Post List

  • January 18, 2011
  • 02:00 AM

How media obsession fuels public fascination with the ‘Yorkshire Ripper’ yet leaves other serial killers to serve their time as almost unknowns

by SAGE Insight in SAGE Insight

When serial killers go unseen: The case of Trevor Joseph Hardy From Crime, Media and Culture UK headlines last week highlighted news regarding the denied plea of the ‘Yorkshire Ripper’ and confirmation he will spend all his life behind bars. This serial killer always sparks huge public interest. The article examines the differences in the [...]... Read more »

Wilson, D., Tolputt, H., Howe, N., & Kemp, D. (2010) When serial killers go unseen: The case of Trevor Joseph Hardy. Crime, Media, Culture, 6(2), 153-167. DOI: 10.1177/1741659010369952  

  • January 17, 2011
  • 10:11 PM

Goblin Shark: Prehistoric monster from the deep

by beredim in Strange Animals

Mitsukurina owstoni is a weird and scary species of shark, commonly known as the goblin shark.

It is very distinct from other sharks and has many unique and unshark-like traits, like its pink color! .

The species is often described as a "living fossil", thanks to its prehistoric appearance and its ancient lineage.... Read more »

Masai H, Sato Y, & Aoki M. (1973) The brain of Mitsukurina owstoni. Journal fur Hirnforschung, 14(6), 493-500. PMID: 4792175  

  • January 17, 2011
  • 06:46 PM

The bumbebee tit

by Africa Gomez in BugBlog

Today I watched a pair of Blue Tits paying a lot of attention to the inflorescences of Mahonia in the local park, coming back to them again and again. What were they doing? If you hear nectar feeding in birds you would most likely think on hummingbirds and the tropics. However, several bird groups feed on nectar in addition to hummingbirds, honeyeaters and sunbirds. In Australia, they are actually the main flower pollinators. Although nectar feeding behaviour is far less widespread, it does happ........ Read more »

  • January 17, 2011
  • 02:51 PM

Does it hurt when I do this?

by Lorimer Moseley in BodyInMind

By Steve Kamper I’m a physiotherapist, as physios (and we’re not alone here) we love to poke and prod our patients with our fingers and ask if it hurts. Anatomical training and experience tells us exactly which part we are poking and the knowing nod of the head followed by a somber and considered ‘aah [...]... Read more »

  • January 17, 2011
  • 12:17 PM

Death Song of an Iceberg

by clark in Now Hear This

Last year, University of Washington oceanographer Seelye Martin and his colleagues reported the discovery of an iceberg graveyard: a previously unreported underwater shoal near the Antarctic coast on which large icebergs occasionally run aground and break apart. One notable victim was B-15A, a Rhode Island-size iceberg that was the largest remnant of a far larger, 1000-foot [...]... Read more »

Martin, S., Drucker, R., Aster, R., Davey, F., Okal, E., Scambos, T., & MacAyeal, D. (2010) Kinematic and seismic analysis of giant tabular iceberg breakup at Cape Adare, Antarctica. Journal of Geophysical Research, 115(B6). DOI: 10.1029/2009JB006700  

  • January 17, 2011
  • 11:35 AM

Salmon, scent and going home again

by GrrlScientist in Maniraptora

Did you know that salmon rely on their sense of smell (olfaction) for nearly every aspect of their lives, from locating food to avoiding predators? ... Read more »

W.J. Wisby, & A.D. Hasler. (1954) Effect of olfactory occlusion on migrating silver salmon (O. kisutch). Journal of the Fisheries Research Board of Canada, 472-478. info:/

Tierney, K., Sampson, J., Ross, P., Sekela, M., & Kennedy, C. (2008) Salmon Olfaction is Impaired by an Environmentally Realistic Pesticide Mixture. Environmental Science , 42(13), 4996-5001. DOI: 10.1021/es800240u  

  • January 17, 2011
  • 11:30 AM

What Do Antidepressants Do in Healthy Brains?

by William Yates, M.D. in Brain Posts

The easiest answer to the title question is “cause side effects”.  A more important theoretical and practical aspect of this question is: Do antidepressants have a general property experienced by everyone or are their effects only seen in the presence of depression?  Antidepressant drugs have research support for a variety of non-depression indications including: chronic pain, fibromyalgia, migraine prophylaxis, irritable bowel syndrome and pathological crying and laughing.&nb........ Read more »

