Post List

  • February 16, 2011
  • 06:00 AM

Trick of the Trade: Serial lactate measurements in sepsis?

by Michelle Lin in Academic Life In Emergency Medicine

Does your Emergency Department have computerized spectrophotometric catheters to measure continuous central venous oxygen saturation (ScvO2) in early goal directed therapy (EGDT) for severe sepsis? That's what was used in the original Rivers' EGDT study.I've never even seen one before.Many emergency physicians are getting around not having the specialized equipment issue by obtaining intermittent venous blood gas measurements off of a central venous line.But what if you had a 30 y/o wo........ Read more »

Jones AE, Shapiro NI, Trzeciak S, Arnold RC, Claremont HA, Kline JA, & Emergency Medicine Shock Research Network (EMShockNet) Investigators. (2010) Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial. JAMA : the journal of the American Medical Association, 303(8), 739-46. PMID: 20179283  

  • February 16, 2011
  • 05:42 AM

Mitigation or Contingency Strategies against Disruptions

by Daniel Dumke in SCRM Blog - Supply Chain Risk Management

Uncertainty can be categorized in continuous risk, more slowly changing patterns, and disruptions, which describe abrupt changes in a system.
Tomlin (2006) investigates the question which supply chain strategies perform best when dealing with the later.

Mitigation vs. Contingency Planning
From case studies analyzed in literature the author first deducts disruption management strategies used in practices. The summary can be seen in figure 1.
Figure 1: Strategies for Managing Disruptions (T........ Read more »

  • February 16, 2011
  • 05:30 AM

Think the gym's gonna make you slim? Think again.

by Yoni Freedhoff in Weighty Matters

Not sure why we're still funding exercise for weight loss studies as two recent comprehensive reviews of the medical literature have concluded that weight loss by means of exclusively exercise interventions run in the order of a 1-3% loss in response to 180 mins/wk of exercise and no loss at all if less than 150 mins/wk, but yet here's another one to discuss.What's a bit different about this study is that it was long - 18 months and hence perhaps will yield a different outcome.So what'd the stud........ Read more »

Jakicic, J., Otto, A., Lang, W., Semler, L., Winters, C., Polzien, K., & Mohr, K. (2010) The Effect of Physical Activity on 18-Month Weight Change in Overweight Adults. Obesity, 19(1), 100-109. DOI: 10.1038/oby.2010.122  

  • February 16, 2011
  • 04:48 AM

Milgram's obedience studies - not about obedience after all?

by BPS Research Digest in BPS Research Digest

Stanley Milgram's seminal experiments in the 1960s may not have been a demonstration of obedience to authority after all, a new study claims.

Milgram appalled the world when he showed the willingness of ordinary people to administer a lethal electric shock to an innocent person, simply because an experimenter ordered them to do so. Participants believed they were punishing an unsuccessful 'learner' in a learning task; the reality was the learner was a stooge. The conventional view is that the ........ Read more »

  • February 16, 2011
  • 02:00 AM

Advocating health programs through social media

by SAGE Insight in SAGE Insight

Advocacy 2.0: Advocating in the Digital Age From Health Promotion Practice To improve health, we must continue to engage in advocacy for people, programs, policies, and the profession.  Economic difficulties and competitive interests leave health education programs in a vulnerable position. More and more, professional organizations embrace advocacy as a significant component within their organizations. [...]... Read more »

Galer-Unti, R. (2010) Advocacy 2.0: Advocating in the Digital Age. Health Promotion Practice, 11(6), 784-787. DOI: 10.1177/1524839910386952  

  • February 16, 2011
  • 01:50 AM

The power of learning a second language: look to the caudate

by Scicurious in Neurotic Physiology

Sci’s terrible at languages. TERRIBLE. In my time, I’ve successfully mastered English, and attempted to master four other languages (five if you count a brief foray into Elvish when I was 15, but that doesn’t really count) in my time. I have failed at ALL of them. Every once in a while I would achieve [...]... Read more »

Tan LH, Chen L, Yip V, Chan AH, Yang J, Gao JH, & Siok WT. (2011) Activity levels in the left hemisphere caudate-fusiform circuit predict how well a second language will be learned. Proceedings of the National Academy of Sciences of the United States of America, 108(6), 2540-4. PMID: 21262807  

  • February 16, 2011
  • 01:29 AM

Sustainability and the triple bottom line

by Jan Husdal in

Sustainability has become a huge buzzword, both in today's business world and within the broader facets of society. Sustainability has evolved from a perspective and investigation of standalone research in social and environmental areas, through a corporate social responsibility perspective, and towards a convergence of perspectives of sustainability as the triple bottom line. [ ... ]... Read more »

Carter, C., & Easton, P. (2011) Sustainable supply chain management: evolution and future directions. International Journal of Physical Distribution , 41(1), 46-62. DOI: 10.1108/09600031111101420  

  • February 15, 2011
  • 10:24 PM


by Jon Wilkins in Lost in Transcription


Snowflakes by jonfwilkins
For sketches of the 80 different snowflake types, see the referenced paper, which presents them taxonomically, or check out the key figures here and here.

