Post List

  • November 29, 2010
  • 09:51 AM

how to navigate in deep space with dead stars

by Greg Fish in weird things

Not only are GPS devices useful, they’re also an ongoing experiment that keeps confirming special relativity’s spot on descriptions of how time flows for fast-moving objects. Without constant adjustments, GPS would be quickly rendered unusable because accurate timing of the signals being sent between the satellites and the moving object they’re supposed to track is [...]... Read more »

Angelo Tartaglia, Matteo Luca Ruggiero, & Emiliano Capolongo. (2010) A null frame for spacetime positioning by means of pulsating sources. Advances in Space Research. arXiv: 1001.1068v3

  • November 29, 2010
  • 09:48 AM

Level of Detail in a Simulation Model

by Daniel Dumke in SCRM Blog - Supply Chain Risk Management

After the last more general entries on managers perception of risk and measuring SC performance I wanted to make a detour back to the basics.
Simulation is one of the tools, which can be used for analyzing supply chain dynamics, optimization and to support corporate decision making.
One major question when starting a supply chain model has always been what level of detail should you choose? Someone could start with a single worker in an agent based simulation model and continue with the mac........ Read more »

  • November 29, 2010
  • 08:00 AM

How Obesity Promotes Breast Cancer

by Arya M. Sharma in Dr. Sharma's Obesity Notes

Regular readers of these pages are probably well aware of the increasing data on the importance of obesity as a risk factor for cancers.
This is particularly true for hormone-sensitive cancers like post-menopausal breast and ovarian cancer, which are significantly more common in women with excess weight. In addition, excess weight appears to negatively affect the [...]... Read more »

Di LJ, Fernandez AG, De Siervi A, Longo DL, & Gardner K. (2010) Transcriptional regulation of BRCA1 expression by a metabolic switch. Nature structural . PMID: 21102443  

  • November 29, 2010
  • 07:07 AM

Dinosaurs and Other Extinct Saurians: A Historical Perspective, the book

by Darren Naish in Tetrapod Zoology

As you'll know if you have your fingers on the throbbing pulse of dinosaur-related publications, the massive, incredibly pricey volume published by the Geological Society of London, and resulting from the 2008 meeting History of Dinosaurs and Other Fossil Saurians, now exists in dead-tree form. It's titled Dinosaurs and Other Extinct Saurians: A Historical Perspective and (in my totally unbiased opinion) is a definite must-see* for anyone interested in the historical side of Mesozoic reptile........ Read more »

  • November 29, 2010
  • 07:00 AM

November 29, 2010

by Erin Campbell in HighMag Blog

Basic research is fundamental if we want to make strides in understanding disease. Please (politely) shout this from the mountaintops and make sure your lawmakers and funding agencies understand this. Today’s image is from a paper that investigates a key player in cell scattering, which is an event very similar to cancer metastasis. Cell scattering is a term used to describe cell-cell dissociation and migration and occurs in liver development, organ regeneration, and metastasis. Cell sc........ Read more »

  • November 29, 2010
  • 06:00 AM

Pros and Cons of Social Media Use in Medicine

by Michelle Lin in Academic Life In Emergency Medicine

The American Medical Association (AMA) just released a policy on Social Media and Medical Professionalism. It focuses more on the negative aspects of social media, and much can be averted by just by using common sense:Physicians should weigh a number of considerations when maintaining a presence online:Physicians should be cognizant of standards of patient privacy and confidentiality that must be maintained in all environments, including online, and must refrain from posting identifiable patient........ Read more »

Greysen SR, Kind T, & Chretien KC. (2010) Online professionalism and the mirror of social media. Journal of general internal medicine, 25(11), 1227-9. PMID: 20632121  

  • November 29, 2010
  • 05:51 AM

New insights into Rett syndrome

by Kevin Mitchell in Wiring the Brain

A pair of papers from the lab of Fred Gage has provided new insights into the molecular and cellular processes affected in Rett syndrome. This syndrome is associated with arrested development and autistic features. It affects mainly girls, who typically show normal development until around age two, followed by a sudden and dramatic deterioration of function, regression of language skills and the emergence of autistic symptoms. It is caused mainly by mutations in the gene encoding MeCP2, which........ Read more »

