Good news for sheep: scientists have moved a step closer to understanding how a disease-causing worm evades the sheep immune system. Parasitic gastroenteritis (PGE) causes diarrhoea, weight loss and dehydration in sheep and can be fatal. The disease is commonly caused by a nematode worm, Teladorsagia circumcincta, which makes its home in the stomach of [...]... Read more »
Nisbet AJ, Bell NE, McNeilly TN, Knox DP, Maizels RM, Meikle LI, Wildblood LA, Matthews JB. (2010) A macrophage migration inhibitory factor-like tautomerase from Teladorsagia circumcincta (Nematoda: Strongylida). Parasite Immunol., 32(7), 503-511. DOI: 10.1111/j.1365-3024.2010.01215.x
The sea is a dark and often mysterious place, and it's no wonder that the fear and fascination with the marine world has led to more than a few inaccurate claims. The crew over at Southern Fried Science have decided that this week is all about busting pseudoscience and the myths that surround our ocean realm. As it turns out, I'd posted about one of these before. So here, in honor of Ocean of Pseudoscience week, is a repost busting the myth that sharks don't get cancer.
There are a lot of myths........ Read more »
Brem H, & Folkman J. (1975) Inhibition of tumor angiogenesis mediated by cartilage. . J Exp Med, 427-439. DOI: 10.1084/jem.141.2.427
Langer R, & et al. (1976) Isolations of a cartilage factor that inhibits tumor neovascularization. Science, 70-72. DOI: 10.1126/science.935859
Lee A, & Langer R. (1983) Shark cartilage contains inhibitors of tumor angiogenesis. Science, 1185-1187. DOI: 10.1126/science.6193581
Luer CA, & Luer WH. (1982) Acute and chronic exposure of nurse sharks to aflatoxin B1. Federal Proceedings, 925. info:/
Horsman MR, Alsner J, & Overgaard J. (1998) The effect of shark cartilage extracts on the growth and metastatic spread of the SCCVII carcinoma. Acta oncologica (Stockholm, Sweden), 37(5), 441-5. PMID: 9831372
Miller DR, Anderson GT, Stark JJ, Granick JL, & Richardson D. (1998) Phase I/II trial of the safety and efficacy of shark cartilage in the treatment of advanced cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 16(11), 3649-55. PMID: 9817287
Loprinzi CL, Levitt R, Barton DL, Sloan JA, Atherton PJ, Smith DJ, Dakhil SR, Moore DF Jr, Krook JE, Rowland KM Jr.... (2005) Evaluation of shark cartilage in patients with advanced cancer: a North Central Cancer Treatment Group trial. Cancer, 104(1), 176-82. PMID: 15912493
Lu C, Lee JJ, Komaki R, Herbst RS, Feng L, Evans WK, Choy H, Desjardins P, Esparaz BT, Truong MT.... (2010) Chemoradiotherapy with or without AE-941 in stage III non-small cell lung cancer: a randomized phase III trial. Journal of the National Cancer Institute, 102(12), 859-65. PMID: 20505152
Vickers, A. (2004) Alternative cancer cures: "unproven" or "disproven"?. CA: A Cancer Journal For Clinicians, 110-118. DOI: 10.3322/canjclin.54.2.110
Ostrander GK, Cheng KC, Wolf JC, & Wolfe MJ. (2004) Shark cartilage, cancer and the growing threat of pseudoscience. Cancer research, 64(23), 8485-91. PMID: 15574750
Last week I attended Medical Grand Rounds at the University of Alberta Hospital presented by our Faculty’s latest recruit Sangita Sharma (no relation), Professor in Aboriginal and Global Health and newly Endowed Chair in Aboriginal Health.
