Post List

  • January 24, 2011
  • 12:00 PM

Some Like it Hot

by Moselio Schaechter in Small Things Considered

by S. Marvin Friedman

How can thermophilic bacteria not only survive, but actually proliferate, at elevated temperatures that would be lethal to all other forms of life? After extensive research during the past five decades, this question has been answered in a general way, but the molecular basis for this unusual capability has not been clearly resolved. Thermophiles [I use this term to include both thermophiles (optimal growth temperatures of 50-70 °C) and hyperthermophiles (optimal gro........ Read more »

  • January 24, 2011
  • 11:12 AM

The ecological consequences of industrial kelp harvesting

by Rob Goldstein in Conservation Maven

Kelp forests provide important habitat for numerous invertebrates, fish, birds and marine mammals. The ecological consequences of industrial harvest of this habitat has not been fully evaluated. Now a recent study has demonstrated that there is justified cause for concern. The study revealed that the removal of these habitats has multi-trophic effects...... Read more »

Lorentsen, S., Sjøtun, K., & Grémillet, D. (2010) Multi-trophic consequences of kelp harvest. Biological Conservation, 143(9), 2054-2062. DOI: 10.1016/j.biocon.2010.05.013  

  • January 24, 2011
  • 10:46 AM

How Soccer Explains the NICU

by Rob Mitchum in ScienceLife

At many levels of medicine, it’s important for physicians to make predictions about their patient’s future. Will their disease or condition worsen? Will this treatment or that treatment be more effective in curing them? How much longer does a patient have to live? Such decisions are especially important for pediatricians in the NICU, the neonatal [...]... Read more »

Meadow, W., Meadow, X., Tanz, R., Lagatta, J., & Lantos, J. (2011) The value of a trial of therapy - football as a ‘proof-of-concept’. Acta Paediatrica, 100(2), 167-169. DOI: 10.1111/j.1651-2227.2010.02113.x  

Meadow W, Lagatta J, Andrews B, Caldarelli L, Keiser A, Laporte J, Plesha-Troyke S, Subramanian M, Wong S, Hron J.... (2008) Just, in time: ethical implications of serial predictions of death and morbidity for ventilated premature infants. Pediatrics, 121(4), 732-40. PMID: 18381538  

  • January 24, 2011
  • 10:41 AM

In Jury Selection, Pay All Kinds of Attention to the Man Behind the Curtain

by Persuasion Strategies in Persuasive Litigator

By: Dr. Ken Broda-Bahm - Watching the Wizard of Oz recently with my three (and a half!)-year-old daughter, we came to the familiar scene of the fearless Toto interrupting the Wizard’s speech by pulling back the curtain on a man furiously working levers and wheels. When Dorothy and company ignore the instruction to “pay no attention to the man behind the curtain,” it becomes clear that what we see of the ‘wizard’ is an elaborate façade. There is a similar façade at work during jury se........ Read more »

Chang, L, . (2010) Comparing oral interviewing with self-administered computerized questionnaires. Public Opinion Quarterly, 1-14. info:/

  • January 24, 2011
  • 10:05 AM

Why does sorafenib work in HCC but sunitinib does not?

by Sally Church in Pharma Strategy Blog

That was the question from a reader that greeted me in my inbox recently, it’s a good point.   Sorafenib has received FDA approval in this indication, while Pfizer terminated their phase III trial of sunitinib in HCC for futility … Continue reading →... Read more »

Nagai, T., Arao, T., Furuta, K., Sakai, K., Kudo, K., Kaneda, H., Tamura, D., Aomatsu, K., Kimura, H., Fujita, Y.... (2011) Sorafenib Inhibits the Hepatocyte Growth Factor-Mediated Epithelial Mesenchymal Transition in Hepatocellular Carcinoma. Molecular Cancer Therapeutics, 10(1), 169-177. DOI: 10.1158/1535-7163.MCT-10-0544  

  • January 24, 2011
  • 09:39 AM

Process oriented Approach to Supply Chain Risk Management

by Daniel Dumke in SCRM Blog - Supply Chain Risk Management

Supply Chain Risk Management started from the need to better control the risks within Supply and Demand Networks. The processes in (Corporate) Risk Management have been developed and convene in the classic, cyclic processes:Risk IdentificationRisk AssessmentMeasures (Development and Implementation)Risk Monitoring

Hallikas et al. (2004) tried to transfer this process into the supply chain setting.Figure 1: Risk Diagramm (Hallikas et al. 2004) Continue reading "Process oriented Approach to S........ Read more »

Hallikas, J., Karvonen, I., Pulkkinen, U., Virolainen, V., & Tuominen, M. (2004) Risk management processes in supplier networks. International Journal of Production Economics, 90(1), 47-58. DOI: 10.1016/j.ijpe.2004.02.007  

