Post List

  • February 7, 2011
  • 05:47 AM

Following up on LOX

by Cancer Research UK in Cancer Research UK - Science Update

Around two years ago we wrote about research from scientists at the Institute of Cancer Research, partly funded by Cancer Research UK, who discovered that a molecule called LOX (lysyl oxidase) plays an important role in the spread of breast cancer around the body. Now the same team, led by Dr Janine Erler, has shown [...]... Read more »

Baker AM, Cox TR, Bird D, Lang G, Murray GI, Sun XF, Southall SM, Wilson JR, & Erler JT. (2011) The Role of Lysyl Oxidase in SRC-Dependent Proliferation and Metastasis of Colorectal Cancer. Journal of the National Cancer Institute. PMID: 21282564  

  • February 7, 2011
  • 05:40 AM

Reef Noise As Guide for Floating Crustaceans

by Sam in Oceanographer's Choice

Imagine, for a moment, that you are a small planktonic crustacean floating in the tropical ocean. Your world is vast, but its physical geography at your scale is relatively simple. Light and warmth are above, dark and cold are down. … Continue reading →... Read more »

Stephen D. Simpson, Andrew N. Radford, Edward J. Tickle, Mark G. Meekan, Andrew G. Jeffs. (2011) Adaptive Avoidance of Reef Noise. PLoS ONE. info:/doi:10.1371/journal.pone.0016625

  • February 7, 2011
  • 03:56 AM

Testing the Fountain of Youth in the lab

by Charles Daney in Science and Reason

It's been more than 10 years since it was noticed that certain enzymes – the sirtuins – had life-extending properties in organisms like yeast, and later nematodes, fruit flies, and mice. The excitement spread to other compounds, such as resveratrol, that seemed to activate or assist sirtuins. Hopes were high that such things might offer the known longevity benefits of calorie restriction in a pill form. Ever since then the gold rush has been on to figure out how these things work &nd........ Read more »

  • February 7, 2011
  • 01:53 AM

Facebook Use and Personality

by Dr Shock in Dr Shock MD PhD

Does using online social networking compensate for certain character traits? It’s suggested that participating in online social networks such as Facebook or twitter is mostly done by those who struggle to make social connections in face to face contacts. The use of Facebook to enhance their social relationships online. This is called the social compensation [...]

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  • February 7, 2011
  • 12:53 AM

Choosing chronic pain questionnaires

by Bronwyn Thompson in Healthskills: Skills for Healthy Living

Choosing a set of questionnaires for an assessment battery can be a task fraught with all kinds of traps, because if there is one thing bound to get clinical tongues flapping, it’s the idea that their favourite questionnaire will be left out of the mix! And to complicate matters for us Southern Hemispherians, most of … Read more... Read more »

DWORKIN, R., TURK, D., WYRWICH, K., BEATON, D., CLEELAND, C., FARRAR, J., HAYTHORNTHWAITE, J., JENSEN, M., KERNS, R., & ADER, D. (2008) Interpreting the Clinical Importance of Treatment Outcomes in Chronic Pain Clinical Trials: IMMPACT Recommendations. The Journal of Pain, 9(2), 105-121. DOI: 10.1016/j.jpain.2007.09.005  

  • February 6, 2011
  • 09:00 PM

Misrepresentation of ADHD in scientific journals and in the mass media

by Hadas Shema in Information Culture

The scientific community often discusses the misrepresentation of health news by the media. A less discussed subject is misrepresentation of data in the scientific literature. Gonon, Bezard and Boraud used their knowledge about ADHD to find misrepresentations of data in scientific literature and mass media, and found that the misrepresentation problem often begins in the scientific literature. 1. Internal inconsistenciesThe good news is that only 2 out of about 360 papers (Barbaresi et al and V........ Read more »

  • February 6, 2011
  • 08:11 PM

Deep-Sea Creatures Play in the Same Band

by Dr. M in Deep Sea News

I am really loving the new paper by O’Hara et al.  The gist is we typically think of the different oceans having unique sets of deep-sea organisms.  A Pacific set of animals, an Atlantic set, an Indian set and so on.  But O’Hara and colleagues show instead that brittle stars are differentiated along broad latitudinal bands.  This is very similar to . . . → Read More: Deep-Sea Creatures Play in the Same Band... Read more »