Sangita, who earned her PhD in nutritional epidemiology from the University of Manchester, UK, comes to Edmonton from the Nutrition [...]... Read more »
Gittelsohn J, Roache C, Kratzmann M, Reid R, Ogina J, & Sharma S. (2010) Participatory research for chronic disease prevention in Inuit communities. American journal of health behavior, 34(4), 453-64. PMID: 20218757
This post is a scholarly addendum to today’s main post, aimed to satisfy the curiosity of my academic readers. I’m going to leave you with an excerpt from an excellent book chapter, “Repetition and Reuse in Child Language Learning,” by Colin Bannard and Elena Lieven. The two take up the question of why Zipfian distributions [...]... Read more »
Ferrer-i-Cancho, R., & Sole, R. V. (2003) Least effort and the origins of scaling in human language. Proceedings of the National Academy of Sciences of the United States of America, 788-791. DOI: 10.1073/pnas.0335980100
Biemann, C. (2007) A Random Text Model for the Generation of Statistical Language Invariants. Proceedings of HLT-NAACL-07, Rochester, NY, USA. info:/
This morning, I scrawled a letter to a friend that began with the following: Spent the weekend at the FyeahFest with a starry-eyed lot of starving hipsters, in vintage hops and wingtips. Had not realized how obvious the effects of doing molly are on the pupils… the droves wandering past had eyes like shining saucers. [...]... Read more »
KW Church,, & WA Gale. (1995) Inverse document frequency (IDF): A measure of deviations from Poisson. In A. et al. (Ed.), NLP using Very Large Corpora. Kluwer Academic Publishers. . info:/
DeLong, K., Urbach, T., & Kutas, M. (2005) Probabilistic word pre-activation during language comprehension inferred from electrical brain activity. Nature Neuroscience, 8(8), 1117-1121. DOI: 10.1038/nn1504
Do you have medical students rotating in your Emergency Department? Are they allowed to document in the medical record?Charting in the medical record is the cornerstone of clinical communication. You document your findings, your clinical reasoning, and management plan. The medical record allows communication amongst providers. Chart documentation is a crucial skill that every medical student should know, as stated by the Association of American Medical Colleges (AAMC). However, there is a growin........ Read more »
Friedman E, Sainte M, & Fallar R. (2010) Taking note of the perceived value and impact of medical student chart documentation on education and patient care. Academic medicine : journal of the Association of American Medical Colleges, 85(9), 1440-4. PMID: 20736671
If something's troubling you, write it down, put it an envelope and seal it. Doing so will help bring you psychological closure. Xiuping Li at NUS Business School asked 80 students to write about a recent decision they regretted. Half of them were then told to seal their written recollection in an envelope. Afterwards, the envelope students felt less negative about the event than control students who just handed in their recollection without an envelope. The finding was replicated with forty fem........ Read more »
Li X, Wei L, & Soman D. (2010) Sealing the emotions genie: the effects of physical enclosure on psychological closure. Psychological science : a journal of the American Psychological Society / APS, 21(8), 1047-50. PMID: 20622143
What is palliative care? Until quite recently, it's something I haven't given much thought. Although there was a highly regarded article on hospice and palliative care by Atul Gawande in last month's New Yorker, I didn't read it or think it applied to my life. All that changed less than two weeks ago, when my father was hospitalized in critical condition after collapsing. First he went to the ER, then the transitional ICU, and finally he was placed in the palliative care unit by the time I arriv........ Read more »
J.S. Temel et al. (2010) Early Palliative Care for Patients with Metastatic Non–Small-Cell Lung Cancer. N Engl J Med, 733-742. info:/10.1056/NEJMoa1000678
Even the most obtuse, right-wing, head-in-the-sand, consumption-driven, anti-environment yob would at least admit that they’ve heard of forest conservation, the plight of whales (more on that little waste of conservation resources later) and climate change. Whether or not they believe these issues are important (or even occurring) is beside the point – the fact that [...]... Read more »
M.L. Thieme, B. Lehner, R. Abell, & J. Matthews. (2010) Exposure of Africa's freshwater biodiversity to a changing climate. Conservation Letters. DOI: 10.1111/j.1755-263X.2010.00120.x
I’m having a problem. I’m an editor for the Dutch/Flemish Journal of Psychiatry. Since I’m a blogger and on twitter and using many more web 2.0 tools I’m supposed to be the expert on web 2.0 and our journal. We’ve revamped our website and the journal is even on twitter. We’re planning presence on Facebook [...]
