With the rapid expansion of next-generation sequencing, there has been speculation that the backbone technology of older genomic sequencing, large-insert cloning (e.g., using bacterial artificial chromosomes [BACs]) would become less important. However, in many laboratories, BAC libraries still play a role in sequencing and gene expression studies.
In a recent study, Okada et al. screened a library created in the CopyControl™ BAC Cloning Kit (Hind III cloning-ready vector) to study the mechan........ Read more »
Okada, K. et al. (2010) Related polymorphic F-box protein genes between haplotypes clustering in the BAC contig sequences around the S-RNase of Japanese pear. Journal of Experimental Botany. DOI: 10.1093/jxb/erq381
I’ve mentioned Graphene a few times in the blog and I wanted to spend some time explaining what sort of things people are doing with it, why it’s worthy of a Nobel Prize, and why it’s just plain cool! In fact, check out this picture: Read more below for additional reasons why graphene is awesome… [...]... Read more »
Novoselov, K. (2004) Electric Field Effect in Atomically Thin Carbon Films. Science, 306(5696), 666-669. DOI: 10.1126/science.1102896
Bae, S., Kim, H., Lee, Y., Xu, X., Park, J., Zheng, Y., Balakrishnan, J., Lei, T., Ri Kim, H., Song, Y.... (2010) Roll-to-roll production of 30-inch graphene films for transparent electrodes. Nature Nanotechnology, 5(8), 574-578. DOI: 10.1038/nnano.2010.132
Seol, J., Jo, I., Moore, A., Lindsay, L., Aitken, Z., Pettes, M., Li, X., Yao, Z., Huang, R., Broido, D.... (2010) Two-Dimensional Phonon Transport in Supported Graphene. Science, 328(5975), 213-216. DOI: 10.1126/science.1184014
Lin, Y., Dimitrakopoulos, C., Jenkins, K., Farmer, D., Chiu, H., Grill, A., & Avouris, P. (2010) 100-GHz Transistors from Wafer-Scale Epitaxial Graphene. Science, 327(5966), 662-662. DOI: 10.1126/science.1184289
I’m pleased to announce that the Fall 2010 issue of NISO‘s International Standards Quarterly (ISQ) is done and available online to NISO members and ISQ subscribers. Print copies are scheduled to be mailed on December 28th. The individual issue is available for purchase (see the form link to on the issue homepage), and some of [...]Post from: Disruptive Library Technology Jester“Do More … With Someone Else” — Guest Editor Introduction to NISO ISQ Fall Issue ... Read more »
Murray, Peter E. (2010) Do More .. With Someone Else. International Standards Quarterly, 22(4), 3-3. info:/10.3789/isqv22n4.2010.01
When you are having a bad day, often you want support from your friends–but at the same time you just want to be left alone. New research published in Psychological ... Read more »
Howland, M., & Simpson, J.A. (2010) Getting in Under the Radar: A Dyadic View of Invisible Support. Psychological Science : a journal of the Association for Psychological Science/ APS. PMID: 21097721
This week a video entry with a clip of the Dutch tv program Vrije Geluiden: Last Sunday prof. Erik Scherder (Free University Amsterdam) explained some recent research (by, e.g., Hyde et al., 2009) on the influence of music performance and music listening on brain plasticity. The full episode can be viewed here (N.B. no subtitles).Hyde, K., Lerch, J., Norton, A., Forgeard, M., Winner, E., Evans, A., & Schlaug, G. (2009). Musical Training Shapes Structural Brain Development Journal of Neurosci........ Read more »
Hyde, K., Lerch, J., Norton, A., Forgeard, M., Winner, E., Evans, A., & Schlaug, G. (2009) Musical Training Shapes Structural Brain Development. Journal of Neuroscience, 29(10), 3019-3025. DOI: 10.1523/JNEUROSCI.5118-08.2009
It's only a couple of weeks since my massive coverage of video games research, but another interesting article has come up on the topic. This time - an exploration of personality as it can be used to explain attraction to violent video games.... Read more »
Chory, R., & Goodboy, A. (2010) Is Basic Personality Related to Violent and Non-Violent Video Game Play and Preferences?. Cyberpsychology, Behavior, and Social Networking, 2147483647. DOI: 10.1089/cyber.2010.0076
