A very interesting part of Supply Chain Risk Management deals with the impact of uncertainty on the supply chain design process. Van der Vorst and Beulens (2002) address this topic, and focus on the redesign of supply chains.
They claim that sources of uncertainty can be a key driver for chain redesign and after analyzing the literature and own research (case study) they present a tool for supply chain redesign where the sources of uncertainty support the selection of the relevant strategy.... Read more »
Vorst, J., & Beulens, A. (2002) Identifying sources of uncertainty to generate supply chain redesign strategies. International Journal of Physical Distribution , 32(6), 409-430. DOI: 10.1108/09600030210437951
About 15 minutes after I wrote my last article on influenza variation, I was reading the Journal of Virology and ran across another paper1 on the same thing, that at least partly addresses some of the missing points in the earlier ones.
To brutally truncate my earlier comments: influenza should generate a huge number of mutants [...]... Read more »
Hoelzer, K., Murcia, P., Baillie, G., Wood, J., Metzger, S., Osterrieder, N., Dubovi, E., Holmes, E., & Parrish, C. (2010) Intrahost Evolutionary Dynamics of Canine Influenza Virus in Naive and Partially Immune Dogs. Journal of Virology, 84(10), 5329-5335. DOI: 10.1128/JVI.02469-09
Kuroda, M., Katano, H., Nakajima, N., Tobiume, M., Ainai, A., Sekizuka, T., Hasegawa, H., Tashiro, M., Sasaki, Y., Arakawa, Y.... (2010) Characterization of Quasispecies of Pandemic 2009 Influenza A Virus (A/H1N1/2009) by De Novo Sequencing Using a Next-Generation DNA Sequencer. PLoS ONE, 5(4). DOI: 10.1371/journal.pone.0010256
Novella, I., Presloid, J., Zhou, T., Smith-Tsurkan, S., Ebendick-Corpus, B., Dutta, R., Lust, K., & Wilke, C. (2010) Genomic Evolution of Vesicular Stomatitis Virus Strains with Differences in Adaptability. Journal of Virology, 84(10), 4960-4968. DOI: 10.1128/JVI.00710-09
Change is quite in the air today, whether it be climate change or human induced habitat shifts. What’s a species in the wild to do? Biologists naturally worry about loss of biodiversity a great deal, and many non-biologist humans rather high up on Maslow’s hierarchy of needs also care. And yet species loss, or the [...]... Read more »
Chevin L-M, Lande R, & Mace GM. (2010) Adaptation, Plasticity, and Extinction in a Changing Environment: Towards a Predictive Theory. PLoS Biol. info:/10.1371/journal.pbio.1000357
The football World Cup in South Africa is almost upon us and the clock is ticking down on London 2012. It's a timely moment to ask: why, when it costs a country billions of pounds to host a major international sporting event, do they bother?The usual argument is that it's all about the legacy - the lasting economic benefit. But according to two economists, Georgios Kavetsos and Stefan Szymanski, the evidence for this simply isn't there. For example, there's research showing that the economic ben........ Read more »
Kavetsos, G., & Szymanski, S. (2010) National well-being and international sports events. Journal of Economic Psychology, 31(2), 158-171. DOI: 10.1016/j.joep.2009.11.005
A new study by Thomas von Lengerke and colleagues from the University of Hannover, Germany, published in Psychosomatic Medicine, looks at the impact of socioeconomic status (SES) on direct medical costs for severe obesity in Germany (which has a mixed private and public insurance based health care system).... Read more »
von Lengerke T, John J, Mielck A, & KORA Study Group. (2010) Excess direct medical costs of severe obesity by socioeconomic status in German adults. Psycho-social medicine. PMID: 20421952
For the land manager, fire represents a potentially valuable tool in controlling invasive species and restoring native ecosystems. But one of the challenges of utilizing fire in restoration is predicting how plants will ultimately respond to the treatment and planning accordingly...... Read more »
Pyke, D., Brooks, M., & D'Antonio, C. (2010) Fire as a Restoration Tool: A Decision Framework for Predicting the Control or Enhancement of Plants Using Fire. Restoration Ecology. DOI: 10.1111/j.1526-100X.2010.00658.x
'Colour-changing-card-me' confused about the combination of a new paper and a much older report on the effect of magic tricks on children! A post that looks at the questions about whether popular appeal of magic demonstrations really means health or educational benefits.... Read more »
Hart R, & Walton M. (2010) Magic as a therapeutic intervention to promote coping in hospitalized pediatric patients. Pediatric nursing, 36(1), 11. PMID: 20361440
In the past I have focused on reviewing newly published literature, but I have decided to periodically take a look back at some "classic" zoology papers. Defining "classic" is difficult, I am using the slightly arbitrary criteria that the paper...... Read more »
Jaeger, R. (1981) Dear Enemy Recognition and the Costs of Aggression between Salamanders. The American Naturalist, 117(6), 962. DOI: 10.1086/283780
If David Cameron wants to beat Gordon Brown next month, he might want to play a lot of tennis. According to this paper, anyway, gestures and small movements are enough to give people a clear impression of a candidate's overall health—and he who seems healthiest will get their vote.
