Yeah, this is late. Sci’s STILL ILL (ARGH!!!) and also has a lot on her plate. But nothing holds back the blogging! I WILL GO ON. (My blog will go oooonnnnn…I swear I didn’t even LISTEN to that because the song sucks THAT MUCH. Bet I gave you an earworm, though!!) For today, I’d like [...]... Read more »
Bevilacqua L, Doly S, Kaprio J, Yuan Q, Tikkanen R, Paunio T, Zhou Z, Wedenoja J, Maroteaux L, Diaz S.... (2010) A population-specific HTR2B stop codon predisposes to severe impulsivity. Nature, 468(7327), 1061-6. PMID: 21179162
As a teacher, you have the opportunity to impact many lives—but less often is the focus on how students affect teachers. Challenging students take up more of their teachers’ time—and ... Read more »
Houts, R.M., Caspi, A., Pianta, R.C., Arseneault, L., & Moffitt, T.E. (2010) The challenging pupil in the classroom: the effect of the child on the teacher. Psychological science : a journal of the American Psychological Society / APS, 21(12), 1802-10. PMID: 21078897
In the early 1980s, psychologist Benjamin Libet conducted a relatively simple experiment that critically shaped the way we think about free-will. Participants sat facing a clock, keeping a finger on a button, and were instructed to lift the finger whenever they pleased, remembering the clock time corresponding to the time when they decided to move the finger. All the while, EEG was being recorded. Libet found that 300-500 msec before participants moved (and about 150 msec before reporting that t........ Read more »
Miller J, Shepherdson P, & Trevena J. (2010) Effects of Clock Monitoring on Electroencephalographic Activity: Is Unconscious Movement Initiation an Artifact of the Clock?. Psychological science : a journal of the American Psychological Society / APS. PMID: 21123855
If you happened to be a bacteria, you must prepare for trouble: shortage of food, temperature changes and so on. And when the trouble comes, you should respond accordingly. Stringent response system does exactly that: it integrates several input sources (aminoacid, fat and carbon limitation, temperature upshift to name a few) and alters concentration of the alarmone molecule ppGpp (GDP with 2 extra phosphates attached to the sugar moiety).ppGpp in turn regulates everything: transcription, transl........ Read more »
Sun D, Lee G, Lee JH, Kim HY, Rhee HW, Park SY, Kim KJ, Kim Y, Kim BY, Hong JI.... (2010) A metazoan ortholog of SpoT hydrolyzes ppGpp and functions in starvation responses. Nature structural , 17(10), 1188-94. PMID: 20818390
Mitkevich VA, Ermakov A, Kulikova AA, Tankov S, Shyp V, Soosaar A, Tenson T, Makarov AA, Ehrenberg M, & Hauryliuk V. (2010) Thermodynamic characterization of ppGpp binding to EF-G or IF2 and of initiator tRNA binding to free IF2 in the presence of GDP, GTP, or ppGpp. Journal of molecular biology, 402(5), 838-46. PMID: 20713063
Maciag M, Kochanowska M, Lyzeń R, Wegrzyn G, & Szalewska-Pałasz A. (2010) ppGpp inhibits the activity of Escherichia coli DnaG primase. Plasmid, 63(1), 61-7. PMID: 19945481
Gralla JD. (2005) Escherichia coli ribosomal RNA transcription: regulatory roles for ppGpp, NTPs, architectural proteins and a polymerase-binding protein. Molecular microbiology, 55(4), 973-7. PMID: 15686546
Buckstein MH, He J, & Rubin H. (2008) Characterization of nucleotide pools as a function of physiological state in Escherichia coli. Journal of bacteriology, 190(2), 718-26. PMID: 17965154
by Moselio Schaechter in Small Things Considered
Now that news of the arsenic-eating bacteria has saturated cyberspace, the airwaves, and even old-fashioned newsprint, we step back to raise a larger question: Why have so few elements from the periodic table made it into living things? You seldom hear about anything past the first few rows in the table. Turns out this is a gross oversight. Many more elements, previously unsuspected, are to be found in a large number of metalloproteins. So, move over, arsenic and make room for other elements.