So, picture this: you’re at a friend’s holiday party, full of good cheer. Maybe you have a drink in hand, you’re laughing and catching up with people, swinging regularly by the candlelit dining room table, which is overflowing with the most glorious food: cheeses you can’t pronounce, fancy little appetizers nestled in puff pastry, shrimp [...]... Read more »
Yanovski, J., Yanovski, S., Sovik, K., Nguyen, T., O'Neil, P., & Sebring, N. (2000) A Prospective Study of Holiday Weight Gain. New England Journal of Medicine, 342(12), 861-867. DOI: 10.1056/NEJM200003233421206
For humans, sleep deprivation has a negative impact on performance in many areas, such as motor and communication skills. In particular, communication impairment is the topic of an article published yesterday in . But the research in this paper isn’t … Continue reading →... Read more »
Barrett A. Klein, Arno Klein, Margaret K. Wray, Ulrich G. Mueller, Thomas D. Seeley. (2010) Sleep deprivation impairs precision of waggle dance signaling in honey bees. Proceedings of the National Academy of Sciences. info:/10.1073/pnas.1009439108
Today I’m delighted to announce that we have a guest post from Adam Bristol, Ph.D, who works for Aquilo Capital Management in San Francisco. Adam helps to manage a life sciences investment fund, where they invest in new drug discovery … Continue reading →... Read more »
Komarov PG, Komarova EA, Kondratov RV, Christov-Tselkov K, Coon JS, Chernov MV, & Gudkov AV. (1999) A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy. Science (New York, N.Y.), 285(5434), 1733-7. PMID: 10481009
Maclean, K., Dorsey, F., Cleveland, J., & Kastan, M. (2008) Targeting lysosomal degradation induces p53-dependent cell death and prevents cancer in mouse models of lymphomagenesis. Journal of Clinical Investigation, 118(1), 79-88. DOI: 10.1172/JCI33700
One of the suggested ways to address weight-bias and discrimination amongst health professionals could be to teach medical students more about the genetic determinants of excess weight.
But will this really reduce weight bias?
This question was now addressed by Persky and Eccleston from the US National Institutes of Health in a study just published in the [...]... Read more »
Persky S, & Eccleston CP. (2010) Impact of Genetic Causal Information on Medical Students' Clinical Encounters with an Obese Virtual Patient: Health Promotion and Social Stigma. Annals of behavioral medicine : a publication of the Society of Behavioral Medicine. PMID: 21136226
by Rita Handrich in The Jury Room
In 1992, Sade sang ‘Smooth Operator’. Almost two decades later we have research confirming that a smooth talker wins the day still. Put more bluntly—style trumps substance (particularly when that substance is delivered poorly). We say we want information, but really we want infotainment. Todd Rogers and Michael Norton (both at Harvard) showed participants different [...]
Related posts:Questions, rabbit trails and how to know when a bear is “disturbed”
When identifying punishment—........ Read more »
With the advance of nanomedicine, bio-nanotechnology, and molecular biology, researchers require tools that allow them to work on a single cell level. These tools are required to probe individual cells, monitor their processes, and control/alter their functions through nanosurgery procedures and injection of drugs, DNA etc. - all without damaging the cells, of course. Researchers have now developed a multifunctional endoscope-like device, using individual CNTs for prolonged intracellular probing........ Read more »
Singhal, R., Orynbayeva, Z., Kalyana Sundaram, R., Niu, J., Bhattacharyya, S., Vitol, E., Schrlau, M., Papazoglou, E., Friedman, G., & Gogotsi, Y. (2010) Multifunctional carbon-nanotube cellular endoscopes. Nature Nanotechnology. DOI: 10.1038/nnano.2010.241
Psychologists investigating two (non-BP) deep-water, offshore oil rigs in the Gulf of Mexico have applauded the working-practices they observed, claiming they allowed the predominantly male workforce to 'undo' gender - that is, to stop pursuing a counter-productive, masculine ideal.
