Post List

  • December 28, 2010
  • 10:58 AM

Denisova the Menace II: Nuclear story

by zacharoo in Lawn Chair Anthropology

Earlier this year, I discussed the publication of a mitochondrial DNA study from a 50,000 year old pinky bone from Denisova in Siberia. The big story there was that the mtDNA of this specimen was twice as divergent (different) from modern humans as Neandertal mtDNA. This suggested to researchers that there was this rogue human group (some [not I] might say 'species') running around Eurasia around the time of the Upper Paleolithic.
Well now they've sequenced the nuclear genome of one of a Denisov........ Read more »

Green, R., Krause, J., Briggs, A., Maricic, T., Stenzel, U., Kircher, M., Patterson, N., Li, H., Zhai, W., Fritz, M.... (2010) A Draft Sequence of the Neandertal Genome. Science, 328(5979), 710-722. DOI: 10.1126/science.1188021  

Reich D, Green RE, Kircher M, Krause J, Patterson N, Durand EY, Viola B, Briggs AW, Stenzel U, Johnson PL.... (2010) Genetic history of an archaic hominin group from Denisova Cave in Siberia. Nature, 468(7327), 1053-60. PMID: 21179161  

  • December 28, 2010
  • 08:07 AM

Rich Condit reminisces

by Vincent Racaniello in virology blog

On my recent trip to record TWiV #111 at Florida Gulf Coast University, I visited Rich Condit in Gainesville. There he told me a story about how the bacteriophage T7 polymerase/promoter system was developed. It’s an interesting tale that demonstrates how important scientific advances often have convoluted roots. You can watch the video below or [...]... Read more »

  • December 28, 2010
  • 07:00 AM

Echinacea for Colds and the Flu

by Scott in Science-Based Pharmacy

Colds and the flu (influenza) are among the most frequent and universal illnesses we all experience. Yet we don’t have any truly effective treatments for them. Sure, there are plenty of products available to treat the symptoms. And there are vaccines and some prescription treatments for influenza, which have modest effects.  But it would be nice if there was something that reliably [...]... Read more »

Barrett B, Brown R, Rakel D, Mundt M, Bone K, Barlow S, & Ewers T. (2010) Echinacea for treating the common cold: a randomized trial. Annals of internal medicine, 153(12), 769-77. PMID: 21173411  

  • December 28, 2010
  • 07:00 AM

Completely Automated Public Turing-test-to-tell Computers and Humans Apart

by David Bradley in Sciencetext

Web sites, services, and apps everywhere often require a user login before you can use the service and even once you’re logged in, there’s often an additional step you must take to prove that you are human, rather than a spam bot or other computer script up to mischief. The device is commonly known as [...]Post from: David Bradley's Sciencetext Tech TalkCompletely Automated Public Turing-test-to-tell Computers and Humans Apart
... Read more »

Brian M. Powell, Adam C. Day, Richa Singh, Mayank Vatsa, & Afzel Noore. (2010) Image-based face detection CAPTCHA for improved security. Int. J. Multimedia Intelligence and Security, 1(3), 269-284. info:/

  • December 28, 2010
  • 06:00 AM

When Is A Placebo Not A Placebo?

by Neuroskeptic in Neuroskeptic

Irving Kirsch, best known for that 2008 meta-analysis allegedly showing that "Prozac doesn't work", has hit the headlines again.This time it's a paper claiming that something does work. Actually Kirsch is only a minor author on the paper by Kaptchuck et al: Placebos without Deception.In essence, they asked whether a placebo treatment - a dummy pill with no active ingredients - works even if you know that it's a placebo. Conventional wisdom would say no, because the placebo effect is driven by th........ Read more »

Kaptchuk, T., Friedlander, E., Kelley, J., Sanchez, M., Kokkotou, E., Singer, J., Kowalczykowski, M., Miller, F., Kirsch, I., & Lembo, A. (2010) Placebos without Deception: A Randomized Controlled Trial in Irritable Bowel Syndrome. PLoS ONE, 5(12). DOI: 10.1371/journal.pone.0015591  

  • December 28, 2010
  • 03:27 AM

Narwhal: Unicorns of the Sea

by beredim in Strange Animals

Also known as the "unicorn of the ocean," the narwhal (Monodon monoceros) is one of the rarest and strangest whales of the world. These elusive and mysterious creatures, are best known for their horn-like tusk on their faces. The tusk is actually an enlarged tooth. Some Narwhals (about 1 in 500) even have two tusks !... Read more »

