Diabetes is the leading cause of nontraumatic amputation in developed nations. Lower-limb amputations are particularly common in type 2 diabetes and impose a substantial burden on the patient’s and caregiver’s quality of life, as well as profound economic and health care burdens for the individual and society. Many studies have attempted to outline the risk [...]... Read more »
Tseng, C. (2006) Prevalence of lower-extremity amputation among patients with diabetes mellitus: Is height a factor?. Canadian Medical Association Journal, 174(3), 319-323. DOI: 10.1503/cmaj.050680
Rajamani, K., Colman, P., Li, L., Best, J., Voysey, M., D'Emden, M., Laakso, M., Baker, J., & Keech, A. (2009) Effect of fenofibrate on amputation events in people with type 2 diabetes mellitus (FIELD study): a prespecified analysis of a randomised controlled trial. The Lancet, 373(9677), 1780-1788. DOI: 10.1016/S0140-6736(09)60698-X
GPS plays an important role in wildlife conservation by enabling managers to track the movements of animals. But sometimes wildlife biologists want to know more than just where an animal is located at any given time - sometimes they also want to know what an animal is actually doing...... Read more »
Löttker, P., Rummel, A., Traube, M., Stache, A., Šustr, P., Müller, J., & Heurich, M. (2009) New Possibilities of Observing Animal Behaviour from a Distance Using Activity Sensors in Gps-Collars: An Attempt to Calibrate Remotely Collected Activity Data with Direct Behavioural Observations in Red Deer . Wildlife Biology, 15(4), 425-434. DOI: 10.2981/08-014
My latest acquaintance in supply chain risk research methodology is developing drivers and dependants using interpretive structural modelling (ISM). This is good example of how it can be applied.... Read more »
Faisal, M., Banwet, D., & Shankar, R. (2006) Supply chain risk mitigation: modeling the enablers. Business Process Management Journal, 12(4), 535-552. DOI: 10.1108/14637150610678113
There's little doubt that many conceptions of attractiveness are faddish - the size zero female model being an obvious example. However, other notions of beauty are more hard-wired, perhaps reflecting an evolutionary adaptation. These aspects of appearance have come to be associated with fertility, signifying 'reproductive fitness' to potential mates. Male facial symmetry is one example. Another is the hour-glass female form. Men in cultures across world report a preference for women with a lowe........ Read more »
Platek, S., & Singh, D. (2010) Optimal Waist-to-Hip Ratios in Women Activate Neural Reward Centers in Men. PLoS ONE, 5(2). DOI: 10.1371/journal.pone.0009042
Headache, by Robert Magginetti (Tranquility Base)In the last post we learned about Alice in Wonderland syndrome, a rare phenomenon involving distortions of visual perception and body image, most often caused by migraines. Although a specialty practice in headache might seem dull [so to speak] at first glance to those interested in behavioral neurology, unusual and colorfully-named types of headaches can make things more interesting. In Case Studies of Uncommon Headaches (2006), Dr. Randolph Evan........ Read more »
I rarely think about how invasive species affect genetics. It’s always in terms of ecosystems or species: invasive brown tree snakes gobbling up birds and lizards in Guam, or zebra mussels overwhelming and altering the environment of the Great Lakes. How one species outcompetes and replaces another, changing the natural system. This is partly [...]... Read more »
Fitzpatrick, B., Johnson, J., Kump, D., Smith, J., Voss, S., & Shaffer, H. (2010) Rapid spread of invasive genes into a threatened native species. Proceedings of the National Academy of Sciences, 107(8), 3606-3610. DOI: 10.1073/pnas.0911802107
Researchers have established to a more than reasonable degree that fat is important in longevity and aging. A compelling experiment in mice, for example, demonstrates that less visceral fat means a longer life. Then we have the link between fat and chronic inflammation, and the strong correlations between excess fat tissue and all of the common age-related conditions. Given all of this evidence, it shouldn't be surprising that at least some of those researchers interested in slowing down the agi........ Read more »
Enns LC, & Ladiges W. (2010) Protein kinase A signaling as an anti-aging target. Ageing research reviews. PMID: 20188216
You’d think that recognising faces is one of those things that we all do well, or at least the vast majority of us do, yet in practice our ability to do this varies.
