Accurate species distribution data is necessary to address biodiversity challenges. To save endangered species, conservationists need to know which species populations are contracting or expanding. Restoring an ecosystem requires an accurate picture of how the ecosystem existed historically. Unfortunately, existing global data collections such as the Global Biodiversity Information Facility and IUCN Red List underrepresent some geographic areas, especially in the tropics, and may not show accura........ Read more »
Boakes, E., McGowan, P., Fuller, R., Chang-qing, D., Clark, N., O'Connor, K., & Mace, G. (2010) Distorted Views of Biodiversity: Spatial and Temporal Bias in Species Occurrence Data. PLoS Biology, 8(6). DOI: 10.1371/journal.pbio.1000385
A lot of nutritional studies, especially epidemiological, rely on certain biomarkers to assess disease risk upon interventions. Many of these biomarkers are accepted with little challenge, and thus become very common to examine. Historically, jumping too quickly to conclusions from associations has confined our nation to a nutritional nut-house; people are confused because of mixed [...]... Read more »
Vergeer M, Holleboom AG, Kastelein JJ, & Kuivenhoven JA. (2010) The HDL hypothesis - Does high-density lipoprotein protect from atherosclerosis?. Journal of lipid research. PMID: 20371550
Born between 1982 and 1993, the kids of the Baby Boomers are sometimes also referred to as the Millennial generation, Generation Y, Net Generation, or Echo-Boomers.
This generation has fully embraced social networking (e.g. Facebook) and file sharing (e.g. Napster) and spends an average of 3.5 hours a day online. They have also been noted to [...]... Read more »
Barkin SL, Heerman WJ, Warren MD, & Rennhoff C. (2010) Millennials and the World of Work: The Impact of Obesity on Health and Productivity. Journal of business and psychology, 25(2), 239-245. PMID: 20502510
Pneumonia is the leading cause of childhood death in sub-Saharan Africa and while it is well known that many pneumonias are caused by bacteria such as Streptococcus pneumonia – for which vaccines are available – we know less about those caused by viruses. A new study, published in the Journal of the American Medical Association [...]... Read more »
Berkley, J., Munywoki, P., Ngama, M., Kazungu, S., Abwao, J., Bett, A., Lassauniere, R., Kresfelder, T., Cane, P., Venter, M.... (2010) Viral Etiology of Severe Pneumonia Among Kenyan Infants and Children. JAMA: The Journal of the American Medical Association, 303(20), 2051-2057. DOI: 10.1001/jama.2010.675
One of the most significant papers ever published in the annals of science appeared recently; it deals, for the first time ever, with one of the biggest scientific questions ever faced by the scientific community, and uses cutting-edge technology and awesome powers of deductive reasoning and logic to reach shocking, paradigm-shifting conclusions. I refer, of course, to Don Henderson and Darren Naish's Journal of Theoretical Biology article 'Predicting the buoyancy, equilibrium and potential ........ Read more »
Henderson DM, & Naish D. (2010) Predicting the buoyancy, equilibrium and potential swimming ability of giraffes by computational analysis. Journal of theoretical biology. PMID: 20385144
We're defined in part by where we are, the places we go and what we do there. We adorn our homes with paraphernalia caught in the net of life - the photos, the books and pictures. But what happens when you're homeless? How do you define your space and identity when your home is a public place? To find out, Darrin Hodgetts and colleagues have conducted an unusual 'ethnographic' case study with 'Brett', a 44-year-old homeless man in Auckland.The researchers gave Brett a camera, asked him to take p........ Read more »
Hodgetts D, Stolte O, Chamberlain K, Radley A, Groot S, & Nikora LW. (2009) The mobile hermit and the city: Considering links between places, objects, and identities in social psychological research on homelessness. The British journal of social psychology / the British Psychological Society. PMID: 19531282
This is another post in Sci's investigation into the current studies being performed on eating disorders, particularly binge eating and bulimia. Usually I try to focus on the dysregulation of reward-related systems in these disorders, but this paper will be a little different.
Faris et al. "De-Stabilization of the Positive Vago-Vagal Reflex in Bulimia Nervosa" Physiology and Behavior, 2008.