  • January 24, 2011
  • 09:03 AM

Gian Giudice and Lisa Randall in Rome

by Marco Frasca in The Gauge Connection

As usual, also for this year there has been the Festival delle Scienze (Festival of the Sciences) in Rome. This lasted for all the last week and ended this sunday. This is the chance to hear from leading scientists the status of forefront research. This year’s theme was “The End of the World – Instructions [...]... Read more »

Lillie, B., Randall, L., & Wang, L. (2007) The Bulk RS KK-gluon at the LHC. Journal of High Energy Physics, 2007(09), 74-74. DOI: 10.1088/1126-6708/2007/09/074  

  • January 24, 2011
  • 08:32 AM

Rhea’s “Breathable” Atmosphere

by Ryan in The Martian Chronicles

Yesterday I came across this article, proclaiming to the world that "Saturn’s icy moon Rhea has an oxygen and carbon dioxide atmosphere that is very similar to Earth’s. Even better, the carbon dioxide suggests there’s life – and that possibly humans could breathe the air."

Say what? Ok. There's so much badness packed into those two lede sentences that I feel dirty just reprinting them here.... Read more »

Teolis BD, Jones GH, Miles PF, Tokar RL, Magee BA, Waite JH, Roussos E, Young DT, Crary FJ, Coates AJ.... (2010) Cassini finds an oxygen-carbon dioxide atmosphere at Saturn's icy moon Rhea. Science (New York, N.Y.), 330(6012), 1813-5. PMID: 21109635  

  • January 24, 2011
  • 08:00 AM

Conservation and the Concept of Species in a Biodiversity Crisis (Part 1)

by Southern Fried Scientist in Southern Fried Science

In The Mass Extinction of Scientists Who Study Species, Dr. Craig McClain argues that we are loosing a fundamental unit of biological science – the Taxonomist. He’s right, of course. Taxonomy is a shrinking field. Entire phyla sit, unstudied, as the expertise necessary to understand them retires and expires. With few to train the [...]... Read more »

Jody Hey. (2001) The mind of the species problem. TRENDS in Ecology and Evolution, 16(7), 326-329. info:/

  • January 24, 2011
  • 08:00 AM

Unexplained Variance of Obesity Levels Across Canada

by Arya M. Sharma in Dr. Sharma's Obesity Notes

As in most countries, the population levels of obesity in Canada vary considerably from province to province (as they do within provinces). Although there are many “theories” on why this may be the case there has been little work done on trying to unravel the “explained” and “unexplained” regional variation based on a comparison of [...]... Read more »

  • January 24, 2011
  • 08:00 AM

From the Editor’s Desk: The Grand Challenge of Ocean Acidification and Fisheries

by Kevin Zelnio in Deep Sea News

Anthropogenic climate change has been hypothesized for centuries (discussed in Le Treut 2007) before the careful measurements of scientists in the mid-20th century. From 1833 to 1997, Stanhill (2001) calculated that the climate change science doubled every 11 years. The impact of carbon dioxide concentrations in the ocean was recognized early on with measurements and . . . → Read More: From the Editor’s Desk: The Grand Challenge of Ocean Acidification and Fisheries... Read more »

Carpenter KE, Abrar M, Aeby G, Aronson RB, Banks S, Bruckner A, Chiriboga A, Cortés J, Delbeek JC, Devantier L.... (2008) One-third of reef-building corals face elevated extinction risk from climate change and local impacts. Science (New York, N.Y.), 321(5888), 560-3. PMID: 18653892  

Doney SC, Fabry VJ, Feely RA, & Kleypas JA. (2009) Ocean acidification: the other CO2 problem. Annual review of marine science, 169-92. PMID: 21141034  

Hall-Spencer J, Allain V, & Fosså JH. (2002) Trawling damage to Northeast Atlantic ancient coral reefs. Proceedings. Biological sciences / The Royal Society, 269(1490), 507-11. PMID: 11886643  

  • January 24, 2011
  • 08:00 AM

Scanning salmon smelling streams

by Zen Faulkes in NeuroDojo

You could be forgiven for thinking that there’s no way you could get a useful brain scan of a fish.

First all, if you pay attention to brain scanning, you have probably heard a story about fish in fMRI machines that has become the stuff of scientific legend. The salmon in question being scanned for brain activity was deceased. Pushing up daisies. Size feet under. Joined the choir invisible. In a word, dead.

Yet a brain scan revealed statistically significant brain activity.

Bennett and col........ Read more »

Bandoh H, Kida I, & Ueda H. (2011) Olfactory responses to natal stream water in sockeye salmon by BOLD fMRI. PLoS ONE, 6(1). info:/10.1371/ journal.pone.0016051

  • January 24, 2011
  • 07:38 AM

The Meaning Triangle

by David Winter in Careers - in Theory

As the post on existentialism has been one of my most popular, I thought I would do something more on the subject of meaningfulness. And when it comes to meaning, it seems that three is a magic number. But first a short story (involving three workers)… A traveller comes across a group of three men [...]... Read more »

  • January 24, 2011
  • 07:04 AM

Excuse me, potential juror, but just how big is your amygdala?

by Rita Handrich in The Jury Room

New research touts findings that conservatives have bigger amygdalas while liberals have bigger cingulate cortices. The bigger amygdala means conservatives could be driven by fear while the bigger cingulated cortex means liberals have more decision-making power. Hmmm. Is it possible that our politics are fixed at birth? Probably not. Neuroskeptic takes a look at the [...]

