Post List

  • July 18, 2010
  • 02:50 PM

Developing Sustainable Ski Resorts in the United States Rocky Mountains

by Michael Long in Phased

Jordan Silberman and Peter Rees (University of Delaware, United States) find that the towns with the geographical characteristics of the typical ski resort in the United States Rocky Mountains face substantial infrastructure and environmental challenges, if they wish to reinvent their economies by venturing into ski tourism. This news feature was written on July 18, 2010.... Read more »

  • July 18, 2010
  • 12:07 AM

Cherry Picking to Generalize ~ retrospective meta-power analysis using Cohen’s f^2 of NASA temp visualization

by apeescape in mind of a Markov chain

Previously, I plotted a grid of NASA GISS global temps in ggplot2 to show general trends by the brute force method. Here, I will again use the brute force method to do a simple power analysis on a portion of the data (data here). The general aim is to figure out what the minimum sample [...]... Read more »

Thomas, L. (1997) Retrospective Power Analysis. Conservation Biology, 11(1), 276-280. DOI: 10.1046/j.1523-1739.1997.96102.x  

  • July 17, 2010
  • 11:35 PM

Quasars in the very early universe

by Charles Daney in Science and Reason

Quasars are powered by the gravitational (potential) energy of their central supermassive black holes. However, their distinctive features – their extremely high luminosity in particular – are very dependent on characteristics of matter close to the black hole. Most supermassive black holes (SMBH), including those at the centers of the Milky Way and our close neighbor M31 (Andromeda), are responsible for fairly small amounts of radiation in any part of the electromagnetic spectrum. T........ Read more »

Jiang, L., Fan, X., Brandt, W., Carilli, C., Egami, E., Hines, D., Kurk, J., Richards, G., Shen, Y., Strauss, M.... (2010) Dust-free quasars in the early Universe. Nature, 464(7287), 380-383. DOI: 10.1038/nature08877  

  • July 17, 2010
  • 10:30 PM

Collaboration 2.0

by Aurametrix team in Health Technologies

Information technology is letting people around the world come together in unprecedented ways. Wikis, blogs and microblogs like twitter, crowdsourcing and crowd-task-solving sites continue to flatten the planet. Scientific innovation used to be a private endeavor, with very narrowly specialized scientists. The Internet changed some of this but there is plenty of room for improvement.... Read more »

Johnston SC, & Hauser SL. (2009) Crowdsourcing scientific innovation. Annals of neurology, 65(6). PMID: 19562693  

Wright MT, Roche B, von Unger H, Block M, & Gardner B. (2010) A call for an international collaboration on participatory research for health. Health promotion international, 25(1), 115-22. PMID: 19854843  

Marsh A, Carroll D, & Foggie R. (2010) Using collective intelligence to fine-tune public health policy. Studies in health technology and informatics, 13-8. PMID: 20543334  

Huss JW 3rd, Lindenbaum P, Martone M, Roberts D, Pizarro A, Valafar F, Hogenesch JB, & Su AI. (2010) The Gene Wiki: community intelligence applied to human gene annotation. Nucleic acids research, 38(Database issue). PMID: 19755503  

  • July 17, 2010
  • 05:41 PM

How are British kids doing these days?

by Tom Rees in Epiphenom

British society, like that of most industrialized nations, has gone through enormous changes in recent decades. But it's hard to get objective data on what the impact has been on the people living there.

Which is why I was interested to see a recent study by Stephen Collishaw, of Cardiff University, and colleagues. They compared data from two studies, one in 1986 and one in 2006, that asked adolescents (aged 16-17) about their state of mind. Whether they felt anxious, depressed, worried, irrita........ Read more »

  • July 17, 2010
  • 02:53 PM

How viruses hijack cellular transport systems

by Lab Rat in Lab Rat

Even in the world of the very small, there are significant differences in size. A eukaryote cell (i.e a human cell) for example is relatively big, in microscopic terms. Most other things that interact with the cell at the microscopic level, are far smaller than it, such as bateria, viruses and signalling molecules.A virus isn't much more than a small capsule of proteins with a little bit of DNA inside. Once it gets inside a eukaryote cell, it's very much in the position of a small child wanderin........ Read more »

Kerstin Radtke, Daniela Kieneke, André Wolfstein, Kathrin Michael, Walter Steffen, Tim Scholz, Axel Karger, Beate Sodeik. (2010) Plus- and Minus-End Directed Microtubule Motors Bind Simultaneously to Herpes Simplex Virus Capsids Using Different Inner Tegument Structures. PLoS Patholgens, 6(7). info:/e1000991

  • July 17, 2010
  • 12:47 PM

Across disciplines, what motivates or prevents faculty staff archiving?

