With the national push toward electronic medical records, there have been active efforts to upgrade clinical data and systems software. At some institutions, an effect of this transition is the migration from the traditional voice dictation systems or paper clinic notes to a typed electronic record.
A recent study at the University of Toronto Faculty [...]
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Maslove DM, Leiter RE, Griesman J, Arnott C, Mourad O, Chow CM, & Bell CM. (2009) Electronic Versus Dictated Hospital Discharge Summaries: a Randomized Controlled Trial. Journal of general internal medicine. PMID: 19609623
We have come to expect the unexpected of ciliates, and Oxytricha trifallax, with its genomic capers, does not disappoint. Like many of its more famous ciliate relatives (e.g., paramecium, tetrahymena, stentor), Oxytricha is a complex unicellular organism with many specialized cellular structures. Of course, they have the requisite cilia for locomotion, feeding, and sensing their environment. But they also have a "mouth," food vacuoles where digestion takes place, kidney-like contractile vacuoles........ Read more »
Nowacki, M., Vijayan, V., Zhou, Y., Schotanus, K., Doak, T., & Landweber, L. (2007) RNA-mediated epigenetic programming of a genome-rearrangement pathway. Nature, 451(7175), 153-158. DOI: 10.1038/nature06452
Nowacki, M., Higgins, B., Maquilan, G., Swart, E., Doak, T., & Landweber, L. (2009) A Functional Role for Transposases in a Large Eukaryotic Genome. Science, 324(5929), 935-938. DOI: 10.1126/science.1170023
by Vincent Racaniello in virology blog
Recently while driving north on the New York State Thruway I passed the exit for the town of Coxsackie, NY (population 8,884). I grabbed my camera and photographed the exit sign, and reminded myself to write about the virus named after this small town.
In the summer of 1947 there were several small outbreaks of poliomyelitis [...]... Read more »
Dalldorf G, & Sickles GM. (1948) An Unidentified, Filtrable Agent Isolated From the Feces of Children With Paralysis. Science (New York, N.Y.), 108(2794), 61-62. PMID: 17777513
The old adage, “sticks and stones may break my bones, but words will never hurt me,” may be more defensive than accurate. Indeed, most languages rely on words that represent pain — hurt feelings, heartache, broken hearts — to communicate feelings of social distress. Recent findings in neuroscience suggest that sayings such as these may [...]... Read more »
Eisenberger, N. (2003) Does Rejection Hurt? An fMRI Study of Social Exclusion. Science, 302(5643), 290-292. DOI: 10.1126/science.1089134
Hadland, K. (2003) The effect of cingulate lesions on social behaviour and emotion. Neuropsychologia, 41(8), 919-931. DOI: 10.1016/S0028-3932(02)00325-1
This was a stunner via a tweet from the Roswell Park Cancer Institute yesterday. Of course, I clicked on the link because my suspicion was that it wouldn't be the most common O blood that is linked to pancreatic cancer,...... Read more »
Amundadottir, L., Kraft, P., Stolzenberg-Solomon, R., Fuchs, C., Petersen, G., Arslan, A., Bueno-de-Mesquita, H., Gross, M., Helzlsouer, K., Jacobs, E.... (2009) Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer. Nature Genetics. DOI: 10.1038/ng.429
Planning a new city, mapping out a town redevelopment, or simply coming up with a blueprint for an eco site? Matthew Carmona, Professor of Planning & Urban Design at the Bartlett School of Planning, University College London, has ten questions you must answer honestly before digging the first foundations and routing the roads if you [...]Ten questions to answer before building your eco-town is a post from: Sciencebase Science Blog
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Someone here wanted Ebriids and Ellobiopsids. Since I'm still in a bit of Rhizarian mood, let's do Ebriids first. Just as you thought we couldn't get any more obscure than Phaeodaria...Ebriids are biflagellate Cercozoans (see the Pawlowski & Burki 2009 Rhizaria tree in the Coelodiceras post for their phylogenetic neighbourhood) with a characteristic silica endoskeleton, permanently condensed nuclear chromatin and lack of cell wall or scales. They are rare and still unculturable, so very litt........ Read more »
Hoppenrath, M., & Leander, B. (2006) Ebriid Phylogeny and the Expansion of the Cercozoa. Protist, 157(3), 279-290. DOI: 10.1016/j.protis.2006.03.002
