One of the tastiest things I can think of is Jell-O—and just in time to celebrate the Second Annual Jell-O Mold Competition, comes a bit of research from the ACS journal, Analytical Chemistry. The article, "Using Inexpensive Jell-O Chips for...... Read more »
Yang, C., Ouellet, E., & Lagally, E. (2010) Using Inexpensive Jell-O Chips for Hands-On Microfluidics Education. Analytical Chemistry, 2147483647. DOI: 10.1021/ac902926x
Dogs that have been trained to detect an invasive weed are better at finding the plants than humans, a new report says.
Invasive plant managers often face the tough task of wiping out an entire species from an area. But small or rare plants can elude notice, thwarting efforts at eradication. To track down those […] Read More »... Read more »
Goodwin, K.M., Engel, R.E., & D.K. Weaver. (2010) Trained dogs outperform human surveyors in the detection of rare spotted knapweed (Centaurea stoebe). Invasive Plant Science and Management, 3(2), 113-121. DOI: 10.1614/IPSM-D-09-00025.1
In the paper Dark Matter: A Primer Garrett and Dudagives give a nice historical background to the accumulating evidence for dark matter. Lets go through the history they lay out.
1. J. H. Oort: Astronomers have come to tust what is known as the mass to light ratio, M/L, that does a good job telling you what the mass of luminous matter should be based off of the luminosity of that matter.
... Read more »
To some people, a volcanic eruption means “Ahh! Run! Hot Lava!” But to others, it means “SCIENCE!” To those studying hydrothermal vent communities, that is (and a wide berth of geologists). Hydrothermal vents are cracks in the seafloor formed when tectonic plates spread apart, which spew out hot, mineral-rich water from the interior of the [...]... Read more »
Mullineaux, L., Adams, D., Mills, S., & Beaulieu, S. (2010) Larvae from afar colonize deep-sea hydrothermal vents after a catastrophic eruption. Proceedings of the National Academy of Sciences, 107(17), 7829-7834. DOI: 10.1073/pnas.0913187107
By now, readers of Obesity Panacea have hopefully learned that excess weight is not directly predictive of health risk, and that excess fat mass is not in itself unhealthy. Recall that approximately 30% of individuals who are classified as obese by their body weight turn out to be metabolically healthy, and in fact seem not to get much metabolic benefit (or may even get worse) when they lose weight. Also consider that individuals who have NO fat tissue (e.g. lipodystrophy) have extremely elevat........ Read more »
McLaughlin, T., Liu, T., Yee, G., Abbasi, F., Lamendola, C., Reaven, G., Tsao, P., Cushman, S., & Sherman, A. (2009) Pioglitazone Increases the Proportion of Small Cells in Human Abdominal Subcutaneous Adipose Tissue. Obesity. DOI: 10.1038/oby.2009.380
If I want you to give time or money to my cause, I'll say your sacrifice is for "people just like you, just like me," for "communities like yours, all across America," or, as Mary Tyler Moore once wrote, for "fascinating beings with complex social interactions, long childhoods and awkward adolescences" (her subject was lobsters—so human-like, she said, they even walk "claw-in-claw" on the seafloor). Feelings of kinship promote feelings of kindness, as marketers know. Last week, t........ Read more »
De Dreu, C., Greer, L., Handgraaf, M., Shalvi, S., Van Kleef, G., Baas, M., Ten Velden, F., Van Dijk, E., & Feith, S. (2010) The Neuropeptide Oxytocin Regulates Parochial Altruism in Intergroup Conflict Among Humans. Science, 328(5984), 1408-1411. DOI: 10.1126/science.1189047
Feldman, R., Weller, A., Zagoory-Sharon, O., & Levine, A. (2007) Evidence for a Neuroendocrinological Foundation of Human Affiliation: Plasma Oxytocin Levels Across Pregnancy and the Postpartum Period Predict Mother-Infant Bonding. Psychological Science, 18(11), 965-970. DOI: 10.1111/j.1467-9280.2007.02010.x
Hurlemann, R., Patin, A., Onur, O., Cohen, M., Baumgartner, T., Metzler, S., Dziobek, I., Gallinat, J., Wagner, M., Maier, W.... (2010) Oxytocin Enhances Amygdala-Dependent, Socially Reinforced Learning and Emotional Empathy in Humans. Journal of Neuroscience, 30(14), 4999-5007. DOI: 10.1523/JNEUROSCI.5538-09.2010
APPLYING for a job? The weight of the clipboard to which your CV is attached may influence your chances of getting it. Negotiating a deal? Sitting in a hard chair may lead you to drive a harder bargain. Those are two of the surprising conclusions of a study published in today's issue of Science, which shows that the physical properties of objects we touch can unconsciously influence our first impressions of other people and the decisions we make about them.
