I thought it would be fun to do a series on hot new trends in science and medicine based on different mechanisms of action, partly because this is what science is all about and partly because hearing about creative new...... Read more »
Di Fede, G., Catania, M., Morbin, M., Rossi, G., Suardi, S., Mazzoleni, G., Merlin, M., Giovagnoli, A., Prioni, S., Erbetta, A.... (2009) A Recessive Mutation in the APP Gene with Dominant-Negative Effect on Amyloidogenesis. Science, 323(5920), 1473-1477. DOI: 10.1126/science.1168979
A quite bizarre research paper appears in the inaugural issue of the International Journal of Critical Accounting, coincidentally the month the Metallica Guitar Hero pack is released. The paper is entitled: “Structural change in the music industry: a Marxist critique of public statements made by members of Metallica during the lawsuit against Napster”
The research paper [...]Post from: David Bradley's Sciencetext Tips and Tricks
Metallica, Napster, and Marx... Read more »
Kieran James, & Christopher Tolliday. (2009) Structural change in the music industry: a Marxist critique of public statements made by members of Metallica during the lawsuit against Napster. International Journal of Critical Accounting, 1(1), 144-176.
The use of ultrafast (femtosecond) lasers as a tool to see (image) the eye structures is reviewed. In particular, how multiphoton microscopes can be improved by aberration correction and how impressive images from ocular tissues could help diagnosis and treatment of eye's diseases... ... Read more »
Bueno, J., Vohnsen, B., Roso, L., & Artal, P. (2009) Temporal wavefront stability of an ultrafast high-power laser beam. Applied Optics, 48(4), 770. DOI: 10.1364/AO.48.000770
Four major US national laboratories have worked together to develop a computer model to help airport authorities screen passengers for pandemic influenza. The tool can detect false negatives, people with influenza who slip through the screening process, and so cut the risk of infected passengers unknowingly spreading disease across the nation.
During a confirmed outbreak of [...]... Read more »
Robert T. Brigantic, John D. Malone, George A. Muller, Russell Lee, & Jim Kulesz. (2009) Simulation to assess the efficacy of US airport entry screening of passengers for pandemic influenza. Int. J. Risk Assessment and Management, 12(2/3/4), 290-310.
Recently, some human survival data – together with matching gene expression data from lymphoblastoid cell lines – have become available from a long-range study that began in the early 1980s. In the first aging study to take advantage of this resource, Kerber et al. mine the data to identify gene changes associated with longevity:... Read more »
Kerber, R., O’Brien, E., & Cawthon, R. (2009) Gene expression profiles associated with aging and mortality in humans. Aging Cell, 8(3), 239-250. DOI: 10.1111/j.1474-9726.2009.00467.x
I certainly hope not because if a recent study holds true, if thinking about exercise causes your heart to race you're twice as likely to die of a sudden heart attack.Of course it occurs to me that the folks whose hearts are likeliest to race at the thought of exercise would be those who are the least fit as they'll be worried about the prospect of exercising which in turn might cause their adrenalin to flow and their hearts to race.So perhaps the results aren't so surprising - those who are the........ Read more »
Jouven, X., Schwartz, P., Escolano, S., Straczek, C., Tafflet, M., Desnos, M., Empana, J., & Ducimetiere, P. (2009) Excessive heart rate increase during mild mental stress in preparation for exercise predicts sudden death in the general population. European Heart Journal. DOI: 10.1093/eurheartj/ehp160
Is it possible to reconcile supply chain vulnerability, risk and supply chain management with corporate governance, business continuity, national security and emergency planning? In her 2006 article, Helen Peck attempts to do just that, hence my analogy of looking down at supply chains from Space – in order to really see the big picture. Because, in supply chains, most stakeholders are found far beyond the individual supply chain and Helen Peck explains why.... Read more »
Peck, H. (2006) Reconciling supply chain vulnerability, risk and supply chain management. International Journal of Logistics, 9(2), 127-142. DOI: 10.1080/13675560600673578
Recent gadgets such as the handheld portable Nintendo DS video game console, portable Sony Playstation Portable (PSP), iPhone and iPod touch go with video games. The advantage being obvious that any moment waiting can be used to play a video game.