  • February 6, 2011
  • 08:09 PM

Childhood ADHD and Food "Sensitivity"

by William Yates, M.D. in Brain Posts

I admit that I am a skeptic about the effect of diet on ADHD and most mental disorders.  No one can argue that a healthy diet should not be routinely advised for all individuals with or without an emotional disorder.   However, I am open to looking at research studies and data--I'm willing to change my opinion if the research supports such a change.A group of Dutch researchers recently published a study of diet and ADHD symptoms in a small sample of children with ADHD be........ Read more »

  • February 6, 2011
  • 04:44 PM

On never forgetting where you came from: Epigenetic differences in iPSCs

by Joe Hanson in It's Okay To Be Smart

Recent high-impact papers have highlighted concerns about the epigenetic differences between reprogrammed pluripotent cells and their embryonic stem cell counterparts. However, when one considers the propagation of DNA methyl marks and the history of this young field, these observations are neither new or surprising. In fact, brand new research released this month indicates that their differences might not be as detrimental to therapeutic potential as once thought.... Read more »

Lister, R., Pelizzola, M., Kida, Y., Hawkins, R., Nery, J., Hon, G., Antosiewicz-Bourget, J., O’Malley, R., Castanon, R., Klugman, S.... (2011) Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells. Nature. DOI: 10.1038/nature09798  

Ptashne M. (2007) On the use of the word 'epigenetic'. Current biology : CB, 17(7). PMID: 17407749  

Polo JM, Liu S, Figueroa ME, Kulalert W, Eminli S, Tan KY, Apostolou E, Stadtfeld M, Li Y, Shioda T.... (2010) Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells. Nature biotechnology, 28(8), 848-55. PMID: 20644536  

Kim K, Doi A, Wen B, Ng K, Zhao R, Cahan P, Kim J, Aryee MJ, Ji H, Ehrlich LI.... (2010) Epigenetic memory in induced pluripotent stem cells. Nature, 467(7313), 285-90. PMID: 20644535  

  • February 6, 2011
  • 04:32 PM

Droughts and the decline and rise of urban civilizations

by Michael Smith in Wide Urban World

Paleoclimatic data from a new tree-ring sequence in central Mexico have implications for the fall and rise of cities and urban societies before the Spanish conquest.... Read more »

Stahle, David W., José Villanueva-Díaz, Dorian J. Burnette, Julián Cerano Paredes, Richard Heim, Jr., Falko K. Fye, Rodolfo A. Soto, Matthew D. Therrell, Malcolm K. Cleaveland, and D. K. Stahle. (2011) Major Mesoamerican Droughts of the Past Millennium. Geophysical Research Letters. info:/

  • February 6, 2011
  • 04:11 PM

It isn’t just students: Medical researchers aren’t citing previous work either

by bjms1002 in the Undergraduate Science Librarian

One of the things that faculty often complain about is that students don’t adequately track down and cite enough relevant material for their term papers and projects.  This problem isn’t confined to undergraduates.  A study in the January 4, 2011 issue of the Annals of Internal Medicine by Karen Robinson and Steven Goodman finds that [...]... Read more »

  • February 6, 2011
  • 03:56 PM

Should a disaster occur, do you know how your children would perceive it?

by Zijing He in ionpsych

As media technology advances, we not only gain more access to world news about all kinds of disasters; we also become more concerned about potential disasters that might happen to us or our loved ones, especially to our innocent children. … Continue reading →... Read more »

  • February 6, 2011
  • 03:26 PM

Does Parenting Matter?

by W.B. PsychCents in ionpsych

While at the grocery store, you may head down an aisle only to quickly turn around because you immediately feel uncomfortable when you overhear a parent who, with every scold, makes her child cry even harder about the chocolate bar … Continue reading →... Read more »

Bokhorst, C., Bakermans-kranenburg, M., Pasco fearon, R., Van ijzendoorn, M., Fonagy, P., & Schuengel, C. (2003) The Importance of Shared Environment in Mother-Infant Attachment Security: A Behavioral Genetic Study. Child Development, 74(6), 1769-1782. DOI: 10.1046/j.1467-8624.2003.00637.x  

Sroufe, L.A., Egeland, B., Carlson, E.A., . (2005) The development of the person: The Minnesota study of risk and adaptation from birth to adulthood. . New York: Guilford. info:/

