Post List

  • October 26, 2009
  • 12:31 PM
  • 809 views

Autism, Schizophrenia and CNV in 16p11.2

by sandygautam in The Mouse Trap





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There is a letter published in the advance online edition of Nature Genetics, that reports that microduplication of genes in the region 16p11.2 are associated with the risk of schizophrenia in a large cohort. It has been earlier shown that microdeletions in the same region confer the risk of Autism.Thus, it seems [...]Rating: 0.0/10 (0 votes cast)


Related posts:CNVs and Autism/ Schizophrenia I had been meaning to comment on a recent paper...Autism and Schizophrenia........ Read more »

McCarthy, S., Makarov, V., Kirov, G., Addington, A., McClellan, J., Yoon, S., Perkins, D., Dickel, D., Kusenda, M., Krastoshevsky, O.... (2009) Microduplications of 16p11.2 are associated with schizophrenia. Nature Genetics. DOI: 10.1038/ng.474  

  • October 26, 2009
  • 12:05 PM
  • 1,000 views

How to synchronize flowering without really trying

by Jeremy Yoder in Denim and Tweed

One way plants can gain an advantage in their dealings with pollinators, seed dispersers, or herbivores is to act collectively. For instance, when oak trees husband their resources for an extra-big crop of acorns every few years instead of spreading them out, acorn-eating rodents are overwhelmed by the bumper crop, and more likely to miss some, or even forget some of the nuts they cache. These benefits of synchronized mass seed production, or "masting," are straightforward, but how it happens is........ Read more »

  • October 26, 2009
  • 12:00 PM
  • 895 views

What’s wrong with copyright?

by David Bradley in Sciencetext

Without copyright protection creative types would not create. That, apparently, is one of the defenses put forward by the likes of the RIAA and the MPAA. These organizations chase after file sharers and attempt to gain millions of dollars of recompense each year from people who swap music and movie torrents. But isn’t this defense [...]Post from: David Bradley's Sciencetext Tech TalkWhat’s wrong with copyright?
... Read more »

Denis Borges Barbosa. (2010) On artefacts and middlemen: a musician’s note on the economics of copyright. International Journal of Intellectual Property Management, 4(1/2), 23-44. info:/

  • October 26, 2009
  • 12:00 PM
  • 554 views

Understanding Our Bodies: The Role of Antioxidants

by Christie Wilcox in Observations of a Nerd

Are antioxidants good for you? The short answer is yes, but buyer beware. Just because something is good for you doesn’t mean you should start taking a giant mega-dose of it. Antioxidants are great when the come from natural sources as a part of a healthy diet. But like everything else, a closer look at their physiological action explains why you can get too much of a good thing.... Read more »

Stadtman, E. (1992) Protein oxidation and aging. Science, 257(5074), 1220-1224. DOI: 10.1126/science.1355616  

Loh, K., Deng, H., Fukushima, A., Cai, X., Boivin, B., Galic, S., Bruce, C., Shields, B., Skiba, B., & Ooms, L. (2009) Reactive Oxygen Species Enhance Insulin Sensitivity. Cell Metabolism, 10(4), 260-272. DOI: 10.1016/j.cmet.2009.08.009  

Valko M, Leibfritz D, Moncol J, Cronin MT, Mazur M, & Telser J. (2007) Free radicals and antioxidants in normal physiological functions and human disease. The international journal of biochemistry , 39(1), 44-84. PMID: 16978905  

Miller ER 3rd, Pastor-Barriuso R, Dalal D, Riemersma RA, Appel LJ, & Guallar E. (2005) Meta-analysis: high-dosage vitamin E supplementation may increase all-cause mortality. Annals of internal medicine, 142(1), 37-46. PMID: 15537682  

  • October 26, 2009
  • 12:00 PM
  • 552 views

Understanding Our Bodies: The Role of Antioxidants

by Christie Wilcox in Nutrition Wonderland

Are antioxidants good for you? The short answer is yes, but buyer beware. Just because something is good for you doesn’t mean you should start taking a giant mega-dose of it. Antioxidants are great when the come from natural sources as a part of a healthy diet. But like everything else, a closer look at their physiological action explains why you can get too much of a good thing.... Read more »

Stadtman, E. (1992) Protein oxidation and aging. Science, 257(5074), 1220-1224. DOI: 10.1126/science.1355616  

Loh, K., Deng, H., Fukushima, A., Cai, X., Boivin, B., Galic, S., Bruce, C., Shields, B., Skiba, B., & Ooms, L. (2009) Reactive Oxygen Species Enhance Insulin Sensitivity. Cell Metabolism, 10(4), 260-272. DOI: 10.1016/j.cmet.2009.08.009  

