Post List

  • January 17, 2010
  • 01:08 PM

CAPRI: Selected Talks II

by Nir London in Macromolecular Modeling Blog

This is the third post in the CAPRI series, summarizing the presentations of Jeffrey Gray, Zhiping Weng, and Miriam Eisenstein, as provided by the speakers. More to appear in the continuation of the series.

... Read more »

Hwang H, Pierce B, Mintseris J, Janin J, & Weng Z. (2008) Protein-protein docking benchmark version 3.0. Proteins, 73(3), 705-9. PMID: 18491384  

Heifetz, A. (2002) Electrostatics in protein-protein docking. Protein Science, 11(3), 571-587. DOI: 10.1110/ps.26002  

Berchanski, A., Shapira, B., & Eisenstein, M. (2004) Hydrophobic complementarity in protein-protein docking. Proteins: Structure, Function, and Bioinformatics, 56(1), 130-142. DOI: 10.1002/prot.20145  

  • January 17, 2010
  • 12:45 PM

A Possible Physical Mechanism of Cancer Metastasis

by Michael Long in Phased

Ralf Kemkemer (Max Planck Institute for Metals Research, Germany) and coworkers have shown that a bioactive lipid can enable pancreatic cancer cells to dramatically alter their shape, possibly enabling them to penetrate organs and spread throughout the body. This news feature was written on January 17, 2010.... Read more »

  • January 17, 2010
  • 10:38 AM

Influential Statisticians

by Michael Bishop in Permutations

Comments on Wright's interesting article.... Read more »

  • January 16, 2010
  • 10:30 PM

Importing Food

by teofilo in Gambler's House

One of the most interesting and potentially productive lines of research in Southwestern archaeology these days involves the use of chemical analyses of various archaeological materials to extract more information about the societies that used them than is apparent just from looking at them.  The oldest and most established type of research like this is [...]... Read more »

  • January 16, 2010
  • 07:24 PM

Sexual Orientation, Sociosexuality, and Sexual Dimorphism

by Wayne Hooke in The Psychology of Beauty

Using digitally manipulated levels of sexual dimorphism in human male and female faces (like the ones to the right), Glassenberg (2009) found that, compared to heterosexual women, homosexual women preferred greater masculinization in female faces [Brown-Forsythe t(303.38) = -2.92, p<.01] while heterosexual women preferred greater masculinization in male faces [t(375) = 6.77, p<.001]. Compared [...]... Read more »

  • January 16, 2010
  • 06:49 PM

Keep calm and carry on: as long as your orexin levels are low

by geekheartsscience in geek!

Scientists link the orexin system in the brain to panic disorder, paving the way for research into new treatments for severe anxiety disorder.
Panic disorder is a severe anxiety disorder characterised by recurring panic attacks. Sufferers are suddenly overcome with a feeling of terror and often have physical symptoms such as increased breathing and heart rates. [...]... Read more »

Johnson, P., Truitt, W., Fitz, S., Minick, P., Dietrich, A., Sanghani, S., Träskman-Bendz, L., Goddard, A., Brundin, L., & Shekhar, A. (2009) A key role for orexin in panic anxiety. Nature Medicine, 16(1), 111-115. DOI: 10.1038/nm.2075  

  • January 16, 2010
  • 06:23 PM

The Moon, where the Helium-3 from the Sun is

by The Astronomist in The Astronomist.

Moon is a 2009 science fiction film about astronaut Sam Bell who is the solitary worker on the moon. Sam is at the end of a three-year stint on the Moon so the film begins as if it was the denouement of another quieter story. When an accident occurs Sam suddenly meets himself for the first time.I am adapt at finding flaws in science fiction films, but Moon nails a lot of science as well as could be expected. The most incredulous point about the film for me was the lack of a radio array on the fa........ Read more »

  • January 16, 2010
  • 11:45 AM

First steps in direct exoplanet spectroscopy

by sarah in One Small Step

Astronomers collaborating from both sides of the Atlantic have obtained the first direct spectrum of an exoplanet. The news here is mainly that they managed to record the spectrum and separate it reliably from that of the host star. Their short letter in ApJ, posted to astro-ph yesterday, doesn’t delve deeply into the implications of [...]... Read more »

M. Janson, C. Bergfors, M. Goto, W. Brandner, & D. Lafreniere. (2010) Spatially resolved spectroscopy of the exoplanet HR 8799 c. accepted by A. arXiv: 1001.2017v1

  • January 16, 2010
  • 03:15 AM

The Moon, Where helium-3 from the sun is

by Alexander in The Astronomist.