  • February 6, 2011
  • 01:35 PM

Study: When Your Super Bowl Team Goes Down, Your Death Risk Goes Up

by David Berreby in Mind Matters

The link between Super Bowls and heart failure is usually written in guacamole and beer. But we are a social species, whose feelings about group identity have a direct impact on health, via the brain-body connection. Hence this study in this month's Clinical Cardiology, which says death rates in ...Read More
... Read more »

  • February 6, 2011
  • 12:17 PM

What Stem Cells Need to Survive in the Brain

by Shaheen Lakhan in Brain Blogger

Stem cells have been a hot and also controversial topic in research and in the media for the last few years, as they might be used in the future to repair injured tissue in such diverse disease like heart attacks, strokes, Alzheimer’s disease, Parkinson’s disease and many more. But, there are also unsolved ethical issues [...]... Read more »

  • February 6, 2011
  • 10:33 AM

Ultra-tough glass: bending without breaking

by Anna Goldstein in Berkeley Science Review Blog

Many years ago, my parents and brother were driving home late at night, full speed on a highway, when a large rock thrown off an overpass struck their car's windshield. There was a time when an impact like that would have shattered the windshield glass, likely leading to a tragic accident and - for me - a painful childhood. But, thanks to the modern miracle of laminated safety glass, the windshield did not shatter; it only cracked. The rock rolled away, my dad maintained control of the car, and ........ Read more »

Demetriou MD, Launey ME, Garrett G, Schramm JP, Hofmann DC, Johnson WL, & Ritchie RO. (2011) A damage-tolerant glass. Nature materials, 10(2), 123-8. PMID: 21217693  

  • February 6, 2011
  • 10:31 AM

RNA is so passé. Mitochondrial ribosomes ditch rRNA in favour of protein

by Gemma Atkinson in Protein evolution and other musings

Mitochondria are the energy-producing organelles of eukaryotes that evolved from a endosymbiotic bacterial ancestor, probably before the divergence of all known eukaryotes. They retain a minimal genome, which in humans amounts to just 37 genes: 13 for components of respiratory complexes and 24 for translation (22 transfer (t) RNAs and 2 ribosomal (r) RNAs).Translation is pretty bizarre in mitochondria, and very different among different eukaryotic lineages in terms of mRNA features and involveme........ Read more »

  • February 6, 2011
  • 10:28 AM

How “wild” is Ethiopian forest coffee?

by Julie Craves in Coffee & Conservation

Ethiopia is the birthplace of coffee.  Coffea arabica originates in and still grows wild in Ethiopia in areas which are included in the Eastern Afromontane Biodiversity hotspot.  This hotspot — [...]

... Read more »

  • February 6, 2011
  • 08:59 AM

Deep Sea 101: Lessons from the Census of Marine Life

by Kevin Zelnio in Deep Sea News

←Previous lesson: Introduction and What Is the Deep Sea?
Click image to go to Census of Marine Life!
Last week we kicked off our online class with an introduction to the deep sea environment. Before we continue on to spend a bit of time talking about the history of deep-sea exploration, I want to discuss the current state . . . → Read More: Deep Sea 101: Lessons from the Census of Marine Life... Read more »

Costa, D., Huckstadt, L., Crocker, D., McDonald, B., Goebel, M., & Fedak, M. (2010) Approaches to Studying Climatic Change and its Role on the Habitat Selection of Antarctic Pinnipeds. Integrative and Comparative Biology, 50(6), 1018-1030. DOI: 10.1093/icb/icq054  

  • February 6, 2011
  • 08:50 AM

random chance vs determinism | Knowing, Part 1

by Michael Lombardi in a New Life in the Sea

This post is a continuation of the analysis of my marathon movie weekend. As I escaped the creepiness, yet remained perplexed by The Fourth Kind, I found myself more deeply enveloped by 'Knowing'. The film followed my alien themed movie marathon, but more subtly, and emphasized a focus on our perceptions of reality.

In the early part of the film, we meet Nicholas Cage's character, a professor from MIT, who poses a challenge to his students to consider whether life is the product........ Read more »

unknown. (1932) Determinism Defined. Nature, 129(3250), 228-228. DOI: 10.1038/129228d0  

Kampen, N. (1991) Determinism and predictability. Synthese, 89(2), 273-281. DOI: 10.1007/BF00413908  

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