Muotri AR, Marchetto MC, Coufal NG, Oefner R, Yeo G, Nakashima K, & Gage FH. (2010) L1 retrotransposition in neurons is modulated by MeCP2. Nature, 468(7322), 443-6. PMID: 21085180  

  • November 29, 2010
  • 05:33 AM

Can psychology help combat pseudoscience?

by BPS Research Digest in BPS Research Digest

From homeopathy to dodgy nutritional supplements, support for pseudoscience and quackery thrives on people believing falsely that one thing causes another, when in fact it doesn't. Meanwhile, psychologists study belief formation, and specifically illusions of control (see earlier), whereby people wrongly believe that they're controlling something when they're not. In a new paper, three psychologists at Deusto University in Bilbao argue that the psychological literature can be mined for ways........ Read more »

Matute, H., Yarritu, I., & Vadillo, M. (2010) Illusions of causality at the heart of pseudoscience. British Journal of Psychology. DOI: 10.1348/000712610X532210  

  • November 29, 2010
  • 01:48 AM

Social Media Use by Medical Students

by Dr Shock in Dr Shock MD PhD

Social software or the use of Internet (Web 2.0) for generating your own content, to connect with one another and to share and manage content with each other is used by young people. How do first year medical students use this social software? This could be important because these networks could become networks of learners [...]

Related posts:Social Media in Health and Medicine: Medlibs Round 2.7
The Risks of Online Social Networking for Students
Disclosure of substance use on social media we........ Read more »

  • November 29, 2010
  • 01:18 AM

How bacteria sort their lipoproteins (Lol!)

by Microbe Fan in Spirochetes Unwound

Bacterial lipoproteins are proteins with covalently-attached lipid molecules that anchor the protein to the cytoplasmic or outer membrane.  The lipid molecules are attached to the cysteine located at the amino terminus of the lipoprotein.  The lipoprotein's protein component, being hydrophilic (water-loving), sticks out from the membrane. Different bacterial lipoproteins participate in a variety of functions, including transport of molecules, stabilization of the cell wall, signal tran........ Read more »

  • November 28, 2010
  • 09:00 PM

Weekend Review: Sterile Inflammation

by Kevin Bonham in Food Matters

If you've ever rolled your ankle (as I have many times), you have a visceral knowledge of inflammation. Clinically, inflammation is the redness, swelling, heat and pain that's associated with injury. From an immunologist's perspective, it's the set of molecular events that get the immune system going. All of the clinical systems associated with inflammation are due to increased vascular permeability, which is just a fancy way of saying leaky blood vessels. Actually, "leaky" implies that it's unc........ Read more »

Chen GY, & Nuñez G. (2010) Sterile inflammation: sensing and reacting to damage. Nature reviews. Immunology, 10(12), 826-37. PMID: 21088683  

  • November 28, 2010
  • 07:54 PM

Gastric bypass and psoriasis????

by Maureen McCormick in GourMind

Hossler EW, Maroon MS, & Mowad CM (2010). Gastric bypass surgery improves psoriasis. Journal of the American Academy of Dermatology PMID: 20655127How could I not blog this article? What could possibly be the connection between gastric bypass and a skin disease?The authors - dermatologists - describe two cases of significant long-lasting improvement in psoriasis after weight loss from gastric bypass surgery. They point out that obesity has been thought to be a risk factor for psoriasis, and t........ Read more »

Hossler EW, Maroon MS, & Mowad CM. (2010) Gastric bypass surgery improves psoriasis. Journal of the American Academy of Dermatology. PMID: 20655127  

  • November 28, 2010
  • 06:11 PM

Imaging Theory of Mind Development: TED Saxe Presentation

by William Yates, M.D. in Brain Posts

Theory of Mind relates to the development of an ability to understand the thoughts and emotions of others.  fMRI has provided significant insight into the brain region (right parietal-temporal junction) associated with this ability.  Dr. Rebecca Saxe from MIT has been a leader in this research.  Posted above is her TED talk related to her research--it is about 16 minutes.  Posted below are my notes on the presentation:As scientist I am interested in how it's so easy to unders........ Read more »

  • November 28, 2010
  • 05:02 PM

Psycasm - Babushka Blog: A Meta-Blog on ResearchBlogging.