It's kind of in the nature of an eating disorder that there aren't any really funny pictures or someth........ Read more »
FARIS, P., HOFBAUER, R., DAUGHTERS, R., VANDENLANGENBERG, E., IVERSEN, L., GOODALE, R., MAXWELL, R., ECKERT, E., & HARTMAN, B. (2008) De-stabilization of the positive vago-vagal reflex in bulimia nervosa. Physiology , 94(1), 136-153. DOI: 10.1016/j.physbeh.2007.11.036
Richter DC, Ott F, Auch AF, Schmid R, & Huson DH (2008). MetaSim: a sequencing simulator for genomics and metagenomics. PloS one, 3 (10) PMID: 18841204An article from the Huson's Group at Tübingen University has just came out in the Open Access (and scientific publishing innovator) journal PLoS ONE, describing MetaSim, a software to produce artificial or syntetic or in silico metagenomes out of a selection of completely sequenced genomes.This is just "heaven-sent" for me since I've been wor........ Read more »
Richter DC, Ott F, Auch AF, Schmid R, & Huson DH. (2008) MetaSim: a sequencing simulator for genomics and metagenomics. PloS one, 3(10). PMID: 18841204
Mavromatis K, Ivanova N, Barry K, Shapiro H, Goltsman E, McHardy AC, Rigoutsos I, Salamov A, Korzeniewski F, Land M.... (2007) Use of simulated data sets to evaluate the fidelity of metagenomic processing methods. Nature methods, 4(6), 495-500. PMID: 17468765
A masterpiece of science blogging was posted here (http://suicyte.wordpress.com/2007/11/20/smallest-primate-ever-discovered/), addressing the finding of primate sequences in the GOS dataset, just one of the unassesed ambiguities in metagenomics.The post is beautifully written and made me laugh really loud. The point is that metagenomics is sometimes being overselled just in the very same way as genomics has been (see Eisen's blog for just some examples) and this leads to an skeptic counterwave........ Read more »
Rusch DB, Halpern AL, Sutton G, Heidelberg KB, Williamson S, Yooseph S, Wu D, Eisen JA, Hoffman JM, Remington K.... (2007) The Sorcerer II Global Ocean Sampling expedition: northwest Atlantic through eastern tropical Pacific. PLoS biology, 5(3). PMID: 17355176
I try to buy organic fruits and veggies, at least the dirty dozen. Organic milk too. Pasta, once or twice. Pajamas, never. So you may not be surprised to learn I read the new study linking ADHD to pesticides as my children gobbled up grapes that were not organic, this being New Jersey and not the West Coast where I imagine pesticide-free is an achievable if not cost-effect lifestyle. After finishing the article published in the curre........ Read more »
Bouchard, M., Bellinger, D., Wright, R., & Weisskopf, M. (2010) Attention-Deficit/Hyperactivity Disorder and Urinary Metabolites of Organophosphate Pesticides. PEDIATRICS, 125(6). DOI: 10.1542/peds.2009-3058
Among the numerous and still informative ecological predictions made by Darwin, one posits that when species are introduced into regions where they were not formerly found, the most successful tend to not have close relatives already occupying the region. This is known as Darwin's Naturalization Hypothesis, and his logic was that among close relatives, where ecological requirements should be most similar, the struggle for existence is most severe. Thus the modern formulation is that invader succ........ Read more »
Jiang, L., Tan, J., & Pu, Z. (2010) An Experimental Test of Darwin’s Naturalization Hypothesis. The American Naturalist, 175(4), 415-423. DOI: 10.1086/650720
A couple present to the ED with vomiting and paraesthesiae after eating at a seafood restaurant. Can you help them by solving the seafood poisoning conundrum?... Read more »
Friedman MA, & et al. (2008) Ciguatera fish poisoning: treatment, prevention and management. Marine Drugs, 6(3), 456-79. PMID: 19005579
While on the road here in San Francisco at the American Urology Association, I received an email from someone about latest news surrounding the breast cancer vaccine published in Nature Medicine. Expecting to find some snippets on how this vaccine...... Read more »
Jaini, R., Kesaraju, P., Johnson, J., Altuntas, C., Jane-wit, D., & Tuohy, V. (2010) An autoimmune-mediated strategy for prophylactic breast cancer vaccination. Nature Medicine. DOI: 10.1038/nm.2161
The bulk of research done on the evolution of sociality has focused on sexual pairings (aka interactions between males and females). While such interactions directly affect the reproductive success of the individuals involved, they are certainly not the only kind of interaction that matters. Female alliances have been shown to increase infant survival in a [...]... Read more »