Hargraves, P.E. (2002) The ebridian flagellates Ebria and Hermesinum. Plankton Biology and Ecology, 49(1), 9-16. info:/
Korhola, A., & Grönlund, T. (1999) Observations of Ebria tripartita (Schumann) Lemmermann in Baltic sediments. Journal of Paleolimnology, 21(1), 1-8. DOI: 10.1023/A:1008019504122
While Health Canada continues to ignore its own task force's recommendations to ban trans-fats, New York is off an running.A recent report published in the Annals of Internal Medicine revealed that since their regulation in 2006 98% of restaurants are trans-fat free and that it has been a "cost neutral" shift.What's more interesting is that preliminary studies suggest that while indeed the shift from trans-fats have increased the use of saturated fats, it also increased the use of unsaturated fa........ Read more »
Angell SY, Silver LD, Goldstein GP, Johnson CM, Deitcher DR, Frieden TR, Bassett MT. (2009) Cholesterol control beyond the clinic: New York City's trans fat restriction. Annals of Internal Medicine, 151(2), 129-134. DOI: 19620165
Slightly tangential to my normal topics, I located this article today on a placebo procedure that may work for acupuncture.
Many people will be aware that in acupuncture, it’s really difficult to truly conduct a double-blind trial where both the person receiving and the person giving the treatment are unaware of which is the ‘active’ treatment. [...]... Read more »
Miyazaki S, Hagihara A, Kanda R, Mukaino Y, & Nobutomo K. (2009) Applicability of press needles to a double-blind trial: a randomized, double-blind, placebo-controlled trial. The Clinical journal of pain, 25(5), 438-44. PMID: 19454879
A recent study by Goodrich-Hunsaker and Hopkins showed that amnesic patients with hippocampal damage performed above the recommended cutoff scores on immediate and delayed recognition of the Word Memory Test (WMT), but were significantly impaired on the multiple-choice, paired associate, and free-recall subtests. The authors suggest that the hippocampal damage may be the culprit for such impairment. So how do they explain the above cutoff scores on the immediate and delayed recognition subtests?........ Read more »
Goodrich-Hunsaker NJ, & Hopkins RO. (2009) Word memory test performance in amnesic patients with hippocampal damage. Neuropsychology, 23(4), 529-34. PMID: 19586216
An interesting study by Xu et al. over at Peking University has further demonstrated an aspect of evolutionary development that we are trying so hard to escape in the present day world. Racial exclusion, especially when it comes to empathy, can negatively impact our attitudes and behaviors towards outgroups whether we're aware of it or not. Here is their abstract.The pain matrix including the anterior cingulate cortex (ACC) mediates not only first person pain experience but also empathy for othe........ Read more »
Xu X, Zuo X, Wang X, & Han S. (2009) Do you feel my pain? Racial group membership modulates empathic neural responses. The Journal of neuroscience : the official journal of the Society for Neuroscience, 29(26), 8525-9. PMID: 19571143
Very cool study by Karlsson and Frank showing that rats' reactivate stored representations of remote experiences during waking replay in the hippocampus. But why is it only with remote rather than local replay? They suggest that novel experiences may play a role in which long lasting neuronal excitability and coordination for the cells during those experiences are generated.In the discussions section they make mention of the probable dysynchronized neocortical state during awake replay constrast........ Read more »
Karlsson MP, & Frank LM. (2009) Awake replay of remote experiences in the hippocampus. Nature neuroscience, 12(7), 913-8. PMID: 19525943
Stress typically indicates a demand to adapt to challenges found in everyday life. However, when the stress is uncontrollable, unpredictable, and chronic it can increase the brain's vulnerability to disease.Dagyte et al. over at the University of Groningen investigated the effects of acute and chronic foot-shock stress on neural plasticity by using hippocampal cell proliferation and neurogenesis data collected from rats. They found that repeated, but not acute exposure to foot-shock stress cause........ Read more »