by Christina Pikas in Christina's LIS Rant

This article is in early view at JASIST. It looks like it comes from the author's dissertation. It isn't terribly earth-shattering, but it's well done, it provides more evidence, and there are definitely some implications for library/IR manager practice. Here's the citation: Kim, J. (2010). Faculty self-archiving: Motivations and barriers Journal of the American Society for Information Science and Technology DOI: 10.1002/asi.21336 The author went through a complicated process to identify 1,5........ Read more »

Kim, J. (2010) Faculty self-archiving: Motivations and barriers. Journal of the American Society for Information Science and Technology. DOI: 10.1002/asi.21336  

  • July 17, 2010
  • 12:41 PM

Human health effects of oil spills and implications for the BP spill

by Ashartus in exposure/effect

A lot of the media (and scientific) attention to oil spills in the ocean focuses on the effects on marine ecosystems. The ecological effects, particularly in the short term, are undeniable – the pictures of oil-soaked birds are an obvious example. However, less attention is given to the potential effects on human health – both [...]... Read more »

Aguilera, F., Méndez, J., Pásaro, E., & Laffon, B. (2010) Review on the effects of exposure to spilled oils on human health. Journal of Applied Toxicology. DOI: 10.1002/jat.1521  

  • July 17, 2010
  • 09:00 AM

Rodent Saturday!

by EcoPhysioMichelle in C6-H12-O6 (old)

Now, for my contribution to Saturday’s rodent blog, I will tell you about a new mouse species of the South American Akodon genus that was described earlier this year by Braun and colleagues in New species of Akodon (Rodentia: Cricetidae: Sigmodontinae) from central Argentina.... Read more »

  • July 17, 2010
  • 07:40 AM

Running experiments on Twitter? Don’t forget the bug

by ---a in

There's nothing that error analysis wouldn't fix. But I prefer to sit here and ponder the epistemological ramifications of the way bugs are impacting the traditional way we make science...... Read more »

Scott A. Golder and Sarita Yardi. (2010) Structural Predictors of Tie Formation in Twitter: Transitivity and Mutuality. Proceedings of the Second IEEE International Conference on Social Computing. August 20-22, Minneapolis, MN. info:/

  • July 17, 2010
  • 04:46 AM

Pleasure or Pain?

by The Neurocritic in The Neurocritic

Robert Mapplethorpe - Untitled (Self Portrait)The previous post (Erotic or Disgusting?) covered a functional MRI experiment on the neural responses to erotic films in heterosexual and homosexual males (Zhang et al., 2010). Specifically, the study examined sexual arousal and disgust while the participants viewed various types of porn. Neuroimaging results were reported only for the stimuli deemed distasteful by each group, wherein the left ventromedial prefrontal cortex was more active for gay ........ Read more »

STARK, R., SCHIENLE, A., GIROD, C., WALTER, B., KIRSCH, P., BLECKER, C., OTT, U., SCHAFER, A., SAMMER, G., & ZIMMERMANN, M. (2005) Erotic and disgust-inducing pictures—Differences in the hemodynamic responses of the brain. Biological Psychology, 70(1), 19-29. DOI: 10.1016/j.biopsycho.2004.11.014  

  • July 17, 2010
  • 12:03 AM

P. aeruginosa, Biofilms and Honey

by James Byrne in Disease Prone

A biofilm is generally described as a ‘synthesised environment housing a bacterial community on a surface’. This essentially means that organisms (not just bacteria) start to produce huge amount of ‘muck’ containing proteins, sugars and DNA and export it from the cell once bound to a ‘surface’. When it does this it generates its own little environmental niche and as that bacterial cell divides within the biofilm it can pool its resources allowing easier growth........ Read more »

PITTET, B., MONTANDON, D., & PITTET, D. (2005) Infection in breast implants. The Lancet Infectious Diseases, 5(2), 94-106. DOI: 10.1016/S1473-3099(05)01281-8  

  • July 16, 2010
  • 08:06 PM

Which came first, the scientist or the sensationalist?

by Casey Rentz in The Lay Scientist

The best headline I read last week is from Metafilter blog: "Scientists prove that lunch came before breakfast." In fact, journalists at major news sites all around the web reported that scientists have solved the infamous chicken-and-egg problem.
Which came first? The chicken. Definitively.

read more... Read more »

Freeman CL, Harding JH, Quigley D, & Rodger PM. (2010) Structural Control of Crystal Nuclei by an Eggshell Protein. Angewandte Chemie (International ed. in English), 49(30), 5135-5137. PMID: 20540126  

  • July 16, 2010
  • 07:39 PM

Acro-tastic! (with additional GADZOOKS!)