Ramp, C., Hagen, W., Palsbøll, P., Bérubé, M., & Sears, R. (2010) Age-related multi-year associations in female humpback whales (Megaptera novaeangliae). Behavioral Ecology and Sociobiology. DOI: 10.1007/s00265-010-0970-8
Cooperation Between Translating Ribosomes and RNA Polymerase in Transcription Elongation Sergey Proshkin, A. Rachid Rahmouni, Alexander Mironov, Evgeny Nudler Science, Vol. 328. no. 5977: pp. 504 – 508, 23 April 2010. DOI: 10.1126/science.1184939 This week’s smart summary and analysis by Pavan Vaidyanathan: In this paper, the authors propose a mechanism for active physical cooperation between [...]... Read more »
Proshkin S, Rahmouni AR, Mironov A, & Nudler E. (2010) Cooperation between translating ribosomes and RNA polymerase in transcription elongation. Science, 328(5977), 504-8. PMID: 20413502
Over the last week or so, we’ve received a lot of enquiries to our helpline and email service about a new experimental cancer drug called reolysin. This followed several reports in the national press the week previously. Reolysin is a relatively new drug developed from a fairly harmless type of virus called a reovirus. Most [...]... Read more »
Harrington, K., Karapanagiotou, E., Roulstone, V., Twigger, K., White, C., Vidal, L., Beirne, D., Prestwich, R., Newbold, K., Ahmed, M.... (2010) Two-Stage Phase I Dose-Escalation Study of Intratumoral Reovirus Type 3 Dearing and Palliative Radiotherapy in Patients with Advanced Cancers. Clinical Cancer Research, 16(11), 3067-3077. DOI: 10.1158/1078-0432.CCR-10-0054
While attending last year’s American Elasmobranch Society conference, I was asked to fill out a survey concerning my views on lethal shark research. My response, along with those of many other participants, has now been analyzed and written up into a new essay in the Journal of Conservation Biology. Michelle Heupel and Colin Simpendorfer argue [...]... Read more »
HEUPEL, M., & SIMPFENDORFER, C. (2010) Science or Slaughter: Need for Lethal Sampling of Sharks. Conservation Biology. DOI: 10.1111/j.1523-1739.2010.01491.x
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I recently came across this post by Michelle Dawson that states the thesis that one of the abnormalities in Autism spectrum disorders is due to abnormal circadian clock functioning. More specifically, the clock is internally driven and has a greeter ‘free running’ period and does not entrain readily to environmental and social clues.
Autistics More >Rating: 0.0/10 (0 votes cast)
Related posts:Tick, Tick, Tock: The Mouse without the C........ Read more »
Barnard, A., & Nolan, P. (2008) When Clocks Go Bad: Neurobehavioural Consequences of Disrupted Circadian Timing. PLoS Genetics, 4(5). DOI: 10.1371/journal.pgen.1000040
Prozac and suicide: what's going on?Many people think that SSRI antidepressants do indeed cause suicide, and in recent years this idea has gained a huge amount of attention. My opinion is that, well, it's all rather complicated...At first glance, it seems as though it should be easy to discover the truth. SSRIs are some of the most studied drugs in the world. We have data from several hundred randomized placebo-controlled trials, totaling tens of thousands of patients. Let's just look and see wh........ Read more »
Dudley, M., Goldney, R., & Hadzi-Pavlovic, D. (2010) Are adolescents dying by suicide taking SSRI antidepressants? A review of observational studies. Australasian Psychiatry, 18(3), 242-245. DOI: 10.3109/10398561003681319
In every environment there will be competition for resources, and there are generally two ways organisms deal with this; generalise or specialise. To generalise, you try to cope with as many different conditions as possible, so that if you get out-competed in one area you can try to cope with the conditions elsewhere. To specialise, you get damn good at using the conditions in your little niche, in the hope that you'll be better than anyone else who comes along, and be able to out-compete them.T........ Read more »
Rocap G, Larimer FW, Lamerdin J, Malfatti S, Chain P, Ahlgren NA, Arellano A, Coleman M, Hauser L, Hess WR.... (2003) Genome divergence in two Prochlorococcus ecotypes reflects oceanic niche differentiation. Nature, 424(6952), 1042-7. PMID: 12917642
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