by Rift in Psycasm

[Wherein our Hero seeks to understand the benefits of both reading and writing blogs]How meta- of me. A blog about blogging. It was sure to happen, as surely as it has happened everywhere else.In my defence at least it’s a researchblogging article about blogging.I have to say that the decision to start a blog was one of unintended consequences, all positive, I assure you.I had two motivations in; (read more)

Source: Rift - Discipline: Psychology... Read more »

  • November 28, 2010
  • 04:06 PM

Can psychological management of fibromyalgia affect pain?

by Bronwyn Thompson in Healthskills: Skills for Healthy Living

When I’m working with someone who has chronic pain, from the outset I’m pretty straight-up that the treatments I offer don’t directly affect pain intensity.  It’s not my focus, and very often after the first session, I don’t even discuss pain – I’m more interested in what the person is doing! And for this focus, … Read more... Read more »

Glombiewski, J., Sawyer, A., Gutermann, J., Koenig, K., Rief, W., & Hofmann, S. (2010) Psychological treatments for fibromyalgia: A meta-analysis. Pain, 151(2), 280-295. DOI: 10.1016/j.pain.2010.06.011  

  • November 28, 2010
  • 06:38 AM

Bacterial comet tails

by Lab Rat in Lab Rat

I haven't worked very much with bacteria that infect humans. Most of my lab work has been done in the fields of either synthetic biology (which works with model organisms) or antibiotic production, which works on soil bacteria that produce the antibiotics. Human bacterial parasites therefore hold the fascination of the slightly exotic, not least because they sometimes do things like this:Figure from"Molecular Biology of the Cell, Fourth Edition"by Alberts et al.I've written before about some of ........ Read more »

  • November 28, 2010
  • 03:40 AM

Surgeons and civic-professionalism

by Bernt Lindtjorn in International Health Research

Surgery is often the only solution to prevent disabilities and death from conditions resulting from pregnancy related complications, surgical conditions (example acute abdomen), infections, traffic accidents, falls, burns, disasters, domestic violence, and congenital defects. Until recently, surgery was neglected as a developing country public health issue. Health officials, especially in the World Health organization and [...]... Read more »

Funk, L., Weiser, T., Berry, W., Lipsitz, S., Merry, A., Enright, A., Wilson, I., Dziekan, G., & Gawande, A. (2010) Global operating theatre distribution and pulse oximetry supply: an estimation from reported data. The Lancet, 376(9746), 1055-1061. DOI: 10.1016/S0140-6736(10)60392-3  

  • November 28, 2010
  • 03:08 AM

Missing AIDS Patients

by Bernt Lindtjorn in International Health Research

It is important for HIV infected patients to take their drugs regularly. Interruptions in treatment lead to viral strains that are resistant to the cheapest medications, and to higher rates of illness and death. Unfortunately, many AIDS patients do not come for their antiretroviral medications. Such patients are labelled as “lost to follow-up.” During the [...]... Read more »

  • November 28, 2010
  • 03:08 AM

Seizures Triggered by Strawberry Syrup

by The Neurocritic in The Neurocritic

Fig 1A (modified from Blauwblomme et al., 2010). Top: coronal and lateral representation of the stereotaxic implantation scheme. Bottom: reflex seizure showing ictal onset in the right insula and secondary spreading in the hippocampus.Reflex epilepsy is a rare neurological condition in which seizures are triggered by a specific type of sensory input (Xue & Ritaccio, 2006). The most common reflex seizures are induced by light, but other reported triggers have included reading, Mah-Jong, mus........ Read more »

Blauwblomme, T., Kahane, P., Minotti, L., Grouiller, F., Krainik, A., Vercueil, L., Chabardes, S., Hoffmann, D., & David, O. (2010) Multimodal imaging reveals the role of   activity in eating-reflex seizures. Journal of Neurology, Neurosurgery . DOI: 10.1136/jnnp.2010.212696  

  • November 27, 2010
  • 08:51 PM

Hybrid vigor and missing genes

by James in James and the Giant Corn

[...]... Read more »

Fu H, & Dooner HK. (2002) Intraspecific violation of genetic colinearity and its implications in maize. Proceedings of the National Academy of Sciences of the United States of America, 99(14), 9573-8. PMID: 12060715  

Lai J, Li Y, Messing J, & Dooner HK. (2005) Gene movement by Helitron transposons contributes to the haplotype variability of maize. Proceedings of the National Academy of Sciences of the United States of America, 102(25), 9068-73. PMID: 15951422  

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