Post List

  • February 28, 2011
  • 06:58 AM

cartilage transgenic mouse

by 96well in Reportergene

Cartilage is the flexible connective tissue between our bones, and it is mainly based of cells called chondroblasts that secrete a gel-matrix made of collagen proteins. If cartilage maturation is disrupted, diseases may develop like the painful osteoarthritis and other chondrodystrophies. Therefore, it is important to understand the dynamics of cartilage formation and maturation, and a new reporter mouse made with classic pronuclear injection of the linearized product of a bacterial recombinat........ Read more »

Maye, P., Fu, Y., Butler, D., Chokalingam, K., Liu, Y., Florer, J., Stover, M., Wenstrup, R., Jiang, X., Gooch, C.... (2011) Generation and characterization of Col10a1-mCherry reporter mice. genesis. DOI: 10.1002/dvg.20733  

  • February 28, 2011
  • 06:47 AM

The Pro-Ana Movement in the Facebook Age

by Abi Millar in Elements Science

A distressing new form of social networking, Online Negative Enabling Support Groups, is feeding the pro-anorexia movement, reports Abi Millar

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  • February 28, 2011
  • 06:30 AM

Blinged-Out Fat Blob Nanotrucks for Targeted Drug Delivery

by Sharon Neufeldt in I Can Has Science?

Targeted drug delivery is a popular area of research that melds together the disciplines of chemistry, medicine, and materials. The basic idea is to develop ways to give a person a and somehow get that medicine to go to exactly … Continue reading →... Read more »

Pornpattananangkul, D., Zhang, L., Olson, S., Aryal, S., Obonyo, M., Vecchio, K., Huang, C., & Zhang, L. (2011) Bacterial Toxin-Triggered Drug Release from Gold Nanoparticle-Stabilized Liposomes for the Treatment of Bacterial Infection. Journal of the American Chemical Society, 2147483647. DOI: 10.1021/ja111110e  

  • February 28, 2011
  • 04:57 AM

For infants, walking is more than just another step in motor development

by BPS Research Digest in BPS Research Digest

When an infant starts walking, this important achievement is more than just a milestone in motor control. According to Melissa Clearfield, the child's newfound locomotor skill arrives hand-in-hand with a raft of other changes in social behaviour and maturity. This is an unfolding, interactive process of development that before now has been little explored by psychologists.

Clearfield first had 17 non-walking infants (aged between 9 and 11 months) twice spend ten minutes exploring a 3m by 3m fl........ Read more »

  • February 27, 2011
  • 11:13 PM

Brain Measures Predict Future Improvement in Children With Dyslexia

by Livia in Reading and Word Recognition Research

Accessibility: Intermediate

Disclaimer: My PI is an author on this paper.

There is a lot of variability in outcomes for children diagnosed with dyslexia. Some children improve greatly over time, while others don't. Today, we're looking at a paper that asks whether it's possible to predict improvement in children with dyslexia.

Fumiko Hoeft and colleagues scanned children with and without dyslexia while performing a word rhyme task. They also tested the children on several reading measures......... Read more »

Hoeft F, McCandliss BD, Black JM, Gantman A, Zakerani N, Hulme C, Lyytinen H, Whitfield-Gabrieli S, Glover GH, Reiss AL.... (2011) Neural systems predicting long-term outcome in dyslexia. Proceedings of the National Academy of Sciences of the United States of America, 108(1), 361-6. PMID: 21173250  

  • February 27, 2011
  • 11:09 PM

Utricularia sucks: Aquatic carnivorous plants that evolved vacuum traps

by Ryan Kitko in Cunabulum

Utricularia, commonly known as the bladderworts, is a genus of approximately 230 species of carnivorous plants that have evolved an amazing suction trap to supplement their nutrient requirements by trapping and digesting convenient little arthropoid or crustacean packets of nitrogen, phosphorous, and other essential chemicals. Not all species are aquatic, as this cosmopolitan genus has also evolved species with lithophytic (growing in or on rocks), epiphytic, and terrestrial habits.The rootless ........ Read more »

