Post List

  • November 29, 2010
  • 01:31 PM

How to transfer research into practice – more questions than answers

by Bronwyn Thompson in Healthskills: Skills for Healthy Living

With a background in a health profession not known for its love of science, I suppose when I came across evidence based health care I felt a strong sense of relief. Here, at last, was a way to work out what to do when faced with the task of helping people with pain.  I was … Read more... Read more »

  • November 29, 2010
  • 01:29 PM

Life in the moment is happier but less imaginative. Just ask your iphone.

by Caspar Addyman in Your Brain on Drugs

This Science Brevia article is the first published example I’ve seen using smartphone technologies to collect psychological data. It comes from Dan Gilbert’s ever inventive lab. They used an iphone application to run an experience sampling study. The article is so short that I can give you the whole abstract right now.... Read more »

Killingsworth, M., & Gilbert, D. (2010) A Wandering Mind Is an Unhappy Mind. Science, 330(6006), 932-932. DOI: 10.1126/science.1192439  

  • November 29, 2010
  • 12:00 PM

Climate change and digital music

by sciencebase in Sciencebase Science Blog

Information technology has a carbon footprint, that’s beyond doubt. Now, writing in a special issue of the Journal of Industrial Ecology, Christopher Weber, Jonathan Koomey and Scott Matthews in the US in work supported by grants from Microsoft Corporation and Intel Corporation have calculated that purchasing music digitally reduces the energy and carbon dioxide emissions [...]Climate change and digital music is a post from: Sciencebase Science Blog
... Read more »

  • November 29, 2010
  • 12:00 PM

Microbial Matchmakers

by Merry Youle in Small Things Considered

Back in 1983, researchers at Yale borrowed a microbiological tactic to study evolution at a "single gene locus" in a multicellular animal—the use of altered growth media to select for nutritional mutants. They confronted populations of Drosophila pseudoobscura with a growth medium containing either maltose or starch as the sole carbohydrate source and observed inherited changes to the α-amylase allozyme frequencies and the enzyme's location within the gut in the "starch flies." Interesting, u........ Read more »

Sharon G, Segal D, Ringo JM, Hefetz A, Zilber-Rosenberg I, & Rosenberg E. (2010) Commensal bacteria play a role in mating preference of Drosophila melanogaster. Proceedings of the National Academy of Sciences of the United States of America. PMID: 21041648  

  • November 29, 2010
  • 11:53 AM

New Insights into Scar Prevention

by Sanford- Burnham in Beaker

Bike accidents, C-sections and battlefield wounds can all leave scars. But those are only the scars you can see. Any tissue can scar (not just skin), making scar tissue more than a cosmetic problem. Heart muscle, for example, can scar after a heart attack, and the lungs, kidneys, the liver, and many other tissues can [...]... Read more »

Jarvinen TAH, & Ruoslahti E. (2010) Target-seeking anti-fibrotic compound enhances wound healing and suppresses scar formation in mice. Proceedings of the National Academy of Sciences. info:/

  • November 29, 2010
  • 11:29 AM

CBT for Irritable Bowel Syndrome

by William Yates, M.D. in Brain Posts

Irritable bowel syndrome (IBS) is a common functional gastrointestinal syndrome characterized by abdominal pain and bowel disturbances (diarrhea and/or constipation).  It is estimated to affect 10 to 20% of the population and treatment approaches are often unsatisfactory.  Irritable bowel syndrome can be viewed as a neuroscience problem from several perspectives.  Abnormal gastrointestinal motility and hypersensitivity has been identified in IBS--these functions are related to gut........ Read more »

  • November 29, 2010
  • 11:21 AM

What’s new in Biosimilars?

by Sally Church in Pharma Strategy Blog

Biosimilars are very much a hot topic of late.  They are approved new versions of innovator biopharmaceutical products, following patent expiry.  Essentially, this is like a generic version of the biologic product, hence their alternative name, follow-on biologics. Recently, the … Continue reading →... Read more »

