10.1056/NEJMoa1005143  

  • December 21, 2010
  • 02:07 PM

Neuroradiology as Art

by The Neurocritic in The Neurocritic

Crucifixion, by Francis Bacon (1933).Crucifixion (1933) (oil on canvas) was subsequently purchased by Sir Michael Sadler (who, other than friends or relations, was the first to buy a painting), and who also commissioned a second version, Crucifixion (1933) (chalk, gouache and pencil), and sent Bacon an x-ray photograph of his own skull, with a request that he paint a portrait from it. Bacon duly incorporated the x-ray directly into The Crucifixion (1933).A paper by an interdisciplinary team of S........ Read more »

Marinkovic, S., Stošic-Opincal, T., Štrbac, M., Tomic, I., Tomic, O., & Djordjevic, D. (2010) Neuroradiology and Art: A Review and Personal Contribution. The Tohoku Journal of Experimental Medicine, 222(4), 297-302. DOI: 10.1620/tjem.222.297  

  • December 21, 2010
  • 01:39 PM

What Mirror Images and Foreign Scripts Tell Us About the Reading Brain

by Livia Blackburne in A Brain Scientist's Take on Writing

Here’s a simple exercise. Count the number of times the letter ‘A’ appears in the sentences below. Easy enough, but, there's a catch. You have to do it without reading the words.


One day, after Little Red Riding hood woke up, mother called her into the kitchen and handed her a basket of cakes and pastries. “Take these to grandmother. She's sick, and perhaps these cakes will make her feel better.”

If you have been reading for years, you probably found it difficult, if not imp........ Read more »

Baker CI, Liu J, Wald LL, Kwong KK, Benner T, & Kanwisher N. (2007) Visual word processing and experiential origins of functional selectivity in human extrastriate cortex. Proceedings of the National Academy of Sciences of the United States of America, 104(21), 9087-92. PMID: 17502592  

  • December 21, 2010
  • 11:17 AM

Is XMRV a laboratory contaminant?

by Vincent Racaniello in virology blog

Since the first observations that the human retrovirus XMRV is associated with prostate cancer and chronic fatigue syndrome (CFS), new studies have been carried out to determine the role of the virus in these diseases. The results have been conflicting: XMRV (and related retroviruses) have been found in some patients, but not in others. Whether laboratory contamination [...]... Read more »

Stephane Hue, Eleanor R Gray, Astrid Gall, Aris Katzourakis, Choon Ping Tan, Charlotte J Houldcroft, Stuart McLaren, Deenan Pillay, Andrew Futreal, Jeremy A Garson.... (2010) Disease-associated XMRV sequences are consistent with laboratory contamination. Retrovirology. info:/

  • December 21, 2010
  • 10:09 AM

Pass the Salad, Please: Many Theropods Ate Plants

by Brian Switek in Dinosaur Tracking

Coelurosaurs were one of the strangest groups of dinosaurs. In addition to the famous predators Tyrannosaurus and Velociraptor, the coelurosaurs included the small, fuzzy Sinosauropteryx; “ostrich-mimics” such as Struthiomimus; the long-necked, sickle-clawed giant Therizinosaurus; the tiny, ant-eating Albertonykus; the bird-beaked oviraptorosaurs like Citipati; and birds. Within the past decade, especially, new discoveries have radically changed [...]... Read more »

Yoshitsugu Kobayashi and Jun-Chang Lü. (2003) A new ornithomimid dinosaur with gregarious habits from the Late Cretaceous of China. Acta Palaeontologica Polonica, 48(2), 235-259. info:/

  • December 21, 2010
  • 09:05 AM

Under the mistletoe, coevolution is about s and m

by Jeremy Yoder in Denim and Tweed

Plants and plant products, from sprigs of holly to pine boughs, have been traditional winter holiday decorations since before Christmas became Christmas. Nowadays, if we don't resort to plastic imitations, we deck our halls with garlands from a nursery and a tree from a farm. But seasonal decorations have natural histories apart from mantelpieces and door frames—ecological roles and, yes, coevolutionary interactions with other species.

