Post List

  • May 10, 2010
  • 12:22 PM
  • 825 views

Understanding triple negative breast cancer – 53BP1 and the BRCA1 connection

by Cancer Research UK in Cancer Research UK - Science Update

Over the years, Cancer Research UK has helped transform breast cancer treatment – now 8 out of 10 women survive their disease for more than 5 years, compared with 5 out of 10 women in the 1970s. Most of this progress has been made in so-called hormone-sensitive cancers – those that are fuelled by the [...]... Read more »

Bouwman, P., Aly, A., Escandell, J., Pieterse, M., Bartkova, J., van der Gulden, H., Hiddingh, S., Thanasoula, M., Kulkarni, A., Yang, Q.... (2010) 53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers. Nature Structural . DOI: 10.1038/nsmb.1831  

  • May 10, 2010
  • 12:15 PM
  • 1,200 views

Affordances, Part 1: Affordances are real dispositions of the environment

by Andrew Wilson in Notes from Two Scientific Psychologists

A key concept in ecological psychology is that of affordances. There is still uncertainty how to characterise these (slightly odd) properties, and the first formal attempt was by Turvey (1992).... Read more »

  • May 10, 2010
  • 12:00 PM
  • 814 views

Why it's time for the media to help our politicians believe they can succeed

by BPS Research Digest in BPS Research Digest

A psychology study fresh off the presses shows the importance of positive expectations for the successful resolution of awkward negotiations. The results couldn't be more timely as our senior politicians negotiate over terms for a new coalition British government - the first since the 1970s. The finding suggests that the media has a vital role to play. By fostering optimism in the likely success of the negotiations, the media could help increase the likelihood of a successful resolution.In an in........ Read more »

  • May 10, 2010
  • 11:13 AM
  • 14,926 views

For the Love of the Game: A Look at Fans and Disappointment

by Krystal D'Costa in Anthropology in Practice

What does it mean to be a baseball fan? To exchange high fives with complete strangers utterly swept away with the exhilaration of a win? To sit in your car, despondent, after a devastating loss? What is the fan’s connection to this game—billed as America’s pastime?

Before delving into this post, it’s only fair to report that I myself am a fan. So this is in part a self-reflexive exercise to... Read more »

Karl J. Franklin. (1985) Componential Analysis and the Game of Baseball. Anthropological Linguistics, 27(3), 281-301. info:/

  • May 10, 2010
  • 11:06 AM
  • 1,084 views

When manatees crossed the Atlantic

by Darren Naish in Tetrapod Zoology

No time for anything new (working on a book chapter and putting the finishing touches to the Tet Zoo book), so here's this, from the archives. NOT properly updated, so please be aware that it's more than four years old...

Read the rest of this post... | Read the comments on this post...... Read more »

  • May 10, 2010
  • 09:53 AM
  • 701 views

Tracking the Origin of Dinosaurs

by Brian Switek in Dinosaur Tracking

Almost everyone is familiar with the ongoing debate surrounding the extinction of the non-avian dinosaurs 65 million years ago, but the discussion over where dinosaurs came from in the first place is often overlooked. Hypotheses of dinosaur origins have been just as controversial as those of triggers for the end-Cretaceous mass extinction, but during the [...]... Read more »

Brusatte, S., Nesbitt, S., Irmis, R., Butler, R., Benton, M., & Norell, M. (2010) The origin and early radiation of dinosaurs. Earth-Science Reviews. DOI: 10.1016/j.earscirev.2010.04.001  

  • May 10, 2010
  • 09:39 AM
  • 588 views

Fast Food Logos Make People Hasty

by Daniel Hawes in Ingenious Monkey | 20-two-5

Fast food may make you fat, but mere thoughts of fast food can have wider reaching effects: Haste and impatience... Read more »

Chen-Bo Zhong, & Sanford E. DeVoe. (2010) You Are How You Eat: Fast Food and Impatience. Psycholgoical Science. info:/10.1177/0956797610366090

  • May 10, 2010
  • 09:12 AM
  • 2,054 views

rethinking petroleum a little too hard…

by Greg Fish in weird things

When you run a blog which focuses on skepticism and fact checking, you can occasionally discover that even a seemingly common, everyday, undisputed bit of science can have its detractors. About two months ago, two people who commented on my review of NatGeo’s dramatic what-if scenario about our future if all the oil in the [...]... Read more »

  • May 10, 2010
  • 09:00 AM
  • 700 views

Mountains of Pelagic Diversity

by Alistair Dove in Deep Type Flow


If you ever saw the dramatic seamount scene in Blue Planet (and if you haven’t, where ya been??), then you are probably familiar with the idea that submarine mountains can attract lots of animals; as Attenborough puts it, they “create oases where life can flourish in the comparatively empty expanses of the open ocean”.  In that spectacular BBC sequence, jacks and tuna swarm an Eastern Pacific ... Read more »

Morato, T., Hoyle, S., Allain, V., & Nicol, S. (2010) Seamounts are hotspots of pelagic biodiversity in the open ocean. Proceedings of the National Academy of Sciences. DOI: 10.1073/pnas.0910290107  

  • May 10, 2010
  • 08:30 AM
  • 1,173 views

Monday Pets: How Do Dogs Learn New Words?

by Jason Goldman in The Thoughtful Animal

...and what can word-learning in dogs teach us about the evolution of language in humans?