Nweeia MT, Eichmiller FC, Hauschka PV, Tyler E, Mead JG, Potter CW, Angnatsiak DP, Richard PR, Orr JR, & Black SR. (2012) Vestigial tooth anatomy and tusk nomenclature for monodon monoceros. Anatomical record (Hoboken, N.J. : 2007), 295(6), 1006-16. PMID: 22467529  

Nweeia MT, Eichmiller FC, Hauschka PV, Donahue GA, Orr JR, Ferguson SH, Watt CA, Mead JG, Potter CW, Dietz R.... (2014) Sensory ability in the narwhal tooth organ system. Anatomical record (Hoboken, N.J. : 2007), 297(4), 599-617. PMID: 24639076  

Laidre, K., & Heide-Jorgensen, M. (2005) Winter feeding intensity of narwhals. Marine Mammal Science, 21(1), 45-57. DOI: 10.1111/j.1748-7692.2005.tb01207.x  

Watkins, W. (1971) Underwater Sounds of Monodon (Narwhal). The Journal of the Acoustical Society of America, 49(2B), 595. DOI: 10.1121/1.1912391  

Williams, Terrie M.; Noren, Shawn R.; Glenn, Mike. (2011) Extreme physiological adaptations as predictors of climate-change sensitivity in the narwhal, Mondon monceros. Marine Mammal Science. info:/10.1111/j.1748-7692.2010.00408.x

Laidre, K., & Heide-Jørgensen, M. (2005) Arctic sea ice trends and narwhal vulnerability. Biological Conservation, 121(4), 509-517. DOI: 10.1016/j.biocon.2004.06.003  

  • December 28, 2010
  • 01:32 AM


by Dr Shock in Dr Shock MD PhD

Raw Oysters, especially ‘wild’, are excellent sources of several minerals, including iron, zinc and selenium, which are often low in the modern diet. They are also an excellent source of Vitamin B12. Oysters are considered the healthiest when eaten raw on the half shell.
A search on PubMed also reveals that eating these creatures can be [...]

Related posts:Wine is Healthy
SurgeXperience, Grand Round at Buckeye Surgeon
... Read more »

  • December 28, 2010
  • 01:00 AM

How a change of gaze affects the eye optics?

by Pablo Artal in Optics confidential

Discover how your change in the direction of gaze can affect the optical properties of the eye... and more.... Read more »

Prado, P., Arines, J., Bará, S., Manzanera, S., Mira-Agudelo, A., & Artal, P. (2009) Changes of ocular aberrations with gaze. Ophthalmic and Physiological Optics, 29(3), 264-271. DOI: 10.1111/j.1475-1313.2009.00652.x  

  • December 27, 2010
  • 10:51 PM

Meme Theory Today (NSFW)

by Neurobonkers in Neurobonkers

A look at how meme theory can explain the wide spread misquotation of it's own "inventor" Richard Dawkins.... Read more »

  • December 27, 2010
  • 09:42 PM

Was There Any Cannibalism during the “Great Drought”?

by teofilo in Gambler's House

The best-known examples of probably cannibalism in the prehistoric Southwest all cluster in a very short period of time and in a relatively small geographic area: around AD 1150 in the area surrounding the modern town of Cortez, Colorado.  Perhaps the most solidly documented of these assemblages is the one at Cowboy Wash on the [...]... Read more »

  • December 27, 2010
  • 07:37 PM

Why are the letters "z" and "x" so popular in drug names?

by The Neurocritic in The Neurocritic

Freelance medical and science writer Rob Stepney noticed the rapid growth of "x" and "z"-named products included in the British National Formulary (BNF). So for the Christmas 2010 issue of BMJ (Stepney, 2010), he investigated this phenomenon:Of 1436 products added to the BNF between 1986 and 2005, more than a fifth had names that began with z or x or contained a prominent x or z within them. In 1986, only 19 branded drugs began with one of these letters. Over the next two decades, the numbe........ Read more »

  • December 27, 2010
  • 07:20 PM

Genetic Propensity to Lupus Affords Protection Against Cerebral Malaria

by Michael Long in Phased

Genes which favor the development of lupus impart protection against a deadly variant of malaria in mice.... Read more »