Serretti A, Calati R, Goracci A, Di Simplicio M, Castrogiovanni P, & De Ronchi D. (2010) Antidepressants in healthy subjects: what are the psychotropic/psychological effects?. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 20(7), 433-53. PMID: 20079613  

  • January 17, 2011
  • 11:12 AM

Darwin meets Gibbs: thermodynamics of natural selection

by Vasili Hauryliuk in stringent response

In order to perform its function, protein should be properly folded. Therefore stability of this proteins’ native state is crucial for its function. Denatured protein can be toxic the cell and requires specialised machinery to degrade it, thus compromising cells fitness. Having a denatured protein is not equal to just not having a functional one, it is equal to not having a functional one and hiving some costly junk.Since stability is so crucial for proteins function, it must leave its trace i........ Read more »

Fu H, Grimsley G, Scholtz JM, & Pace CN. (2010) Increasing protein stability: importance of DeltaC(p) and the denatured state. Protein science : a publication of the Protein Society, 19(5), 1044-52. PMID: 20340133  

Geiler-Samerotte KA, Dion MF, Budnik BA, Wang SM, Hartl DL, & Drummond DA. (2011) Misfolded proteins impose a dosage-dependent fitness cost and trigger a cytosolic unfolded protein response in yeast. Proceedings of the National Academy of Sciences of the United States of America, 108(2), 680-5. PMID: 21187411  

Loladze VV, Ermolenko DN, & Makhatadze GI. (2001) Heat capacity changes upon burial of polar and nonpolar groups in proteins. Protein science : a publication of the Protein Society, 10(7), 1343-52. PMID: 11420436  

  • January 17, 2011
  • 11:00 AM

PI3K inhibition overcomes HGF-mediated resistance to EGFR-TKIs in EGFR mutant lung cancer

by Sally Church in Pharma Strategy Blog

PI3-kinase inhibition is becoming quite a hot topic in cancer research – for those of you interested in learning about the compounds in this area, you can find out more from previous posts here and here as background information before … Continue reading →... Read more »

Kobayashi, S., Boggon, T., Dayaram, T., Jänne, P., Kocher, O., Meyerson, M., Johnson, B., Eck, M., Tenen, D., & Halmos, B. (2005) Mutation and Resistance of Non–Small-Cell Lung Cancer to Gefitinib . New England Journal of Medicine, 352(8), 786-792. DOI: 10.1056/NEJMoa044238  

Engelman, J., Zejnullahu, K., Mitsudomi, T., Song, Y., Hyland, C., Park, J., Lindeman, N., Gale, C., Zhao, X., Christensen, J.... (2007) MET Amplification Leads to Gefitinib Resistance in Lung Cancer by Activating ERBB3 Signaling. Science, 316(5827), 1039-1043. DOI: 10.1126/science.1141478  

Turke, A., Zejnullahu, K., Wu, Y., Song, Y., Dias-Santagata, D., Lifshits, E., Toschi, L., Rogers, A., Mok, T., & Sequist, L. (2010) Preexistence and Clonal Selection of MET Amplification in EGFR Mutant NSCLC. Cancer Cell, 17(1), 77-88. DOI: 10.1016/j.ccr.2009.11.022  

  • January 17, 2011
  • 09:15 AM

Learning What Not to Say

by gameswithwords in Games with Words

A troubling fact about language is that words can be used in more than one way. For instance, I can throw a ball, I can throw a party, and I can throw a party that is also a ball.

These cats are having a ball.
The Causative Alternation

Sometimes the relationship between different uses of a word is completely arbitrary. If there's any relationship between the different meanings of ball, most people don't know it. But sometimes there are straightforward, predictable relationships. For instance, ........ Read more »

Gropen, J., Pinker, S., Hollander, M., Goldberg, R., & Wilson, R. (1989) The Learnability and Acquisition of the Dative Alternation in English. Language, 65(2), 203. DOI: 10.2307/415332  

Ben Ambridge, Julian M. Pine, & Caroline F. Rowland. (2011) Children use verb semantics to retreat from overgeneralization errors. Cognitive Linguistics. info:/

  • January 17, 2011
  • 08:34 AM

Merger Success and Supply Chain Integration

by Daniel Dumke in SCRM Blog - Supply Chain Risk Management

What are the major obstacles to a successful merger? Today I'll have a look at the 2003 article by Langabeer and Seifert. The authors argue that supply chain integration plays a major role before, during and after the merger.