.flickr-photo { }.flickr-frameright { float: right; text........ Read more »

  • December 21, 2010
  • 08:17 AM

A Christmas tree in the eye

by Debajyoti Datta in Medicine...Life

Medicine never ceases to amaze.  I just read a case report published in the BMJ by Ebube E Obi and C Weir about a Christmas tree cataract. I have seen some cases of cataract but I have not seen a Christmas tree cataract. May be sometime in future I will.They report a case of a 73 year old woman who presented with a Christmas tree cataract of the left eye.... Read more »

Obi, E., & Weir, C. (2010) A Christmas tree cataract. BMJ, 341(dec08 3). DOI: 10.1136/bmj.c6644  

Shun-Shin GA, Vrensen GF, Brown NP, Willekens B, Smeets MH, & Bron AJ. (1993) Morphologic characteristics and chemical composition of Christmas tree cataract. Investigative ophthalmology , 34(13), 3489-96. PMID: 8258504  

  • December 21, 2010
  • 07:06 AM

Paralysis deniers have subconscious insight into their disability

by BPS Research Digest in BPS Research Digest

Anosognosia is an intriguing neuropsychological syndrome in which a patient with one or more paralysed limbs denies they have anything wrong with them. In a new investigation, Aikaterini Fotopoulou and her colleagues have shown that some patients fitting this description have a residual, sub-conscious awareness of their disability.

The researchers recruited 14 brain-damaged patients with a completely paralysed left arm, half of whom denied their paralysis (ie they had anosognosia). Next, a........ Read more »

  • December 21, 2010
  • 07:00 AM

Defining UX – and a Merry Christmas 2010!

by Simon Harper in Thinking Out Loud

As a positivist research scientist I've been struggling with the whole User Experience (UX) space for a long time, because to me it just seems a bit - well - 'fluffy'.... Read more »

Law, Effie Lai-Chong and Roto, Virpi and Hassenzahl, Marc and Vermeeren, Arnold P.O.S. and Kort, Joke. (2009) Understanding, scoping and defining user experience: a survey approach. Proceedings of the 27th international conference on Human factors in computing systems, 1(1), 719-728. info:/10.1145/1518701.1518813

  • December 21, 2010
  • 07:00 AM

Low-Carbohydrate Diets are Not Created Equal

by Shaheen Lakhan in Brain Blogger

Low-carbohydrate diets have been among the most popular weight-loss strategies of the last several decades. But, new research published in the Annals of Internal Medicine indicates that the type of low-carbohydrate plan one chooses affects not only the waistline, but the risk of mortality. In a large, prospective, observational study, researchers evaluated whether the type [...]... Read more »

Fung TT, van Dam RM, Hankinson SE, Stampfer M, Willett WC, & Hu FB. (2010) Low-carbohydrate diets and all-cause and cause-specific mortality: two cohort studies. Annals of internal medicine, 153(5), 289-98. PMID: 20820038  

Halton TL, Willett WC, Liu S, Manson JE, Albert CM, Rexrode K, & Hu FB. (2006) Low-carbohydrate-diet score and the risk of coronary heart disease in women. The New England journal of medicine, 355(19), 1991-2002. PMID: 17093250  

Kennedy ET, Bowman SA, Spence JT, Freedman M, & King J. (2001) Popular diets: correlation to health, nutrition, and obesity. Journal of the American Dietetic Association, 101(4), 411-20. PMID: 11320946  

Sjögren P, Becker W, Warensjö E, Olsson E, Byberg L, Gustafsson IB, Karlström B, & Cederholm T. (2010) Mediterranean and carbohydrate-restricted diets and mortality among elderly men: a cohort study in Sweden. The American journal of clinical nutrition, 92(4), 967-74. PMID: 20826627  

Trichopoulou A, Psaltopoulou T, Orfanos P, Hsieh CC, & Trichopoulos D. (2007) Low-carbohydrate-high-protein diet and long-term survival in a general population cohort. European journal of clinical nutrition, 61(5), 575-81. PMID: 17136037  

  • December 21, 2010
  • 06:19 AM

Today on arxiv

by Marco Frasca in The Gauge Connection

I would like to write down a few lines on a paper published today on arxiv by Axel Maas (see here). This author draws an important conclusion about the propagators in Yang-Mills theories: These functions depend very few on the gauge group, keeping  fixed the coupling a la ‘t Hooft as being  a Casimir parameter of [...]... Read more »