Related posts:Editing Medical Journals, A Course in Oxford
Twitter, Doctors, Hospitals and Medical Education
Social Media in Health and Medicine: Me........ Read more »
Senoaji Wijaya, Marco Spruit, Wim Scheper, & Johan Versendaal. (2010) Web 2.0-based webstrategies for three different types of organizations. Computers in Human Behavior. info:/10.1016/j.chb.2010.07.041
One noteworthy thing about George Pepper’s interpretations of the effigy vessels found at Pueblo Bonito is his attempt to link them to specific Hopi kachinas. He does find a general similarity in facial and body decoration between one of the partial vessels, found in Room 38, and one kachina and notes at the end of [...]... Read more »
Lekson, S., & Cameron, C. (1995) The abandonment of Chaco Canyon, the Mesa Verde migrations, and the reorganization of the Pueblo world. Journal of Anthropological Archaeology, 184-202. DOI: 10.1006/jaar.1995.1010
I love the Groth and Gurney paper, and not just because it introduced me to http://researchblogging.org/. The authors analyzed 295 blog posts about chemistry and the included citations. In comparison to the usual pieces which deal with science blogging in the scholarly literature, this paper has dealt with a large number of posts. Most of what I've read about science blogging are either opinion articles (Batts et al, 2008), or qualitative research, aka interviews with a small number of bloggers ........ Read more »
Paul Groth, & Thomas Gurney. (2010) Studying Scientific Discourse on the Web Using Bibliometrics: A Chemistry Blogging Case Study. In press. info:/
Sara Kjellberg. (2010) I am a blogging researcher: Motivations for blogging in a scholarly context. First Monday, 15(8). info:other/
Batts, S. A., Anthis, N. J. , & Smith, T. C. (2008) Advancing Science through Conversations: Bridging the Gap between Blogs and the Academy. PLoS Biology, 6(9). DOI: 10.1371/journal.pbio.0060240
Today I would like to introduce a theory developed by Giddens in 1988 about social structures and how it can be used to analyze theories in Supply Chain Management.
Continue reading "Theory about Social Structures"
... Read more »
Pfohl, Hans-Christian, Elbert, Ralf, & Gallus, Philipp. (2007) Implementierung interorganisationaler Managementinstrumente in logistischen Netzwerken: Strukturationstheoretische Analyse der Besonderheiten bei der Implementierung der CargoScoreCard im Kombinierten Verkehr. Logistikmanagement: Analyse, Bewertung und Gestaltung logistischer Systeme, 231-262. info:/
Now, five years later, there's new evidence of the significant, negative impact of Hurricane Katrina on children's mental health. The study "Children as Bellwethers of Recovery" was conducted by researchers from the National Center for Disaster Preparedness at Columbia University's Mailman School of Public Health and was published online by the Journal of Disaster Medicine and Public Health Preparedness.