Screens of these portable media consoles are comparable with television and video monitors in terms [...]... Read more »
Ivory, J., & Magee, R. (2009) You Can't Take It with You? Effects of Handheld Portable Media Consoles on Physiological and Psychological Responses to Video Game and Movie Content. CyberPsychology , 2147483647. DOI: 10.1089/cpb.2008.0279
This is the age of biotechnology, and many believe that one of the crowning triumphs of the age will be the defeat of cancer. If we're going to greatly extend healthy human longevity, then the defeat of cancer certainly has to be achieved one way or another. I think that the one of the most exciting possibilities in modern cancer research is that a cure for cancer is in fact easy, but we don't yet know how to do it. Let me explain what I mean by "easy." This is an era in which we can order cells........ Read more »
Rebecca J. Critchley-Thorne, Diana L. Simons, Ning Yana, Andrea K. Miyahira, Frederick M. Dirbas, Denise L. Johnson, Susan M. Swetter, Robert W. Carlson, George A. Fisher, Albert Koong.... (2009) Impaired interferon signaling is a common immune defect in human cancer. Proceedings of the National Academy of Sciences. DOI: 10.1073/pnas.0901329106
The ability to interpret other peoples' emotions is vital for social interactions. We recognize emotions in others by observing their body language and facial expressions. The voice also betrays one's emotional state: words spoken in anger have a different rhythm, stress and intonation than those uttered with a sense of joy or relief. But how the emotional content of a voice is encoded in the brain was unclear.
Now though, Swiss researchers report that they have decoded the neural activity in t........ Read more »
Ethofer, T., Van De Ville, D., Scherer, K., & Vuilleumier, P. (2009) Decoding of Emotional Information in Voice-Sensitive Cortices. Current Biology. DOI: 10.1016/j.cub.2009.04.054
If, like me, you grew up in the U.S. in the 1970s and 80s, you probably remember the game show Name That Tune, where contestants heard brief snippets from popular songs and had to name them as quickly as possible. Even though I didn't know most of the music, which was primarily American Standards from the 30s, 40s, and 50s, I still found the show fascinating. My favorite part of the game was when the two contestants engaged in a bidding war, where a clue was given and the contestants bet on how ........ Read more »
Peynircioglu, Z., Rabinovitz, B., & Thompson, J. (2007) Memory and metamemory for songs: the relative effectiveness of titles, lyrics, and melodies as cues for each other. Psychology of Music, 36(1), 47-61. DOI: 10.1177/0305735607079722
David Smith (University of York, United Kingdom)
and coworkers have synthesized polymers that form strong
chemical bonds with DNA, yet degrade over time, which enhances
their utility as possible DNA delivery vehicles for gene therapy.
This news feature was written on May 18, 2009.... Read more »
Welsh, D. J., Jones, S. P., & Smith, D. K. (2009) “On-Off” Multivalent Recognition: Degradable Dendrons for Temporary High-Affinity DNA Binding. Angewandte Chemie International Edition, 48(22), 4047-4051. DOI: 10.1002/anie.200900401
I read an interesting paper today from PLoS ONE that was published in July 2007. It is more along the lines of physiology than it is about anthropology, or dental anthropology for that matter, but nevertheless, it has implications for anthropologists. Not the mention that the title of the paper is "Stable Isotope Ratios in Hair and Teeth Reflect Biologic Rhythms", so of course, I had to read it. The aim of the paper was to use stable isotope hydrogen in hair and stable isotopes carbon and oxygen........ Read more »
Appenzeller, O., Qualls, C., Barbic, F., Furlan, R., & Porta, A. (2007) Stable Isotope Ratios in Hair and Teeth Reflect Biologic Rhythms. PLoS ONE, 2(7). DOI: 10.1371/journal.pone.0000636
I thought it worth spending a little time considering goals because so many of us work to help people generate goals – but how many are completed? I’m sure I could lay money on the table that most of us have failed to persist with a goal when we’ve set one, and it’s no [...]... Read more »
Ziegelmann, J., Luszczynska, A., Lippke, S., & Schwarzer, R. (2007) Are goal intentions or implementation intentions better predictors of health behavior? A longitudinal study in orthopedic rehabilitation. Rehabilitation Psychology, 52(1), 97-102. DOI: 10.1037/0090-5522.214.171.124
Lots of people have been analyzing the new H1N1 influenza virus by sequence analysis, comparing to influenza sequences in various databases (I used the NCBI’s). How reliable are these databases?