Valko M, Leibfritz D, Moncol J, Cronin MT, Mazur M, & Telser J. (2007) Free radicals and antioxidants in normal physiological functions and human disease. The international journal of biochemistry , 39(1), 44-84. PMID: 16978905  

Miller ER 3rd, Pastor-Barriuso R, Dalal D, Riemersma RA, Appel LJ, & Guallar E. (2005) Meta-analysis: high-dosage vitamin E supplementation may increase all-cause mortality. Annals of internal medicine, 142(1), 37-46. PMID: 15537682  

  • October 26, 2009
  • 08:00 AM
  • 1,057 views

The princess and the perfume, a hermit crab fairy tale

by Zen Faulkes in NeuroDojo

Once upon a time, there lived a princess in a far away land. The princess was young and fair, and this drew the attention of a knight. Though the knight was strong, the princess loved him not.Enraged, the knight captured the princess and held her in his castle, and told her cruelly that they would soon be wed.The princess was not strong enough to escape the knight, though she tried many times. Still the knight kept her, guarded in his castle.But though the princess was not powerful strong, she w........ Read more »

  • October 26, 2009
  • 06:55 AM
  • 789 views

The upside of depression

by Andrew Lyons in The Psych Student

A look at the research findings of Paul Andrew and Anderson Thomson, Jr. into the evolutionary uses of depression and current treatments which see it as a disorder.

I’m interested in this as it points to something I think needs addressing in our culture, where constant happiness is often seen as the gold standard of wellbeing.... Read more »

  • October 26, 2009
  • 06:37 AM
  • 931 views

Unusual Changes in Sexuality: Case Studies in Neurology

by The Neurocritic in The Neurocritic

Fig. 1 (Currier et al., 1971). Scalp EEG showing sharp wave activity from left anterior temporal region.In the last post we learned a bit about hypergraphia, a compulsion to write that sometimes occurs in those with temporal lobe epilepsy (TLE). According to the late behavioral neurologist Norman Geschwind (reprinted in 2009; also see Devinsky & Schachter, 2009), hypergraphia is one in a cluster of interictal [between seizure] personality traits in some TLE patients1 which can also include ........ Read more »

  • October 26, 2009
  • 05:00 AM
  • 912 views

Powerline corridors as breeding habitat for birds...

by Rob Goldstein in Conservation Maven

... Read more »

  • October 26, 2009
  • 04:48 AM
  • 1,928 views

Sunday Protist - Nucleariids

by Psi Wavefunction in Skeptic Wonder

While exploring the various corners of the protistan world, I've been neglecting our close relatives - the Opisthokonts. Let's quickly remedy the situation.A couple weekends ago I had some pond water on hand, and it turned out to be quite productive. I was on a bit of a heliozoan and amoeba spree when I encountered these things:At first it seemed like a 'heliozoan'*, but wasn't quite round enough. Then I noticed filopodia. Heliozoa with filopodia? Nah. But it didn't quite qualify for your typica........ Read more »

  • October 26, 2009
  • 04:46 AM
  • 984 views

Young children's moral understanding more sophisticated than previously thought

by Christian Jarrett in BPS Research Digest

When her Daily Mail column about Stephen Gately's death provoked an avalanche of complaints, the disgraced Jan Moir issued a press statement in which she said "it was never [her] intention" to upset people. Defensively speaking, Moir's choice of words was astute. In judging moral responsibility, we adults focus almost exclusively on intention rather than outcome. Stated starkly, the person who deliberately attempts to kill an innocent, but fails, is judged as more evil than the person who accide........ Read more »

Nobes G, Panagiotaki G, & Pawson C. (2009) The influence of negligence, intention, and outcome on children's moral judgments. Journal of experimental child psychology, 104(4), 382-97. PMID: 19740483  

  • October 26, 2009
  • 02:22 AM
  • 1,069 views

A surprisingly compact early galaxy

by Charles Daney in Science and Reason

Astronomers are beginning to learn significant details of the structure of galaxies in the early universe. And what they're learning is rather surprising: at least some early galaxies are almost as massive as otherwise similar galaxies in the present universe, yet they are much smaller in linear size, by a factor of five, thus much more compact.What time period are we talking about here? It's not actually the time that the earliest galaxies formed, which was less than a billion years after the b........ Read more »

  • October 26, 2009
  • 01:48 AM
  • 292 views

Nautilus Night - Cephalopod of Diamonds

by Eric Heupel in The Other 95%

Ok. I said for each of the Ocean in the Classroom projects fully funded I would put up a post about one invert from the deck of cards I have been working on, along with a sneak peak at a card. So, since the Making Waves, Oceans and Landforms got fully funded, and in honor of Nautilus Night I bring you the Cephalopod of Diamonds - The Chambered Nautilus.Classification for the Chambered NautilusKingdomAnimaliaPhylumMolluscaClassCephalopodaOrderNautilidaFamilyNautilidaeGenusNautilusSpeciesN. belaue........ Read more »