Waisberg, M, Tarasenko, T, Vickers, B. K., Scott, B. L., Willcocks, L. C., Molina-Cruz, A, Pierce, M. A., Huang, C.-y., Torres-Velez, F. J., Smith, K. G. C.... (2010) Genetic susceptibility to systemic lupus erythematosus protects against cerebral malaria in mice. Proceedings of the National Academy of Sciences. info:/10.1073/pnas.1017996108

  • December 27, 2010
  • 06:58 PM

Understand Juror Bias, But Bet On The Evidence

by Dr. Ken Broda-Bahm in Persuasive Litigator

By: Dr. Ken Broda-Bahm - As closing arguments finished in a recent employment jury trial that I sat through, the defense team and I felt, predictably, that we had the overwhelming weight of evidence on our side of the case. But still, we worried as the jury filed in to deliberate. We had faced a Plaintiff's case based on the single simple appeal that a big heartless company will always try to squash the little guy and cover up its tracks in the process, and supported that narrative with nothing ........ Read more »

Joshua Warren, Deanna Kuhn . (2010) How do jurors argue with one another?. Judgment and Decision Making, 5(1), 64-71. info:/

  • December 27, 2010
  • 04:03 PM

Strawberries, Chocolate and Open Access Genomics

by Iddo Friedberg in Byte Size Biology

Nature Genetics seems to have taken a page from the Food Network Magazine by timing two publications to the annual obsession with festive foods among many, NG readership included. I am talking about the genomes of the Strawberry and of the Cocoa plants. Both are important crops, both are components of luxurious eating. Both papers are comprehensive reports, which give no immediate new insights into the biology of either plant but whose data can be hopefully used later to the advantage of crop........ Read more »

Argout, X., Salse, J., Aury, J., Guiltinan, M., Droc, G., Gouzy, J., Allegre, M., Chaparro, C., Legavre, T., Maximova, S.... (2010) The genome of Theobroma cacao. Nature Genetics. DOI: 10.1038/ng.736  

Shulaev, V., Sargent, D., Crowhurst, R., Mockler, T., Folkerts, O., Delcher, A., Jaiswal, P., Mockaitis, K., Liston, A., Mane, S.... (2010) The genome of woodland strawberry (Fragaria vesca). Nature Genetics. DOI: 10.1038/ng.740  

  • December 27, 2010
  • 02:40 PM

Paying Attention To Reading and Math

by APS Daily Observations in Daily Observations

Children with ADHD often have more difficulties on math and reading tests compared to their peers. That’s not surprising in itself. A new twin study published in Psychological Science is ... Read more »

Hart, S.A., Petrill, S.A., Willcutt, E., Thompson, L.A., Schatschneider, C., Deater-Deckard, K., & Cutting, L.E. (2010) Exploring how symptoms of attention-deficit/hyperactivity disorder are related to reading and mathematics performance: general genes, general environments. Psychological science : a journal of the American Psychological Society / APS, 21(11), 1708-15. PMID: 20966487  

  • December 27, 2010
  • 02:20 PM

Managers’ embeddedness in the organization may be detrimental to their career development activity

by Rebecca Quereshi in Occ Psy Dot Com

When organizations attempt to retain their best managers, by firmly embedding them in the organization, this may intuitively appear to be an effective strategy. It sounds like a win-win situation for both parties: The managers are fortunate enough to work in an environment that affords them high person-organization fit, within an organization that encourages good contact among members of the organization. This increases the sacrifice necessary if the manager were to leave the organization. Conse........ Read more »

  • December 27, 2010
  • 10:15 AM

Are the old folks holding us back?

by Christina Pikas in Christina's LIS Rant

We’ve been hearing a lot about how hard it is to get a tenure track job – arguably harder even than it was during other economic recessions. We’ve also been hearing about how the age of NIH PIs is going up. I guess the age at first award is going up as well as the [...]... Read more »

  • December 27, 2010
  • 09:37 AM

explaining the origins of dark matter. or not.

by Greg Fish in weird things

Ordinary baryonic matter, the stuff from which living things, planets, stars, and galaxies are composed, is just a bit player in the grand scale of things. Accounting for about 4.6% of the universe’s mass and energy content, it’s easily overshadowed by dark matter, the invisible clumps of something which creates gravitational lenses and lets spiral [...]... Read more »