Dagyte G, Van der Zee EA, Postema F, Luiten PG, Den Boer JA, Trentani A, & Meerlo P. (2009) Chronic but not acute foot-shock stress leads to temporary suppression of cell proliferation in rat hippocampus. Neuroscience, 162(4), 904-13. PMID: 19482059
Audiences differ. Talk to one person and your words are welcomed by a smile and nod of acknowledgment. Speak to another, less winsome listener and your words are confronted by a frown and folded arms. According to Camiel Beukeboom, these different responses systematically alter your use of language. Speak to a positive listener and you'll likely use more abstractions and subjective impressions, whilst if you talk to a negative listener you'll probably find yourself sheltering in the security of ........ Read more »
Beukeboom, C. (2009) When words feel right: How affective expressions of listeners change a speaker's language use. European Journal of Social Psychology, 39(5), 747-756. DOI: 10.1002/ejsp.572
In a paper which shows that women in Chile raised in a non-religious environment are less likely to be a victim of so called 'intimate partner' violence, the authors conclude that there is evidence that a moderate dose of religion actually protects against it! How can that be? And, more importantly, are they right? Let me take you on a short journey into the dark side of statistics...'Cross-sectional' studies are ones that measure a whole bunch of stats about a group of people, and then see whic........ Read more »
Lehrer, E., Lehrer, V., & Krauss, R. (2009) Religion and intimate partner violence in Chile: Macro- and micro-level influences. Social Science Research, 38(3), 635-643. DOI: 10.1016/j.ssresearch.2009.03.001
Rees, TJ. (2009) Is Personal Insecurity a Cause of Cross-National Differences in the Intensity of Religious Belief?. Journal of Religion and Society. DOI: http://moses.creighton.edu/JRS/2009/2009-17.html
Pollen is key to letting plants live on land. It packages up plants’ sperm so that wind or animals can transport them to the female part of a plant, without requiring water. Ferns, which don’t have pollen, can only grow where there’s enough moisture for sperm to swim to meet eggs.
Before pollen is released, it’s [...]... Read more »
Mao, Y., & Huang, S. (2009) Pollen resistance to water in 80 angiosperm species: flower structures protect rain-susceptible pollen. New Phytologist, 183(3), 892-899. DOI: 10.1111/j.1469-8137.2009.02925.x
Paul de Figueiredo, Arum Han, and coworkers at Texan A and M University have improved the prospects of harvesting bacteria for energy production. This news feature was written on August 9, 2009.... Read more »
Hou, H., Li, L., Cho, Y., de Figueiredo, P., & Han, A. (2009) Microfabricated Microbial Fuel Cell Arrays Reveal Electrochemically Active Microbes. PLoS ONE, 4(8). DOI: 10.1371/journal.pone.0006570
A study conducted by Popescu, Popa, and Pare investigated the underlying mechanism driving amygdalostriatal interactions during memory formation. The impetus for this study came from an interest in studies implicating the basolateral amygdala (BLA) activity in the facilitation of striatal-dependent memories in emotional arousal. They measured unit and local field potential recordings from the BLA, striatum, auditory cortex, and intralaminar thalamus of cats trained on a stimulus-response task w........ Read more »
Popescu AT, Popa D, & Paré D. (2009) Coherent gamma oscillations couple the amygdala and striatum during learning. Nature neuroscience. PMID: 19430471
Sybil Geldart (2008) has found that taller people prefer faces with longer foreheads and shorter people prefer faces with longer chins. She had subjects place facial features (brows, eyes, nose, and mouth) inside the outlines of their respective faces, and found that taller subjects placed the features lower in the face while shorter subjects placed [...]... Read more »
Robert Linhardt (Rensselaer Polytechnic Institute, New York) and coworkers have developed a small-scale device that can be utilized to probe the function of cellular enzymes, rapidly and in parallel. This news feature was written on August 8, 2009.... Read more »
Martin, J. G., Gupta, M., Xu, Y., Akella, S., Liu, J., Dordick, J. S., & Linhardt, R. J. (2009) Toward an Artificial Golgi: Redesigning the Biological Activities of Heparan Sulfate on a Digital Microfluidic Chip. Journal of the American Chemical Society, 131(31), 11041-11048. DOI: 10.1021/ja903038d
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