  • October 26, 2009
  • 01:15 AM
  • 627 views

Grasping The (extracellular) Matrix, Location, location, location! and more in my picks of the week from RB

by Alejandro Montenegro-Montero in MolBio Research Highlights

Another week has gone by and some very interesting molbio blog posts have been aggregated to Researchblogging.org. Every week [see my opening post on the matter], I'll select some blog posts I consider particularly interesting in the field of molecular biology [see here to get a sense of the criteria that will be used], briefly describe them and list them here for you to check out.Note that I'm ... Read more »

Anthis NJ, Wegener KL, Ye F, Kim C, Goult BT, Lowe ED, Vakonakis I, Bate N, Critchley DR, Ginsberg MH.... (2009) The structure of an integrin/talin complex reveals the basis of inside-out signal transduction. The EMBO journal. PMID: 19798053  

Guelen, L., Pagie, L., Brasset, E., Meuleman, W., Faza, M., Talhout, W., Eussen, B., de Klein, A., Wessels, L., de Laat, W.... (2008) Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions. Nature, 453(7197), 948-951. DOI: 10.1038/nature06947  

  • October 25, 2009
  • 07:01 PM
  • 1,008 views

A conceptual model of Supply Chain Flexibility

by Jan Husdal in husdal.com

What do you do when you find two research papers by the same three authors, published the same year, in two different journals, with almost the same title?  A conceptual model of supply chain flexibility and Supply Chain Flexibility: Building a New Model by Rhonda R Lummus, Leslie K Duclos and Robert J Vokurka [ ... ]... Read more »

Duclos, L., Vokurka, R., & Lummus, R. (2003) A conceptual model of supply chain flexibility. Industrial Management , 103(6), 446-456. DOI: 10.1108/02635570310480015  

Lummus, Rhonda R., Duclos, Leslie K., & Vokurka, Robert J. (2003) Supply Chain Flexibility: Building a New Model. Global Journal of Flexible Systems Management, 4(4), 1-13. info:other/

  • October 25, 2009
  • 04:59 PM
  • 1,377 views

Hypnosis for chronic pain management: How it works maybe?

by Bronwyn Thompson in Healthskills: Skills for Healthy Living


There are plenty of people who look at me as if I’m stepping right into woowoo when I start to talk about hypnosis for managing chronic pain. I’m happy to say that science has provided some good evidence that not only does hypnosis have a neurophysiological basis, but it also has some good effect.
What [...]... Read more »

  • October 25, 2009
  • 04:58 PM
  • 1,127 views

The doctors who hasten death

by Tom Rees in Epiphenom



... Read more »

  • October 25, 2009
  • 01:56 PM
  • 828 views

NextGen sequencing: What Is It Good For?

by Lab Rat in Lab Rat

Sequencing DNA has become a major industry. The genetic code of an organism contains huge amounts of data, and the potential for a greater understanding of how it works at an intracellular level, and whole centers and genome sequencing factories now exist to fill this need. While most of the sequencing is still done using a modified and more efficient version of Sanger's original dideoxy method, next-generation sequencing machines are starting to emerge that can achieve what is imaginatively nam........ Read more »

  • October 25, 2009
  • 01:08 PM
  • 593 views

Crepidula Fornicata

by Eric Heupel in The Other 95%

We've got two new Ocean Inspired Donors Choose projects that have been funded in the Oceans in the Classroom Challenge! The first one that was funded on Thursday was the awesome Invertebrates in my Tank project that will provide lots of kids with the opportunity to explore one of our favorite subjects: marine inverts! The Inverts in my Tank card is the 6 of Spades — The Slipper Snail, Crepidula fornicata.Classification for the Atlantic Slippersnail KingdomAnimalia PhylumMollusca ClassBivalv........ Read more »

  • October 25, 2009
  • 12:01 PM
  • 1,138 views

Do We Need a Cochrane Review to Tell Us That Women Should Move in Labor?

by Amy Romano in Science & Sensibility

I am reposting this post from the archives in anticipation of this week’s Healthy Birth Blog Carnival about movement in labor. It was one of the first posts I ever wrote, back before anyone was reading this blog. It’s also one of my personal favorites.
Earlier this year, media outlets shared the news of a new [...]... Read more »

Lawrence A, Lewis L, Hofmeyr GJ, Dowswell T, & Styles C. (2009) Maternal positions and mobility during first stage labour. Cochrane database of systematic reviews (Online). PMID: 19370591  

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