It's another blow to the notion that we know what we are doing when we vote, which has taken a pounding in recent research. In 2008, for instance, Jonah Berger and his colleagues reported that where people vo........ Read more »
Kramer, R., Arend, I., & Ward, R. (2010) Perceived health from biological motion predicts voting behaviour. The Quarterly Journal of Experimental Psychology, 63(4), 625-632. DOI: 10.1080/17470210903490977
Berger, J., Meredith, M., & Wheeler, S. (2008) From the Cover: Contextual priming: Where people vote affects how they vote. Proceedings of the National Academy of Sciences, 105(26), 8846-8849. DOI: 10.1073/pnas.0711988105
A new therapy based on RNA interference (RNAi) successfully reduces respiratory syncytial virus (RSV) infection in humans. The study, published free online in PNAS, demonstrates that therapeutic RNAi-based drugs are clinically effective, and suggests that similar ‘silencing’ therapies could be useful against other respiratory pathogens. RSV is an RNA virus that infects the lungs to [...]... Read more »
DeVincenzo, J., Lambkin-Williams, R., Wilkinson, T., Cehelsky, J., Nochur, S., Walsh, E., Meyers, R., Gollob, J., & Vaishnaw, A. (2010) A randomized, double-blind, placebo-controlled study of an RNAi-based therapy directed against respiratory syncytial virus. Proceedings of the National Academy of Sciences. DOI: 10.1073/pnas.0912186107
It seems like every few months we hear about some new diet that is supposed to help us melt away the pounds and add years to our lives. But how different are these diets, really? I’ve already discussed studies suggesting that the DASH diet does indeed appear to decrease risk of heart disease and reduce [...]... Read more »
Trichopoulou, A. (2003) Adherence to a Mediterranean Diet and Survival in a Greek Population. New England Journal of Medicine, 348(26), 2599-2608. DOI: 10.1056/NEJMoa025039
Sofi, F., Cesari, F., Abbate, R., Gensini, G., & Casini, A. (2008) Adherence to Mediterranean diet and health status: meta-analysis. BMJ, 337(sep11 2). DOI: 10.1136/bmj.a1344
Spiders are key links in the transfer of pollutants from aquatic to terrestrial food webs.... Read more »
Walters, D., Mills, M., Fritz, K., & Raikow, D. (2009) Spider-Mediated Flux of PCBs from Contaminated Sediments to Terrestrial Ecosystems and Potential Risks to Arachnivorous Birds . Environmental Science , 2147483647. DOI: 10.1021/es9023139
Anxiety and False Assurances First
Relief Third, Hopefully
Large rocks hurtle towards our heads. What happens? We duck. The process, however, is complex.
It involves answering two questions: what is that? and how do I behave? This anthropomorphic perspective is backwards and flawed. It suggests searching (for what, that and how) and then behaving.
The whole process (what, that and how) can be instinctive, like ducking the rock: body-as-it-was, object, body-as-it-is.1 Usual........ Read more »
Brewin, C., Gregory, J., Lipton, M., & Burgess, N. (2010) Intrusive images in psychological disorders: Characteristics, neural mechanisms, and treatment implications. Psychological Review, 117(1), 210-232. DOI: 10.1037/a0018113
Tedeschi, R., & Calhoun, L. (2004) TARGET ARTICLE: "Posttraumatic Growth: Conceptual Foundations and Empirical Evidence". Psychological Inquiry, 15(1), 1-18. DOI: 10.1207/s15327965pli1501_01
Brewin, C., Dalgleish, T., & Joseph, S. (1996) A dual representation theory of posttraumatic stress disorder. Psychological Review, 103(4), 670-686. DOI: 10.1037//0033-295X.103.4.670
Vitamin D is a hot topic lately, and many observational studies have linked it positively with a reduction in various disease risks. However, we should be careful not to tout it as a panacea without large controlled studies and a deeper understanding of how it regulates various endogenous processes.