Magono, C., & Lee, C. W. (1966). Meteorological Classification of Natural Snow Crystals Journal of the Faculty of Science, Hokkaido University, Japan, Ser. VII, 2 (4), 321-335

... Read more »

Magono, C., & Lee, C. W. (1966) Meteorological Classification of Natural Snow Crystals. Journal of the Faculty of Science, Hokkaido University, Japan, Ser. VII, 2(4), 321-335. info:other/

  • February 15, 2011
  • 10:07 PM

Why Do Early Experiences Continue to Influece Our Relationships?

by W.B. PsychCents in ionpsych

How often do you think about your early experiences with your parents? Perhaps you’re thinking: not all that often. Although you might not think about those formative years, they continue to influence you even in adulthood. Research suggest that your … Continue reading →... Read more »

  • February 15, 2011
  • 09:45 PM

Revival of the cell phone vs. the brain?

by Casey Rentz in Natural Selections

I don't want to hear it again--cell phone waves are harmful to your brain...stick your face close enough for long enough and you'll turn to mush. But, there's a new paper out there that I'm afraid might catch on as fodder for the pseudoscience susceptible.[Just cool animation. Not part of the study.]Scientists at Caltech recently found that weak electrical fields in the brain might cause neurons to fire in sync. It's really kinda neat. Researchers dropped a cluster of minuscule electrodes into a........ Read more »

Anastassiou CA, Perin R, Markram H, & Koch C. (2011) Ephaptic coupling of cortical neurons. Nature neuroscience, 14(2), 217-23. PMID: 21240273  

  • February 15, 2011
  • 08:31 PM

Deep sea carbon cycling: microbial action, and mystery

by Kevin Bonham in Food Matters

How excited was I to learn that the most recent issue of Nature Geoscience had a special focus on deep sea carbon cycling? I admit it, pretty excited. I was even more excited to learn that one of the 3 papers making up this special focus was about the microbial component of deep sea carbon cycling. This may not be something that you think about every day, but I do... well most days at least. The first two sentences of this paper explain why I find this topic so interesting.

Circulation of........ Read more »

  • February 15, 2011
  • 07:47 PM

Are You Normal? It Depends.

by Jenika in ionpsych

We all have personality quirks.  But occasionally, a person may behave so eccentrically and erratically that they cannot function in regular life situations.  It might seem easy to identify a person who behaves oddly.  They might be chronically suspicious of … Continue reading →... Read more »

Dickey CC, Morocz IA, Minney D, Niznikiewicz MA, Voglmaier MM, Panych LP, Khan U, Zacks R, Terry DP, Shenton ME.... (2010) Factors in sensory processing of prosody in schizotypal personality disorder: an fMRI experiment. Schizophrenia research, 121(1-3), 75-89. PMID: 20362418  

Guitart-Masip M, Pascual JC, Carmona S, Hoekzema E, Bergé D, Pérez V, Soler J, Soliva JC, Rovira M, Bulbena A.... (2009) Neural correlates of impaired emotional discrimination in borderline personality disorder: an fMRI study. Progress in neuro-psychopharmacology , 33(8), 1537-45. PMID: 19748540  

  • February 15, 2011
  • 06:58 PM

Going upstream in the scientific process, literally.

by Brian Mossop in The Decision Tree

My latest post for Wired Playbook reports on a new idea that two UK researchers have proposed for keeping tabs on which Olympic athletes are using performance-enhancing drugs. Rather than having the athletes pee in a cup or get blood drawn just before competition, the researchers believe that searching for drug metabolites in the wastewater [...]... Read more »

  • February 15, 2011
  • 05:46 PM

The Grand Challenge of Aerosolised Vaccines

by Connor Bamford in The Rule of 6ix

Despite the development of effective vaccines, many human populations are currently at the mercy of numerous endemic viral pathogens. Measles virus is one such pathogen that, in 2008, was responsible for 164,000 deaths; the worst effected areas are South-East Asia and Africa (WHO stats can be found here). You might find this surprising as there is currently a very good measles vaccine in use – in fact you probably received at some point during childhood and are protected from future in........ Read more »