Moon is a 2009 science fiction film about astronaut Sam Bell who is a solitary miner on the moon. When Helium and fusion was mentioned at the beginning of the film I was delighted that they had based the story on a kernel of science. The energy source they are gathering from the moon is Helium-3. Helium-3 is a light isotope of helium with two protons and one neutron which is suitable as a fusion fuel. I have done some research into the literature to determine just how feasible this 3He min........ Read more »

  • January 15, 2010
  • 07:07 PM

CoQ10 (coenzyme q10)- is it worth it - from an athletic perspective

by mc in begin to dig (b2d)

ResearchBlogging.orgIn the world of alluring supplements, coq10 feels like a relative new comer. Is it worth considering adding to one's regimen? CoQ10 is being investigated in so many contexts, the following is a consideration of where it's been looked at in athletics to help make a determination as to whether or not it's worth considering for your own regimen. Shaking the magic 8 ball, signs point to Yes.... Read more »

Gökbel, Hakk; Gül, Ibrahim; Belviranl, Muaz; Okudan, Nilsel. (2101) The Effects Of Coenzyme Q10 Supplementation on Performance During Repeated Bouts of Supramaximal Exercise in Sedentary Men. Journal of Strength and Conditioning Research, 24(1), 97-102. info:/10.1519/JSC.0b013e3181a61a50

  • January 15, 2010
  • 06:58 PM

Data sharing in Ecology and Evolution

by Kevin Emerson in skeetersays

Any scientist interested in analysis of genetic data knows the value of online repositories for sequence data (such as genBank). Any researcher publishing analyses of sequence data likely is required by publishers to make their sequence data publicly available in such a database. Not only does this allow for other researchers to validate one's work, it also allows for more general research that may use those sequences. In fact there is a growing number of research programs that revolve solely........ Read more »

Whitlock, M., McPeek, M., Rausher, M., Rieseberg, L., & Moore, A. (2010) Data Archiving. The American Naturalist, 175(2), 145-146. DOI: 10.1086/650340  

  • January 15, 2010
  • 04:59 PM

Doing It For the Kids: The Evolution of Migration

by GrrlScientist in Living the Scientific Life (Scientist, Interrupted)

tags: evolutionary biology, behavioral ecology, life history, migration, long-distance migration,birds,ornithology,,peer-reviewed research, peer-reviewed paper

White-rumped sandpiper, Calidris fuscicollis, chicks on Bylot Island, Nunavut, Canada.

Image: Laura McKinnon [larger view]

I recently told you about research that used new microtechnology to document the incredible journey of Arctic Terns, a small bird species that annually migrates from its wintering area in Anta........ Read more »

McKinnon, L., Smith, P., Nol, E., Martin, J., Doyle, F., Abraham, K., Gilchrist, H., Morrison, R., & Bety, J. (2010) Lower Predation Risk for Migratory Birds at High Latitudes. Science, 327(5963), 326-327. DOI: 10.1126/science.1183010  

  • January 15, 2010
  • 04:58 PM

A Leaky Premise

by Journal Watch Online in Journal Watch Online

Rationale for hunting Antarctic minke whales doesn’t hold water

... Read more »

Ruegg, K., Anderson, E., Baker, C., Vant, M., Jackson, J., & Palumbi, S. (2010) Are Antarctic minke whales unusually abundant because of 20th century whaling?. Molecular Ecology, 19(2), 281-291. DOI: 10.1111/j.1365-294X.2009.04447.x  

  • January 15, 2010
  • 04:44 PM

Is it a substance use disorder or is he a substance abuser?

by DrugMonkey in DrugMonkey

This is awesome. I've been waiting for the paper to show up ever since I saw the poster presentation at a meeting last year. Or maybe I just saw a related type of poster because I seem to recall the analysis being particularly critical of general medical doctors? At any rate, this is a pretty important finding because it speaks to the stigma that surrounds certain types of medical problems. This stigma might have serious implications for judicial decision making when crimes are involved, persona........ Read more »