U........ Read more »
Cvetkovic A, Menon AL, Thorgersen MP, Scott JW, Poole FL 2nd, Jenney FE Jr, Lancaster WA, Praissman JL, Shanmukh S, Vaccaro BJ.... (2010) Microbial metalloproteomes are largely uncharacterized. Nature, 466(7307), 779-82. PMID: 20639861
One of my favourite journals, Cancer Research, has a new paper available via open access (i.e. free to the public, thank you AACR), which you can obtain from the link in the Reference section below. # It caught my attention … Continue reading →... Read more »
di Tomaso, E., Snuderl, M., Kamoun, W., Duda, D., Auluck, P., Fazlollahi, L., Andronesi, O., Frosch, M., Wen, P., Plotkin, S.... (2011) Glioblastoma Recurrence after Cediranib Therapy in Patients: Lack of "Rebound" Revascularization as Mode of Escape. Cancer Research, 71(1), 19-28. DOI: 10.1158/0008-5472.CAN-10-2602
By: Dr. Ken Broda-Bahm - When Christine O'Donnell, the Tea Party favorite who won the Republican nomination for a Delaware Senate seat before losing in November's general election, received word of an U.S. Attorney's Office investigation and possible charges stemming from misuse of about $20,000 in campaign funds to pay her personal expenses, she immediately took to the airwaves. On a variety of network and cable news shows, she unequivocally denied the charges and went further to call the inves........ Read more »
Michele DeStefano Beardslee. (2009) Advocacy in the Court of Public Opinion, Installment One: Broadening the Role of Corporate Attorneys. The Georgetown Journal of Legal Ethics, 22(4). info:/
The immune system relies heavily on memory and recognition, with its success dependent on marshaling defenses against only the right infectious invaders. Scientists are finding that this memory requires a lot of moving parts, including molecules that grab pieces of bacteria and viruses, specialized cells that can determine whether those pieces are dangerous or not, [...]... Read more »
Scharf, L., Li, N., Hawk, A., Garzón, D., Zhang, T., Fox, L., Kazen, A., Shah, S., Haddadian, E., & Gumperz, J. (2010) The 2.5 Å Structure of CD1c in Complex with a Mycobacterial Lipid Reveals an Open Groove Ideally Suited for Diverse Antigen Presentation. Immunity, 33(6), 853-862. DOI: 10.1016/j.immuni.2010.11.026
Aviation and steering a company can be viewed as somehow alike. At least this is the starting point for the article by Srinivas (2009) reviewed today.
But unlike companies a pilot has some advantages: a clear starting point, a given destination, he knows on which path to get there, he knows anytime if he is off course and he also knows how to get back on track.
Company as a staggering Airplane
On the other hand within a company you have a hard time defining those parame........ Read more »
Srinivas, S. (2009) Effective Performance Management . Journal of Business Logistics, 30(2), 85-100. info:/
Some weeks back I chided Jonah Lehrer for his assertion that he'd
love [e-readers] to include a feature that allows us to undo their ease, to make the act of reading just a little bit more difficult. Perhaps we need to alter the fonts, or reduce the contrast, or invert the monochrome color scheme. Our eyes will need to struggle, and we’ll certainly read slower, but that’s the point: Only then will we process the text a little less unconsciously, with less reliance on the ventral pathway. We ........ Read more »
Connor Diemand-Yauman, Daniel M. Oppenheimer, & Erikka B. Vaughan. (2011) Fortune favors the bold (and the italicized): Effects of disfluency on educational outcomes. Cognition, 111-115. info:/doi:10.1016/j.cognition.2010.09.012
There’s a famous story about a very long, skinny flower.
In Madagascar, there is an orchid in which the nectar is about 30 centimeters away from the opening of the flower. When examples of these flowers arrived at Charles Darwin’s doorstep in 1862, he knew that most orchids in this group were pollinated by moths. But there was no known moth that was big enough to do so.
Later that year, in a book on flower pollination, Darwin wrote, “in Madagascar there must be moths with proboscises cap........ Read more »
Bauder J, Lieskonig N, & Krenn H. (2010) The extremely long-tongued Neotropical butterfly Eurybia lycisca (Riodinidae): Proboscis morphology and flower handling. Arthropod Structure . DOI: 10.1016/j.asd.2010.11.002
Kritsky G. (1991) Darwin's Madagascan Hawk Moth Prediction. American Entomologist, 37(4), 206-210. info:/
Nanotechnology researchers working on self-powered nanodevices - nanoscale systems that scavenge energy from their surrounding environment - have been experimenting with various power sources ranging from piezoelectric systems to sound. However, the most abundant energy available in biosystems is chemical and biochemical energy, such as glucose. Researchers in China have now reported an nanowire-based biofuel cell based on a single proton conductive polymer nanowire for converting chemical energ........ Read more »
Pan, C., Wu, H., Wang, C., Wang, B., Zhang, L., Cheng, Z., Hu, P., Pan, W., Zhou, Z., Yang, X.... (2008) Nanowire-Based High-Performance “Micro Fuel Cells”: One Nanowire, One Fuel Cell. Advanced Materials, 20(9), 1644-1648. DOI: 10.1002/adma.200700515
by Rita Handrich in The Jury Room
The new book, Typography for Lawyers, has been getting a lot of attention for encouraging more attractive font in legal communications. The book is getting rave reviews from attorneys who realize that part of persuasion is visual presentation. And we think Matthew Butterick (the author) is onto something. Perhaps he’s been reading social sciences research along [...]
Related posts:Secret Weapon: The Chairs in the Jury Box?
But they did it on purpose!
