Post List

  • January 27, 2011
  • 03:16 PM
  • 951 views

Why HisH doesn't fire until it sees the whites of PRFAR's eyes

by Michael Clarkson in Conformational Flux

The enzyme imidazole glycerophosphate synthase (IGPS) can be a bit of a lump. If you bind just one substrate it doesn't do anything, even though its two active sites are separated by more than 30 Å. Only if the second substrate also binds does catalysis actually go at anything like a respectable rate. In a recent paper in Structure researchers from Yale report evidence that this change of pace results from a change in dynamics.


Apo- IGPS from Thermatoga maritima
PDB code: 1GPW
IGPS consists o........ Read more »

  • January 27, 2011
  • 01:54 PM
  • 1,353 views

Are there unintended health effects of genetic engineering?

by Anastasia Bodnar in Biofortified

Francis Thicke, agronomist and organic dairy farmer in Iowa, asks: Do you think there are unanswered questions about the health effects of GE foods? I have heard GE critiques frequently contend that there have been very few feeding trials on the health effects of GE foods, and that in the feeding trials that have been done, the results have raised questions about the safety of GE foods. For starters, what is your opinion Continue reading...... Read more »

  • January 27, 2011
  • 01:28 PM
  • 1,320 views

Citrus call for backup to fight root-destroying pests

by Christie Wilcox in Observations of a Nerd

Citrus fruits are delicious. Their delicate balance of sweetness and tartness is a biochemical masterpiece. It's no wonder that they, of all nature's tasty options, are the highest value fruit crop in terms of international trade, with over 105 million tons produced annually. But these tempting produce face a persistant villain that seeks to destroy their roots; a menace known, cleverly, as the citrus root weevil.

The weevil's grubby larvae feed like maggots on the vital roots of citrus plants........ Read more »

  • January 27, 2011
  • 12:57 PM
  • 1,468 views

Measuring Discrimination…with 9/11

by Rob Mitchum in ScienceLife

It is widely acknowledged that racial or ethnic discrimination can negatively affect a person’s health. But how can a scientist measure this impact? The treatment that a person encounters due to the color of their skin, their language, or their country of origin is likely a chronic stimulus, encountered over their entire life rather than [...]... Read more »

  • January 27, 2011
  • 12:36 PM
  • 2,195 views

Typing vs. Longhand: Does it Affect Your Writing?

by Livia Blackburne in A Brain Scientist's Take on Writing

Do you write longhand or on a computer? How does this affect your writing process? I ran across a study with interesting results.

The researchers wanted to know how computer writing differed from pen and paper writing. They recruited university faculty and graduate students to write two reports, one on a computer and one on pen and paper. The participants were given background information for the reports (about a new system of bank charges and new company regulations) two days beforehand. ........ Read more »

  • January 27, 2011
  • 11:58 AM
  • 1,446 views

Africa’s new, old gray wolf

by DeLene Beeland in Wild Muse

Africa has a new, old wolf. An animal that was previously called a subspecies of the golden jackal in Egypt has now been found to be a very rare relict species hiding in plain sight — an ancient gray wolf line still living today. Previously, it was thought that the Ethiopian wolf (Canis simensis) was [...]... Read more »

Eli Knispel Rueness, Maria Gulbrandsen Asmyhr, Claudio Sillero-Zubiri, David W. Macdonald, Afework Bekele, Anagaw Atickem, Nils Chr. Stenseth. (2011) The Cryptic African Wolf: Canis aureus lupaster Is Not a Golden Jackal and Is Not Endemic to Egypt . PLoS ONE, 6(1). info:/10.1371/journal.pone.0016385

  • January 27, 2011
  • 11:35 AM
  • 2,915 views

Leek Moth in Britain: spread and chemical-free control

by davesbrain in Dave Hubble's ecology spot

Normal 0 false false false EN-GB X-NONE X-NONE ... Read more »