  • December 21, 2010
  • 05:30 AM

Excitable motility

by Becky in It Takes 30

We’ve talked before about the puzzle of how cells like neutrophils figure out how to follow a shallow gradient of attractive chemicals.  In a recent paper (Xiong et al, 2010.  Cells navigate with a local-excitation, global-inhibition excitable network.  PNAS, PMID 20864631) the Devreotes and Iglesias labs describe a new model of how chemotaxis might work.  [...]... Read more »

Xiong Y, Huang CH, Iglesias PA, & Devreotes PN. (2010) Cells navigate with a local-excitation, global-inhibition-biased excitable network. Proceedings of the National Academy of Sciences of the United States of America, 107(40), 17079-86. PMID: 20864631  

  • December 21, 2010
  • 04:22 AM

re: Commercial or Proprietary?

by egonw in Chem-bla-ics

OK, the second paper I ran into today is a perfect match for the paper by Khanna and Ranganathan I just dicussed in the Commercial or Proprietary? post. So perfect, in fact, that it I should have really combined them. But since the other post is already infecting the WWW, I'll have to post this update.

Yap wrote up a paper on PaDEL-descriptor: An open source software to calculate molecular descriptors and fingerprints (doi:10.1002/jcc.21707), and Table 2 is quite like Table 1 in the paper by Kh........ Read more »

  • December 21, 2010
  • 04:13 AM

Self-organising principles in the nervous system

by Kevin Mitchell in Wiring the Brain

The circuitry of the brain is too complex to be completely specified by genetic information – at least not down to the level of each connection. There are hundreds of billions of neurons in your brain, each making an average of 1,000 connections to other cells. There are simply not enough genes in the genome to specify all of these connections. What the genetic program can achieve is a very good wiring diagram of initial projections between neurons in different brain areas (or layers or bet........ Read more »

Kaschube M, Schnabel M, Löwel S, Coppola DM, White LE, & Wolf F. (2010) Universality in the evolution of orientation columns in the visual cortex. Science (New York, N.Y.), 330(6007), 1113-6. PMID: 21051599  

  • December 21, 2010
  • 03:29 AM

My article « A History of Virulence » finally published in Body and Society

by ---a in

Sage journal Body and Society vol 16, n. 4 is finally out! Pardon my enthusiasm, but this issue features my 30-page essay A History of Virulence: The Body and Computer Culture in the 1980s: a killer mix of hackerdom, virality and computer nostalgia that also happens to be IMHO one hell of a contribution to [...]... Read more »

  • December 21, 2010
  • 02:00 AM

Love ballads leave women more open to romance

by SAGE Insight in SAGE Insight

‘Love is in the air’: Effects of songs with romantic lyrics on compliance with a courtship request From Psychology of Music If you’re having trouble getting a date, French researchers suggest that picking the right soundtrack could improve the odds. There’s plenty of research indicating that the media affects our behavior but this study specifically [...]... Read more »

  • December 21, 2010
  • 01:22 AM

Dark Chocolate Receptor

by Dr Shock in Dr Shock MD PhD

They tested the protection of epicatechin on heart infarct size in mice. Epicatechin is a flavinoid and a major component of dark chocolate. It has antioxydant effects associated with a lower risk of stroke and heart failure. Epicatechin can bind to opiod receptors that can induce heart protection, moreover it can induce cardiac protection from [...]

Related posts:Dark Chocolate to prevent Hypertension?
Dark Chocolate More Flavonoids
Dark Chocolate Improves Coronary Blood Flow
... Read more »

Panneerselvam, M., Tsutsumi, Y., Bonds, J., Horikawa, Y., Saldana, M., Dalton, N., Head, B., Patel, P., Roth, D., & Patel, H. (2010) Dark chocolate receptors: epicatechin-induced cardiac protection is dependent on  -opioid receptor stimulation. AJP: Heart and Circulatory Physiology, 299(5). DOI: 10.1152/ajpheart.00073.2010  

  • December 20, 2010
  • 05:47 PM

Has the online search displaced the friend as the preferred first information source?

by Christina Pikas in Christina's LIS Rant

Review of a JASIST article looking at selection of information sources: co-workers or electronic resources.... Read more »

  • December 20, 2010
  • 04:15 PM

Is Beauty More Rewarding for Men II?

by whooke in The Psychology of Beauty

It’s been too long since I have made regular postings to the Beauty Blog.  I am happy to report that I am back and ready to go!  Just to get started, I have decided that every so often I will be revisiting the topics of earlier postings, emphasizing how subsequent research supports – and does [...]... Read more »

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