Vincent O, Weißkopf C, Poppinga S, Masselter T, Speck T, Joyeux M, Quilliet C, & Marmottant P. (2011) Ultra-fast underwater suction traps. Proceedings. Biological sciences / The Royal Society. PMID: 21325323  

  • February 27, 2011
  • 10:26 PM

Telomerase can reverse the aging process... sort of

by Charles Daney in Science and Reason

Biologists are, at long last, beginning to understand the molecular processes responsible for aging in complex (multicellular) organisms – and to investigate ways to counteract these processes. We discussed one line of research in this recent article about a particular sirtuin (SIRT3) that helps relieve oxidative stress that can lead to DNA damage, which generally leads, in turn, to cell senescence or death.While oxidative stress is certainly a significant factor in aging, possibly the mos........ Read more »

Jaskelioff, M., Muller, F., Paik, J., Thomas, E., Jiang, S., Adams, A., Sahin, E., Kost-Alimova, M., Protopopov, A., Cadiñanos, J.... (2010) Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice. Nature, 469(7328), 102-106. DOI: 10.1038/nature09603  

  • February 27, 2011
  • 09:19 PM

hibernation is cool

by Gerty-Z in Balanced Instability

Well, that sucked! Last week was totes crazy. There was much writing and knashing of teeth, but very little sleep. But everything worked out, considering. I have promised myself that I will never again cut deadlines so close. (Alas, it is not the first time I have made such a pronouncement). Unfortunately, the weather did [...]... Read more »

Tøien Ø, Blake J, Edgar DM, Grahn DA, Heller HC, & Barnes BM. (2011) Hibernation in black bears: independence of metabolic suppression from body temperature. Science (New York, N.Y.), 331(6019), 906-9. PMID: 21330544  

  • February 27, 2011
  • 08:15 PM

Classics: Tragedy of the Commons

by CJA Bradshaw in ConservationBytes

Another one from our upcoming chapter in the book ‘Biodiversity’ to be published later this year by InTech. – Although not a conservation biology paper per se, Hardin’s classic essay (Hardin, 1968) changed the way we think about managing natural resources that lack definitive ownership. The thesis of the “tragedy of the commons” is that [...]... Read more »

Hardin, G. (1968) The Tragedy of the Commons. Science, 162(3859), 1243-1248. DOI: 10.1126/science.162.3859.1243  

  • February 27, 2011
  • 06:39 PM

Sore Throat Treatments – How Effective are Other Things

by ogremkv in Cassandra's Tears

Disclaimer, this is a layman’s review of a published review paper.  Use the treatments given here only under the advice of a doctor.  If you have a severe sore throat, or have one for longer than a few days, you … Continue reading →... Read more »

Thomas M, Del Mar C, & Glasziou P. (2000) How effective are treatments other than antibiotics for acute sore throat?. The British journal of general practice : the journal of the Royal College of General Practitioners, 50(459), 817-20. PMID: 11127175  

  • February 27, 2011
  • 03:28 PM

Omics approach shows fewer changes from GE than breeding and environment

by David Tribe in Biofortified

From GMO Pundit. Ricroch AE, Bergé JB, & Kuntz M (2011). Evaluation of genetically engineered crops using transcriptomic, proteomic and metabolomic profiling techniques. Plant physiology PMID: 21350035 The authors conducted a literature survey on 44 recent “omic” comparisons between GE and non-GE crop lines. Those profiling techniques (transcriptomics, proteomics, and metabolomics) have been increasingly applied to the analysis of genetically engineered (GE) crop plants with regard to t........ Read more »

  • February 27, 2011
  • 03:27 PM

Speaking two languages can delay the onset of Alzheimer’s Disease

by Richard Masters in Elements Science

Lifelong bilinguals develop the neurodegenerative disease five years later than those who speak only one language, reports Richard Masters

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  • February 27, 2011
  • 02:43 PM

Cod – the thermometers of the Atlantic

by Jennifer Appleton in Elements Science

A look into the possible effects of climate change and how this might change our cod supplies by Jennifer Appleton.