Why is the Supply Chain Key?
The authors start by making the case for the supply chain as one of the major drivers of financial performance in a company. After analyzing quantitative data from 400 mergers during a ten-year period, exploring relationships between merge........ Read more »

Langabeer, J., & Seifert, D. (2003) Supply Chain Integration: The Key to Merger Success. Supply Chain Management Review. info:/

  • January 17, 2011
  • 08:25 AM

Seeing the big picture of RNA virus evolution

by Connor Bamford in The Rule of 6ix

From both a medical and a scientific viewpoint, the evolution of viruses is extremely important to us;  viral adaptation to their ever changing environment is responsible for major morbidity and mortality worldwide so maybe studying this  may allow us to predict virus evolution in the future and may help prevent pandemics occuring? We kind of [...]... Read more »

Kitchen A, Shackelton LA, & Holmes EC. (2011) Family level phylogenies reveal modes of macroevolution in RNA viruses. Proceedings of the National Academy of Sciences of the United States of America, 108(1), 238-43. PMID: 21173251  

  • January 17, 2011
  • 07:19 AM

Vital topics forum in AA: ‘Nature and the human’

by gregdowney in Neuroanthropology

The question of ‘human nature’ is a fraught one for many anthropologists, especially those of us who pay special attention to human variation, Darwinian theory, and dynamic approaches to diversity in developmental questions.
The very concept ‘human nature’ can be the theoretical equivalent of the double-bind question, ‘So can you confirm that you no longer are a Creationist?’  Even conceding to respond to the question places us in a position where we wind up between the Scylla of th........ Read more »

Fuentes, A., Marks, J., Ingold, T., Sussman, R., Kirch, P., Brumfiel, E., Rapp, R., Ginsburg, F., Nader, L., & Kottak, C. (2010) On Nature and the Human. American Anthropologist, 112(4), 512-521. DOI: 10.1111/j.1548-1433.2010.01271.x  

  • January 17, 2011
  • 07:13 AM

Coffee helps women cope with stressful meetings but has the opposite effect on men

by BPS Research Digest in BPS Research Digest

For men working together, stress plus coffee could be toxic
If a meeting becomes stressful, does it help, or make things worse, if team members drink lots of coffee? A study by Lindsay St. Claire and colleagues that set out to answer this question has uncovered an unexpected sex difference. For two men collaborating or negotiating under stressful circumstances, caffeine consumption was bad news, undermining their performance and confidence. By contrast, for pairs of women, drinking caffeine of........ Read more »

  • January 17, 2011
  • 07:11 AM

Arcade Games Biotic Style

by avi_wener in American Biotechnologist

We found a great post this past weekend on which we thought we’d share with you. Author David Zax describes an interactive video game designed by researchers in the bioengineering department of Stanford University that uses living cells as part of the game mechanics. These “Biotic Games” are played much like any arcade classic [...]... Read more »

Riedel-Kruse IH, Chung AM, Dura B, Hamilton AL, & Lee BC. (2011) Design, engineering and utility of biotic games. Lab on a chip, 11(1), 14-22. PMID: 21085736  

  • January 17, 2011
  • 07:02 AM

Martin Luther King, Jr. & Eliot Spitzer: On letting people off the hook [Part I]

by Rita Handrich in The Jury Room

Martin Luther King, Jr. committed adultery. So did Eliot Spitzer. And although CNN’s David Gergen insists he did not compare Eliot Spitzer with Martin Luther King, Jr., we know of some researchers who did. Effron & Monin (2010) wondered what made the difference in how we decide to punish some people for bad behavior let others [...]