Mason, P.G., Appleby, M., Juneja, S., Allen, J., & Landry, J.-F. (2010) Biology and Development of Acrolepiopsis assectella (Lepidoptera: Acrolepiidae) in Eastern Ontario. The Canadian Entomologist 142(4):393-404. 2010 , 142(4), 393-404. info:/10.4039/n10-026

  • January 27, 2011
  • 11:30 AM
  • 1,497 views

Genomic Imprinting V: DNA methylation and gene silencing

by Jon Wilkins in Lost in Transcription

So, we've already discussed the fact that genomic imprinting is mediated through epigenetic differences between the maternally and paternally inherited gene copies. That is, at an imprinted locus, the maternally inherited allele will have one pattern of epigenetic modifications, while the paternally inherited allele has a different pattern. These differences are first established in the male and female germ lines, when the alleles that will eventually become maternally and paternally derived are........ Read more »

  • January 27, 2011
  • 11:24 AM
  • 479 views

A whole new RNA world

by Katie Pratt in katiephd.com

I was surprised to discover the paper I’m about to present to you came out over a week ago. It didn’t cause much of a splash, yet it details a novel treatment for HIV. Ok, that’s overstating it a little bit, but it’s not far off. In order to explain exactly how this “aptamer-siRNA chimera” [...]... Read more »

Neff, C., Zhou, J., Remling, L., Kuruvilla, J., Zhang, J., Li, H., Smith, D., Swiderski, P., Rossi, J., & Akkina, R. (2011) An Aptamer-siRNA Chimera Suppresses HIV-1 Viral Loads and Protects from Helper CD4 T Cell Decline in Humanized Mice. Science Translational Medicine, 3(66), 66-66. DOI: 10.1126/scitranslmed.3001581  

  • January 27, 2011
  • 11:14 AM
  • 788 views

fMRI Scanning Salmon - Seriously.

by Neuroskeptic in Neuroskeptic

Back in 2009, a crack team of neuroscientists led by Craig Bennett (blog) famously put a dead fish into an MRI scanner and showed it some pictures.They found some blobs of activation - when they used an inappropriately lenient statistical method. Their point, of course, was to draw attention to the fact that you really shouldn't use that method for fMRI. You can read the whole paper here. The Atlantic Salmon who heroically volunteered for the study was no more than a prop. In fact, I believe he ........ Read more »

  • January 27, 2011
  • 11:08 AM
  • 732 views

Psychology's Frenemies

by Jenika in ionpsych

The thorny relationship between neuroscience and clinical psychology... Read more »

  • January 27, 2011
  • 10:30 AM
  • 1,511 views

Legal Protections for Working Women in US Law Might Have Been a Joke

by Richard Landers in NeoAcademic

In a fascinating article in the Industrial-Organizational Psychologist, Scott Highhouse[1] discusses why legal protections provided to women under Title VII of the Civil Rights Act of 1964 might have been included by lawmakers as a joke – or more specifically, as a way to make the bill so ridiculous that it would not pass a [...]


Some related articles on Neo-Academic:The Right to Internet Access
... Read more »

Highhouse, S. (2011) The history corner: Was the addition of sex to Title VII a joke? Two viewpoints. . The Industrial-Organizational Psychologist, 48(3), 102-107. info:/

  • January 27, 2011
  • 08:03 AM
  • 1,431 views

Study: A Complete Stranger Understands You About as Well as Your Spouse Does

by David Berreby in Mind Matters


If you say "it's snowing hard out there," are you annoyed if no one gets up to shovel the walkway? Vexed, are you, by your intimates' inability to see what you meant? Do you think a long love's result should be near-wordless mind-reading? If so, here is some advice derived from the current issue of ...Read More
... Read more »

Savitsky, K., Keysar, B., Epley, N., Carter, T., & Swanson, A. (2011) The closeness-communication bias: Increased egocentrism among friends versus strangers. Journal of Experimental Social Psychology, 47(1), 269-273. DOI: 10.1016/j.jesp.2010.09.005  

  • January 27, 2011
  • 08:00 AM
  • 1,844 views

How Effective is Self-Monitoring in Weight Management?