Setting the scene in their new paper, Robin Ely and Debra Meyerson argue that dangerous work-places have traditionally encouraged male staff to 'do gender' by demonstrating physical prowess, taking risks, conc........ Read more »
Ely, R., & Meyerson, D. (2010) An organizational approach to undoing gender: The unlikely case of offshore oil platforms. Research in Organizational Behavior, 3-34. DOI: 10.1016/j.riob.2010.09.002
[Wherein our Hero looks at what research has most influenced him. A story to be continued...]As with most of these monthly themes, I'm at a loss. I'm still an undergrad, and am yet to be afforded the luxury of independent thought. I'm yet to commence honours, and further still from a PhD. I have a vague inkling of a preference towards a vast area of psychology, but what I would like; (read more)
Source: Rift - Discipline: Psychology... Read more »
I tweeted this link all over the internets the other day, and not surprisingly, it got picked up a lot. And why not? Free will is one of those subjects that is particularly interesting to, well, just about everyone. It’s one the deep philosophical questions pondered by philosophers, and high people everywhere: DO we really [...]... Read more »
Pronin, E., & Kugler, M. (2010) People believe they have more free will than others. Proceedings of the National Academy of Sciences. DOI: 10.1073/pnas.1012046108
When in Rome…Learn why the Romans do what they do: how multicultural learning experiences facilitate creativity From Personality and Social Psychology Bulletin This research reveals that creativity can be enhanced by experiencing cultures different from one’s own. Three studies looked at students who had lived abroad and those who hadn’t, testing them on [...]... Read more »
Maddux, W., Adam, H., & Galinsky, A. (2010) When in Rome .. Learn Why the Romans Do What They Do: How Multicultural Learning Experiences Facilitate Creativity. Personality and Social Psychology Bulletin, 36(6), 731-741. DOI: 10.1177/0146167210367786
Students have different thinking styles. The way students think, perceive and remember information, or their preferred approach to using such information to solve problems can be different between students. Different models for learning styles are present. The mostly used is the learning style model by Kolb. Students have preferred learning styles as well as lecturers [...]
Related posts:What Kind of a Person Blogs
Speciality Choice of Medical Students, Impact of Clerkship
What Kind of a Pers........ Read more »
SWAMI, V., FURNHAM, A., MAAKIP, I., AHMAD, S., HUDANI, N., VOO, P., CHRISTOPHER, A., & GARWOOD, J. (2007) A cross-cultural investigation of students' preferences for lecturers' personalities in Britain, Malaysia and the United States. Learning and Individual Differences, 17(4), 307-315. DOI: 10.1016/j.lindif.2007.03.006
microRNAs have become a rich source of research as they probably have a huge effect on gene expression and disease. The human genome may encode over 1,000 miRNAs that target over half of our genes. They might be implicated in a lot of common diseases (which not yet have been picked up in GWAS studies?). They are a fascinating area of biology that has only come of it’s on in the last decade. As such, the number of databases to catalog miRNAs is large. Today’s tip is on a new one, RepT........ Read more »
Elefant, N., Berger, A., Shein, H., Hofree, M., Margalit, H., & Altuvia, Y. (2010) RepTar: a database of predicted cellular targets of host and viral miRNAs. Nucleic Acids Research. DOI: 10.1093/nar/gkq1233
Michelle tipped me off to yet another "all the bees are dying" article.
The new wrinkle in the story is a leaked EPA memo that suggests that Bayer CropScience's seed treatment, chlothianidin, was registered without sufficient proof that it didn't hurt bees. Aside from the fact that this registration was completed in 2004 and (according to the same article) this whole bee business started in the mid-1990s, I'm skeptical that any new pesticide is causing all this. We were SO much more indiscrimin........ Read more »
John M. Skelly, & John L. Innes. (1994) Waldsterben in the Forests of Central Europe and Eastern North America: Fantasy or Reality?. Plant Disease, 78(11), 1021-1032. info:/
If you wrote to the organising committee of a scientific conference saying that you have a theory that there is a person in everyone’s bum and if you massage it in the...... Read more »
Do you write about peer-reviewed research in your blog? Use ResearchBlogging.org to make it easy for your readers — and others from around the world — to find your serious posts about academic research.
If you don't have a blog, you can still use our site to learn about fascinating developments in cutting-edge research from around the world.
Research Blogging is powered by SMG Technology.
To learn more, visit seedmediagroup.com.