Bosques, C., Collins, B., Meador, J., Sarvaiya, H., Murphy, J., DelloRusso, G., Bulik, D., Hsu, I., Washburn, N., Sipsey, S.... (2010) Chinese hamster ovary cells can produce galactose-α-1,3-galactose antigens on proteins. Nature Biotechnology, 28(11), 1153-1156. DOI: 10.1038/nbt1110-1153  

  • November 29, 2010
  • 11:05 AM

Does a White Nose Belie a Wing Load of Problems? More on WNS

by Michele in Promega Connections

In a recent post, I wrote about White-Nose Syndrome (WNS) in hibernating bats in North America. WNS was first documented on February 2006, by a recreational caver exploring Howes Cave in New York, who photographed a bat with an unusual white growth on its muzzle. In the few years since that picture was snapped, hundreds [...]... Read more »

  • November 29, 2010
  • 10:47 AM

Genetic modification of insects as pest control part 2

by Joe Ballenger in Biofortified

In part 1 of this series, I discussed the history of genetic modification in insects as pest control. We’ve been creating insect GMOs for the purposes of controlling pests for awhile. If you bombard insects with radiation, it can kill rapidly reproducing cells. High doses of radiation can also damage the DNA in quickly reproducing gamete producing cells to the point where it can’t be read, creating severe mutations that stop important proteins from Continue reading...... Read more »

Gong, P., Epton, M., Fu, G., Scaife, S., Hiscox, A., Condon, K., Condon, G., Morrison, N., Kelly, D., Dafa'alla, T.... (2005) A dominant lethal genetic system for autocidal control of the Mediterranean fruitfly. Nature Biotechnology, 23(4), 453-456. DOI: 10.1038/nbt1071  

  • November 29, 2010
  • 10:00 AM

Profiling Cheaters in College

by Richard Landers in NeoAcademic

Cheaters can be identified by their scores on the Dark Triad: narcissism, Machiavellianism, and psychopathy. But now that we can profile them, what comes next?... Read more »

  • November 29, 2010
  • 09:51 AM

how to navigate in deep space with dead stars

by Greg Fish in weird things

Not only are GPS devices useful, they’re also an ongoing experiment that keeps confirming special relativity’s spot on descriptions of how time flows for fast-moving objects. Without constant adjustments, GPS would be quickly rendered unusable because accurate timing of the signals being sent between the satellites and the moving object they’re supposed to track is [...]... Read more »

Angelo Tartaglia, Matteo Luca Ruggiero, & Emiliano Capolongo. (2010) A null frame for spacetime positioning by means of pulsating sources. Advances in Space Research. arXiv: 1001.1068v3

  • November 29, 2010
  • 09:48 AM

Level of Detail in a Simulation Model

by Daniel Dumke in SCRM Blog - Supply Chain Risk Management

After the last more general entries on managers perception of risk and measuring SC performance I wanted to make a detour back to the basics.
Simulation is one of the tools, which can be used for analyzing supply chain dynamics, optimization and to support corporate decision making.
One major question when starting a supply chain model has always been what level of detail should you choose? Someone could start with a single worker in an agent based simulation model and continue with the mac........ Read more »

  • November 29, 2010
  • 08:00 AM

How Obesity Promotes Breast Cancer

by Arya M. Sharma in Dr. Sharma's Obesity Notes

Regular readers of these pages are probably well aware of the increasing data on the importance of obesity as a risk factor for cancers.
This is particularly true for hormone-sensitive cancers like post-menopausal breast and ovarian cancer, which are significantly more common in women with excess weight. In addition, excess weight appears to negatively affect the [...]... Read more »

Di LJ, Fernandez AG, De Siervi A, Longo DL, & Gardner K. (2010) Transcriptional regulation of BRCA1 expression by a metabolic switch. Nature structural . PMID: 21102443  

  • November 29, 2010
  • 07:07 AM

Dinosaurs and Other Extinct Saurians: A Historical Perspective, the book

by Darren Naish in Tetrapod Zoology

As you'll know if you have your fingers on the throbbing pulse of dinosaur-related publications, the massive, incredibly pricey volume published by the Geological Society of London, and resulting from the 2008 meeting History of Dinosaurs and Other Fossil Saurians, now exists in dead-tree form. It's titled Dinosaurs and Other Extinct Saurians: A Historical Perspective and (in my totally unbiased opinion) is a definite must-see* for anyone interested in the historical side of Mesozoic reptile........ Read more »