A recent publication studying UV radiation exposure [...]... Read more »
Becklund BR, Severson KS, Vang SV, & DeLuca HF. (2010) UV radiation suppresses experimental autoimmune encephalomyelitis independent of vitamin D production. Proceedings of the National Academy of Sciences of the United States of America, 107(14), 6418-23. PMID: 20308557
New research out of the Oregon Health and Science University may explain the discrepancy between the theory and reality of dieting. They found that, at least in some of our closest relatives, cutting calories isn't enough to lose weight because the body compensates for the reduced intake by lowering activity levels. Image credit: iamchenelle, flickr... Read more »
Sullivan, E., & Cameron, J. (2010) A rapidly occurring compensatory decrease in physical activity counteracts diet-induced weight loss in female monkeys. AJP: Regulatory, Integrative and Comparative Physiology, 298(4). DOI: 10.1152/ajpregu.00617.2009
I’ve written rather a lot about rates of forest loss around the world, including accumulated estimates of tropical forest loss and increasing fragmentation/loss in the boreal forest (see Bradshaw et al. 2009 Front Ecol Evol & Bradshaw et al. 2009 Trends Ecol Evol). For the tropics in particular, we used the index that an area [...]... Read more »
When it comes to chemistry, surfaces are the places to be. Where two phases meet, interesting stuff is bound to happen. One of the phase interactions that received increased attention during the last few years is the peculiar meeting of a liquid and a solid. One rather interesting phenomenon encountered here is the lotus effect, [...]... Read more »
Voïtchovsky, K., Kuna, J., Contera, S., Tosatti, E., & Stellacci, F. (2010) Direct mapping of the solid–liquid adhesion energy with subnanometre resolution. Nature Nanotechnology. DOI: 10.1038/NNANO.2010.67
The cause of pancreatic cancer is still unknown, although there are risk factors involved, such as increased exposure to tobacco smoke and a family history of the disease. It is usually detected late when advanced stage disease has set in...... Read more »
Goicoechea, S., Bednarski, B., Stack, C., Cowan, D., Volmar, K., Thorne, L., Cukierman, E., Rustgi, A., Brentnall, T., Hwang, R.... (2010) Isoform-Specific Upregulation of Palladin in Human and Murine Pancreas Tumors. PLoS ONE, 5(4). DOI: 10.1371/journal.pone.0010347
by gkobs in Promega Connections
Pull-down assays probe interactions between a protein of interest that is expressed as fusion protein (e.g., (e.g., bait) and the potential interacting partners (prey). In a pull-down assay one protein partner is expressed as a fusion protein (e.g., bait protein) in E. coli and then immobilized using an affinity ligand specific for the fusion tag. [...]... Read more »
Tonhosolo R, D'Alexandri FL, de Rosso VV, Gazarini ML, Matsumura MY, Peres VJ, Merino EF, Carlton JM, Wunderlich G, Mercadante AZ.... (2009) Carotenoid biosynthesis in intraerythrocytic stages of Plasmodium falciparum. The Journal of biological chemistry, 284(15), 9974-85. PMID: 19203994
Dennis MD, Person MD, & Browning KS. (2009) Phosphorylation of plant translation initiation factors by CK2 enhances the in vitro interaction of multifactor complex components. The Journal of biological chemistry, 284(31), 20615-28. PMID: 19509420
Ahmed NT, Gao C, Lucker BF, Cole DG, & Mitchell DR. (2008) ODA16 aids axonemal outer row dynein assembly through an interaction with the intraflagellar transport machinery. The Journal of cell biology, 183(2), 313-22. PMID: 18852297
Gembka A, Toueille M, Smirnova E, Poltz R, Ferrari E, Villani G, & Hübscher U. (2007) The checkpoint clamp, Rad9-Rad1-Hus1 complex, preferentially stimulates the activity of apurinic/apyrimidinic endonuclease 1 and DNA polymerase beta in long patch base excision repair. Nucleic acids research, 35(8), 2596-608. PMID: 17426133
Installment #2 in the mini-series on multilingual signage
Much of the signage that can be found in contemporary public spaces is commercial. It is a form of advertising, and language choice in commercial signage such as shop names is a good indicator of the values associated with a particular language. The basic idea is that the [...]... Read more »
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