The results come from a longitudinal study of 1079 families in Louisiana and Mississippi ........ Read more »
Abramson, D. M., Park, Y. S., Stehling-Ariza, T., & Redlener, I. (2010) Children as Bellwethers of Recovery. Disaster Medicine and Public Health Preparedness. info:/10.1001/dmp.2010.7
(Comments are still down, and will be for the next day or two. Sorry. We will try moving the discussion to the WCU facebook page. –PalMD) To people who grew up before the internet, the debate about whether Craigslist should be allowed to post “erotic services” must seem bizarre. But meeting people online, whether for [...]... Read more »
Mary McFarlane, PhD; Sheana S. Bull, PhD, MPH; Cornelis A. Rietmeijer, MD, MPH. (2000) The Internet as a Newly Emerging Risk Environment for Sexually Transmitted Diseases. JAMA, 244(4), 443-446. DOI: 10.1001/jama.284.4.443
McFarlane M, Bull SS, & Rietmeijer CA. (2002) Young adults on the Internet: risk behaviors for sexually transmitted diseases and HIV(1). The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 31(1), 11-6. PMID: 12090960
Centers for Disease Control and Prevention (CDC). (2003) Internet use and early syphilis infection among men who have sex with men--San Francisco, California, 1999-2003. MMWR. Morbidity and mortality weekly report, 52(50), 1229-32. PMID: 14681596
A A Al-Tayyib1, M McFarlane, R Kachur, C A Rietmeijer1. (2009) Finding sex partners on the internet: what is the risk for sexually transmitted infections?. Sexually Transmitted Infections, 216-220. DOI: 10.1136/sti.2008.032631
Originally posted on Cognitive Daily. This is a guest post by David Kerns, one of Greta’s top student writers for Spring 2007. As movie special effects technology improves, more and more live-action shots are being replaced with computer animation. Harry Potter flies across the Quidditch field; Spider-Man swings from web to web through the cityscape [...]... Read more »
Jastorff J, Kourtzi Z, & Giese MA. (2006) Learning to discriminate complex movements: biological versus artificial trajectories. Journal of vision, 6(8), 791-804. PMID: 16895459
An article with a title like “Science’s dead end” seems like an active effort to troll the science blogosphere. Maybe author James Le Fanu has a point, but a quick search raise doubts as fast as you can type. He’s trained as a medical doctor, not a researcher. And he seems to be a cynical one, having written a piece with a similarly apocalyptic title, “The fall of medicine,” for the same magazine over ten years ago.
He outsider’s perspective is apparent in his first paragraph.
F........ Read more »
Anckarsäter H. (2010) Has biology disproved free will and moral responsibility?. Proceedings of the National Academy of Sciences, 107(27). DOI: 10.1073/pnas.1006466107
Brass M, & Haggard P. (2007) To do or not to do: The neural signature of self-control. The Journal of Neuroscience, 27(34), 9141-9145. DOI: 10.1523/jneurosci.0924-07.2007
Cashmore AR. (2010) The Lucretian swerve: The biological basis of human behavior and the criminal justice system. Proceedings of the National Academy of Sciences of the United States of America, 107(10), 4499-4504. info:/10.1073/pnas.0915161107
Hinsen K. (2010) A scientific model for free will is impossible . Proceedings of the National Academy of Sciences of the United States of America. info:/10.1073/pnas.1010609107
James Collins (Boston University, United States) and coworkers have investigated the basis of antibiotic resistance from a communal perspective. This news feature was written on September 5, 2010.... Read more »
Lee H. H., Molla M. N., Cantor C. R., & Collins J. J. (2010) Bacterial charity work leads to population-wide resistance. Nature, 467(7311), 82-5. PMID: 20811456
Okay, I said I would say more about George Pepper’s description of the effigy vessels from Chaco, so here goes. One interesting thing that he notes is that these are the northernmost examples of human effigy vessels found in the Southwest. I believe this is still the case over a hundred years later; in general, [...]... Read more »
VanPool, C. (2003) The Shaman-Priests of the Casas Grandes Region, Chihuahua, Mexico. American Antiquity, 68(4), 696-717. DOI: 10.2307/3557068
VanPool, C., & VanPool, T. (2006) Gender in Middle Range Societies: A Case Study in Casas Grandes Iconography. American Antiquity, 71(1), 53-75. DOI: 10.2307/40035321
Image via Wikipedia I’ve written previously about Maslow’s motivational hierarchy and how that relates to the eight stage evo-devo model. Most people are familiar with the 5 motivational basic needs/motives theory of Maslow, but are not aware that he had later revised it to include eight basic needs/ motives. A recent paper by Krenrick etRating: 0.0/10 (0 votes cast)... Read more »
Douglas T. Kenrick,, Vladas Griskevicius,, Steven L. Neuberg, & Mark Schaller. (2010) Renovating the Pyramid of Needs Contemporary Extensions Built Upon Ancient Foundations. Perspectives on Psychological science. DOI: 10.1177/1745691610369469
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