Lin, W., Griffin, D., Rota, P., Papania, M., Cape, S., Bennett, D., Quinn, B., Sievers, R., Shermer, C., Powell, K.... (2011) Successful respiratory immunization with dry powder live-attenuated measles virus vaccine in rhesus macaques. Proceedings of the National Academy of Sciences. DOI: 10.1073/pnas.1017334108  

  • February 15, 2011
  • 04:58 PM

Cannabis Use and Psychosis (Part 2)

by William Yates, M.D. in Brain Posts

I reviewed a research study last fall examining a Dutch study of cannabis use and psychotic symptoms.  That post is linked here.  In summary, the study suggested cannabis probably does not produce psychotic symptoms in the majority of users.  However, if you have a family member with a psychotic disorder (suggesting you may have a genetic risk for psychosis) you may be more likely to experience psychotic symptoms (i.e. hallucinations/delusions) with cannabis use.  This risk m........ Read more »

  • February 15, 2011
  • 03:54 PM

Fishy Business: Omega-3 Supplements

by Richard Masters in Elements Science

Richard Masters delves into the world of Omega 3 supplements which are conquering the world of nutrition and finds the evidence far from conclusive.

Related posts:Fish oil “not useful” in treatment of Alzheimer’s Disease
Hold homeopaths to account
Health round up
... Read more »

Lespérance, F., Frasure-Smith, N., St-André, E., Turecki, G., Lespérance, P., & Wisniewski, S. (2010) The Efficacy of Omega-3 Supplementation for Major Depression. The Journal of Clinical Psychiatry. DOI: 10.4088/JCP.10m05966blu  

  • February 15, 2011
  • 03:08 PM

State of the Field: Satellite tagging sharks

by WhySharksMatter in Southern Fried Science

Modern shark researchers have access to a variety of high-tech tools. Acoustic tags with noises specific to each individual shark signal a receiver (or network of receivers) every time the shark passes nearby. Some tags have three-dimensional accelerometers, allowing researchers to study the small scale movement patterns and behaviors of sharks. Others, which [...]... Read more »

  • February 15, 2011
  • 01:39 PM

Canada Releases World’s First Evidence-Based Sedentary Guidelines

by Travis Saunders, MSc, CEP in Obesity Panacea

Exciting news today – this morning the Canadian Society for Exercise Physiology (CSEP) released the world’s first evidence-based sedentary behaviour guidelines.  There have been some guidelines in the past, most notably for screen time, but they were essentially based on best-guesses more than any objective evidence.
These new guidelines are specifically for those aged 5-17, although there will hopefully be guidelines for both older and younger age-groups in the near ........ Read more »

Tremblay, MS, Leblanc, AG, Janssen, I, Kho, ME, Hicks, A, Murumets, K, Colley, RC, & Duggan, M. (2011) Canadian Sedentary Behaviour Guidelines for Children and Youth. Applied Physiology, Nutrition and Metabolism. info:/10.1139/H11-012

  • February 15, 2011
  • 01:12 PM

Lying moths use the threat of getting eaten to help their sex lives

by Matt Soniak in

It’s a love story as old as time itself: boy Asian corn borer moth (Ostrinia furnacalis) meets girl Asian corn borer moth; girl secretes sex pheromones; boy goes through his courtship ritual, a little song-and-dance routine where he rubs his wings against his thorax to produce a soft, whispering sound. It’s a sweet little love [...]... Read more »

  • February 15, 2011
  • 01:09 PM

Humans draw the LINE at Gonorrhea. Not that it helps.

by Iddo Friedberg in Byte Size Biology

The day after Valentine’s Day. Ah! What better day in the year can we find to discuss gonorrhea? In the US alone 700,000 people are infected each year, and 5 million are infected worldwide. In most infected men gonorrhea causes urethral discharge and pain while urinating. The reason is that Neisseria gonhorrea have little hair-like structures called fimbriae. This makes them very sticky and they stick to the urethra’s walls. Then you get inflammation, urethritis and urinatio........ Read more »

Mark T. Anderson, & H. Steven Seifert. (2011) Opportunity and Means: Horizontal Gene Transfer from the Human Host to a Bacterial Pathogen. mBio, 1-4. info:/10.1128/​mBio.00005-11

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