Recent twin studies present evidence that face recognition is heritable and is a distinct cognitive task in it’s own right.
At one end of [...]... Read more »
Wilmer, J., Germine, L., Chabris, C., Chatterjee, G., Williams, M., Loken, E., Nakayama, K., & Duchaine, B. (2010) Human face recognition ability is specific and highly heritable. Proceedings of the National Academy of Sciences. DOI: 10.1073/pnas.0913053107
The issue of land use change is a complex, with many factors being important historically, such as
population growth (more land required for more people)
technology (e.g., automobiles made suburban expansion feasible)
economics (cheaper land and rents in suburbs compared to cities)
policy (things like 30-yr mortgages, mortgage insurance, and FHA loans had a large impact on urban sprawl [...]... Read more »
McDonald, R., Forman, R., & Kareiva, P. (2010) Open Space Loss and Land Inequality in United States' Cities, 1990–2000. PLoS ONE, 5(3). DOI: 10.1371/journal.pone.0009509
A randomized controlled trial of using NT-proBNP to guide treatment shows that targeting a clinical score also reduced mortality as compared to usual care and the reduction was similar to the use of the NT-proBNP.... Read more »
Lainchbury JG, Troughton RW, Strangman KM, Frampton CM, Pilbrow A, Yandle TG, Hamid AK, Nicholls MG, & Richards AM. (2009) N-terminal pro-B-type natriuretic peptide-guided treatment for chronic heart failure: results from the BATTLESCARRED (NT-proBNP-Assisted Treatment To Lessen Serial Cardiac Readmissions and Death) trial. Journal of the American College of Cardiology, 55(1), 53-60. PMID: 20117364
My post about fluorescent rabbits is gaining a momentum on the Flickr group 'Bunny Lovers Unite' and in the Rabbitmatch's blog. Most people ask itself: WHY making fluorescent bunnies? And others feel outraged.
Animal research is long debated, and my hope is that the development of new reporter probes would allow to reconsider current research protocols while increasing the scientific significance of the experiments done, this is the focus of my current research. Here, a take opportunity of this........ Read more »
Ciana, P., Raviscioni, M., Mussi, P., Vegeto, E., Que, I., Parker, M., Lowik, C., & Maggi, A. (2002) In vivo imaging of transcriptionally active estrogen receptors. Nature Medicine, 9(1), 82-86. DOI: 10.1038/nm809
Maggi A, & Rando G. (2009) Reporter mice for the study of intracellular receptor activity. Methods in molecular biology (Clifton, N.J.), 307-16. PMID: 19763513
Predicting the future is always difficult. Who could have known in the year 1775 that 100 years from then, ships and trains powered by coal would allow people to circle the earth in weeks rather than years? Who could have predicted that in another 100 years, the human voice—and moving images—would be able travel that [...]... Read more »
Puliafito, S., Puliafito, J., & Grand, M. (2008) Modeling population dynamics and economic growth as competing species: An application to CO2 global emissions. Ecological Economics, 65(3), 602-615. DOI: 10.1016/j.ecolecon.2007.08.010
Here is some more groovy stuff - Scientific American just alerted us to a new article in J Neuroscience. It is right up Charles Spence’s alley but I am stealing his thunder by passing it on now. Charles showed in humans that potato crisps taste better when you hear a crackling noise (I think he might have [...]... Read more »
Wesson DW, & Wilson DA. (2010) Smelling sounds: olfactory-auditory sensory convergence in the olfactory tubercle. The Journal of neuroscience : the official journal of the Society for Neuroscience, 30(8), 3013-21. PMID: 20181598
Have you ever been walking through the forest and thought to yourself, “Damn, its loud here…it’s really, really hard to hear anything anybody else is saying”? Well, maybe that’s what prompted Terry J. Ord and Judy A. Stamps, respectively from Harvard and UC Davis to investigate lizard exercise routines.