by Arya M. Sharma in Dr. Sharma's Obesity Notes

One of the key principles of behaviour modification in chronic disease management is self-monitoring. This is why we ask patients with pain to keep a pain diary, patients with diabetes to monitor their glucose levels, patients with hypertension to measure their blood pressure, and patients with asthma to monitor their peak flow.
In obesity management, the [...]... Read more »

Burke LE, Wang J, & Sevick MA. (2011) Self-monitoring in weight loss: a systematic review of the literature. Journal of the American Dietetic Association, 111(1), 92-102. PMID: 21185970  

  • January 27, 2011
  • 07:33 AM
  • 1,209 views

the linguistics of heaven and hell

by Chris in The Lousy Linguist

The value of pop culture data for legitimate research is being put to the test. Exactly what, if anything, can the reality show Big Brother tell us about language change over time?Voice Onset Time is a measure of how long you wait to begin vibrating your vocal folds after you release a stop consonant. Voiced stop consonants like /b/ and /d/ require two things: 1) stop all airflow from escaping the airway by closing the glottis and 2) after the air is released, begin vibrating the glottis (by usi........ Read more »

Max Ban, Peter Graf, & Morgan Sonderegge. (2011) Longitudinal phonetic variation in a closed system. Linguistic Society of America. info:/

  • January 27, 2011
  • 07:00 AM
  • 1,394 views

Why chocolate pudding can turn green

by Colby in nutsci.org

Last night, my girlfriend informed me that she made some instant (sugar free, fat free) chocolate pudding 2 nights before.  When opening the fridge to finish it off, it was green!  I had never heard of this before.  I don’t … Continue reading →... Read more »

  • January 27, 2011
  • 07:00 AM
  • 749 views

Minding mindfulness – what is going on?

by Lorimer Moseley in BodyInMind

Mindfulness is, it seems, in fashion. Every month there seems to be a new TV show or talkback hour on its wondrous curative powers.  It made it into our Christmas Dinner Conversation and I am waiting for the mindfulness-branded t-shirts and environmentally friendly canvas shopping bags to emerge.  Is it really that good? Well, fortunately [...]... Read more »

  • January 27, 2011
  • 07:00 AM
  • 1,224 views

January 27, 2011

by Erin Campbell in HighMag Blog

Just when you think you understand how a gene works…BAM! Alternative splicing shows up and reminds us that there is so much yet to learn, even about a gene as well-studied as formin. Genes get transcribed into RNA, which gets translated into proteins. After transcription of a gene, different regions of RNA called exons and introns are either connected together (exons) or removed (introns) in a process called splicing. Some genes undergo a process called “alternative splicing” that allo........ Read more »

  • January 27, 2011
  • 06:16 AM
  • 2,096 views

Guest post: Awakening stem cells in the brain – glia sound the alarm

by Wellcome Trust in Wellcome Trust Blog

  Stem cells are often hailed for their medical potential, but the cells surrounding them can be just as important and may offer an alterative therapeutic strategy. Professor Andrea Brand and Dr James Chell of the Gurdon Institute, Cambridge, have uncovered the key role of glial cells in controlling stem cell division in the brain. [...]... Read more »

  • January 27, 2011
  • 05:36 AM
  • 1,347 views

Apocalyptic climate change warnings can be counter-productive

by BPS Research Digest in BPS Research Digest

Many people believe implicitly that the world is fair, that bad things by and large don't happen to good people. When presented with evidence to the contrary, they ignore or downplay it. According to Matthew Feinberg and Robb Willer, this is exactly what happens when such people are presented with dire warnings about global warning.

Feinberg and Willer had 97 undergrads read one of two versions of a newspaper-style article about global warming and its likely consequences. Both articles began in........ Read more »

join us!

Do you write about peer-reviewed research in your blog? Use ResearchBlogging.org to make it easy for your readers — and others from around the world — to find your serious posts about academic research.

If you don't have a blog, you can still use our site to learn about fascinating developments in cutting-edge research from around the world.

Register Now

Research Blogging is powered by SMG Technology.

To learn more, visit seedmediagroup.com.