You’re not too old for a story (but yo........ Read more »
In an effort to extend the data set for influenza pandemic planning, Valleron, Cori, Meurisse, Carrat, and Boëlle gathered data from 15 countries in the northern hemisphere that experienced the ‘Russian flu’ pandemic in the winter of 1889-1890. The pandemic was first recorded in St. Petersburg, Russia. Within a mere four months it had spread [...]... Read more »
Valleron AJ, Cori A, Valtat S, Meurisse S, Carrat F, & Boëlle PY. (2010) Transmissibility and geographic spread of the 1889 influenza pandemic. Proceedings of the National Academy of Sciences of the United States of America, 107(19), 8778-81. PMID: 20421481
Cancer is a loaded word for many biologists—it is made up of thousands of different diseases when you realize how many different paths can be taken in order for cells to lead to cancer. There are so many biologists investigating cancer, and sometimes there are discoveries that shake up our understanding. These shake-ups are key to making the big steps towards a cure that patients, survivors, and victims all hope for.... Read more »
Wang, R., Chadalavada, K., Wilshire, J., Kowalik, U., Hovinga, K., Geber, A., Fligelman, B., Leversha, M., Brennan, C., & Tabar, V. (2010) Glioblastoma stem-like cells give rise to tumour endothelium. Nature, 468(7325), 829-833. DOI: 10.1038/nature09624
Ricci-Vitiani, L., Pallini, R., Biffoni, M., Todaro, M., Invernici, G., Cenci, T., Maira, G., Parati, E., Stassi, G., Larocca, L.... (2010) Tumour vascularization via endothelial differentiation of glioblastoma stem-like cells. Nature, 468(7325), 824-828. DOI: 10.1038/nature09557
If you’re thinking of getting a flu shot, you may want to consider the impact of your pain medication on its effectivity. Professor Richard P. Phipps from the University of Rochester states, “research shows that pain relievers interfere with the effect of the vaccine.”
Many of the pain medicines examined by Dr. Phillips are anti-inflammatory, for [...]... Read more »
Bancos S, Bernard MP, Topham DJ, & Phipps RP. (2009) Ibuprofen and other widely used non-steroidal anti-inflammatory drugs inhibit antibody production in human cells. Cellular immunology, 258(1), 18-28. PMID: 19345936
A cocktail of three common B vitamins slowed the rate of brain shrinkage over two years in elderly patients with mild cognitive impairment, according to researchers at the University of Oxford.
As a hospitalist, I see 10 or 20 brain scans every week. A healthy 40-year-old brain nicely fills out the allotted space in the skull. [...]... Read more »
Smith, A., Smith, S., de Jager, C., Whitbread, P., Johnston, C., Agacinski, G., Oulhaj, A., Bradley, K., Jacoby, R., & Refsum, H. (2010) Homocysteine-Lowering by B Vitamins Slows the Rate of Accelerated Brain Atrophy in Mild Cognitive Impairment: A Randomized Controlled Trial. PLoS ONE, 5(9). DOI: 10.1371/journal.pone.0012244
Learned something new about field dependence and field independence. These are individual differences in learning style. There is a difference in how people perceive discrete items within a surrounding field. People at the one end of the extreme where perception was strongly dominated by the prevailing field were designated “field-dependent.” Field-dependent learners see the [...]
Related posts:Forest plots: trying to see the wood and the trees
Individual Differences in Empathy
P........ Read more »
Glicksohn, J., & Rechtman, S. (2010) Profiling the profilers: Who is watching our backs?. Personality and Individual Differences. DOI: 10.1016/j.paid.2010.12.010
And now for something completely different (or depending on your history folder, something exceedingly familiar)...I'm going to begin this post with a copy of an Abstract from a paper entitled 'The pleasure is momentary…the expense damnable? The inﬂuence of pornography on rape and sexual assault' (Ferguson & Hartley, 2009) in Aggression and Violent behaviour.The effects of p; (read more)
Source: Rift - Discipline: Psychology... Read more »
Markey, P., & Markey, C. (2010) Changes in pornography-seeking behaviors following political elections: an examination of the challenge hypothesis. Evolution and Human Behavior, 31(6), 442-446. DOI: 10.1016/j.evolhumbehav.2010.06.004
Ferguson, C., & Hartley, R. (2009) The pleasure is momentary…the expense damnable?The influence of pornography on rape and sexual assault. Aggression and Violent Behavior, 14(5), 323-329. DOI: 10.1016/j.avb.2009.04.008
Wallen, K., & Rupp, H. (2010) Women's interest in visual sexual stimuli varies with menstrual cycle phase at first exposure and predicts later interest. Hormones and Behavior, 57(2), 263-268. DOI: 10.1016/j.yhbeh.2009.12.005
Everyone knows there's a big gap in worldwide between the have and the have nots in one area: internet access. A new study looked at that gap where you would expect to see it in an obvious way. They looked at computer and internet use in homeless populations in the Philadelphia area. The results are somewhat surprising. Right now 58% of households have some kind of computer and 76% of these households have access to the internet. Of the homeless population they reported an average homeless ........ Read more »
Eyrich-Garg, K. (2011) Sheltered in cyberspace? Computer use among the unsheltered ‘street’ homeless. Computers in Human Behavior, 27(1), 296-303. DOI: 10.1016/j.chb.2010.08.007
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