You ask: What do lizard calisthenics and [...]... Read more »
Ord TJ, & Stamps JA. (2008) Alert signals enhance animal communication in "noisy" environments. Proceedings of the National Academy of Sciences of the United States of America, 105(48), 18830-5. PMID: 19033197
Capitalists beware. No less a journal than Nature has just published a paper proving conclusively that the human brain is a Communist, and that it's plotting the overthrow of the bourgeois order and its replacement by the revolutionary Dictatorship of the Proletariat even as we speak.Kind of. The article, Neural evidence for inequality-averse social preferences, doesn't mention the C word, but it does claim to have found evidence that people's brains display more egalitarianism than people thems........ Read more »
Tricomi E, Rangel A, Camerer CF, & O'Doherty JP. (2010) Neural evidence for inequality-averse social preferences. Nature, 463(7284), 1089-91. PMID: 20182511
Anyone in the skeptical and atheist community who hasn't heard of the row that erupted over changes to richarddawkins.net forum probably still uses a 56K modem and a dialup connection.
This post summarises the fallout and explores the issue of online communities: are they real or illusory?... Read more »
Haythornwaite, C. (2008) Chapter 9: Social Networks and Community, Oxford handbook of internet psychology – Edited by Adam Joinson. British Journal of Educational Technology, 39(3), 561-562. DOI: 10.1111/j.1467-8535.2008.00855_4.x
Please welcome Laurel Mylonas-Orwig, author of today’s post and a new contributor to the blog!
Every two years, the best athletes in the world gather to compete in the modern Olympic Games. Against a backdrop of sand or snow, these seemingly superhuman competitors push their bodies to perform feats that would be impossible for the average [...]... Read more »
Svensson, E., Black, H., Dugger, D., Tripathy, S., Goldwasser, E., Hao, Z., Chu, L., & Leiden, J. (1997) Long-Term Erythropoietin Expression in Rodents and Non-Human Primates Following Intramuscular Injection of a Replication-Defective Adenoviral Vector. Human Gene Therapy, 8(15), 1797-1806. DOI: 10.1089/hum.1997.8.15-1797
Remember those perhaps gross but cool insect jewelry artists I mentioned before? Now, their incredible tube-making skill might be used in an entirely different field: medicine.Dr. Russell Stewart, an assistant professor at the University of Utah, has been studying natural adhesives for years. He was drawn to the caddisfly because it's one of the few creatures in this world to have accomplished a very difficult feat: it sticks things together underwater.Creating an adhesive that works when wet is........ Read more »
Stewart, R., & Wang, C. (2010) Adaptation of Caddisfly Larval Silks to Aquatic Habitats by Phosphorylation of H-Fibroin Serines. Biomacromolecules, 2147483647. DOI: 10.1021/bm901426d
The superficial summary is that depression is an evolutionary adaptation, and that is still helping us solve problems in modern society. Is this true? These are two very distinct claims and while each may have some merit, saying it like that may obscure as much as it enlightens. ... Read more »
Andrews, P., & Thomson, J. (2009) The bright side of being blue: Depression as an adaptation for analyzing complex problems. Psychological Review, 116(3), 620-654. DOI: 10.1037/a0016242
Fruit fly behavior mapped, resilience theory in an urban setting, changing the universe’s birthdate and genetic diversity in an all-female species. Here are extra news stories and studies on ecological science for the month of February.... Read more »
Siebeck, U., Parker, A., Sprenger, D., Mäthger, L., & Wallis, G. (2010) A Species of Reef Fish that Uses Ultraviolet Patterns for Covert Face Recognition. Current Biology. DOI: 10.1016/j.cub.2009.12.047
Lutes, A., Neaves, W., Baumann, D., Wiegraebe, W., & Baumann, P. (2010) Sister chromosome pairing maintains heterozygosity in parthenogenetic lizards. Nature. DOI: 10.1038/nature08818
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