  • January 15, 2010
  • 04:30 PM

Silencing brain cells – a step towards, or away from, curing chronic pain?

by Lorimer Moseley in BodyInMind

Here is a very cool experiment from Ed Boyden’s lab at MIT: they have used a fungus (yes, you read that right – a fungus) to turn off neurons using a proton pump that is turned on by blue-green light.  Sure, the neurons were in a culture. Sure, they weren’t human neurons. But this is [...]... Read more »

Lorimer Moseley. (2010) Silencing brain cells - a step towards, or away from, curing chronic pain?. BodyinMind. info:/

  • January 15, 2010
  • 02:16 PM

Prehistoric ballistics, or Mythbusters meets archaeology

by Julien Riel-Salvatore in A Very Remote Period Indeed

Nicole Waguespack and a bunch of others (including four of the Mythbusters gang, which leads one to wonder whether this will be the basis of a future episode) ask the question: "Given that so many hunter-gatherers use/d stone-tipped projectile, what are the advantages of a stone tip relative to one whose point is simply sharpened wood?" This is a good question to ask, since crafting an projectile point from stone consumes more time, effort and resources than simply sharpening the end of the shaf........ Read more »

Waguespack, N.M., Surovell, T.A., Denoyer, A., Dallow, A., Savage, A., Hyneman, J., & Tapster, D. (2009) Making a point: wood- versus stone-tipped projectiles. Antiquity, 786-800. info:/

  • January 15, 2010
  • 12:19 PM

#AACR Personalized therapy in lung cancer - part 2

by Sally Church in Pharma Strategy Blog

As part of a four part series on personalized therapy for lung cancer, here is the second summary in the series based on some fascinating lectures at the AACR meeting on the molecular origins in lung cancer this week. The...... Read more »

  • January 15, 2010
  • 10:16 AM

Capture and Subassembly with Jay Shendure

by Daniel Koboldt in Massgenomics

Yesterday our 2010 Genetics Seminar Series kicked off with Jay Shendure (Univ. Washington) whose twelve-exome paper landed in Nature late last year. His talk covered three very different applications of next-generation sequencing: high-throughput mutational studies of core promoters, sub-assembly of Illumina reads to 454-length contigs, and exome capture to unravel Mendelian disorders.
Mutational Profiling
First, Dr. Shendure [...]... Read more »

Ng SB, Turner EH, Robertson PD, Flygare SD, Bigham AW, Lee C, Shaffer T, Wong M, Bhattacharjee A, Eichler EE.... (2009) Targeted capture and massively parallel sequencing of 12 human exomes. Nature, 461(7261), 272-6. PMID: 19684571  

  • January 15, 2010
  • 09:48 AM

Deconstructing Social Darwinism, Part IV

by Eric Michael Johnson in The Primate Diaries

Part 1 / Part 2 / Part 3 / Part 4

Richard Hofstadter wrote in Social Darwinism in American Thought that this political theory was "one of the leading strains in American conservative thought for more than a generation." In this series I have shown many of the inconsistencies that exist in the literature on social Darwinism and have emphasized the main objections that scholars have raised about the utility of the term.

In Part 1 I presented the standard definition of social Darwinism as defi........ Read more »

  • January 15, 2010
  • 09:29 AM

I’ll see your bornaviruses, and raise with a poxvirus

by iayork in Mystery Rays from Outer Space

There’s been recent excitement over the discovery of bornaviruses fixed in the human genome1, 2.  Exciting and unexpected as that is, as usual, the insects are way ahead of us.  The genome of a parasitoid wasp has poxvirus sequences in it!

Detecting ancient lateral transfers is more problematic. By examining protein domain arrangements in Nasonia relative [...]... Read more »

, ., Werren, J., Richards, S., Desjardins, C., Niehuis, O., Gadau, J., Colbourne, J., Beukeboom, L., Desplan, C., Elsik, C.... (2010) Functional and Evolutionary Insights from the Genomes of Three Parasitoid Nasonia Species. Science, 327(5963), 343-348. DOI: 10.1126/science.1178028  

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