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Righton, D., Andersen, K., Neat, F., Thorsteinsson, V., Steingrund, P., Svedäng, H., Michalsen, K., Hinrichsen, H., Bendall, V., Neuenfeldt, S.... (2010) Thermal niche of Atlantic cod Gadus morhua: limits, tolerance and optima. Marine Ecology Progress Series, 1-13. DOI: 10.3354/meps08889  

  • February 27, 2011
  • 11:27 AM

Got beef with worms?

by zacharoo in Lawn Chair Anthropology

Photo: {}, by Eric Rottinger at kahikai.orgFlipping through the current issue of Current Biology, it sounds like someone has some serious beef with acoelomorph flatworms. Apparently these critters have been used as a model for the 'missing link' between simple-bodied cnidarians (like jellyfish) and bilaterians (bilaterally symmetrical animals like you and me and flies and fish, and really a good deal of animal biodiversity); and this may be pr........ Read more »

  • February 27, 2011
  • 11:19 AM

Social ties and recovery go together like ham and eggs

by PeaPod in Binge Inking

The homeless face particular challenges on the road to recovery. This US research sought to answer how social ties influence the decision to enter and continue with treatment for substance use disorders in a sample of homeless men. Could what the researchers found be applied in treatment settings in the UK?... Read more »

  • February 27, 2011
  • 10:56 AM

Exploring Phobias in the Brain. An Introduction.

by neurobites in Neurobites

My fellow neuro-enthusiasts! I have a special post for you this time☺. We have received a special request to explore the issue of phobias. In the interest of turning the world into neurogeeks we must deliver. That and we are suckers for a pretty face. Have you or a “friend” let out a childish, high-pitched [...]... Read more »

Dean Mobbs, Rongjun Yu, James B.Rowe, Hannah Eich, Oriel FeldmanHall, and Tim Dalgleish. (2010) Neural activity associated with monitoring the oscillating threat value of a tarantula. PNAS, 107(47). info:/

  • February 27, 2011
  • 10:37 AM

arxiv stuffs a wormhole with perfect fluids

by Greg Fish in weird things

Some bloggers just can’t resist going back to the same rich source of things just begging to be really torn into and dissected, and I’m no exception. After growling about the papers being posted and promoted on arXiv, I still find myself going through some of the more bizarre and out of left field proposals [...]... Read more »

V. Dzhunushaliev, V. Folomeev, B. Kleihaus, & J. Kunz. (2011) A Star Harbouring a Wormhole at its Center. n/a. arXiv: 1102.4454v1

  • February 27, 2011
  • 09:56 AM

Deprived, Deranged and Disrupted

by perishedcore in Changing Heart and Mind

Research about sleep inevitably leads to circadian rhythms and CLOCK genes. One group of researchers goes farther and suggests that 24 hour exposure to light beyond that produced by the denizens of space and the moon and demands which interfere or replace traditional sleep wake cycles may be doing damage beyond imagination. Circadian (daily) rhythms [...]... Read more »

Karatsoreos IN, Bhagat S, Bloss EB, Morrison JH, & McEwen BS. (2011) Disruption of circadian clocks has ramifications for metabolism, brain, and behavior. Proceedings of the National Academy of Sciences of the United States of America, 108(4), 1657-62. PMID: 21220317  

  • February 27, 2011
  • 07:43 AM

Patients, pathogens, ecosystems

by iayork in Mystery Rays from Outer Space

“A terrified man realizing he has just contracted the plague, surrounded by a group of people.” By E.M. Ward, 1848. Even the most lethal pathogens we know of don’t kill every single infected individual.1. Sometimes this is because the pathogen that infects the person is relatively weak. Sometimes it’s because the dose was low. And [...]... Read more »

  • February 27, 2011
  • 02:47 AM

Best Acknowledgment Ever

by teofilo in Gambler's House

In 1978 H. Martin Wobst of the University of Massachusetts at Amherst published a short article in American Antiquity entitled “The Archaeo-Ethnology of Hunter-Gatherers or the Tyranny of the Ethnographic Record in Archaeology.”  Despite the evocative title, the article itself is a highly theoretical argument about the proper relationship between archaeology and ethnography that is [...]... Read more »

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