What is involved in the learning of a single new word? Consider the word "tiger", being learned by a child with already a modest vocabulary, at least for animal words. First the child must make a new entry in the mental lexicon - that "tiger" is a word in the first place. He has to categorize it as a noun. It has to be categorized under "animal" (a supernym) and related to its hyponyms, like "Sumatran tige........ Read more »

  • May 10, 2010
  • 08:12 AM
  • 989 views

WE CARE: Providing Portable Power Through Solar Suitcases

by agoldstein in WiSci

After witnessing a C-section performed by flashlight in Nigeria, Laura Stachel, an OB-GYN doctor at UC Berkley founded WE CARE (Women’s Emergency Communication and Reliable Electricity) Solar. To bring power to needy hospitals around the globe, she developed the solar suitcase: a portable solar electric system, used to power overhead LED lights and charge walkie-talkies, cell phones, and LED headlamp batteries.... Read more »

  • May 10, 2010
  • 08:00 AM
  • 601 views

Antidepressants Not Effective for Some Types of Depression

by Shaheen Lakhan in Brain Blogger

Antidepressant medications have been the mainstay of treatment for depressive disorders for decades. But these drugs may not be as effective as once believed, according to a new analysis published in the Journal of the American Medical Association (JAMA). Researchers at the University of Pennsylvania conducted a meta-analysis of data from trials of antidepressants and [...]... Read more »

Fournier, J., DeRubeis, R., Hollon, S., Dimidjian, S., Amsterdam, J., Shelton, R., & Fawcett, J. (2010) Antidepressant Drug Effects and Depression Severity: A Patient-Level Meta-analysis. JAMA: The Journal of the American Medical Association, 303(1), 47-53. DOI: 10.1001/jama.2009.1943  

  • May 10, 2010
  • 08:00 AM
  • 1,801 views

CO(a)Xing the Formation of Brown Fat

by Arya M. Sharma in Dr. Sharma's Obesity Notes


Regular readers of these pages will recall previous posts on the role of brown fat tissue and its potential role in the prevention of weight gain. This tissue, helps burn excess calories by directly converting them into heat - people with more brown fat may be less likely to become obese (click here for TV [...]... Read more »

Vegiopoulos A, Müller-Decker K, Strzoda D, Schmitt I, Chichelnitskiy E, Ostertag A, Diaz MB, Rozman J, Hrabe de Angelis M, Nüsing RM.... (2010) Cyclooxygenase-2 Controls Energy Homeostasis in Mice by de Novo Recruitment of Brown Adipocytes. Science (New York, N.Y.). PMID: 20448152  

  • May 10, 2010
  • 08:00 AM
  • 1,417 views

PubMed vs. Google Scholar

by Zen Faulkes in NeuroDojo

A comment on Twitter about PubMed left me wondering aloud why people use the thing instead of Google Scholar. This idle comment brought a surprising amount of comments.

Before I get to the comments, let me explain my point of view. I’ve never warmed to PubMed, although I know many of my peers use it multiple times daily. I suppose part of it is the “med” moniker. While PubMed does include a lot of the basic biological literature, it’s still fundamentally a medical resource. And I am not........ Read more »

  • May 10, 2010
  • 07:01 AM
  • 567 views

Food addiction, not obesity

by NeuroKüz in NeuroKüz

A look at a commentary that criticizes the concept of "food addiction"... Read more »

  • May 10, 2010
  • 06:00 AM
  • 907 views

Assessing the vulnerability of coasts to sea-level rise

by Rob Goldstein in Conservation Maven

Coastlines around the world will be affected by rising sea level over the next several decades. In some places, the impacts will be severe as flooding, erosion, and storm surge cause damage to coastal towns and transform habitats for coastal species. The big question for resource managers and planners: Where are the most vulnerable places?... Read more »

  • May 10, 2010
  • 05:00 AM
  • 794 views

Viagra could help women too, but not how you think…

by Helen Jaques in In Sickness and In Health

Since first coming on the market in 1998, erectile dysfunction drug Viagra has improved the lives of countless men. Now new research has suggested that phosphodiesterase 5 (PDE5) inhibitors like Viagra could also help women – but not how you think.
Researchers in California have shown that sildenafil (Viagra) and a similar drug called vardenafil [...]... Read more »

  • May 10, 2010
  • 03:40 AM
  • 833 views

Freud and Penfield were wrong about memory and it leads to woo

by Barbara Drescher in ICBS Everywhere

          
Don’t get me wrong, Sigmund Freud and Wilder Penfield were far more intelligent and successful than I, but in hindsight we now have evidence that disconfirms their models of memory. The costs of having an inaccurate model of how memory works are immense.  There are financial and opportunity costs to psychotherapy participants and on occasion [...]... Read more »

Loftus EF, & Loftus GR. (1980) On the permanence of stored information in the human brain. The American psychologist, 35(5), 409-20. PMID: 7386971  

McNally, N. (2003) Remembering Trauma. Cambridge: The Belknap Press of Harvard University. info:/

Quas JA, Goodman GS, Bidrose S, Pipe ME, Craw S, & Ablin DS. (1999) Emotion and memory: Children's long-term remembering, forgetting, and suggestibility. Journal of experimental child psychology, 72(4), 235-70. PMID: 10074380  

  • May 10, 2010
  • 03:04 AM
  • 1,470 views

Doctors are desensitised to other people's pain

by BPS Research Digest in BPS Research Digest

When you see someone else in pain, the pain network in your own brain winces as if you were experiencing their pain yourself. This is great for everyday empathy, but not necessarily so useful if you're a doctor. When you're the one wielding the needle or planning a treatment regimen, you need to make sure your concern for your patient's pain doesn't distract you from the task at hand. According to Jean Decety, doctors get around this conflict by reducing their sensitivity to other people's pain......... Read more »

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