Related posts:Eliot Spitzer, Uncivil Behavior & Possibilities of Redemption
Apology redux: Doing it right (and doing it wrong)
Got morals?
... Read more »

Effron DA, & Monin B. (2010) Letting people off the hook: when do good deeds excuse transgressions?. Personality and social psychology bulletin, 36(12), 1618-34. PMID: 20978222  

  • January 17, 2011
  • 07:00 AM

January 17, 2011

by Erin Campbell in HighMag Blog

Today’s image is from a paper describing a new microscopy method that allows the best of both worlds – fluorescent AND electron microscopy. The images in this paper are fantastic, but I especially can’t wait to see what images are down the road using this new method. ........ Read more »

Kukulski, W., Schorb, M., Welsch, S., Picco, A., Kaksonen, M., & Briggs, J. (2011) Correlated fluorescence and 3D electron microscopy with high sensitivity and spatial precision. originally published in The Journal of Cell Biology, 192(1), 111-119. DOI: 10.1083/jcb.201009037  

  • January 17, 2011
  • 05:38 AM

A White-tailed eagle in southern England

by Darren Naish in Tetrapod Zoology

The big buzz here in Hampshire (southern England) at the moment is the recent arrival of a White-tailed eagle Haliaeetus albicilla. This magnificent raptor - it can have a wingspan of 2.4 m and is one of the biggest eagles in the world - is historically extinct in England, but individuals still appear here on occasion [image of the Hampshire bird shown here by Darren Crain].

A member of the 'sea eagle' clade Haliaeetus, the White-tailed eagle appears to be the sister-species of North Americ........ Read more »

  • January 17, 2011
  • 04:26 AM

Ophiocordyceps unilateralis: Horrifying ant parasite

by beredim in Strange Animals

Ophiocordyceps unilateralis (also known as cordyceps unilateralis)is a bizarre parasitic fungus that turns ants into zombies in order to ensure its survival. Interestingly, another yet unidentified fungus protects ants by parasitizing on the zombie-turning O. unilateralis !... Read more »

Andersen, S., Gerritsma, S., Yusah, K., Mayntz, D., Hywel‐Jones, N., Billen, J., Boomsma, J., & Hughes, D. (2009) The Life of a Dead Ant: The Expression of an Adaptive Extended Phenotype. The American Naturalist, 174(3), 424-433. DOI: 10.1086/603640  

Hughes, D., Wappler, T., & Labandeira, C. (2010) Ancient death-grip leaf scars reveal ant-fungal parasitism. Biology Letters, 7(1), 67-70. DOI: 10.1098/rsbl.2010.0521  

Andersen, S., Ferrari, M., Evans, H., Elliot, S., Boomsma, J., & Hughes, D. (2012) Disease Dynamics in a Specialized Parasite of Ant Societies. PLoS ONE, 7(5). DOI: 10.1371/journal.pone.0036352  

Kittakoop, P., Punya, J., Kongsaeree, P., Lertwerawat, Y., Jintasirikul, A., Tanticharoen, M., & Thebtaranonth, Y. (1999) Bioactive naphthoquinones from Cordyceps unilateralis. Phytochemistry, 52(3), 453-457. DOI: 10.1016/S0031-9422(99)00272-1  

Sung, G., Hywel-Jones, N., Sung, J., Luangsa-ard, J., Shrestha, B., & Spatafora, J. (2007) Phylogenetic classification of Cordyceps and the clavicipitaceous fungi. Studies in Mycology, 57(1), 5-59. DOI: 10.3114/sim.2007.57.01  

Andersen SB, Gerritsma S, Yusah KM, Mayntz D, Hywel-Jones NL, Billen J, Boomsma JJ, & Hughes DP. (2009) The life of a dead ant: the expression of an adaptive extended phenotype. The American naturalist, 174(3), 424-33. PMID: 19627240  

  • January 17, 2011
  • 04:00 AM

Copernicus and the Star that was bigger than the Universe

by Alun in AlunSalt

I’ve been trying to watch Cosmos by Carl Sagan. I’ve never seen it and it’s proving to be a bit of a struggle. He definitely can write. Some of the sequences are fantastic, but some of it is badly dated. The thing that really grates to me is his dismissal of Ptolemy and his geocentric... Read more »

Graney, C.M. (2010) The Telescope Against Copernicus: Star Observations by Riccioli Supporting a Geocentric Universe. Journal for the History of Astronomy, 41(4), 453-467. info:/

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