Josh Ackerman of the Sloan School of ........ Read more »
Ackerman, J., Nocera, C., & Bargh, J. (2010) Incidental Haptic Sensations Influence Social Judgments and Decisions. Science, 328(5986), 1712-1715. DOI: 10.1126/science.1189993
Although the paper addresses Tanzanian lions, this is a photograph of a Namibian lion Starting some years ago, we began to hear about revisions of the standard models of lion behavioral biology coming out of Craig Packer's research in the Serengeti. One of the most startling findings, first shown (if memory serves) as part of a dynamic optimization model and subsequently backed up with a lot of additional information, is the idea that lions do not benefit by living in a group with respect t........ Read more »
Mosser, A., & Packer, C. (2009) Group territoriality and the benefits of sociality in the African lion, Panthera leo. Animal Behaviour. DOI: 10.1016/j.anbehav.2009.04.024
Mammals have long been characterized as the underdogs of the Mesozoic world. They diversified in habitats ecologically dominated by dinosaurs, but, even though most were small, they did not simply cower in their burrows until the non-avian dinosaurs were wiped out 65 million years ago. In fact, Mesozoic mammals were more varied in anatomy and [...]... Read more »
LONGRICH, N., & RYAN, M. (2010) Mammalian tooth marks on the bones of dinosaurs and other Late Cretaceous vertebrates. Palaeontology. DOI: 10.1111/j.1475-4983.2010.00957.x
by gkobs in Promega Connections
The analysis of functional protein typically requires lengthy laborious cell based protein expression that can be complicated by the lack of stability or solubility of the purified protein. Cell free protein expression eliminates the requirement for cell culture thus providing quick access to the protein of interest. A recent publication demonstrated the feasibility of using cell free expression and the HaloTag technology to express and capture a fusion protein for the rapid screening of protein........ Read more »
Leippe DM, Zhao KQ, Hsiao K, & Slater MR. (2010) Cell-free expression of protein kinase a for rapid activity assays. Analytical chemistry insights, 25-36. PMID: 20520741
As most smokers are well aware, smoking cessation is often accompanied by a variable amount of weight gain, and there is some evidence that some people (particularly young women) primarily smoke to control their appetite and weight.
Indeed, as blogged previously, the progress on fighting tobacco in the US may be eroded by the gains [...]... Read more »
Sen A, Entezarkheir M, & Wilson A. (2010) Obesity, smoking, and cigarette taxes: Evidence from the Canadian Community Health Surveys. Health policy (Amsterdam, Netherlands). PMID: 20570008
How does one species get a bigger brain than another?
A while ago, I wrote about a paper that argued that genes that define boundaries in the nervous system seemed to be responsible for differing brain structures in cichlid fish. This seemed to explain the data better than a competing hypothesis, which was that the differences in brain size were caused by the length of time the brain spent forming neurons (neurogenesis). A forthcoming paper by Charvet and Striedter suggest a third possibility.
........ Read more »
Charvet, C., & Striedter, G. (2010) Bigger brains cycle faster before neurogenesis begins: A comparison of brain development between chickens and bobwhite quail. Proceedings of the Royal Society B: Biological Sciences. DOI: 10.1098/rspb.2010.0811
A paracentesis procedure is often performed in the Emergency Department to rule a patient out for spontaneous bacterial peritonitis (SBP). Do you check coagulation studies before performing the procedure? How comfortable do you feel that the patient has SBP with an ascites WBC 500 cells/microliter or ascites PMN 250 cells/microliter?This installment of the Paucis Verbis (In a Few Words) e-card series provides an evidence-based review of the literature on topics related to the paracentesis proc........ Read more »
Wilkerson, R., & Sinert, R. (2009) The Use of Paracentesis in the Assessment of the Patient With Ascites. Annals of Emergency Medicine, 54(3), 465-468. DOI: 10.1016/j.annemergmed.2008.09.005
It’s Friday, and what better way to get into the mood for beer hour than to talk about death? To make sure that the mood doesn’t get too lugubrious, let’s stick to the death of entities that are unlikely to remind you of anyone you know, such as single cells. This video shows HeLa cells undergoing apoptosis, from work described in Spencer SL, Gaudet S, Albeck JG, Burke JM, Sorger PK. 2009. Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis. Nature 459........ Read more »
Spencer SL, Gaudet S, Albeck JG, Burke JM, & Sorger PK. (2009) Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis. Nature, 459(7245), 428-32. PMID: 19363473
Whether it's the awkward coincidence of meeting your boss in the supermarket aisle or a humourless joke by a new date, what would we do without the fake smile? It's not that the fake is all that convincing. Apparently most adults can tell the difference - the lopsidedness of the mouth and lack of creasing around the eyes gives it away. But the fact that the faker is trying their best to send a positive signal somehow saves face all round. Well, most of the time anyway.