Related posts:Church attendance, dirt and politics (what we don’t know about ourselves)
“Reactions vary along tradi........ Read more »

Michael D. Dodd, John R. Hibbing, & Kevin B. Smith. (2010) The politics of attention: gaze-cuing effects are moderated by political temperament. Attention, Perception and Psychophysics. info:/

  • January 24, 2011
  • 07:00 AM

The Beauty of First Impressions

by Shaheen Lakhan in Brain Blogger

Oscar Wilde once claimed, “It is better to be beautiful than good, but it is better to be good than ugly.” This may be most true when meeting new people. Researchers in British Columbia suggest that beautiful people make better first impressions. In the study, people more accurately described and had a more positive impression [...]... Read more »

Schiller D, Freeman JB, Mitchell JP, Uleman JS, & Phelps EA. (2009) A neural mechanism of first impressions. Nature neuroscience, 12(4), 508-14. PMID: 19270690  

  • January 24, 2011
  • 07:00 AM

January 24, 2011

by Erin Campbell in HighMag Blog

When we first learned about the cell cycle in high school, we learned about the stunning simplicity of certain proteins that cycle in order to promote progression through the cell cycle. In reality, that picture is quite complex, with many layers of regulation that affect those cycling proteins. A recent paper from the Nurse lab pares down all of that complexity to show us that the simplicity really has been there all along. The cell cycle is the sequence of events that leads to a cell&rsq........ Read more »

  • January 24, 2011
  • 06:00 AM

Article Review: Online curriculum for non-EM residents in the ED

by Michelle Lin in Academic Life In Emergency Medicine

In many academic Emergency Departments, there are "off-service" or non-EM residents rotating in the department. They are sometimes invited to the EM residency conference series for the month. Often times though, they have too many departmental didactic events and obligations of their own that they don't have time to attend formal EM didactics.This is the perfect opportunity for an online didactic curriculum, which can be viewed at the residents' own time. The faculty at Northwestern designed suc........ Read more »

Branzetti JB, Aldeen AZ, Foster AW, & Mark Courtney D. (2010) A Novel Online Didactic Curriculum Helps Improve Knowledge Acquisition Among Non-Emergency Medicine Rotating Residents. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine. PMID: 21175925  

  • January 24, 2011
  • 05:27 AM

Globular Clusters and Voids

by Christine Corbett Moran in Cosmic Rays

In the morning when I get into lab, around 10 in the morning, I have a set routine. Make a cup of coffee or tea, update my research wiki with a new entry corresponding to the day’s tasks, write/reply to work related emails, admin (spam management etc.), scan/vote on papers of interest. Finally I [...]... Read more »

C. Y. Hui, K. S. Cheng, Y. Wang, P. H. T. Tam, A. K. H. Kong, D. O. Chernyshov, & V. A. Dogiel. (2011) The Fundamental Plane of Gamma-ray Globular Clusters. Astrophysical Journal, Volume 726, Page 100 (2011). arXiv: 1101.4107v1

R. van de Weygaert, K. Kreckel, E. Platen, B. Beygu, J. H. van Gorkom, J. M. van der Hulst, M. A. Aragon-Calvo, P. J. E. Peebles, T. Jarrett, G. Rhee.... (2011) The Void Galaxy Survey. "Environment and the Formation of Galaxies: 30 years later", Proceedings of Symposium 2 of JENAM 2010,. arXiv: 1101.4187v1

  • January 24, 2011
  • 05:22 AM

Other people may experience more misery than you realise

by BPS Research Digest in BPS Research Digest

You are not alone ...
Have you ever had the feeling that everyone else seems so sorted, so at ease? You look about you and see friends chatting over lunch, people laughing on their mobiles, others escaping contentedly through novels or newspapers. According to Alexander Jordan and colleagues, most of us have such a tendency to underestimate other people's experience of negative emotion. In turn the researchers think this skewed perception perpetuates a collective delusion in which we all striv........ Read more »

  • January 24, 2011
  • 05:00 AM

"With the Help of My Friends": Parasites Traveling in Packs.

by Nsikan Akpan in That's Basic Science

Curious Social Behavior in Trypanosomes ... Read more »

Oberholzer, M., Lopez, M., McLelland, B., & Hill, K. (2010) Social Motility in African Trypanosomes. PLoS Pathogens, 6(1). DOI: 10.1371/journal.ppat.1000739  

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