by Emma in we are all in the gutter

I’m in need of some cheering up today, as the fun observations I wanted to make with the Herschel Space Telescope have turned out to be impossible. Luckily, this observation planning also involved a lot of procrastination, which led me to this: the Dumb Or Overly Forced Astronomical Acronyms Site (DOOFAAS). On this site astronomer [...]... Read more »

John F. Beacom, & Mark R. Vagins. (2003) GADZOOKS! Antineutrino Spectroscopy with Large Water Cerenkov Detectors. Phys.Rev.Lett. 93 (2004) 171101. arXiv: hep-ph/0309300v1

  • July 16, 2010
  • 02:08 PM

Boost your Guitar Hero skills 101 - SLEEP! Really?

by Psychothalamus in Psychothalamus

We have been told that feeling well-rested while studying and reviewing your work just before bedtime enhances your memory for what you have studied. But when it comes to the role of sleep in motor memory, the answer is less clear. A recent research abstract presented at the 24th annual meeting of the Associated Professional Sleep Societies LLC by Dr Kevin Peters from Trent University suggests that sleep enhances our performance in complex motor learning tasks, as measured by an larger increase ........ Read more »

  • July 16, 2010
  • 02:02 PM

Perception of Supply Risk

by Daniel Dumke in SCRM Blog - Supply Chain Risk Management

One of the most published supply risk researchers is George A. Zsidisin. In his 2003 article he describes the characteristics of inbound supply that affect the perception of risk.

Supply Risk
The author defines supply risk as the potential occurrence of an incident associated with inbound supply from individual supplier failures or the supply market, in which its outcomes result in the inability of the purchasing firm to meet customer demand or cause threats to customer life and safety.
He........ Read more »

Zsidisin, G. (2003) Managerial Perceptions of Supply Risk. The Journal of Supply Chain Management, 39(1), 14-26. DOI: 10.1111/j.1745-493X.2003.tb00146.x  

  • July 16, 2010
  • 11:53 AM

Prehistoric mammal Prolibytherium had a “butterfly face”

by Laelaps in Laelaps

Exactly what Prolibytherium magnieri was, no one is quite sure. Since the time it was described in 1961, the 17-16.5 million year old mammal from Egypt and Libya has been closely allied with prehistoric relatives of deer (Palaeomerycidae), ancient giraffes (such as Sivatherium), and a motley group of giraffe cousins (Climacoceratidae). Many experts now agree [...]... Read more »

  • July 16, 2010
  • 11:53 AM

Phase synchronization

by Brandon Goodell in Bored Lunatic

Consider two pendula (penduli? pendulums?) that are on a bit of a wobbly table, oscillating back and forth.

Eventually, they synchronize. Once a huge mystery to physics, the fact that placing two pendulums on the same surface causes minute vibrations to transmit through that surface, causing the devices to become weakly coupled. The result is that, after a sufficiently long period of time swinging back and forth, the two pendulums become fully synchronous.

The Scholarpedia article, "Phase ........ Read more »

Izhikevich, E., & Ermentrout, B. (2008) Phase model. Scholarpedia, 3(10), 1487. DOI: 10.4249/scholarpedia.1487  

  • July 16, 2010
  • 11:27 AM

‘Molecular relay race’ at the heart of new targeted cancer therapy

by Cancer Research UK in Cancer Research UK - Science Update

A big problem in cancer treatment is how to deliver enough of the drugs needed to treat the tumour without causing excessive side effects. To make matters worse, cancers can develop resistance to drugs over time, meaning that increasingly higher doses and more potent cocktails of drugs are often needed to tackle the disease. But [...]... Read more »

Middleton, M., Knox, R., Cattell, E., Oppermann, U., Midgley, R., Ali, R., Auton, T., Agarwal, R., Anderson, D., Sarker, D.... (2010) Quinone Oxidoreductase-2-Mediated Prodrug Cancer Therapy. Science Translational Medicine, 2(40), 40-40. DOI: 10.1126/scitranslmed.3000615  

  • July 16, 2010
  • 11:24 AM

Evidence for role of microRNA in Melanoma

by Sally Church in Pharma Strategy Blog

Twitter is great for highlighting interesting journal articles, as I found when Edward Winstead from the NIH shared this paper from PLOSone on the importance of microRNA in melanoma in his Twitter stream (thanks, Ted!). There has been a lot...... Read more »

Haflidadóttir, B., Bergsteinsdóttir, K., Praetorius, C., & Steingrímsson, E. (2010) miR-148 Regulates Mitf in Melanoma Cells. PLoS ONE, 5(7). DOI: 10.1371/journal.pone.0011574  

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