  • December 27, 2010
  • 08:48 AM

Double life of bacterial elongation factor EF-Tu

by Vasili Hauryliuk in stringent response

Protein biosyntheses is performed by the ribosome and is assisted by a large number of accessory molecules, with several of them belonging to the GTPase class. EF-Tu is a GTPase which is responsible for bringing the amynoacyl-tRNA to the ribosome, and it is one of the most abundant proteins in bacteria.So abundant, in fact, that it is impossible to explain this abundance by EF-Tu's role in translation. And indeed, recent microscopy investigations has shown how EF-Tu works as a part of bacterial ........ Read more »

Defeu Soufo HJ, Reimold C, Linne U, Knust T, Gescher J, & Graumann PL. (2010) Bacterial translation elongation factor EF-Tu interacts and colocalizes with actin-like MreB protein. Proceedings of the National Academy of Sciences of the United States of America, 107(7), 3163-8. PMID: 20133608  

Vats P, & Rothfield L. (2007) Duplication and segregation of the actin (MreB) cytoskeleton during the prokaryotic cell cycle. Proceedings of the National Academy of Sciences of the United States of America, 104(45), 17795-800. PMID: 17978175  

  • December 27, 2010
  • 07:19 AM

2010 – twelve months of great science

by Joerg Heber in All That Matters

The past year has been a great year for science with major advances in several areas. Too many exciting results to mention here. Instead, to reflect about the past year I have chosen a representative paper for each month of the year that I hope can serve as an example of the great science going [...]... Read more »

Chuang, T., Allan, M., Lee, J., Xie, Y., Ni, N., Bud'ko, S., Boebinger, G., Canfield, P., & Davis, J. (2010) Nematic Electronic Structure in the "Parent" State of the Iron-Based Superconductor Ca(Fe1-xCox)2As2. Science, 327(5962), 181-184. DOI: 10.1126/science.1181083  

Lin, Y., Dimitrakopoulos, C., Jenkins, K., Farmer, D., Chiu, H., Grill, A., & Avouris, P. (2010) 100-GHz Transistors from Wafer-Scale Epitaxial Graphene. Science, 327(5966), 662-662. DOI: 10.1126/science.1184289  

Kelzenberg, M., Boettcher, S., Petykiewicz, J., Turner-Evans, D., Putnam, M., Warren, E., Spurgeon, J., Briggs, R., Lewis, N., & Atwater, H. (2010) Enhanced absorption and carrier collection in Si wire arrays for photovoltaic applications. Nature Materials. DOI: 10.1038/nmat2635  

Ergin, T., Stenger, N., Brenner, P., Pendry, J., & Wegener, M. (2010) Three-Dimensional Invisibility Cloak at Optical Wavelengths. Science, 328(5976), 337-339. DOI: 10.1126/science.1186351  

Yu, X., Onose, Y., Kanazawa, N., Park, J., Han, J., Matsui, Y., Nagaosa, N., & Tokura, Y. (2010) Real-space observation of a two-dimensional skyrmion crystal. Nature, 465(7300), 901-904. DOI: 10.1038/nature09124  

Chadov, S., Qi, X., Kübler, J., Fecher, G., Felser, C., & Zhang, S. (2010) Tunable multifunctional topological insulators in ternary Heusler compounds. Nature Materials, 9(7), 541-545. DOI: 10.1038/nmat2770  

Bae, S., Kim, H., Lee, Y., Xu, X., Park, J., Zheng, Y., Balakrishnan, J., Lei, T., Ri Kim, H., Song, Y.... (2010) Roll-to-roll production of 30-inch graphene films for transparent electrodes. Nature Nanotechnology, 5(8), 574-578. DOI: 10.1038/NNANO.2010.132  

MAIMAN, T. (1960) Stimulated Optical Radiation in Ruby. Nature, 187(4736), 493-494. DOI: 10.1038/187493a0  

Kim, R., Kim, D., Xiao, J., Kim, B., Park, S., Panilaitis, B., Ghaffari, R., Yao, J., Li, M., Liu, Z.... (2010) Waterproof AlInGaP optoelectronics on stretchable substrates with applications in biomedicine and robotics. Nature Materials, 9(11), 929-937. DOI: 10.1038/nmat2879  

Wunderlich, J., Park, B., Irvine, A., Zarbo, L., Rozkotova, E., Nemec, P., Novak, V., Sinova, J., & Jungwirth, T. (2010) Spin Hall Effect Transistor. Science, 330(6012), 1801-1804. DOI: 10.1126/science.1195816  

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