Of course when you're dea........ Read more »
Gosselin, P., Perron, M., & Maassarani, R. (2009) Children's ability to distinguish between enjoyment and non-enjoyment smiles. Infant and Child Development. DOI: 10.1002/icd.648
Carbohydrate-restricted eating is slowly gaining mainstream acceptance as treatment for type 2 diabetes and metabolic syndrome. I thought it would be useful to present one of the watershed reports that summarize the potential benefits. The article is from 2008. Among the co-authors are some of the brightest names in this field: Richard K. Bernstein, Annika Dahlqvist, Eugene [...]... Read more »
Accurso A, Bernstein RK, Dahlqvist A, Draznin B, Feinman RD, Fine EJ, Gleed A, Jacobs DB, Larson G, Lustig RH.... (2008) Dietary carbohydrate restriction in type 2 diabetes mellitus and metabolic syndrome: time for a critical appraisal. Nutrition , 9. PMID: 18397522
Compared to the low-fat American Heart Association diet, the traditional Mediterranean diet rich in olive oil has more capacity to counteract potentially harmful “free radicals” and “reactive oxygen species” in our bodies, according to researchers at the University of Navarra in Spain.
Our tissues normally contain free radicals and reactive oxygen species, which are intrinsic to cell [...]... Read more »
Razquin, C., Martinez, J., Martinez-Gonzalez, M., Mitjavila, M., Estruch, R., & Marti, A. (2009) A 3 years follow-up of a Mediterranean diet rich in virgin olive oil is associated with high plasma antioxidant capacity and reduced body weight gain. European Journal of Clinical Nutrition, 63(12), 1387-1393. DOI: 10.1038/ejcn.2009.106
Remember the voodoo correlations and double-dipping controversies that rocked the world of fMRI last year? Well, the guys responsible have teamed up and written a new paper together. They are...The paper is Everything you never wanted to know about circular analysis, but were afraid to ask. Our all-star team of voodoo-hunters - Ed "Hannibal" Vul (now styled Professor Vul), Nikolaus "Howling Mad" Kriegeskorte, Russell "B. A. Baracus" Poldrack - provide a good overview of the various issues and ........ Read more »
Kriegeskorte, N., Lindquist, M., Nichols, T., Poldrack, R., & Vul, E. (2010) Everything you never wanted to know about circular analysis, but were afraid to ask. Journal of Cerebral Blood Flow . DOI: 10.1038/jcbfm.2010.86
I have finished my exams. My gods, it feels good. I’m pretty sure I smashed them too. I’m expecting for 6′s – which is slightly disappointing, but I’ll be perked up if there’s a 7 among them (and the possibility does exist). I’ll post after the 7th when results are released. In the mean-time I [...]... Read more »
Stampi, C. (1989) Polyphasic sleep strategies improve prolonged sustained performance: A field study on 99 sailors. Work , 3(1), 41-55. DOI: 10.1080/02678378908256879
As you probably know is Dr Shock completely biased when writing about chocolate especially dark chocolate. He mostly writes about the research with positive results of chocolate on cardiovascular diseases. A recent review included 5 studies of adequate quality for inclusion in a recent meta analysis as well as 8 other peer reviewed studies for [...]
Related posts:Chocolate as Antihypertensive Drug?
Dark Chocolate Improves Coronary Blood Flow
How Much Chocolate is good for your Health?
... Read more »
Egan, B., Laken, M., Donovan, J., & Woolson, R. (2010) Does Dark Chocolate Have a Role in the Prevention and Management of Hypertension?: Commentary on the Evidence. Hypertension, 55(6), 1289-1295. DOI: 10.1161/HYPERTENSIONAHA.110.151522
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