  • November 29, 2010
  • 07:00 AM

November 29, 2010

by Erin Campbell in HighMag Blog

Basic research is fundamental if we want to make strides in understanding disease. Please (politely) shout this from the mountaintops and make sure your lawmakers and funding agencies understand this. Today’s image is from a paper that investigates a key player in cell scattering, which is an event very similar to cancer metastasis. Cell scattering is a term used to describe cell-cell dissociation and migration and occurs in liver development, organ regeneration, and metastasis. Cell sc........ Read more »

  • November 29, 2010
  • 06:00 AM

Pros and Cons of Social Media Use in Medicine

by Michelle Lin in Academic Life In Emergency Medicine

The American Medical Association (AMA) just released a policy on Social Media and Medical Professionalism. It focuses more on the negative aspects of social media, and much can be averted by just by using common sense:Physicians should weigh a number of considerations when maintaining a presence online:Physicians should be cognizant of standards of patient privacy and confidentiality that must be maintained in all environments, including online, and must refrain from posting identifiable patient........ Read more »

Greysen SR, Kind T, & Chretien KC. (2010) Online professionalism and the mirror of social media. Journal of general internal medicine, 25(11), 1227-9. PMID: 20632121  

  • November 29, 2010
  • 05:51 AM

New insights into Rett syndrome

by Kevin Mitchell in Wiring the Brain

A pair of papers from the lab of Fred Gage has provided new insights into the molecular and cellular processes affected in Rett syndrome. This syndrome is associated with arrested development and autistic features. It affects mainly girls, who typically show normal development until around age two, followed by a sudden and dramatic deterioration of function, regression of language skills and the emergence of autistic symptoms. It is caused mainly by mutations in the gene encoding MeCP2, which........ Read more »

Muotri AR, Marchetto MC, Coufal NG, Oefner R, Yeo G, Nakashima K, & Gage FH. (2010) L1 retrotransposition in neurons is modulated by MeCP2. Nature, 468(7322), 443-6. PMID: 21085180  

  • November 29, 2010
  • 05:33 AM

Can psychology help combat pseudoscience?

by BPS Research Digest in BPS Research Digest

From homeopathy to dodgy nutritional supplements, support for pseudoscience and quackery thrives on people believing falsely that one thing causes another, when in fact it doesn't. Meanwhile, psychologists study belief formation, and specifically illusions of control (see earlier), whereby people wrongly believe that they're controlling something when they're not. In a new paper, three psychologists at Deusto University in Bilbao argue that the psychological literature can be mined for ways........ Read more »

Matute, H., Yarritu, I., & Vadillo, M. (2010) Illusions of causality at the heart of pseudoscience. British Journal of Psychology. DOI: 10.1348/000712610X532210  

  • November 29, 2010
  • 01:48 AM

Social Media Use by Medical Students

by Dr Shock in Dr Shock MD PhD

Social software or the use of Internet (Web 2.0) for generating your own content, to connect with one another and to share and manage content with each other is used by young people. How do first year medical students use this social software? This could be important because these networks could become networks of learners [...]

Related posts:Social Media in Health and Medicine: Medlibs Round 2.7
The Risks of Online Social Networking for Students
Disclosure of substance use on social media we........ Read more »

  • November 29, 2010
  • 01:18 AM

How bacteria sort their lipoproteins (Lol!)

by Microbe Fan in Spirochetes Unwound

Bacterial lipoproteins are proteins with covalently-attached lipid molecules that anchor the protein to the cytoplasmic or outer membrane.  The lipid molecules are attached to the cysteine located at the amino terminus of the lipoprotein.  The lipoprotein's protein component, being hydrophilic (water-loving), sticks out from the membrane. Different bacterial lipoproteins participate in a variety of functions, including transport of molecules, stabilization of the cell wall, signal tran........ Read more »

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