Our observations show that a fraction of the sequences in the database exhibit anomalous properties that point to either radically new biology or, more likely, problems [...]... Read more »
Krasnitz, M., Levine, A., & Rabadan, R. (2008) Anomalies in the Influenza Virus Genome Database: New Biology or Laboratory Errors?. Journal of Virology, 82(17), 8947-8950. DOI: 10.1128/JVI.00101-08
The largest population of leatherback sea turtles in the world has been identified off the coast of Gabon, Africa, and is estimated at somewhere between 15,700 and 41,400 female turtles. This seems to be a big bounceback for the endangered turtles, which are the largest living members of the sea turtle superfamily.
This rough estimate was [...]... Read more »
Witt, M., Baert, B., Broderick, A., Formia, A., Fretey, J., Gibudi, A., Moussounda, C., Mounguengui Mounguengui, G., Ngouessono, S., & Parnell, R. (2009) Aerial surveying of the world’s largest leatherback turtle rookery: A more effective methodology for large-scale monitoring. Biological Conservation. DOI: 10.1016/j.biocon.2009.03.009
by Nestor Lopez-Duran PhD in Child-Psych
It is fascinating that infant movements can serve as a window into their developing brain. Numerous studies have shown that the quality of infant movements, especially among premature babies, strongly predicts whether the infant will have motor and neurological problems. The basic idea is that in normal development, infants move in very predictable ways, such [...]... Read more »
Butcher, P., van Braeckel, K., Bouma, A., Einspieler, C., Stremmelaar, E., & Bos, A. (2009) The quality of preterm infants’ spontaneous movements: an early indicator of intelligence and behaviour at school age. Journal of Child Psychology and Psychiatry. DOI: 10.1111/j.1469-7610.2009.02066.x
It's good news though! A description of the tactics and appropriate response to denialism was published in the European Journal of Public Health by authors Pascal Diethelm and Martin McKee. It's entitled "Denialism: what is it and how should scientists respond?" and I think it does an excellent job explaining the harms of deniailsm, critical elements of denialism, as well as providing interesting historical examples of corporate denialism on the part of tobacco companies.
HIV does not cause A........ Read more »
Diethelm, P., & McKee, M. (2008) Denialism: what is it and how should scientists respond?. The European Journal of Public Health, 19(1), 2-4. DOI: 10.1093/eurpub/ckn139
In 1998, one of the most influential publications of the last 2 decades was published on treatment of the patellofemoral joint. Four of the leaders and pioneers of sports medicine and orthopedic rehabilitation – Kevin Wilk, George Davies, Bob Mangine, and Terry Malone - teamed up to develop a classification system for the differential diagnosis of patellofemoral pathologies. This manuscript was the first to offer treatment strategies based on specific diagnoses for patellofemoral p........ Read more »
Wilk KE, Davies GJ, Mangine RE, Malone TR. (1998) Patellofemoral disorders: a classification system and clinical guidelines for nonoperative rehabilitation. JOSPT. DOI: 9809279
In the recent numbers of British Journal of General Practice articles were published about depression in General Practice. In The Netherlands about 80% of patients with a depression visit the GP. In The Netherlands it’s estimated that in 2003 about 856.000 people in a year suffer from depression. That’s 6.3% on a population of 16 [...]... Read more »
Boardman, J., & Walters, P. (2009) Managing depression in primary care: it's not only what you do it's the way that you do it. British Journal of General Practice, 59(559), 76-78. DOI: 10.3399/bjgp09X395049
van Geffen, E., Gardarsdottir, H., van Hulten, R., van Dijk, L., Egberts, A., & Heerdink, E. (2009) Initiation of antidepressant therapy: do patients follow the GP's prescription?. British Journal of General Practice, 59(559), 81-87. DOI: 10.3399/bjgp09X395067
Cuijpers, P., van Straten, A., van Schaik, A., & Andersson, G. (2009) Psychological treatment of depression in primary care: a meta-analysis. British Journal of General Practice, 59(559), 51-60. DOI: 10.3399/bjgp09X395139
Kendrick, T., Dowrick, C., McBride, A., Howe, A., Clarke, P., Maisey, S., Moore, M., & Smith, P. (2009) Management of depression in UK general practice in relation to scores on depression severity questionnaires: analysis of medical record data. BMJ, 338(mar19 1). DOI: 10.1136/bmj.b750
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